Global Health and Surgical Infection: From Neglect to Emerging Frontier.

Abstract:

: Background: In past decades, surgical site infections (SSIs) were neglected and not given much global attention in low- and middle-income countries (LMICs). The risk and incidence of SSIs in LMICs continue to increase. Methods: We reviewed the limited quality data on SSIs and complicated intra-abdominal infections in these settings that have hampered advocacy and infection prevention and control efforts. Results: This review identifies the rising profile of global surgery that has resulted in efforts to scale up access to surgical care as well as increase surgical volumes to address unmet needs. The fallout of these efforts would be increasing SSI rates and a rising volume of laparotomies for intra-abdominal infections. Conclusion: Surgical infections are an emerging frontier in global health and surgery. There is an urgent need for global advocacy and investments in their prevention and control.

journal_name

Surg Infect (Larchmt)

journal_title

Surgical infections

authors

Seyi-Olajide JO,Ameh EA

doi

10.1089/sur.2020.006

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

516-522

issue

6

eissn

1096-2964

issn

1557-8674

journal_volume

21

pub_type

杂志文章
  • Contemporary predictors of conversion from laparoscopic to open appendectomy.

    abstract:BACKGROUND:We defined the contemporary conversion rate from laparoscopic appendectomy (LA) to open appendectomy and identified pre-operative factors associated with conversion. METHODS:Retrospective review of 941 consecutive LAs performed for suspected acute appendicitis in a single urban university hospital between 2...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2010.079

    authors: Wagner PL,Eachempati SR,Aronova A,Hydo LJ,Pieracci FM,Bartholdi M,Umunna BP,Shou J,Barie PS

    更新日期:2011-08-01 00:00:00

  • Treating Surgical Infections in Low- and Middle-Income Countries: Source Control, Then What?

    abstract::Surgical infections present a significant burden of disease globally. Management focuses on source control and appropriate antibiotic therapy. This remains a challenge in low- and middle-income settings, where access to surgical care and antibiotics is limited. This paper discusses the complex challenges facing the ma...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2018.125

    authors: Rickard J

    更新日期:2019-04-01 00:00:00

  • Validation of a Predictive Scoring System for Deep Sternal Wound Infection after Bilateral Internal Thoracic Artery Grafting in a Cohort of French Patients.

    abstract:BACKGROUND:The Gatti score is a weighted scoring system based on risk factors for deep sternal wound infection (DSWI) that was created in an Italian center to predict DSWI risk after bilateral internal thoracic artery (BITA) grafting. No external evaluation based on validation samples derived from other surgical center...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2016.150

    authors: Perrotti A,Gatti G,Dorigo E,Sinagra G,Pappalardo A,Chocron S

    更新日期:2017-02-01 00:00:00

  • Emergence of resistant microbes in critical care units is transient, despite an unrestricted formulary and multiple antibiotic trials.

    abstract:BACKGROUND:Antimicrobial resistance is a growing problem in the intensive care setting. This study was designed to evaluate the trends in bacterial prevalence and changes in antibiotic resistance at a large university hospital over the past decade. Antimicrobial resistance data were compared among the surgical intensiv...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/109629602760105808

    authors: Franklin GA,Moore KB,Snyder JW,Polk HC Jr,Cheadle WG

    更新日期:2002-07-01 00:00:00

  • Open fractures: it doesn't come out in the wash.

    abstract:BACKGROUND:Six hours from injury to washout is considered the gold standard in the treatment of open traumatic fractures. Despite this being our hospital policy, the rural nature of our Level I trauma center causes delays in discovery and transport, creating a unique randomization of time to washout. We hypothesized th...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2010.075

    authors: Schlitzkus LL,Goettler CE,Waibel BH,Sagraves SG,Hasty CC,Edwards M,Rotondo MF

    更新日期:2011-10-01 00:00:00

  • History of Urinary Retention Is a Risk Factor for Infection after Prostate Biopsy: A Nationwide, Population-Based Cohort Study.

    abstract:BACKGROUND AND AIM:Infection or bleeding after transrectal prostate biopsy remains a concern of both patients and urologists. We explored the risk of association of certain co-morbidities with both complications. PATIENTS AND METHODS:Using the Taiwan National Health Insurance Research Database, we identified patients ...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2018.174

    authors: Lin SL,Lin CT,Huang WT,Jou YC,Tzai TS,Tsai YS

    更新日期:2019-04-01 00:00:00

  • Nucleated red blood cells are associated with a higher mortality rate in patients with surgical sepsis.

    abstract:BACKGROUND:Nucleated red blood cells (NRBCs) are present in certain non-oncologic disease states and are associated with a poor prognosis. The purpose of this study was to evaluate NRBCs as an early prognostic marker for death in patients with surgical sepsis. METHODS:Retrospective evaluation of data collected prospec...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2011.089

    authors: Desai S,Jones SL,Turner KL,Hall J,Moore LJ

    更新日期:2012-12-01 00:00:00

  • Effectiveness of pre-operative cefazolin in obese patients.

    abstract:BACKGROUND:Cefazolin remains the preferred preoperative antibiotic for the majority of surgical procedures. However, outcome evidence supporting current dosing recommendations for pre-operative prophylaxis is scarce, particularly for obese patients. With more than 33% of adults in the United States classified as obese,...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2012.167

    authors: Unger NR,Stein BJ

    更新日期:2014-08-01 00:00:00

  • Clinical and economic consequences of post-operative infections following major elective surgery in U.S. hospitals.

    abstract:BACKGROUND:The incidence and consequences of post-operative infections in patients undergoing major elective surgery is not well understood. METHODS:Using a large U.S. healthcare claims database, we identified all patients who underwent major elective surgery between January 1, 2007, and December 31, 2009. For each su...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2012.200

    authors: Berger A,Edelsberg J,Yu H,Oster G

    更新日期:2014-06-01 00:00:00

  • Characteristics and Outcome of Twenty-Nine Implant-Related Infections of the Hand and Fingers: Results from a Twelve-Year Observational Study.

    abstract:BACKGROUND:Implant-related infections in hand surgery are dreaded complications, potentially leading to loss of finger joint function or amputation. Knowledge about the clinical presentation and treatment concepts of these infections is limited. The aim of this study is to present a consecutive series of patients with ...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2018.133

    authors: Meier R,Wirth T,Vögelin E,Sendi P

    更新日期:2018-10-01 00:00:00

  • Percutaneous versus open tracheostomy: comparison of procedures and surgical site infections.

    abstract:BACKGROUND:Tracheostomy is one of the most common procedures performed in trauma patients in the intensive care unit (ICU). Few studies have evaluated the incidence of surgical site infections (SSIs) specifically in a trauma population. Our objective was to compare the incidence of SSI after open versus percutaneous tr...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2011.059

    authors: Park H,Kent J,Joshi M,Zhu S,Bochicchio GV,Henry S,Scalea T

    更新日期:2013-02-01 00:00:00

  • Post-appendectomy surgical site infection rate after using an antimicrobial film incise drape: a prospective study.

    abstract:BACKGROUND:An appendectomy is a contaminated or potentially dirty surgical procedure that can be associated with surgical site infection (SSI). METHODS:A single-center unblinded prospective cohort study examined the role of antimicrobial incise film drapes in lowering the rate of SSI after appendectomy. Any patient ag...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2013.188

    authors: Al-Qahtani SM,Al-Amoudi HM,Al-Jehani S,Ashour AS,Abd-Hammad MR,Tawfik OR,Baslaim MM,Farrokhyar F

    更新日期:2015-04-01 00:00:00

  • Awareness of Practice and Comparison with Best Evidence in Surgical Site Infection Prevention in Colorectal Surgery.

    abstract:: Background: The use of mechanical bowel preparation and prophylaxis with oral antimicrobial agents can prevent surgical site infection (SSI) in colorectal surgical procedures, but routine adoption of these and other practices by surgeons has been limited. The aim of this s...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2019.203

    authors: Badia JM,Casey AL,Rubio-Pérez I,Arroyo-García N,Espin E,Biondo S,Balibrea JM

    更新日期:2020-04-01 00:00:00

  • Temporary Intra-Operative Portocaval Shunts, Post-Operative Infections, and Mid-Term Survival after Cava-Sparing Liver Transplantation.

    abstract:BACKGROUND:Temporary intra-operative portocaval shunts (TPCS) are believed to improve outcomes after cava-sparing liver transplantation. We hypothesize that decompression of the portal venous system via a TPCS reduces gut congestion, thereby decreasing bacterial translocation. Thus, we sought to clarify whether transpl...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2017.036

    authors: Weniger M,Andrassy J,Weig T,Grabein B,Crispin A,Rentsch M,Siebers C,Bazhin A,D'Haese JG,Hartwig W,Werner J,Guba M,Faist E,Pratschke S,Angele MK

    更新日期:2017-10-01 00:00:00

  • Perioperative management of patients undergoing elective colorectal surgery in Israel: a national survey.

    abstract:BACKGROUND:The approach to perioperative antibiotic prophylaxis, bowel preparation, and postoperative routines in elective colorectal resections has changed over the last two decades. The aim of this national survey was to document the current methods of perioperative management of those patients scheduled for elective...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2005.6.305

    authors: Shpitz B,Reissman P,Rabau M,Ziv Y

    更新日期:2005-10-01 00:00:00

  • Pyomyositis: Are We Missing the Diagnosis?

    abstract:BACKGROUND:Pyomyositis (PY) is a primary infection of the skeletal muscles, leading to inflammation of the muscle fibers followed by pus formation and even necrosis in late stages. Because of overlap in presentation of intermuscular abscess (IM) and PY, the exact incidence and severity of PY is under-appreciated. PATI...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2015.191

    authors: Agarwal N,Aroor S,Saini P,Gupta A,Kaur N

    更新日期:2016-10-01 00:00:00

  • Pre-hospital intubation factors and pneumonia in trauma patients.

    abstract:BACKGROUND:We reported similar rates of ventilator-associated pneumonia (VAP) previously in trauma patients intubated either in a pre-hospital (PH) venue or the emergency department. A subset of PH intubations with continuous quality assessment was re-examined to identify the intubation factors associated with VAP. ME...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2010.074

    authors: Evans HL,Warner K,Bulger EM,Sharar SR,Maier RV,Cuschieri J

    更新日期:2011-10-01 00:00:00

  • Antimicrobial Activity of Ceftaroline Tested against Staphylococcus aureus from Surgical Skin and Skin Structure Infections in US Medical Centers.

    abstract:BACKGROUND:Ceftaroline fosamil is a novel cephalosporin approved by the United States Food and Drug Administration (US FDA) for treatment of acute bacterial skin and skin structure infection, including those caused by methicillin-resistant Staphylococcus aureus (MRSA). We evaluated the activity of ceftaroline and compa...

    journal_title:Surgical infections

    pub_type: 杂志文章,多中心研究

    doi:10.1089/sur.2015.209

    authors: Sader HS,Farrell DJ,Flamm RK,Jones RN

    更新日期:2016-08-01 00:00:00

  • A prospective evaluation of the use of emergency department computed tomography for suspected acute appendicitis.

    abstract:BACKGROUND:Computed tomography (CT) is used increasingly to evaluate suspected cases of acute appendicitis (AA) in the emergency department (ED). This prospective study was performed to test the hypothesis that the evaluation of AA by CT in the ED remains suboptimal and that erroneous interpretation diminishes its util...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/109629601317202687

    authors: Maluccio MA,Covey AM,Weyant MJ,Eachempati SR,Hydo LJ,Barie PS

    更新日期:2001-10-01 00:00:00

  • Current Pneumonia Surveillance Methodology: Similar Underestimation in Trauma and Surgical Patients in the Intensive Care Unit.

    abstract:BACKGROUND:In 2013, the Centers for Disease Control and Prevention (CDC) developed new surveillance definitions for ventilator-associated events (VAE), leading to concerns that hospitals may be underreporting the true incidence of ventilator-associated pneumonias (VAPs). We sought to compare rates of clinically diagnos...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2016.152

    authors: Zosa BM,Golob JF,Conrad-Schnetz KJ,Schechtman D,Kreiner LA,Claridge JA

    更新日期:2017-07-01 00:00:00

  • Efficacy and Safety of Bunium Persicum (Boiss) to Inactivate Protoscoleces during Hydatid Cyst Operations.

    abstract:BACKGROUND:Current scolicidal agents, which have been used for inactivation of protoscoleces during surgical procedures, are associated with adverse side effects including sclerosing cholangitis. This investigation aimed to evaluate the scolicidal effects of Bunium persicum (Boiss) essential oil against protoscoleces o...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2016.010

    authors: Mahmoudvand H,Tavakoli Oliaei R,Mirbadie SR,Kheirandish F,Tavakoli Kareshk A,Ezatpour B,Mahmoudvand H

    更新日期:2016-12-01 00:00:00

  • Rapid adaptation of antibiotic therapy for community-acquired peritonitis using direct cultures on antibiotic agar plates: pilot study.

    abstract:BACKGROUND:Treatment of peritonitis requires prompt surgery and antibiotic therapy. It usually takes two or three days to obtain definitive results of peritoneal cultures and to adapt empirical antibiotic therapy. We assessed the potential time gain associated with direct culture of peritoneal samples on antibiotic aga...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2008.095

    authors: Lasocki S,Skurnik D,Muller-Serieys C,Bronchard R,Marcel C,Marmuse JP,Montravers P,Andremont A

    更新日期:2009-08-01 00:00:00

  • Liver abscess as a complication of laparoscopic gastric banding bariatric surgery.

    abstract:BACKGROUND:The World Health Organization has identified the rapidly growing prevalence of obesity as one of today's serious health problems. Various surgical interventions categorized collectively as bariatric surgery now play an ever-increasing important role as the only known effective treatment for severe obesity. L...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2012.023

    authors: Garrido D,Bush LM

    更新日期:2013-10-01 00:00:00

  • Use of negative-pressure wound therapy in breast tissues: evaluation of the literature.

    abstract:BACKGROUND:Negative-pressure wound therapy (NPWT) has been suggetsed to have a positive impact on the healing of sternal or extremity wounds. However, few data deriving from breast surgery have been published. We evaluated the available literature regarding the effectiveness of NPWT systems in the healing of breast tis...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2013.165

    authors: Kostaras EK,Tansarli GS,Falagas ME

    更新日期:2014-12-01 00:00:00

  • Extrahepatic primary adrenal alveolar echinococcosis: a review.

    abstract:BACKGROUND:Primary echinococcosis, and especially primary alveolar echinococcosis (AE) is rare among adrenal lesions. METHODS:We report a case of primary AE in a 28-year-old male with low backache and occasional upper limb pain lasting for six months, and review the pertinent but sparse literature on this disorder. R...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2012.037

    authors: Chu ZG,Lv FJ,Zhu ZY,Ouyang Y

    更新日期:2013-08-01 00:00:00

  • Literature Review of Criteria for Defining Recipient-Site Infection after Oral Oncologic Surgery with Simultaneous Reconstruction.

    abstract:BACKGROUND:The lack of uniformity of criteria for defining recipient-site infection after oral oncologic surgery with simultaneous reconstruction is problematic despite numerous studies on this issue. This study aimed to investigate the difference in the criteria for defining recipient-site infection after oral oncolog...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2017.101

    authors: Akashi M,Kusumoto J,Sakakibara A,Hashikawa K,Furudoi S,Komori T

    更新日期:2017-10-01 00:00:00

  • Efficacy of (99m)Tc-Labeled Ceftizoxime in the Diagnosis of Subclinical Infections Associated with Titanium Implants in Rats.

    abstract:BACKGROUND:Metal implants are used frequently in orthopedic procedures and the occurrence of subclinical low-virulence infection is difficult to diagnose. The objective of this study was to examine the hypothesis that peri-prosthetic subclinical infections may be diagnosed effectively in a murine model system using sci...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2014.186

    authors: Teixeira LE,Soares GG,Teixeira HC,Takenaka IK,Diniz SO,de Andrade MA,Cardoso VN,de Araújo ID

    更新日期:2015-06-01 00:00:00

  • Mediator responses in surgical infections.

    abstract:BACKGROUND:Surgical infections, and sepsis in particular, are characterized by extensive release of mediators. Our laboratories have been interested in understanding how these substances contribute to morbidity and mortality during various stages of surgical infections in order to develop new and more effective therape...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2006.7.s2-3

    authors: Aasen AO,Wang JE

    更新日期:2006-01-01 00:00:00

  • Hand infections: basic principles and management.

    abstract:BACKGROUND:An untreated hand infection can lead rapidly to tissue destruction and permanent disability. METHODS:Review of the pertinent English literature. RESULTS:Early diagnosis and timely, effective intervention is crucial to treatment. Anatomically, the hand consists of multiple potential spaces and tissue planes...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2004.5.210

    authors: Spann M,Talmor M,Nolan WB

    更新日期:2004-07-01 00:00:00

  • Abdominal wall thickness: is it associated with superficial and deep incisional surgical site infection after colorectal surgery?

    abstract:BACKGROUND:Colorectal surgical procedures have a high rate of surgical site infection (SSI), and obesity has been implicated as a predictor of such infection. We hypothesized that abdominal wall thickness (AWT), as a metric of obesity, would predict postoperative superficial and deep incisional SSI after colorectal sur...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2012.109

    authors: Kwaan MR,Sirany AM,Rothenberger DA,Madoff RD

    更新日期:2013-08-01 00:00:00