The Trouble With Group 3 Pulmonary Hypertension in Interstitial Lung Disease: Dilemmas in Diagnosis and the Conundrum of Treatment.

abstract：:A five-year clinical follow-up and the results of myocardial biopsies are described in a patient with primary restrictive cardiomyopathy. Histologic examination of a right ventricular endomyocardial biopsy taken early in the course of the illness was not contributory. Histologic examination of a left ventricular endom...

journal_title：Chest

authors： Arbustini E,Buonanno C,Trevi G,Pennelli N,Ferrans VJ,Thiene G

更新日期：1983-08-01 00:00:00

abstract：:Bronchial thermoplasty (BT) involves the application of radiofrequency energy to visible proximal airways to selectively ablate airway smooth muscle. BT is the first nonpharmacologic interventional therapy approved by the US Food and Drug Administration (FDA) for severe asthma. This approval was based on the results o...

journal_title：Chest

authors： Iyer VN,Lim KG

更新日期：2014-07-01 00:00:00

abstract：:The results of computed chest tomograms (CT) and chest roentgenograms (CR) were compared in 32 patients who presented with hemoptysis. The CT demonstrated roentgenographic abnormalities more often than CR (p less than 0.01), providing new diagnostic information in 15 patients (46.9 percent), and clarifying CR abnormal...

journal_title：Chest

authors： Haponik EF,Britt EJ,Smith PL,Bleecker ER

更新日期：1987-01-01 00:00:00

abstract：:Lung volume reduction surgery (LVRS) is being evaluated in the treatment of emphysema. The proposed mechanisms of improvement are increased elastic recoil of the lung and improved mechanical efficiency of the muscles of respiration. We report a unique patient with emphysema who developed a giant bulla 3 years subseque...

journal_title：Chest

authors： Iqbal M,Rossoff L,McKeon K,Graver M,Scharf SM

更新日期：1999-12-01 00:00:00

abstract：:This chapter about implementation strategies for practice guidelines is part of the 7th ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based Guidelines. Grade 1 recommendations are strong and indicate that the benefits do, or do not, outweigh risks, burden, and costs. Grade 2 suggests that feasib...

journal_title：Chest

authors： Schünemann HJ,Cook D,Grimshaw J,Liberati A,Heffner J,Tapson V,Guyatt G

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Induced sputum cytology and protein biomarkers can be used to assess airways inflammation. Increases in sputum iron have been described in inflammatory lung disease. We hypothesized that other sputum metals may be affected by airways inflammation and investigated their potential value as biomarkers. METHODS...

journal_title：Chest

authors： Gray RD,Duncan A,Noble D,Imrie M,O'Reilly DS,Innes JA,Porteous DJ,Greening AP,Boyd AC

更新日期：2010-03-01 00:00:00

abstract：:Prosthetic valve endocarditis is a formidable complication following cardiac valve replacement. Surgical intervention has resulted in a significant reduction in mortality when certain complications prevail. We report two such cases of prosthetic valve endocarditis in which the use of transesophageal echocardiography p...

journal_title：Chest

authors： Bruss J,Jacobs LE,Kotler MN,Ioli AW

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVES:To investigate the time course and the relation to prognosis of coagulation and fibrinolytic abnormalities in patients with septic shock. PATIENTS AND METHODS:Forty-eight consecutive patients admitted to the medical ICU with the diagnosis of septic shock (diagnosed by defined criteria) were studied. Mortali...

journal_title：Chest

authors： Lorente JA,García-Frade LJ,Landín L,de Pablo R,Torrado C,Renes E,García-Avello A

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:The protein deacetylase sirtuin-1 (SIRT1) is an antiaging molecule that is decreased in the lung in patients with COPD. Recently, SIRT1 was reported to be detectable in serum, but serum SIRT1 (s120S) levels have not yet been reported in patients with COPD. METHODS:Serum SIRT1 protein of all samples was meas...

journal_title：Chest

authors： Yanagisawa S,Papaioannou AI,Papaporfyriou A,Baker JR,Vuppusetty C,Loukides S,Barnes PJ,Ito K

更新日期：2017-08-01 00:00:00

abstract：:We studied the correspondence between fluctuations of esophageal pressure measured before and after placement of a nasogastric (NG) tube in six normal volunteers. Flow, airway pressure, and esophageal pressure data from at least 20 breaths were recorded in seven ventilatory conditions in two body postures: 0 degree (s...

journal_title：Chest

authors： Niknam J,Chandra A,Adams AB,Nahum A,Ravenscraft SA,Marini JJ

更新日期：1994-07-01 00:00:00

abstract：:The clinical spectrum of mitochondrial diseases has expanded dramatically in the last decade. Abnormalities of mitochondrial function are now thought to participate in a number of common adult diseases, ranging from exercise intolerance to aging. This review outlines the common presentations of mitochondrial disease i...

journal_title：Chest

authors： Clay AS,Behnia M,Brown KK

更新日期：2001-08-01 00:00:00

abstract：:In a prospective study murmurs increased in intensity with carotid sinus pressure in 18 of 26 patients with hypertrophic obstructive cardiomyopathy (HOCM) (sensitivity, 69.2 percent for the 26 patients, 85.7 percent for the 21 patients in whom heart rate and blood pressure decreased with carotid sinus pressure). On th...

journal_title：Chest

authors： Klein HO,DiSegni E,Dean H,Beker B,Bakst A,Kaplinsky E

更新日期：1988-04-01 00:00:00

abstract：:We describe an elderly patient with an unusual presentation of hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber disease) involving the lung. He had recurrent "pneumonia" caused by massive hemorrhage from endobronchial telangiectases. When stable, he was normoxic, had no evidence of right-to-left shunting, and ...

journal_title：Chest

authors： Lincoln MJ,Shigeoka JW

更新日期：1988-05-01 00:00:00

abstract：:Oxygen therapy is an integral part of the treatment of critically ill patients. Maintenance of adequate oxygen delivery to vital organs often requires the administration of supplemental oxygen, sometimes at high concentrations. Although oxygen therapy is lifesaving, it may be associated with deleterious effects when a...

journal_title：Chest

authors： Budinger GRS,Mutlu GM

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:Cognitive impairment increases with age, as do many serious illnesses requiring intensive care. Little is known, however, about physician recognition of preexisting cognitive impairment in the ICU and which patient factors may play a role in physician recognition. DESIGN:Cross-sectional comparative study. ...

journal_title：Chest

authors： Pisani MA,Redlich C,McNicoll L,Ely EW,Inouye SK

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVES:To review our experience with thoracoscopy and talc poudrage during the previous 15 years with regards to efficacy, side effects, morbidity, and mortality. METHODS:Six hundred fourteen consecutive patients (58.6% female; mean age, 54.5 years) underwent thoracoscopy with talc poudrage from August 1983 to May...

journal_title：Chest

authors： de Campos JR,Vargas FS,de Campos Werebe E,Cardoso P,Teixeira LR,Jatene FB,Light RW

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Correctly staging lung cancer is important because the treatment options and prognosis differ significantly by stage. Several noninvasive imaging studies and invasive tests are available. Understanding the accuracy, advantages, and disadvantages of the available methods for staging non-small cell lung cancer...

journal_title：Chest

authors： Silvestri GA,Gonzalez AV,Jantz MA,Margolis ML,Gould MK,Tanoue LT,Harris LJ,Detterbeck FC

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Low-density gas mixtures and oxygen (O₂) supplementation are known to improve physical performance and ventilatory adaptation during incremental maximal exercise in COPD. We investigated whether their combined use during intense physical training is also effective in ameliorating exercise tolerance in patien...

journal_title：Chest

authors： Scorsone D,Bartolini S,Saporiti R,Braido F,Baroffio M,Pellegrino R,Brusasco V,Crimi E

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2) have been shown to play an important role in transepithelial migration of neutrophil granulocytes during inflammation in various tissues. This study investigated the regulation of gene expression and surface expression of CXCR1 and CXCR2...

journal_title：Chest

authors： Farkas L,Hahn MC,Schmoczer M,Jentsch N,Krätzel K,Pfeifer M,Schulz C

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:There is a growing understanding of the prevalence and impact of psychological disorders on COPD. However, the role of these disorders in early readmission is unclear. METHODS:We analyzed data from 5% fee-for-service Medicare beneficiaries diagnosed with COPD (International Classification of Diseases, Ninth...

journal_title：Chest

authors： Singh G,Zhang W,Kuo YF,Sharma G

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:The "Dutch hypothesis" suggests that asthma and COPD have common genetic determinants. The serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2) gene previously has been associated with COPD. We sought to determine whether SERPINE2 is associated with asthma ...

journal_title：Chest

authors： Himes BE,Klanderman B,Ziniti J,Senter-Sylvia J,Soto-Quiros ME,Avila L,Celedón JC,Lange C,Mariani TJ,Lasky-Su J,Hersh CP,Raby BA,Silverman EK,Weiss ST,DeMeo DL

更新日期：2011-09-01 00:00:00

abstract：:Macrophages are the most abundant immune cell population in normal lung tissue and serve critical roles in innate and adaptive immune responses as well as the development of inflammatory airway disease. Studies in a mouse model of chronic obstructive lung disease and translational studies of humans with asthma and COP...

journal_title：Chest

authors： Byers DE,Holtzman MJ

更新日期：2011-09-01 00:00:00

abstract：:Since publication of the seventh American College of Chest Physicians (ACCP) supplement on antithrombotic and thrombolytic therapy, the results of clinical trials have provided important new information on the management of thromboembolic disorders, and the science of developing recommendations has advanced. In the ac...

journal_title：Chest

authors： Hirsh J,Guyatt G,Albers GW,Harrington R,Schünemann HJ

更新日期：2008-06-01 00:00:00

abstract：:The clinical effect of inhaled radio-labeled (Technetium-99m diethylenetriamine-pentaacetic acid) methacholine was studied in two separate experiments performed in eight symptom-free asthmatics with bronchial hyperresponsiveness. Aerosols were formed by two different nebulizers, producing either mainly small aerosol p...

journal_title：Chest

authors： Schmekel B,Hedenström H,Kämpe M,Lagerstrand L,Stålenheim G,Wollmer P,Hedenstierna G

更新日期：1994-12-01 00:00:00

abstract：:To further delineate indications for noninvasive pressure support ventilation (NIPSV), we proposed this noninvasive technique as an alternative to endotracheal intubation in 17 consecutive patients with acute respiratory failure from various causes. Eight patients (47 percent) were successfully ventilated with NIPSV, ...

journal_title：Chest

authors： Wysocki M,Tric L,Wolff MA,Gertner J,Millet H,Herman B

更新日期：1993-03-01 00:00:00

abstract：:This article discusses the management of venous thromboembolism (VTE) and thrombophilia, as well as the use of antithrombotic agents, during pregnancy and is part of the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Grade 1 recommendations are strong and indicate that ...

journal_title：Chest

authors： Bates SM,Greer IA,Pabinger I,Sofaer S,Hirsh J

更新日期：2008-06-01 00:00:00

abstract：STUDY OBJECTIVES:To assess the effectiveness of pulse oximetry and radioisotope measurement of right-to-left (R-L) shunt for the early detection of pulmonary arteriovenous malformations (PAVMs) in patients with hereditary hemorrhagic telangiectasia (HHT). DESIGN:Patients with HHT had serial measurements of the followi...

journal_title：Chest

authors： Thompson RD,Jackson J,Peters AM,Doré CJ,Hughes JM

更新日期：1999-01-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the long-term clinical course of patients with idiopathic pulmonary fibrosis (IPF) complicated with pulmonary arterial hypertension. DESIGN:Prospective analysis of consecutive IPF patients undergoing initial workup with right-heart catheterization (RHC) and pulmonary function testing (PFT)...

journal_title：Chest

authors： Hamada K,Nagai S,Tanaka S,Handa T,Shigematsu M,Nagao T,Mishima M,Kitaichi M,Izumi T

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To investigate the interrelationship of free radicals (FRs), ischemic preconditioning (IP), and hemodynamic function in coronary artery bypass graft (CABG) patients. DESIGN:Prospective, randomized, and controlled clinical study. PATIENTS:Forty CABG patients were randomized into an IP group (n = 20) and a co...

journal_title：Chest

authors： Wu ZK,Tarkka MR,Eloranta J,Pehkonen E,Kaukinen L,Honkonen EL,Kaukinen S

更新日期：2001-04-01 00:00:00

abstract：STUDY OBJECTIVE:s: Consensus guidelines for the empirical treatment of community-acquired pneumonia (CAP) have been published. We investigated the following factors: (1) the degree of adherence to American Thoracic Society (ATS) and the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) guidelines; and (2) the...

journal_title：Chest

authors： Menéndez R,Ferrando D,Vallés JM,Vallterra J

更新日期：2002-08-01 00:00:00