Abstract:
INTRODUCTION:Chronic breathlessness is associated with poorer quality of life (QoL). This population study aimed to define dimensions of QoL and duration and dominant causes of breathlessness that most diminished QoL. METHODS:This cross-sectional, population-based, and randomized survey of adults (n = 2977) in South Australia collected data on demographics, modified Medical Research Council (mMRC) breathlessness, and QoL (EuroQoL five-dimension five-level [EQ-5D-5L] measure; Short Form 12 quality-of-life measure). Data weighted to the census were analyzed for relationships between EQ-5D-5L and its dimensions with mMRC. Regression models controlled for age, sex, education, rurality, and body mass index. RESULTS:About 2883 responses were analyzed: 49% were males; mean age was 48 years (SD 19). As mMRC worsened, EQ-5D-5L and its dimensions worsened. More severe chronic breathlessness was iteratively associated with lower mobility, daily activities, and worse pain/discomfort. For self-care and anxiety/depression, impairment was only with the most severe breathlessness. Respondents who had chronic breathlessness for two to six years had the worst QoL scores. People who attributed their breathlessness to cardiac failure had poorer QoL. Respondents who reported a cardiac cause for their breathlessness had worse mobility, poorer usual activities, and more pain than the other causes. The regression analyses showed that worse chronic breathlessness was associated with worsening QoL in each dimension of EQ-5D-5L, with the exception of the self-care, which only worsened with the most severe breathlessness. CONCLUSIONS:This is the first study to report on chronic breathlessness and impairment across dimensions of QoL and differences by its duration. Mobility, usual activity, and pain drive these reductions.
journal_name
J Pain Symptom Managejournal_title
Journal of pain and symptom managementauthors
Currow DC,Chang S,Grande ED,Ferreira DH,Kochovska S,Kinchin I,Johnson MJ,Ekstrom Mdoi
10.1016/j.jpainsymman.2020.05.015subject
Has Abstractpub_date
2020-10-01 00:00:00pages
818-827.e4issue
4eissn
0885-3924issn
1873-6513pii
S0885-3924(20)30395-Xjournal_volume
60pub_type
杂志文章abstract:CONTEXT:There are no previously published studies examining opioid doses administered to opioid-tolerant cancer patients during emergency department (ED) encounters. OBJECTIVES:To determine if opioid-tolerant cancer patients presenting with acute pain exacerbations receive adequate initial doses of as needed (PRN) opi...
journal_title:Journal of pain and symptom management
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jpainsymman.2017.07.013
更新日期:2017-10-01 00:00:00
abstract::Fatigue is among the most distressing symptoms experienced by terminally ill cancer patients. It is necessary to clarify factors correlated with fatigue to develop effective management strategies. A consecutive sample of cancer patients newly registered in the Palliative Care Unit (PCU) was assessed on three occasions...
journal_title:Journal of pain and symptom management
pub_type: 杂志文章
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abstract::Dexamethasone is likely to play a role in the etiology of hiccups in patients receiving cisplatin-based regimens. Two hundred seventy-seven patients received three doses of ondansetron 8mg intravenously (IV) at 4hour intervals plus dexamethasone 20mg IV from the start of chemotherapy, followed by dexamethasone 5mg IV ...
journal_title:Journal of pain and symptom management
pub_type: 临床试验,杂志文章
doi:10.1016/j.jpainsymman.2005.08.008
更新日期:2005-10-01 00:00:00
abstract:CONTEXT:The use of unidimensional pain scales such as the Numerical Rating Scale (NRS), Verbal Rating Scale (VRS), or Visual Analogue Scale (VAS) is recommended for assessment of pain intensity (PI). A literature review of studies specifically comparing the NRS, VRS, and/or VAS for unidimensional self-report of PI was ...
journal_title:Journal of pain and symptom management
pub_type: 杂志文章,评审
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abstract::The effect of iontophoretic administration of vincristine in the treatment of postherpetic neuralgia (PHN) was investigated in a prospective, double-blind, placebo-controlled trial. Twenty patients with intercostal or lumbar PHN for more than 6 months that was unresponsive to conventional medical therapy were randomiz...
journal_title:Journal of pain and symptom management
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章
doi:10.1016/0885-3924(94)90129-5
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章
doi:10.1016/j.jpainsymman.2008.02.013
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abstract:BACKGROUND:Few patients with dysphagia because of stroke receive early palliative care (PC) to align treatment goals with their values, as called for by practice guidelines, particularly before enteral access procedures for artificial nutrition. MEASURES:To increase documented goals of care (GOC) discussions among acu...
journal_title:Journal of pain and symptom management
pub_type: 杂志文章
doi:10.1016/j.jpainsymman.2018.06.010
更新日期:2018-10-01 00:00:00
abstract::Palliative care aims to improve the quality of life of patients and their families and reduce suffering from life-threatening illness. In assessing palliative care efficacy, researchers must consider a broad range of potential outcomes, including those experienced by the patient's family/caregivers, clinicians, and th...
journal_title:Journal of pain and symptom management
pub_type: 共识发展会议,杂志文章
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章,评审
doi:10.1016/0885-3924(95)00007-L
更新日期:1995-05-01 00:00:00
abstract::A retrospective analysis was performed to study the occurrence and treatment of death rattle (DR) in 107 consecutive dying patients on the palliative care unit of the University Hospital Leuven. The incidence of DR (23%) is lower than reported in literature, possibly due to low hydration. We found 2 types of rattle: "...
journal_title:Journal of pain and symptom management
pub_type: 临床试验,杂志文章
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更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Intensive care unit (ICU) care could be improved by implementation of time-triggered evidence-based interventions including identification of a patient/family medical decision maker, the patient's advance directive status, and cardiopulmonary resuscitation preferences by Day 1; offer of social work and spiri...
journal_title:Journal of pain and symptom management
pub_type: 杂志文章
doi:10.1016/j.jpainsymman.2011.06.012
更新日期:2011-11-01 00:00:00
abstract::This study compared the effects of nebulized versus subcutaneous morphine on the intensity of dyspnea in cancer patients. Patients with a resting dyspnea intensity > or =3 on a 0-10 scale (0=no dyspnea, 10=worst possible dyspnea) who received regular oral or parenteral opioids were included. On day 1, patients receive...
journal_title:Journal of pain and symptom management
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.jpainsymman.2004.08.016
更新日期:2005-06-01 00:00:00
abstract:CONTEXT:Intermountain Healthcare, in collaboration with Cerner Corporation, developed a hospital-based electronic palliative care algorithm. OBJECTIVES:This study aims to improve identification of patients who would benefit from palliative care services, and calculate palliative care penetration rates. METHODS:This s...
journal_title:Journal of pain and symptom management
pub_type: 杂志文章
doi:10.1016/j.jpainsymman.2017.09.013
更新日期:2018-02-01 00:00:00
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jpainsymman.2014.10.010
更新日期:2015-05-01 00:00:00
abstract::A significant proportion of health care resources are consumed at end of life. As a result, decision and policy makers seek cost savings to enhance program planning. Most literature, however, combines the cost of all dying patients and, subsequently, fails to recognize the variation between trajectories of functional ...
journal_title:Journal of pain and symptom management
pub_type: 杂志文章
doi:10.1016/j.jpainsymman.2009.04.007
更新日期:2009-07-01 00:00:00
abstract::Many patients with advanced malignancy develop bone metastases, pathologic fractures, and skin breakdown, all of which compromise comfort and interfere with the delivery of patient care. In 1986, 38 Clinitron beds were utilized at Calvary Hospital, a specialty hospital for advanced cancer, for patients who were immobi...
journal_title:Journal of pain and symptom management
pub_type: 杂志文章
doi:10.1016/s0885-3924(05)80009-0
更新日期:1990-02-01 00:00:00
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章
doi:10.1016/j.jpainsymman.2010.05.016
更新日期:2011-02-01 00:00:00
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章
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更新日期:2010-01-01 00:00:00
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章,评审
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章,meta分析,评审
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更新日期:2016-06-01 00:00:00
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章
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journal_title:Journal of pain and symptom management
pub_type: 杂志文章
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journal_title:Journal of pain and symptom management
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journal_title:Journal of pain and symptom management
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1996-03-01 00:00:00
abstract::To identify aspects of end-of-life care in the U.S. Department of Veterans Affairs (VA) health care system that are not assessed by existing survey instruments and to identify issues that may be unique to veterans, telephone interviews using open-ended questions were conducted with family members of veterans who had r...
journal_title:Journal of pain and symptom management
pub_type: 杂志文章
doi:10.1016/j.jpainsymman.2007.03.008
更新日期:2008-02-01 00:00:00