Burkholderia pseudomallei was Identified in a Melioidosis Aneurysm using Polymerase Chain Reaction Targeting 23S rRNA.

Abstract:

:Melioidosis abdominal aortic aneurysm and splenic abscesses lead to poor prognosis and high mortality rate as high as 50% due to delayed/missed diagnosis. We describe an attempt to identify Burkholderia pseudomallei immediately, which was confirmed by polymerase chain reaction (PCR) and gene sequence analysis of 23S rRNA gene. PCR is not only an unambiguous identification of B. pseudomallei but also a rapid detection because B. pseudomallei may not be readily isolated. For patients of melioidosis abdominal aortic aneurysm with spleen abscess, prolonged antibiotic therapy, splenectomy and artificial vessel replacement provided an excellent result in our study. The progression, roentgenographic findings and histopathology character of melioidosis are similar to those of tuberculosis disease. PCR is useful to differentiate B. pseudomallei from Mycobacterium tuberculosis.

journal_name

Ann Vasc Surg

authors

Shi L,Chen J,Yi G

doi

10.1016/j.avsg.2020.04.035

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

569.e13-569.e20

eissn

0890-5096

issn

1615-5947

pii

S0890-5096(20)30354-X

journal_volume

68

pub_type

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    更新日期:2021-01-05 00:00:00

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    pub_type: 杂志文章

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    更新日期:2014-10-01 00:00:00

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    更新日期:2014-07-01 00:00:00