Abstract:
:The aim of this work was to develop a new production, recovery and formulation process of gibberellic acid (GA3). Low-cost byproducts - citrus pulp (CP) and soybean hulls (SH) - were employed as substrate for GA3 production by Gibberella fujikuroi in semisolid fermentation. A CP/SH mixture (70%/30%) promoted high productivities both in bubble column reactor (1.66 mg L/h), and in stirred tank reactor (2.13 mg L/h). GA3 production medium cost (US$ 6.70/m3) was reduced by 85% when compared to previously reported synthetic media (US$ 44.96/m3). It was described that GA3 fermented extract has low stability, and that liquid and powder formulation of the fermented extract maintained the biomolecule activity over 6 months. Alginate and alginate/kefiran beads containing GA3 showed encapsulation efficiency of 70% and 60%, respectively. This work supports good perspectives for GA3 production using cheap substrates and simple formulation of clarified extract to favour its use in agricultural countries.
journal_name
Bioresour Technoljournal_title
Bioresource technologyauthors
Camara MC,Vandenberghe LPS,Sextos GC,Tanobe VOA,Magalhães Junior AI,Soccol CRdoi
10.1016/j.biortech.2020.123295subject
Has Abstractpub_date
2020-08-01 00:00:00pages
123295eissn
0960-8524issn
1873-2976pii
S0960-8524(20)30567-8journal_volume
309pub_type
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