Marine-derived Polyaromatic Butenolides - Isolation, Synthesis and Biological Evaluations.

Abstract:

:Marine invertebrates, especially tunicates, are a lucrative resource for the discovery of new lead compounds for the development of clinically utilized drugs. This review describes the isolation, synthesis and biological activities of several classes of marine-derived butenolide natural products, namely rubrolides and related cadiolides and prunolides. All relevant studies pertaining to these compounds up to the end of 2019 are included.

journal_name

Curr Pharm Des

authors

Bracegirdle J,Keyzers RA

doi

10.2174/1381612826666200518110617

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

4351-4361

issue

35

eissn

1381-6128

issn

1873-4286

pii

CPD-EPUB-106744

journal_volume

26

pub_type

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