Pharyngeal Swallowing Pressures in Patients with Radiation-Associated Dysphagia.

Abstract:

:Dysphagia associated with radiotherapy for head and neck cancer is complex and can be difficult to treat. Videofluoroscopic swallow studies (VFSS) are the current gold-standard instrumented swallow assessment. High-resolution manometry (HRM) is an additional approach that provides objective measurements of swallowing-related pressures in the pharynx and esophagus. This can provide functional information on the pressure gradients underlying bolus propulsion, and is relevant for this patient population, where radiation-related fibrosis can lead to weakness and impaired pressure generation. The purpose of this preliminary study was to describe pharyngeal swallowing pressures in patients with radiation-associated dysphagia (RAD) and late radiation-associated dysphagia (LRAD) using HRM. RAD occurs during and immediately following treatment, whereas LRAD is a more recently described phenomenon in which the patient experiences an onset of dysphagia at least 5 years post-treatment. We performed a retrospective analysis of pharyngeal swallowing pressures from 21 patients with RAD or LRAD and 21 healthy sex/age-matched controls. Patients with RAD or LRAD exhibited decreased swallowing pressure durations throughout the pharynx (p ≤ 0.002), as well as decreased hypopharynx maximum pressure (p = 0.003) and pharyngeal contractile integral ( p < 0.0001). Understanding how pharyngeal pressure generation is altered in patients with a history of radiotherapy can help clinicians form more precise treatment plans.

journal_name

Dysphagia

journal_title

Dysphagia

authors

Schaen-Heacock NE,Jones CA,McCulloch TM

doi

10.1007/s00455-020-10128-9

subject

Has Abstract

pub_date

2020-05-15 00:00:00

eissn

0179-051X

issn

1432-0460

pii

10.1007/s00455-020-10128-9

pub_type

杂志文章
  • Kinematic pharyngeal transit times in myopathy: evaluation for dysphagia.

    abstract::Measurement of kinematic pharyngeal transit times, a new videofluoroscopy technique, provides useful quantitative data to supplement the qualitative data previously available from videofluoroscopy swallowing studies. Kinematic pharyngeal transit times have not previously been reported for subjects with myopathy. This ...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/BF01351476

    authors: Johnson ER,McKenzie SW

    更新日期:1993-01-01 00:00:00

  • Timing of videofluoroscopic, manometric events, and bolus transit during the oral and pharyngeal phases of swallowing.

    abstract::The aims of this study were to evaluate and quantify the timing of events associated with the oral and pharyngeal phases of liquid swallows. For this purpose, we recorded 0-20 ml barium swallows in three groups of volunteers using videoradiographic, electromyographic, and manometric methods. The study findings indicat...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/BF02407397

    authors: Cook IJ,Dodds WJ,Dantas RO,Kern MK,Massey BT,Shaker R,Hogan WJ

    更新日期:1989-01-01 00:00:00

  • Tongue pressure patterns during water swallowing.

    abstract::Bolus propulsion during the normal oral phase of swallowing is thought to be characterised by the sequential elevation of the front, middle, and posterior regions of the dorsum of the tongue. However, the coordinated orchestration of lingual movement is still poorly understood. This study examined how pressures genera...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-009-9223-2

    authors: Kennedy D,Kieser J,Bolter C,Swain M,Singh B,Waddell JN

    更新日期:2010-03-01 00:00:00

  • A Meta-Analysis of the Incidence of Patient-Reported Dysphagia After Anterior Cervical Decompression and Fusion with the Zero-Profile Implant System.

    abstract::Dysphagia is a well-known complication following anterior cervical surgery. It has been reported that the Zero-profile Implant System can decrease the incidence of dysphagia following surgery, however, dysphagia after anterior cervical decompression and fusion (ACDF) with the Zero-profile Implant System remains contro...

    journal_title:Dysphagia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00455-015-9681-7

    authors: Yang Y,Ma L,Liu H,Xu M

    更新日期:2016-04-01 00:00:00

  • Anterior cervical osteophytes causing dysphagia and dyspnea: an uncommon entity revisited.

    abstract::Large anterior cervical osteophytes can occur in degeneration of the cervical spine or in diffuse idiopathic skeletal hyperostosis (DISH). We present the case of an 83-year-old patient with progressive dysphagia and acute dyspnea, necessitating emergency tracheotomy. Voluminous anterior cervical osteophytes extending ...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-006-9049-0

    authors: Giger R,Dulguerov P,Payer M

    更新日期:2006-10-01 00:00:00

  • Assessment of swallowing by oropharyngoesophageal scintigraphy in patients with amyotrophic lateral sclerosis.

    abstract::Amyotrophic lateral sclerosis (ALS) is the most common degenerative motor neuron disease in adults, and dysphagia is one of its most frequent and disabling symptoms. Oropharyngoesophageal scintigraphy (OPES) permits a functional and semiquantitative study of the various stages of swallowing. We studied 28 ALS patients...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-006-9052-5

    authors: Fattori B,Grosso M,Bongioanni P,Nacci A,Cristofani R,AlSharif A,Licitra R,Matteucci F,Rossi B,Rubello D,Ursino F,Mariani G

    更新日期:2006-10-01 00:00:00

  • Earliest videofluoromanometric pharyngeal signs of dysphagia in ALS patients.

    abstract::The aim of this study was to find whether there are manometric pharyngeal changes that may have diagnostic and prognostic relevance in the amyotrophic lateral sclerosis (ALS) patient who does not show changes in contrast-medium oropharyngeal transit in a videofluoroscopic swallowing study. Ten ALS patients, with an AL...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-014-9542-9

    authors: Solazzo A,Monaco L,Vecchio LD,Reginelli A,Iacobellis F,Capasso R,Tamburrini S,Berritto D,Barillari MR,Monsurrò MR,Di Martino N,Grassi R

    更新日期:2014-10-01 00:00:00

  • Correlation Between EAT-10 and Aspiration Risk Differs by Dysphagia Etiology.

    abstract::Agreement between self-reported dysphagic symptoms and actual swallowing physiology can vary widely across individuals. The Eating Assessment Tool-10 (EAT-10) is a self-report questionnaire commonly used to identify individuals with oropharyngeal dysphagia, but its interpretation for highly prevalent populations is po...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-021-10244-0

    authors: Bartlett RS,Kenz MK,Wayment HA,Thibeault SL

    更新日期:2021-01-24 00:00:00

  • Within-Bolus Variability of the Penetration-Aspiration Scale Across Two Subsequent Swallows in Patients with Head and Neck Cancer.

    abstract::To compare two consecutive swallowing attempts to study if there is a difference in Rosenbek's penetration-aspiration scale (PAS) scores between the first and second swallowing attempt of the same bolus type in videofluoroscopic examination of swallowing (VFS). Additional aims include reflecting on which bolus sizes a...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-017-9814-2

    authors: Hedström J,Tuomi L,Andersson M,Dotevall H,Osbeck H,Finizia C

    更新日期:2017-10-01 00:00:00

  • Moving Forward with Dysphagia Care: Implementing Strategies during the COVID-19 Pandemic and Beyond.

    abstract::Growing numbers of SARS-CoV-2 cases coupled with limited understanding of transmissibility and virulence, have challenged the current workflow and clinical care pathways for the dysphagia provider. At the same time, the need for non-COVID-19-related dysphagia care persists. Increased awareness of asymptomatic virus ca...

    journal_title:Dysphagia

    pub_type: 杂志文章,评审

    doi:10.1007/s00455-020-10144-9

    authors: Fritz MA,Howell RJ,Brodsky MB,Suiter DM,Dhar SI,Rameau A,Richard T,Skelley M,Ashford JR,O'Rourke AK,Kuhn MA

    更新日期:2020-06-09 00:00:00

  • Vocal Fold Paralysis/Paresis as a Marker for Poor Swallowing Outcomes After Thoracic Surgery Procedures.

    abstract::(1) To examine the association between vocal fold paresis/paralysis (VFP) and poor swallowing outcomes in a thoracic surgery cohort at the population level, and (2) to assess utilization of ENT/speech-language pathology intervention in these cases. The National Inpatient Sample (NIS) represents a 20% stratified sample...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-019-09987-8

    authors: Crowson MG,Tong BC,Lee HJ,Song Y,Misono S,Jones HN,Cohen S

    更新日期:2019-12-01 00:00:00

  • Residual Recurrent Nerve Paralysis After Esophagectomy is Associated with Preoperative Lower Serum Albumin.

    abstract::Esophagectomy for esophageal cancer is invasive thoracic surgery with a high incidence rate of postoperative complications and prolongation of hospitalization, even if the standardized clinical pathway improves the outcome (mortality and morbidity). Postoperative recurrent nerve paralysis (RNP) is related to respirato...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-017-9793-3

    authors: Miyamoto M,Kobayashi Y,Miyata E,Sakagami T,Yagi M,Kanda A,Michiura T,Tomoda K

    更新日期:2017-08-01 00:00:00

  • Preliminary ultrasound observation of lingual movement patterns during nutritive versus non-nutritive sucking in a premature infant.

    abstract::Term neonates must suck, swallow, and respire in a coordinated manner during successful oral feeding. When infants are born prematurely, these skills may not be fully mature. To stimulate sucking responses, premature infants are offered pacifiers under the premise that non-nutritive sucking experiences facilitate oral...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-006-9058-z

    authors: Miller JL,Kang SM

    更新日期:2007-04-01 00:00:00

  • A new application for electropalatography: swallowing.

    abstract::Electropalatography (EPG) has been applied to linguistic research and speech pathology. This study evaluated whether EPG could provide useful information on swallow-related tongue action. Specifically, the investigation focused on the quantification of tongue-palate contact patterns for swallowing and on the effects o...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/BF00265208

    authors: Chi-Fishman G,Stone M

    更新日期:1996-10-01 00:00:00

  • Clinical Characteristics and Lesions Responsible for Swallowing Hesitation After Acute Cerebral Infarction.

    abstract::Some stroke patients with a unilateral lesion demonstrate acute dysphagia characterized by a markedly prolonged swallowing time, making us think they are reluctant to swallow. In order to clarify the clinical characteristics and causative lesions of delayed swallowing, we conducted a retrospective analysis of 20 right...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-016-9716-8

    authors: Saito T,Hayashi K,Nakazawa H,Ota T

    更新日期:2016-08-01 00:00:00

  • Clinical and radiologic evaluation reveals high prevalence of abnormalities in young adults with dysphagia.

    abstract::The purpose of this study was to retrospectively evaluate the radiologic findings in young adults with dysphagia undergoing barium swallow and to compare these with the final clinical diagnosis. Clinical history, barium swallow, endoscopy (21 patients), manometry (18 patients), 24 h pH monitoring (4 patients), and out...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/PL00009572

    authors: Lundquist A,Olsson R,Ekberg O

    更新日期:1998-10-01 00:00:00

  • Long-term results of external upper esophageal sphincter myotomy for oropharyngeal Dysphagia.

    abstract::The aim of this work was to assess the efficacy of external myotomy of the upper esophageal sphincter (UES) for oropharyngeal dysphagia. In the period 1991-2006, 28 patients with longstanding dysphagia and/or aspiration problems of different etiologies underwent UES myotomy as a single surgical treatment. The main sym...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-009-9236-x

    authors: Kos MP,David EF,Klinkenberg-Knol EC,Mahieu HF

    更新日期:2010-09-01 00:00:00

  • Potential for Volitional Control of Resting Pressure at the Upper Oesophageal Sphincter in Healthy Individuals.

    abstract::Resting pressure at the upper oesophageal sphincter (UOS) has been reported to be susceptible to factors such as emotional stress or respiration. This exploratory study investigated the potential for behavioural modulation of UOS resting pressure in healthy adults to increase our understanding of volitional control of...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-020-10146-7

    authors: Winiker K,Gozdzikowska K,Guiu Hernandez E,Kwong SL,Macrae P,Huckabee ML

    更新日期:2020-06-18 00:00:00

  • Dysphagia in Multiple Sclerosis: Evaluation and Validation of the DYMUS Questionnaire.

    abstract:OBJECTIVE:The 10-item Dysphagia in Multiple Sclerosis (DYMUS) questionnaire is a self-administered tool used to identify swallowing problems in adults with MS. The questionnaire was not validated against other existing questionnaires to assess its convergent validity. Moreover, its test-retest reliability was not measu...

    journal_title:Dysphagia

    pub_type: 杂志文章,评审

    doi:10.1007/s00455-017-9864-5

    authors: Alali D,Ballard K,Vucic S,Bogaardt H

    更新日期:2018-06-01 00:00:00

  • Promoting safe swallowing when puree is swallowed without aspiration but thin liquid is aspirated: nectar is enough.

    abstract::The use of thickened liquids is a common compensatory strategy to improve swallow safety. The purpose of this study was to determine the optimal liquid viscosity to use to promote successful swallowing in a specific subset of dysphagic patients who swallow puree without aspiration but thin liquid with aspiration. A re...

    journal_title:Dysphagia

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00455-012-9412-2

    authors: Leder SB,Judson BL,Sliwinski E,Madson L

    更新日期:2013-03-01 00:00:00

  • Reliable lip force measurement in healthy controls and in patients with stroke: a methodologic study.

    abstract::A prefabricated oral screen has shown promising results as a muscle self-training device to improve the lip function of stroke patients affected by oropharyngeal dysphagia. However, a technique for the measurement of lip muscle force, whether in healthy individuals or in stroke patients, is lacking. The present study ...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-007-9143-y

    authors: Hägg M,Olgarsson M,Anniko M

    更新日期:2008-09-01 00:00:00

  • Use of the Penetration-Aspiration Scale in Dysphagia Research: A Systematic Review.

    abstract::The penetration-aspiration scale (PAS) is an 8-point scale used to characterize the depth and response to airway invasion during videofluoroscopy. Though widely used in the field of deglutition, there is a lack of consensus regarding the statistical properties of the scale. In order to better understand the state of t...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-019-10064-3

    authors: Borders JC,Brates D

    更新日期:2020-08-01 00:00:00

  • Associations between laryngeal and cough dysfunction in motor neuron disease with bulbar involvement.

    abstract::True vocal fold (TVF) dysfunction may lead to cough ineffectiveness. In individuals with motor neuron disease (MND), cough impairment in the context of dysphagia increases risk for aspiration and respiratory failure. This study characterizes differences and associations between TVF kinematics and airflow during cough ...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-014-9554-5

    authors: Britton D,Benditt JO,Merati AL,Miller RM,Stepp CE,Boitano L,Hu A,Ciol MA,Yorkston KM

    更新日期:2014-12-01 00:00:00

  • Sequential swallowing of liquid in elderly adults: cup or straw?

    abstract::This article describes the study of the characteristics of sequential swallowing of 100 ml of liquid (dyed water) in two swallowing trials, directly from a cup and through a straw, in healthy elderly individuals. The aim of the study was to determine whether differences in the swallowing pattern are influenced by the ...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-013-9503-8

    authors: Veiga HP,Fonseca HV,Bianchini EM

    更新日期:2014-04-01 00:00:00

  • Isolated proximal esophageal injury from blunt trauma: endoscopic stricture dilatation.

    abstract::Blunt neck trauma can cause isolated esophageal injuries that may be difficult to recognize. A high index of suspicion is necessary for optimal identification and management of this condition. We report a case of blunt esophageal trauma resulting from a motor vehicle accident that was initially unrecognized until the ...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-003-0008-8

    authors: Pineau BC,Ott DJ

    更新日期:2003-10-01 00:00:00

  • The role of the insular cortex in dysphagia.

    abstract::Recent data indicate that dysphagia may occur following unilateral cortical stroke; however, the elucidation of specific cytoarchitectonic sites that produce deglutition disorders remains unclear. In a previous study of unilateral cortical stroke patients with dysphagia, Daniels et al. proposed that the insula may be ...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/PL00009529

    authors: Daniels SK,Foundas AL

    更新日期:1997-07-01 00:00:00

  • Conservative management of a large postlaryngectomy neopharyngeal diverticulum.

    abstract::Dysphagia is common following total laryngectomy. Postlaryngectomy neopharyngeal diverticulae are known to cause postlaryngectomy dysphagia but are more frequently asymptomatic. We report a case presenting with late-onset postlaryngectomy dysphagia and a suprastomal swelling secondary to such a diverticulum. The patie...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-004-0015-4

    authors: Montague ML,Davis BC,Riad M

    更新日期:2004-10-01 00:00:00

  • Effects of consistent food presentation on efficiency of eating and nutritive value of food consumed by children with severe neurological impairment.

    abstract::The purpose of this investigation was to determine what implications consistent presentation of food, delivered by an assistive feeding device at a position regarded as optimal, would have for the maintenance of food intake, duration of meals, and efficiency of eating. The trial employed an AB within-subjects design a...

    journal_title:Dysphagia

    pub_type: 临床试验,杂志文章

    doi:10.1007/PL00009580

    authors: Pinnington L,Hegarty J

    更新日期:1999-01-01 00:00:00

  • Differential Response Pattern of Oropharyngeal Pressure by Bolus and Dry Swallows.

    abstract::The aim of this study was to determine if bolus and dry swallow showed similar pressure changes in the oropharynx using our newly developed device. A unique character of it includes that baropressure can be measured with the sensor being placed in the balloon and can assess the swallowing mechanics in terms of pressur...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-017-9836-9

    authors: Hasegawa M,Kurose M,Okamoto K,Yamada Y,Tsujimura T,Inoue M,Sato T,Narumi T,Fujii N,Yamamura K

    更新日期:2018-02-01 00:00:00

  • Esophageal Function Tests are Not Associated with Barium Swallow Findings in Advanced Lung Disease.

    abstract::Gastroesophageal reflux disease and esophageal dysmotility are common in patients with advanced lung disease (ALD) and are associated with worse outcomes. Assessing esophageal function in these patients is relevant for determining pulmonary transplant eligibility and prognosticating post-transplant outcomes. Barium Sw...

    journal_title:Dysphagia

    pub_type: 杂志文章

    doi:10.1007/s00455-020-10113-2

    authors: Posner S,Mehta K,Parish A,Niedzwiecki D,Gupta RT,Fisher DA,Leiman DA

    更新日期:2020-10-01 00:00:00