Abstract:
PURPOSE:Mitomycin C has been used in ophthalmic surgery to mitigate postoperative scarring. However, the outcomes of endoscopic-assisted probing for the treatment of congenital nasolacrimal duct obstruction with adjunctive mitomycin C in children remain unknown. Our study was aimed to evaluate the efficacy and safety of adjunctive application of mitomycin C after endoscopic-assisted probing for the treatment of congenital nasolacrimal duct obstruction in children. METHODS:This is a retrospective chart review performed in a tertiary eye care hospital involving children with congenital nasolacrimal duct obstruction, who underwent endoscopic-assisted probing from October 2013 to August 2015. We compared children who underwent endoscopic-assisted probing with mitomycin C (mitomycin C group) versus others who underwent endoscopic-assisted probing without mitomycin C (endoscopic-assisted probing group). The mitomycin C group received 0.2 mg/ml within 4 min to the nasolacrimal duct ostium using a cotton tip applicator immediately after probing. Probing was considered successful when patient complaints of tearing were reduced or the results of the dye disappearance test were normal. Demographic data, clinical features, and intraoperative and postoperative variables were correlated to the success rate. RESULTS:The study sample comprised 68 lacrimal vies. The majority of children had bilateral obstruction and no previous history of probing. The mean age of the patients was approximately 4 years. Most obstructions were considered complex. The success rates were high in both groups (p>0.05). There were no adverse events related to the use of mitomycin C (p>0.05). CONCLUSIONS:Although mitomycin C has no adverse effects when applied to the opening of the nasolacrimal duct, its use after lacrimal probing for the treatment of congenital nasolacrimal duct obstruction does not improve the chance of success.
journal_name
Arq Bras Oftalmoljournal_title
Arquivos brasileiros de oftalmologiaauthors
Galindo-Ferreiro A,Khandekar R,Akaishi PM,Cruz AAV,Galvez-Ruiz A,Dolmetsch A,Schellini SAdoi
10.5935/0004-2749.20200062subject
Has Abstractpub_date
2020-06-01 00:00:00pages
229-235issue
3eissn
0004-2749issn
1678-2925pii
S0004-27492020000300011journal_volume
83pub_type
杂志文章abstract::The authors describe an unusual association between posterior keratoconus and iris atrophy, confirmed by a complete ocular evaluation, scheimpflug imaging and pachymetric curve. A hypothesis for concomitant findings is discussed. ...
journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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