Abstract:
OBJECTIVE:To assess left ventricular remodeling patterns using cardiac computed tomography (CT) in children with congenital heart disease and correlate these patterns with their clinical course. MATERIALS AND METHODS:Left ventricular volume and myocardial mass were quantified in 17 children with congenital heart disease who underwent initial and follow-up end-systolic cardiac CT studies with a mean follow-up duration of 8.4 ± 9.7 months. Based on changes in the indexed left ventricular myocardial mass (LVMi) and left ventricular mass-volume ratio (LVMVR), left ventricular remodeling between the two serial cardiac CT examinations was categorized into one of four patterns: pattern 1, increased LVMi and increased LVMVR; pattern 2, decreased LVMi and decreased LVMVR; pattern 3, increased LVMi and decreased LVMVR; and pattern 4, decreased LVMi and increased LVMVR. Left ventricular remodeling patterns were correlated with unfavorable clinical courses. RESULTS:Baseline LVMi and LVMVR were 65.1 ± 37.9 g/m² and 4.0 ± 3.2 g/mL, respectively. LVMi increased in 10 patients and decreased in seven patients. LVMVR increased in seven patients and decreased in 10 patients. Pattern 1 was observed in seven patients, pattern 2 in seven, and pattern 3 in three patients. Unfavorable events were observed in 29% (2/7) of patients with pattern 1 and 67% (2/3) of patients with pattern 3, but no such events occurred in pattern 2 during the follow-up period (4.4 ± 2.7 years). CONCLUSION:Left ventricular remodeling patterns can be characterized using cardiac CT in children with congenital heart disease and may be used to predict their clinical course.
journal_name
Korean J Radioljournal_title
Korean journal of radiologyauthors
Goo HW,Park SHdoi
10.3348/kjr.2019.0689subject
Has Abstractpub_date
2020-06-01 00:00:00pages
717-725issue
6eissn
1229-6929issn
2005-8330pii
21.717journal_volume
21pub_type
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2012.13.6.720
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journal_title:Korean journal of radiology
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journal_title:Korean journal of radiology
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journal_title:Korean journal of radiology
pub_type: 杂志文章
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更新日期:2003-10-01 00:00:00
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更新日期:2002-04-01 00:00:00
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更新日期:2015-07-01 00:00:00
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更新日期:2010-09-01 00:00:00
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