Abstract:
OBJECTIVES:We assessed the periodontal situation radiologically according to tumour p16 status. MATERIALS AND METHODS:Patients with a diagnosis of tonsillar cancer and availability of a digital panoramic radiograph (DPR) during a 5-year period were included in this retrospective study. The predictor variables were periodontal stability, marginal bone loss, marginal bone loss without periodontal stability and total number of teeth. Periodontal status was compared with p16 status, age, gender, smoking and alcohol use. RESULTS:Among 115 patients included in the analyses (p16-negative, n = 24; p16-positive, n = 91), smoking (p < .0001), heavy alcohol use (p < .0001) and total number of teeth (p = .0001) were significantly associated with p16 status. Current smoking (OR = 7.3) and heavy alcohol use (OR = 10.1) increased the risk of p16-negative cancer. CONCLUSIONS:Patients with p16-negative tonsillar carcinoma had less teeth than patients with p16-positive tumours. Other periodontal findings were common in both groups without statistical significance. Heavy alcohol use and smoking were the most important risk factors for p16-negative tonsillar carcinoma.
journal_name
Oral Disjournal_title
Oral diseasesauthors
Keinänen A,Marinescu-Gava M,Uittamo J,Hagström J,Marttila E,Snäll Jdoi
10.1111/odi.13437subject
Has Abstractpub_date
2020-11-01 00:00:00pages
1625-1630issue
8eissn
1354-523Xissn
1601-0825journal_volume
26pub_type
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