Global coronavirus disease 2019: What has daily cumulative index taught us?

Abstract:

:In addition to the absolute case number, a rapid increase in the number of COVID-19 cases within a short time results in insufficiency of healthcare systems and further negatively affects patient outcomes. This study was conducted to investigate the association between the outcomes of COVID-19 patients and daily cumulative index (DCI), which was defined as the average daily number of new cases of COVID-19 and calculated by cumulative cases/number of days between the first reported case and March 6, 2020, by country. Spearman's rank correlation analyses were conducted to evaluate the relationship between mortality, incidence, and DCI. In this study, DCI was positively correlated with incidence (adjusted risk ratio [aRR] = 1.01, 95% confidence interval [CI] = 1.00-1.02, P < 0.01). Higher correlation was observed between mortality and DCI (mortality rate: r = 0.397, P = 0.018; mortality per 1 000 000 people: r = 0.0.428, P = 0.004) than between disease incidence and DCI. DCI remained statistically significantly associated with mortality per 1 000 000 people after adjustment of Health Care Index (aRR = 1.02, 95% CI = 1.01-1.03, P < 0.001) or Healthcare Access and Quality Index (aRR = 1.02, 95% CI = 1.01-1.04, P < 0.01. Reducing DCI through strict infection control measures can help slow the number of new COVID-19 cases and further improve outcomes in COVID-19 patients.

authors

Lai CC,Wang CY,Wang YH,Hsueh PR

doi

10.1016/j.ijantimicag.2020.106001

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

106001

issue

6

eissn

0924-8579

issn

1872-7913

pii

S0924-8579(20)30159-X

journal_volume

55

pub_type

杂志文章
  • Surveillance of antimicrobial resistance among Escherichia coli in wastewater in Stockholm during 1 year: does it reflect the resistance trends in the society?

    abstract::The resistance patterns of Escherichia coli in untreated (raw) urban wastewater (UW) was monitored by repeated sampling during 1 year. Comparison with data from wastewater samples collected from hospital wastewater (HW) in the same urban area was made. A total of 1326 E. coli isolates from 17 UW samples and 451 isolat...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2014.09.016

    authors: Kwak YK,Colque P,Byfors S,Giske CG,Möllby R,Kühn I

    更新日期:2015-01-01 00:00:00

  • Importance of amino acid alterations and expression of penicillin-binding protein 5 to ampicillin resistance of Enterococcus faecium in Taiwan.

    abstract::The importance of the amino acid sequence in the C-terminal domain of penicillin-binding protein 5 (PBP5) and the levels of PBP5 expression to ampicillin resistance of Taiwan clinical isolates of Enterococcus faecium were studied. Sequence data revealed the existence of 12 amino acid sequence variants within the C-ter...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2006.07.027

    authors: Hsieh SE,Hsu LL,Hsu WH,Chen CY,Chen HJ,Liao CT

    更新日期:2006-12-01 00:00:00

  • Genetic characterisation of drug resistance and clonal dynamics of Acinetobacter baumannii in a hospital setting in Mexico.

    abstract::The aim of this study was to determine the clinical characteristics, molecular epidemiology and biofilm production of Acinetobacter baumannii clinical isolates obtained from a tertiary-care hospital in Mexico. Clinical isolates of A. baumannii (n=152) isolated from 2007 to 2012 were included. Clonal diversity was anal...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2014.10.022

    authors: Bocanegra-Ibarias P,Peña-López C,Camacho-Ortiz A,Llaca-Díaz J,Silva-Sánchez J,Barrios H,Garza-Ramos U,Rodríguez-Flores AM,Garza-González E

    更新日期:2015-03-01 00:00:00

  • Identification and bioevaluation of SRI-12742 as an antimicrobial agent against multidrug-resistant Acinetobacter baumannii.

    abstract::Multidrug-resistant Acinetobacter baumannii (MDR-Ab) is one of the most significant nosocomial pathogens that is being increasingly isolated in healthcare settings worldwide. Owing to its inherent drug-resistant nature, coupled with its ability to readily acquire resistance to other antibiotic classes, there is a real...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2018.02.018

    authors: Shukla M,Soni I,Matsuyama K,Tran T,Tanga M,Gong L,Chopra S

    更新日期:2018-07-01 00:00:00

  • Susceptibility profiles and clinical efficacy of antifungals against candida bloodstream isolates from critically ill patients: Focus on intravenous itraconazole.

    abstract::In vitro and clinical data were analysed to evaluate the susceptibility profile of itraconazole in light of the new cut-off points. The in vitro activity of itraconazole was compared with that of eight comparators against 119 Candida bloodstream isolates from 2015 to 2018. Minimum inhibitory concentrations (MICs) were...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2019.06.019

    authors: Giamarellos-Bourboulis EJ,Stamou A,Maraki S,Solomonidi N,Belesiotou E,Pistiki A,Antoniadou E,Vlachogianni G,Mandragos K,Tasioudis C,Katsenos C,Routsi C,Samonis G,Dimopoulos G

    更新日期:2019-10-01 00:00:00

  • Potentially multidrug-resistant non-fermentative Gram-negative pathogens causing nosocomial pneumonia.

    abstract::Owing to its high morbidity and mortality, nosocomial pneumonia represents a particularly serious illness and one of the most frequent complications in ventilated patients admitted to the Intensive Care Unit. Gram-negative microorganisms, such as Pseudomonas aeruginosa, Acinetobacter baumannii and Stenotrophomonas mal...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijantimicag.2005.11.005

    authors: Ferrara AM

    更新日期:2006-03-01 00:00:00

  • Adverse events of fluoroquinolones vs. other antimicrobials prescribed in primary care: A systematic review and meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:Fluoroquinolones (FQs) are second-line antimicrobial agents. Once the decision to prescribe an antimicrobial is made, the choice of antimicrobial should be based on both the benefits and adverse effects. This systematic review quantifies the occurrence of common adverse events (AEs) related to FQs in relatio...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.ijantimicag.2018.04.014

    authors: Tandan M,Cormican M,Vellinga A

    更新日期:2018-11-01 00:00:00

  • Effect of sodium diclofenac on the bioavailability of amoxicillin.

    abstract::The aim of this study was to evaluate the effect of sodium diclofenac on the bioavailability of amoxicillin. In this randomised, crossover study with a 1-week washout period, 20 volunteers received a 2g oral dose of amoxicillin (Amoxil) (Group 1) or a 2g oral dose of amoxicillin with 100 mg of sodium diclofenac (Volta...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ijantimicag.2006.02.005

    authors: de Cássia Bergamaschi C,Motta RH,Franco GC,Cogo K,Montan MF,Ambrosano GM,Rosalen PL,Del Fiol Fde S,Groppo FC

    更新日期:2006-05-01 00:00:00

  • Screening for anti-HIV drugs that can combine virucidal and virustatic activities synergistically.

    abstract::Chlorcyclizine HCl and ciprofloxacin HCl were shown to have anti-HIV activity. They possess virustatic and virucidal activities against HIV, a murine retrovirus (RV) and several other RNA and DNA viruses. These drugs were screened from a large number of compounds on the basis of in vitro mutagenicity and antimetabolit...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(99)00158-2

    authors: Chakrabarty AN,Mookerjee M,Dastidar SG

    更新日期:2000-04-01 00:00:00

  • Multicentre study of risk factors for mortality in patients with Acinetobacter bacteraemia receiving colistin treatment.

    abstract::Colistin remains a last-line antibiotic for the treatment of infections by multidrug-resistant Acinetobacter species. However, mortality rates are high in patients with Acinetobacter infection receiving colistin treatment. This multicentre study evaluated whether colistin susceptibility, additional antimicrobial agent...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2020.105956

    authors: Lee YT,Sun JR,Wang YC,Chiu CH,Kuo SC,Chen TL,ACTION Study Group.,Yang YS

    更新日期:2020-06-01 00:00:00

  • Voriconazole brain tissue levels in rhinocerebral aspergillosis in a successfully treated young woman.

    abstract::Invasive aspergillosis of the central nervous system has a mortality rate exceeding 90%. We describe a 29-year-old woman with a medical history of chronic polyarthritis who developed a proven rhinocerebral Aspergillus fumigatus infection refractory to first-line treatment with liposomal amphotericin B. The patient res...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2006.04.006

    authors: Elter T,Sieniawski M,Gossmann A,Wickenhauser C,Schröder U,Seifert H,Kuchta J,Burhenne J,Riedel KD,Fätkenheuer G,Cornely OA

    更新日期:2006-09-01 00:00:00

  • Uncommon Detection of Mixed HCV Genotype Infections in Recently Infected Men Who Have Sex with Men.

    abstract:INTRODUCTION:Mixed hepatitis C virus (HCV) genotype (GT) infections are clinically important as different genotypes have varied sensitivities to direct-acting antivirals (DAAs). A high prevalence of mixed GT infections was observed in individuals who inject drugs and had multiple HCV exposures. The prevalence of mixed ...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2019.06.001

    authors: Nguyen T,Delaugerre C,Valantin MA,Amiel C,Netzer E,L'Yavanc T,Ohayon M,Israel G,Valin N,Day N,Kreplak G,Pialoux G,Calvez V,Molina JM,Marcelin AG,Todesco E

    更新日期:2019-10-01 00:00:00

  • Very prolonged liposomal amphotericin B use leading to a lysosomal storage disease.

    abstract::Amphotericin B is a powerful polyene antifungal drug used for treating systemic fungal infections and is usually administered for a short period. Side effects after prolonged use are unknown in humans. Here we report the case of a 28-year-old man suffering from chronic granulomatous disease (CGD), treated for invasive...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2014.02.015

    authors: Michot JM,Gubavu C,Fourn E,Maigne G,Teicher E,Angoulvant A,Blanche S,Lortholary O,Coilly A,Duclos-Vallée JC,Sebagh M,Guettier C,Aumont C,Delfraissy JF,Lambotte O

    更新日期:2014-06-01 00:00:00

  • Clinical aspects and cost of invasive Streptococcus pneumoniae infections in children: resistant vs. susceptible strains.

    abstract::Invasive Streptococcus pneumoniae infections in children are associated with serious consequences in terms of morbidity and mortality. The main objective of the study was to determine if invasive infections caused by penicillin-resistant Streptococcus pneumoniae (PRSP) differed in clinical presentation, outcome, risk ...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(02)00127-9

    authors: Quach C,Weiss K,Moore D,Rubin E,McGeer A,Low DE

    更新日期:2002-08-01 00:00:00

  • Pentamidine inhibits Coxiella burnetii growth and 23S rRNA intron splicing in vitro.

    abstract::Coxiella burnetii is the bacterial agent of Q fever in humans. Acute Q fever generally manifests as a flu-like illness and is typically self-resolving. In contrast, chronic Q fever usually presents with endocarditis and is often life-threatening without appropriate antimicrobial therapy. Unfortunately, available optio...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2010.05.017

    authors: Minnick MF,Hicks LD,Battisti JM,Raghavan R

    更新日期:2010-10-01 00:00:00

  • Lipid-based amphotericin B: a review of the last 10 years of use.

    abstract::The last decade has been remarkable for the dramatic increase in the prevalence of serious fungal infections in patients with haematological disorders and neutropenic cancer patients. The mortality rate of deep-seated infection has been in excess of 90% and there is no doubt that this is one of the greatest challenges...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/s0924-8579(00)00341-1

    authors: Hann IM,Prentice HG

    更新日期:2001-03-01 00:00:00

  • ABC-transporters: implications on drug resistance from microorganisms to human cancers.

    abstract::Resistance to chemotherapy is a common clinical problem in patients with infectious diseases as well as in patients with cancer. During treatment of infections or malignant tumors, the drug targets of prokaryotic or eukaryotic microorganisms and neoplastic cells are often found to be refractory to a variety of drugs t...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/s0924-8579(03)00203-6

    authors: Lage H

    更新日期:2003-09-01 00:00:00

  • Chlorhexidine exposure of clinical Klebsiella pneumoniae strains leads to acquired resistance to this disinfectant and to colistin.

    abstract::Chlorhexidine is widely used as a disinfectant in hospitals, which may impose a selective pressure on bacteria. This study aimed to determine whether continuous exposure to chlorhexidine could lead to adaptive resistance and cross-resistance as well as investigating potential resistance mechanisms. Three clinical Kleb...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2019.02.012

    authors: Zhang Y,Zhao Y,Xu C,Zhang X,Li J,Dong G,Cao J,Zhou T

    更新日期:2019-06-01 00:00:00

  • Antiviral therapy of herpes simplex.

    abstract::Herpes simplex virus (HSV) infections in immunocompromised patients are more severe and invasive than in non-immunocompromised patients. They are characterised by prolonged viral shedding and a tendency to heal more slowly. In addition, resistant viruses are exclusively isolated in immunocompromised patients, requirin...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/s0924-8579(00)00233-8

    authors: Snoeck R

    更新日期:2000-10-01 00:00:00

  • Antibiotic resistance: the perfect storm.

    abstract::The worldwide epidemic of antibiotic resistance is in danger of ending the golden age of antibiotic therapy. Resistance impacts on all areas of medicine, and is making successful empirical therapy much more difficult to achieve. Antibiotic choices are often severely restricted, and the pipeline of new antibiotics is a...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/S0924-8579(09)70549-7

    authors: Gould IM

    更新日期:2009-08-01 00:00:00

  • Ventilator-associated pneumonia.

    abstract::Mechanically ventilated patients are at a substantially higher risk for developing nosocomial pneumonia. Overall, there is a relatively constant 1&!TN!150;3% risk per day of developing pneumonia while receiving mechanical ventilation. The sensitivity and specificity of clinical criteria alone for diagnosis of ventilat...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(98)00037-5

    authors: Visnegarwala F,Iyer NG,Hamill RJ

    更新日期:1998-08-01 00:00:00

  • In vitro anti-trichomonad effectiveness of a gossypol-metronidazol blend.

    abstract::With the aid of the Basic Sequential Analytical Simplex Method the in vitro anti-trichomonad effectiveness of several metronidazole/gossypol blends was determined. While the combination that produced 50% of growth inhibition on trichomonad cultures (IC50) contained 15.1 microM gossypol and 0.087 microM metronidazole, ...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(97)00026-5

    authors: Teresa González-Garza M,Said-Fernández S

    更新日期:1997-06-01 00:00:00

  • In vitro activity of four fluoroquinolones against clinical isolates of Pseudomonas aeruginosa determined by the E test.

    abstract::Ciprofloxacin, levofloxacin, ofloxacin, and trovafloxacin were tested by the E-test against 100 clinical isolates of Pseudomonas aeruginosa. Ciprofloxacin was the most active of the tested agents with 82% of isolates having a MIC 8). Levofloxacin and trovafloxacin had nearly identical potency:...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(00)00132-1

    authors: Swiatlo E,Moore E,Watt J,McDaniel LS

    更新日期:2000-06-01 00:00:00

  • Tuberculosis in patients with systemic rheumatic or pulmonary diseases treated with glucocorticosteroids and the preventive role of isoniazid: a review of the available evidence.

    abstract::Development of tuberculosis (TB) is a concern in patients who receive glucocorticosteroids for the treatment of chronic rheumatic or pulmonary diseases. However, the incidence of development of TB in such patients and the prophylactic role of isoniazid (INH) are unclear. We evaluated the available evidence from 20 rel...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijantimicag.2007.07.010

    authors: Falagas ME,Voidonikola PT,Angelousi AG

    更新日期:2007-12-01 00:00:00

  • Bacterial strain-independent AUC/MIC and strain-specific dose-response relationships reflecting comparative fluoroquinolone anti-pseudomonal pharmacodynamics in an in vitro dynamic model.

    abstract::To compare the antimicrobial effects (AMEs) of two quinolones in terms of the AUC/MIC- and dose (D)-response relationships, five differentially susceptible clinical isolates of Pseudomonas aeruginosa were exposed to decreasing concentrations of ciprofloxacin (two 12-h doses with T(1/2) = 4 h) and trovafloxacin (a sing...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(02)00116-4

    authors: Lubenko IY,Vostrov SN,Portnoy YA,Zinner SH,Firsov AA

    更新日期:2002-07-01 00:00:00

  • Pattern of SARS-CoV-2 infection among dependant elderly residents living in long-term care facilities in Marseille, France, March-June 2020.

    abstract:OBJECTIVES:This study aimed to report the results of SARS-CoV-2 PCR-based screening campaigns conducted on dependent elderly residents (compared with staff members) in long-term care facilities (LTCFs) in Marseille, France, and the follow-up of positive cases. METHODS:Data from 1691 elderly residents and 1000 members ...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2020.106219

    authors: Ly TDA,Zanini D,Laforge V,Arlotto S,Gentile S,Mendizabal H,Finaud M,Morel D,Quenette O,Malfuson-Clot-Faybesse P,Midejean A,Le-Dinh P,Daher G,Labarriere B,Morel-Roux AM,Coquet A,Augier P,Parola P,Chabriere E,Raoult D

    更新日期:2020-12-01 00:00:00

  • Evaluation of the safety of macrolides.

    abstract::The safety of all drugs is established by animal studies, administration to healthy volunteers and the observations during clinical studies to confirm efficacy. During these studies, patients are questioned about side-effects and extensive laboratory testing of blood and urine samples is performed. Despite these exten...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/s0924-8579(01)00399-5

    authors: Williams JD

    更新日期:2001-01-01 00:00:00

  • Phenothiazinium-fluoroquinolone drug conjugates.

    abstract::Synthesis and antibacterial screening of a homologous series of 3-dialkylaminophenothiazinium-7-norfloxacin conjugates was carried out alongside a corresponding series of symmetrical methylene blue derivatives. The norfloxacin conjugates maintained typical methylene blue derivative photoproperties, such as long wavele...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2009.11.022

    authors: Wainwright M,Shah A,Meegan K,Loughran C,Smith A,Valli N,Dempster N

    更新日期:2010-04-01 00:00:00

  • Comparative in vitro activity of gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin and trovafloxacin against 4151 Gram-negative and Gram-positive organisms.

    abstract::Gatifloxacin, grepafloxacin, moxifloxacin and trovafloxacin are fluoroquinolones with enhanced Gram-positive activity while retaining broad-spectrum activity against Gram-negative pathogens. Levofloxacin and ciprofloxacin are older quinolones with broad activity against Gram-negative pathogens and borderline activity ...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(99)00143-0

    authors: Blondeau JM,Laskowski R,Bjarnason J,Stewart C

    更新日期:2000-02-01 00:00:00

  • In-vitro development of an effective treatment for Acanthamoeba keratitis.

    abstract::The aim of this study was to develop an in-vitro topical treatment for Acanthamoeba keratitis (AK) effective against cysts and trophozoites. Qualitative assays were performed with voriconazole, chlorhexidine, propamidine, cellulase, tobramycin, ciprofloxacin and paromomycin as monotherapy and various combinations. Rib...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2017.03.033

    authors: Ortillés Á,Belloc J,Rubio E,Fernández MT,Benito M,Cristóbal JÁ,Calvo B,Goñi P

    更新日期:2017-09-01 00:00:00