Cutaneous Manifestations of Granulomatosis with Polyangiitis: A Case Series Study.

Abstract:

:The aim of this study was to determine the prevalence and type of cutaneous manifestations which occur in patients with granulomatosis with polyangiitis and to explore the potential association between cutaneous and systemic involvement in these patients. A retrospective case series study was designed, including all granulomatosis with polyangiitis cases diagnosed between 2010 and 2018 at the Hospital Universitario Virgen de las Nieves. Thirty-nine patients with granulomatosis with polyangiitis were identified, of which 53.85% presented cutaneous manifestations. In decreasing order of frequency, the types of cutaneous problems observed included: palpable purpura, mucocutaneous ulcers, subcutaneous nodules, pyoderma gangrenosum-like ulcers, digital necrosis, papulonecrotic lesions and livedo reticularis. Patients with palpable purpura presented a higher frequency of renal involvement (p = 0.008). Cutaneous manifestations of granulomatosis with polyangiitis may facilitate early disease diagnosis. Likewise, a manifestation such as palpable purpura may be a predictor of kidney damage.

journal_name

Acta Derm Venereol

authors

Montero-Vilchez T,Martinez-Lopez A,Salvador-Rodriguez L,Del Carmen Ramírez-Barberena M,Tercedor-Sanchez J,Molina-Leyva A,Arias-Santiago S

doi

10.2340/00015555-3506

subject

Has Abstract

pub_date

2020-05-28 00:00:00

pages

adv00150

issue

10

eissn

0001-5555

issn

1651-2057

journal_volume

100

pub_type

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