Abstract：
BACKGROUND:Dermatofibroma (DF) is a common benign skin lesion in a majority of cases located on the legs or upper limbs. The etiology of DF is still unclear. OBJECTIVES:Reflectance confocal microscopy features of DF were described. METHODS:Forty patients with DF diagnosis confirmed by dermoscopy were examined using reflectance confocal microscopy VivaScope 1500 from March 2018 to April 2019. RESULTS:DF was more common in females (80%) than males (20%). Thirty-six lesions (90%) were located on the limbs while four (10%) were on the trunk. Dermoscopically, 18 lesions (45%) revealed typical features: central white area with a brown network in the periphery. Twenty-two DFs (55%) were found with a central white patch and globular-like structures, surrounded by a thin brown network. In reflectance confocal microscopy, all revealed a typical honeycombed pattern, although in some cases (30%), streaming was observed. In two lesions (5%) in epidermis, few dendritic cells were observed, and one DF revealed roundish pagetoid cells (2.5%). The dermoepidermal junction (DEJ) in all lesions was abounded in dilated vessels. The most common observable feature of DF was bright "rings" composed of monomorphic, regular cells surrounding dark dermal papillae. In five lesions (12.5%), rings were "double" because of exceptionally pigmented DF. CONCLUSION:Reflectance confocal microscopy enables us to describe microscopic features of DF. There are four confocal microscopic features observable in each DF: in the epidermis, normal honeycombed pattern, sometimes with local streaming, in DEJ, edged papillae, bright rings, and dilated vessels.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Pogorzelska-Antkowiak A,Wcisło-Dziadecka D,Brzezińska-Wcisło L,Pawlicki K,Antkowiak R,Corneli Pdoi
10.1111/ijd.14972subject
Has Abstractpub_date
2020-08-01 00:00:00pages
951-954issue
8eissn
0011-9059issn
1365-4632journal_volume
59pub_type
杂志文章abstract：BACKGROUND:Mortality rates in patients with bullous pemphigoid (BP) are higher than those in age-matched counterparts. However, the specific causes of death in BP subjects have not been evaluated systematically. OBJECTIVES:We sought to characterize the causes of death in patients with BP as recorded by death certifica...
journal_title：International journal of dermatology
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journal_title：International journal of dermatology
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journal_title：International journal of dermatology
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doi：10.1111/j.1365-4362.1992.tb02722.x
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abstract：BACKGROUND:Dithranol is a potent reducing substance and is thought to achieve its effect on psoriasis by reduction of cell turnover. It was shown to be efficacious in adults, but its efficacy has not been documented in children. METHODS:The efficacy of short-contact therapy, a dithranol cream preparation, was retrospe...
journal_title：International journal of dermatology
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journal_title：International journal of dermatology
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journal_title：International journal of dermatology
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journal_title：International journal of dermatology
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journal_title：International journal of dermatology
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更新日期：2010-04-01 00:00:00
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更新日期：2009-02-01 00:00:00
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journal_title：International journal of dermatology
pub_type： 临床试验,杂志文章
doi：10.1046/j.1365-4362.2001.01242.x
更新日期：2001-06-01 00:00:00
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doi：10.1111/j.1365-4362.1985.tb05763.x
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