Abstract:
:Exposure to metal-contaminated water has been shown to result in a number of reproductive abnormalities in adult and larvae fish, such as failure of oocyte maturation and teratogenic effects. Recently, dietary uptake of metals by fish has been recognized as a critical route of exposure, however, the mechanisms of metal uptake and toxicity are poorly understood and in need of further investigation. The objectives of the present study are to quantify uranium (U dietary transfers from spiked artificial diets) in Danio rerio tissues and embryos, as well as establish its effect on reproduction and embryonic development. Uranium's environmental prominence is currently increasing because of new mining and milling activities. Uranium concentrations range from 0.02 µg/L in natural waters to 2 mg/L. The focus of this study was to examine the trophic transfer and effects of U following exposure modalities (dose, exposure duration 1 to 20 d). Two different isotopes were used to distinguish between chemical and radioactivity toxicity of U. Results showed that U trophic transfer was low (0.52%). Uranium tissue distributions showed that accumulation occurred in digestive organs (liver, digestive tract) following dietary exposure. High levels of U were measured in the gonads (female in particular, >20% of relative burden). High U accumulation levels in eggs indicated maternal transfer of the contaminant. Moreover, U trophic exposure led to a reduction in reproduction success as a function of U accumulated levels. High U exposure conditions strongly reduced the total number of eggs (50%) and their viability at 10 d (reduction of the clutch number, low quality of eggs).
journal_name
Environ Toxicol Chemjournal_title
Environmental toxicology and chemistryauthors
Simon O,Mottin E,Geffroy B,Hinton Tdoi
10.1002/etc.381subject
Has Abstractpub_date
2011-01-01 00:00:00pages
220-5issue
1eissn
0730-7268issn
1552-8618journal_volume
30pub_type
杂志文章abstract::The use of aqueous film-forming foam (AFFF) has resulted in the widespread occurrence of per- and polyfluoroalkyl substances (PFAS) in groundwater, drinking water, soils, sediments, and receiving waters throughout the United States and other countries. We present the research and development efforts to date by the Str...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4894
更新日期:2021-01-01 00:00:00
abstract::The determination of site-specific water quality criteria generally involves the recalculation of national criteria using laboratory-derived toxicity data or the conducting of bioassays using site water. Because of uncertainty of predictions of in-stream biological responses to contamination, an alternative procedure ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.5620050501
更新日期:1986-05-01 00:00:00
abstract::This study presents concurrently sampled ambient air data for a range of polycyclic aromatic hydrocarbons (PAHs) and polychlorinated naphthalenes (PCNs) at the continental scale. This was achieved with a passive air sampling system, by deploying polyurethane foam disks, which were prepared in one laboratory, sealed to...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-420
更新日期:2004-06-01 00:00:00
abstract::The present study investigated the impact of nano titanium dioxide (nTiO(2) ) exposure on the cellular structures of the nitrogen-fixing cyanobacteria Anabaena variabilis. Results of the present study showed that nTiO(2) exposure led to observable alteration in various intracellular structures and induced a series of ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.445
更新日期:2011-04-01 00:00:00
abstract::Lanthanide emissions to the environment increase as a result of the growing industrial applications of these elements. However, robust data to evaluate the environmental fate of lanthanides are scarce. This article describes the accumulation and elimination of lanthanum (La) by common duckweed (Lemna minor L.). Specia...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2002-07-01 00:00:00
abstract::Non-anadromous forms of Arctic char (Salvelinus alpinus), those that are restricted to lakes and rivers, typically have higher mercury (Hg) concentrations than anadromous forms, which migrate to and from the sea. Using tissue burden data from the literature and our own analyses, we performed a screening-level risk ass...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4341
更新日期:2019-03-01 00:00:00
abstract::Developing and validating quantitative cationic-activity relationships or (Q)CARs to predict the toxicity metals is challenging because of issues associated with metal speciation, complexation and interactions within biological systems and the media used to study these interactions. However, a number of simplifying as...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章,评审
doi:10.1897/02-568
更新日期:2003-08-01 00:00:00
abstract::Continuous subchronic exposure experiments were conducted to assess the effects of diazinon, an organophosphate pesticide, on the survival, growth and activity of larvae of the Asian common toad Bufo melanostictus. Two larval stages, the gill stage (Gosner stages 21 and 22) and gill-atrophy stage (Gosner stages 24 and...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/07-315.1
更新日期:2008-11-01 00:00:00
abstract::A Unit World approach has been used extensively to rank chemicals for their hazards and to understand differences in chemical behavior. Whereas the fate and effects of an organic chemical in a Unit World Model (UWM) analysis vary systematically according to one variable (fraction of organic carbon), and the chemicals ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.606
更新日期:2011-09-01 00:00:00
abstract::Most toxicity tests investigate constant concentrations of a chemical. Concentrations of many compounds in the environment are dynamic, however, and individuals may be more sensitive to pulses of a chemical initiated at specific points during development. Realistic toxicity tests are important to accurately assess the...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/08-325.1
更新日期:2009-06-01 00:00:00
abstract::Monte Carlo simulations were used to evaluate statistical methods for estimating 95% upper confidence limits of mean constituent concentrations for left-censored data with nonuniform detection limits. Two primary scenarios were evaluated: data sets with 15 to 50% nondetected samples and data sets with 51 to 80% nondet...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-548r.1
更新日期:2006-09-01 00:00:00
abstract::Field-related influences on polychlorinated biphenyl (PCB) exposure were evaluated by employing caged deposit-feeders, Neanthes arenaceodentata, along with polyoxymethylene (POM) samplers using parallel in situ and ex situ bioassays with homogenized untreated or activated carbon (AC) amended sediment. The AC amendment...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.367
更新日期:2011-01-01 00:00:00
abstract::The 2 most abundant polycyclic aromatic hydrocarbons (PAHs) measured in Deepwater Horizon crude oil, naphthalene and phenanthrene, and their associated homologs have both been shown to be acutely toxic in fish. Although fish have a relatively high metabolic capacity for PAHs, hydroxylated PAH (OH-PAH) derivatives form...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3898
更新日期:2017-11-01 00:00:00
abstract::Standard U.S. Environmental Protection Agency (U.S. EPA) statistical analyses of whole effluent toxicity tests involve the estimation of the concentration associated with a specified level of inhibition relative to control responses. Current U.S. EPA estimation methods (linear interpolation or probit-based methods) ar...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract::This study investigates both the methods and the multispecies and functional level effects of a release of a complex hydrocarbon mixture from sediments using a 60-d modified mixed flask culture (MFC) microcosm. Neat Jet-A was injected and mixed into the sediment with one nondosed and three dosed concentrations. Univar...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract::Retinoids are known to regulate important processes such as differentiation, development, and embryogenesis. Some effects, such as malformations in frogs or changes in metabolism of birds, could be related to disruption of the retinoid signaling pathway by exposure to organic contaminants. A new reporter gene assay ha...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/06-513r.1
更新日期:2007-08-01 00:00:00
abstract::To gain new insight into the mechanism of selective cytotoxicity of benzoylureas as insecticides, the in vitro mode of action of chlorfluazuron was investigated on lepidopteran Tn5B1-4 and Sf-21 cells and human Hek293 and HepG2 cells. Chlorfluazuron inhibited the proliferation of Tn5B1-4 and Sf-21 cells with 50% inhib...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2969
更新日期:2015-07-01 00:00:00
abstract::Estuarine fish in the northern Gulf of Mexico are exposed annually to hypoxic conditions. In addition to hypoxia, fish located throughout the northern Gulf of Mexico were potentially exposed to oil released during the Deepwater Horizon incident. Therefore, the interaction between oil exposure and hypoxia is worth inve...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3207
更新日期:2016-03-01 00:00:00
abstract::Ecological soil-screening levels (Eco-SSLs) were developed by the United States Environmental Protection Agency (USEPA) for the purposes of setting conservative soil screening values that can be used to eliminate the need for further ecological assessment for specific analytes at a given site. Ecological soil-screenin...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2675
更新日期:2014-10-01 00:00:00
abstract::In plant tissues, xenobiotics often are conjugated with natural constituents such as sugars, amino acids, glutathione, and malonic acid. Usually, conjugation processes result in a decrease in the reactivity and toxicity of xenobiotics by increasing the water solubility and polarity of conjugates, and reducing their mo...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/07-036R.1
更新日期:2007-11-01 00:00:00
abstract::The effect of sodium chloride (NaCl) on cadmium (Cd) uptake, translocation, and oxidative stress was investigated using 2 tobacco cultivars differing in Cd tolerance. The growth inhibition of the tobacco plants exposed to Cd toxicity was in part alleviated by moderate addition of NaCl in the culture solution. Cadmium ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2183
更新日期:2013-06-01 00:00:00
abstract::Silver nanoparticles (AgNP) are now widely used as antibacterial products, and their potential toxicities in aquatic organisms are a matter of increasing concern. In the present study, we conducted experiments to reveal the acute and chronic toxicities of AgNP and its bioaccumulation from both aqueous and dietary sour...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.451
更新日期:2011-04-01 00:00:00
abstract::Use of solid-phase microextraction (SPME) fibers as a dose metric for toxicity testing was evaluated for hydrophobic pesticides to the midge Chironomus dilutus and the amphipod Hyalella azteca. Test compounds included p,p'-dichlorodiphenyltrichloroethane (p,p'-DDT), p,p'-dichlorodiphenyldichloroethane (p,p'-DDD), p,p'...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.1935
更新日期:2012-09-01 00:00:00
abstract::An experimental study was carried out to investigate direct and direct plus trophic contamination routes of the crayfish Astacus astacus by inorganic mercury (Hg(II)) or methylmercury (MeHg). Direct exposure was based on low contamination conditions, 300 and 30 ng/L in the dissolved phase, respectively, during 30 d at...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract::A theoretical analysis was performed to examine the role of naphthalene dioxygenase (NDO) enzymes in determining differences in biodegradability and biodegradation rates of two- to four-ring polycyclic aromatic hydrocarbons (PAHs) via oxygenation and desaturation reactions. Investigation of the thermodynamics of PAH b...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-311r.1
更新日期:2006-04-01 00:00:00
abstract::We propose a biologically based approach to analyze reproductive data for the midge (Chironomus riparius). We showed in a previous study that its larval development can be divided in two distinct phases regarding the use of energy: The somatic growth period and the gametic growth period. We hypothesize here the gameti...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-52
更新日期:2004-01-01 00:00:00
abstract::Silver nanoparticles (AgNPs) from industrial use, discharged via the land application of sewage sludge, are interacting with soil biota, including earthworms. In affected organisms, excessive production of reactive oxygen species can result in lipid peroxidation, shifting the balance between oxidants and antioxidants ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4713
更新日期:2020-05-01 00:00:00
abstract::Diluted bitumen (dilbit; the product of oil sands extraction) is transported through freshwater ecosystems critical to Pacific salmon. This is concerning, because crude oil disrupts cardiac development, morphology, and function in embryonic fish, and cardiac impairment in salmon can have major consequences on migrator...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3533
更新日期:2017-02-01 00:00:00
abstract::A market for bisphenol A (BPA) replacement compounds has emerged due to restrictions on the use of BPA. Some of these compounds were detected in the environment, yet little is known about their toxicological properties. In the present study, an avian in vitro toxicogenomic approach was used to compare the effects of f...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4985
更新日期:2021-01-19 00:00:00
abstract::The major toxaphene metabolites in sediment and soils (2-exo,3-endo,6-exo,8,9,10-hexachlorobornane [B6-923] and 2-endo,3-exo,5-endo,6-exo,8,9,10-heptachlorobornane [B7-1001]) were incubated with the isolated gram-negative bacterium Dehalospirillum multivorans. Within 14 d, biotransformation of B7-1001 was nearly quant...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-221
更新日期:2004-03-01 00:00:00