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Combination antiviral therapy with lopinavir/ritonavir, arbidol and interferon-α1b for COVID-19.

Abstract：

:Since the outbreak of coronavirus disease (COVID-19) that was discovered in 2019 in Wuhan, China, no standard therapy guideline has been set despite the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its high infectivity. The globally pandemic outbreak suggests that COVID-19 is highly infectious and difficult to control. A dual-combination of ribavirin and interferon-α has been the widely used regimen for the treatment of this disease in China. However, due to the varying results of treatment with these drugs, a novel antiviral combination therapy is urgently needed. This case reports the usage of lopinavir/ritonavir-based combination antiviral regimen for a patient with SARS-CoV-2 infection.

journal_name

Antivir Ther

journal_title

Antiviral therapy

authors

Xie X,Jiang Y,Zeng Y,Liu H

doi

10.3851/IMP3362

subject

Has Abstract

pub_date

2020-06-04 00:00:00

eissn

1359-6535

issn

2040-2058

pub_type

杂志文章

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