Abstract:
OBJECTIVE:To estimate the prevalence of use of fetal-harm drugs among women who received postpartum care in hospitals in Haiti and to identify groups of women at higher risk for potentially harmful medication exposures. METHODS:Women who received postpartum care in 2 large hospitals in Port-au-Prince, Haiti, from August 18 to December 1, 2008, were surveyed in Creole about their use of medications in pregnancy, including fetal-harm drugs. RESULTS:We surveyed 482 women who had a median age of 26 years. Approximately 75% reported using at least 1 medicine in pregnancy, with the most common being amoxicillin (n = 127), acetaminophen (n = 109), metronidazole (n = 79), and misoprostol (n = 38). More than 13% used fetal-harm drugs, including misoprostol and tetracycline. Unmarried women (adjusted relative risk [RR] 2.2; 95% confidence interval [CI], 1.0-4.7) and separated women (adjusted RR 4.6; CI, 1.8-11.9) were more likely than married women to report use of fetal-harm drugs. In addition, women with 4 or more children were more likely to report use of medications known to cause fetal harm (adjusted RR 4.3; CI, 1.9-9.9). CONCLUSION:Women who delivered infants in Haiti commonly report use of fetal-harm drugs. The public health implications of these findings are broad and relate to complex issues such as pregnancy planning and regulation of medications to prevent potentially harmful exposures.
journal_name
Acad Pediatrjournal_title
Academic pediatricsauthors
Jules A,Kaltenbach LA,Arbogast PG,Caples TL,Po'e EK,Cooper WOdoi
10.1016/j.acap.2010.09.003subject
Has Abstractpub_date
2010-11-01 00:00:00pages
395-9issue
6eissn
1876-2859issn
1876-2867pii
S1876-2859(10)00252-4journal_volume
10pub_type
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pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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