Dynamic treatment regimes for managing chronic health conditions: a statistical perspective.

Abstract:

:Dynamic treatment regimes are an emerging and important methodological area in health research, particularly in the management of chronic health conditions. This paradigm encompasses the ideological shift in research from the acute care model to the chronic care model. It allows individualization of treatment (type, dosage, timing) at each stage of intervention. Constructing evidence-based dynamic treatment regimes requires implementation of cutting-edge design and analysis tools. Here I briefly discuss some of these modern tools, namely the sequential multiple assignment randomized trial (SMART) design and a regression-based analysis approach called Q-learning.

journal_name

Am J Public Health

authors

Chakraborty B

doi

10.2105/AJPH.2010.198937

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

40-5

issue

1

eissn

0090-0036

issn

1541-0048

pii

AJPH.2010.198937

journal_volume

101

pub_type

杂志文章
  • Population density and the rate of mental illness.

    abstract::An examination of age specific rates of psychiatric admissions within Brooklyn, New York, indicated that population density may function as an intervening variable in the production of mental illness. Measures of household and family contact were found to be significantly correlated to four rates of hospital utilizati...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.67.12.1165

    authors: Schweitzer L,Su WH

    更新日期:1977-12-01 00:00:00

  • The relationship of patient reading ability to self-reported health and use of health services.

    abstract:OBJECTIVES:This study examined the relationship of functional health literacy to self-reported health and use of health services. METHODS:Patients presenting to two large, urban public hospitals in Atlanta, Ga, and Torrance, Calif, were administered a health literacy test about their overall health and use of health c...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.87.6.1027

    authors: Baker DW,Parker RM,Williams MV,Clark WS,Nurss J

    更新日期:1997-06-01 00:00:00

  • Industry Payments to Physicians for Opioid Products, 2013-2015.

    abstract:OBJECTIVES:To identify payments that involved opioid products from the pharmaceutical industry to physicians. METHODS:We used the Open Payments program database from the Centers for Medicare and Medicaid Services to identify payments involving an opioid to physicians between August 2013 and December 2015. We used medi...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2017.303982

    authors: Hadland SE,Krieger MS,Marshall BDL

    更新日期:2017-09-01 00:00:00

  • Police Brutality and Black Health: Setting the Agenda for Public Health Scholars.

    abstract::We investigated links between police brutality and poor health outcomes among Blacks and identified five intersecting pathways: (1) fatal injuries that increase population-specific mortality rates; (2) adverse physiological responses that increase morbidity; (3) racist public reactions that cause stress; (4) arrests, ...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2017.303691

    authors: Alang S,McAlpine D,McCreedy E,Hardeman R

    更新日期:2017-05-01 00:00:00

  • Powerful connections for public health: the National Library of Medicine and the National Network of Libraries of Medicine.

    abstract::As incorporated in Healthy People 2010 objectives, data and information systems and a skilled workforce are 2 of the critical components of the public health infrastructure. The National Library of Medicine (NLM) and the National Network of Libraries of Medicine (NN/LM) are important resources for improving Internet a...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.89.11.1633

    authors: Humphreys BL,Ruffin AB,Cahn MA,Rambo N

    更新日期:1999-11-01 00:00:00

  • Estimating the World Trade Center tower population on September 11, 2001: a capture-recapture approach.

    abstract::I applied the capture-recapture method to estimate the World Trade Center tower population at the time of the September 11, 2001, terrorist attacks. Available lists helped identify 8965 survivors and 2152 confirmed casualties. The capture-recapture model suggested that an additional 4435 survivors were present, puttin...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2007.124768

    authors: Murphy J

    更新日期:2009-01-01 00:00:00

  • Swimming pool drownings among US residents aged 5-24 years: understanding racial/ethnic disparities.

    abstract:OBJECTIVE:We examined circumstances surrounding swimming pool drownings among US residents aged 5 to 24 years to understand why Black males and other racial/ethnic groups have high drowning rates. METHODS:We obtained data about drowning deaths in the United States (1995-1998) from death certificates, medical examiner ...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2004.057067

    authors: Saluja G,Brenner RA,Trumble AC,Smith GS,Schroeder T,Cox C

    更新日期:2006-04-01 00:00:00

  • Risk of infection from needle reuse at a phlebotomy center.

    abstract:OBJECTIVES:This study determined infection risk for HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) from needle reuse at a phlebotomy center that possibly exposed 3810 patients to infection. METHODS:We used a model for the risk of infection per blood draw, supplemented by subsequent testing results from 1699...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.91.4.636

    authors: Porco TC,Aragón TJ,Fernyak SE,Cody SH,Vugia DJ,Katz MH,Bangsberg DR

    更新日期:2001-04-01 00:00:00

  • Optimal indicators of socioeconomic status for health research.

    abstract:OBJECTIVES:In this study we examined the relationship between indicators of socioeconomic status (SES) and mortality for a representative sample of individuals. METHODS:The sample included 3734 individuals aged 45 and older interviewed in 1984 in the Panel Study of Income Dynamics. In the current study, mortality was ...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.92.7.1151

    authors: Daly MC,Duncan GJ,McDonough P,Williams DR

    更新日期:2002-07-01 00:00:00

  • Undocumented Immigration, Drug Problems, and Driving Under the Influence in the United States, 1990-2014.

    abstract:OBJECTIVES:To examine the influence of undocumented immigration in the United States on 4 different metrics of drug and alcohol problems: drug arrests, drug overdose fatalities, driving under the influence (DUI) arrests, and DUI deaths. METHODS:We combined newly developed state-level estimates of the undocumented popu...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2017.303884

    authors: Light MT,Miller T,Kelly BC

    更新日期:2017-09-01 00:00:00

  • Neighborhood predictors of dating violence victimization and perpetration in young adulthood: a multilevel study.

    abstract:OBJECTIVES:We examined whether social processes of neighborhoods, such as collective efficacy, during individual's adolescent years affect the likelihood of being involved in physical dating violence during young adulthood. METHODS:Using longitudinal data on 633 urban youths aged 13 to 19 years at baseline and data fr...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2009.169730

    authors: Jain S,Buka SL,Subramanian SV,Molnar BE

    更新日期:2010-09-01 00:00:00

  • The effect of antidepressant warnings on prescribing trends in Ontario, Canada.

    abstract:OBJECTIVES:We studied whether 5 regulatory agency advisories concerning the possible increased risk of suicidal behavior during antidepressant therapy had an effect on antidepressant prescription trends in Ontario. METHODS:We conducted a population-based, time-series analysis of new monthly antidepressant prescription...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2006.087262

    authors: Kurdyak PA,Juurlink DN,Mamdani MM

    更新日期:2007-04-01 00:00:00

  • Low-risk lifestyle behaviors and all-cause mortality: findings from the National Health and Nutrition Examination Survey III Mortality Study.

    abstract:OBJECTIVES:We examined the relationship between 4 low-risk behaviors-never smoked, healthy diet, adequate physical activity, and moderate alcohol consumption-and mortality in a representative sample of people in the United States. METHODS:We used data from 16958 participants aged 17 years and older in the National Hea...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2011.300167

    authors: Ford ES,Zhao G,Tsai J,Li C

    更新日期:2011-10-01 00:00:00

  • Capodanno Senza Danno: the effects of an intervention program on fireworks injuries in Naples.

    abstract::To study the effects of a comprehensive, multifaceted intervention program to reduce fireworks-related injuries during the Italian New Year's holiday season, active surveillance was conducted in the 18 public emergency rooms of Naples, Italy, before and after implementation of the program. Preintervention data collect...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.86.1.84

    authors: D'Argenio P,Cafaro L,Santonastasi F,Taggi F,Binkin N

    更新日期:1996-01-01 00:00:00

  • Exercise prescription: a clinical trial.

    abstract::To assess the effectiveness of physician prescribed exercise, health education, and patient self-monitoring, 124 firefighters were medically screened and randomly allocated to a control and two treatment groups. Physiologic and reporting methods were employed to assess adherence to regular exercise at three months and...

    journal_title:American journal of public health

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2105/ajph.69.6.591

    authors: Reid EL,Morgan RW

    更新日期:1979-06-01 00:00:00

  • Women's health after pregnancy and child outcomes at age 3 years: a prospective cohort study.

    abstract:OBJECTIVES:This study examined the persistence and comorbidity of women's physical and mental health conditions after pregnancy and the association of these conditions with child outcomes. METHODS:A national cohort of women who recently gave birth were surveyed in 1988 and again in 1991. We examined longitudinal data ...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.92.8.1312

    authors: Kahn RS,Zuckerman B,Bauchner H,Homer CJ,Wise PH

    更新日期:2002-08-01 00:00:00

  • Childhood maltreatment histories, alcohol and other drug use symptoms, and sexual risk behavior in a treatment sample of adolescents.

    abstract:OBJECTIVES:We tested a structural model of relations among self-reported childhood maltreatment, alcohol and other drug abuse and dependence symptoms, and sexual risk behavior in a sample of adolescents receiving outpatient treatment of substance use problems. METHODS:Structured interviews were administered to an ethn...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2011.300628

    authors: Oshri A,Tubman JG,Burnette ML

    更新日期:2012-05-01 00:00:00

  • The nutritional status of the elderly in Russia, 1992 through 1994.

    abstract:OBJECTIVES:The purpose of this study was to ascertain how economic reform has affected nutritional well-being of the elderly in the Russian Federation. METHODS:A sample of more than 2932 Russians 60 years of age and older was selected from a nationally representative survey of Russian households. A 24-hour dietary rec...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.86.3.355

    authors: Popkin BM,Zohoori N,Baturin A

    更新日期:1996-03-01 00:00:00

  • Perception of risk of vertically acquired HIV infection and acceptability of provider-initiated testing and counseling among adolescents in Zimbabwe.

    abstract:OBJECTIVES:We investigated attitudes toward provider-initiated HIV testing and counseling (PITC) in the suburbs of Harare, Zimbabwe, where late presentation after mother-to-child HIV transmission (MTCT) is a major cause of adolescent mortality. METHODS:Adolescents (10-18 years) attending 2 primary clinics were offered...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2011.300250

    authors: Ferrand RA,Trigg C,Bandason T,Ndhlovu CE,Mungofa S,Nathoo K,Gibb DM,Cowan FM,Corbett EL

    更新日期:2011-12-01 00:00:00

  • US Public Health Agency involvement in youth-focused illicit drug policy, planning, and prevention at the local level, 1999-2003.

    abstract:OBJECTIVES:We examined local public health agencies' involvement in community illicit drug policy advocacy and provision related to youths to determine the extent to which public health agencies were involved in local drug policy activities and could potentially provide an infrastructure for policy alternatives. METHO...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2007.112524

    authors: McBride DC,Terry-McElrath YM,VanderWaal CJ,Chriqui JF,Myllyluoma J

    更新日期:2008-02-01 00:00:00

  • Outcomes of a breast health project for Hmong women and men in California.

    abstract:OBJECTIVES:We used a community-based research approach to test a culturally based breast cancer screening program among low-income Hmong women in central and southern California. METHODS:We designed a culturally informed educational program with measures at baseline and 1-year follow-up in 2 intervention cities and 1 ...

    journal_title:American journal of public health

    pub_type: 杂志文章,多中心研究

    doi:10.2105/AJPH.2008.143974

    authors: Kagawa-Singer M,Tanjasiri SP,Valdez A,Yu H,Foo MA

    更新日期:2009-10-01 00:00:00

  • Motorcycle helmet use and injury outcome and hospitalization costs from crashes in Washington State.

    abstract:OBJECTIVES:The incidence, type, severity, and costs of crash-related injuries requiring hospitalization or resulting in death were compared for helmeted and unhelmeted motorcyclists. METHODS:This was a retrospective cohort study of injured motorcyclists in Washington State in 1989. Motorcycle crash data were linked to...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.86.1.41

    authors: Rowland J,Rivara F,Salzberg P,Soderberg R,Maier R,Koepsell T

    更新日期:1996-01-01 00:00:00

  • Impact of Two Adolescent Pregnancy Prevention Interventions on Risky Sexual Behavior: A Three-Arm Cluster Randomized Control Trial.

    abstract:OBJECTIVES: To test the efficacy of Reducing the Risk (RTR) and Love Notes (LN) on reducing risky sexual behavior among youths yet to experience or cause a pregnancy. METHODS: The four dependent variables were ever had sex, condom use, birth control use, and number of sexual partners at 3- and 6-month follow-up in a 3...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2016.303429

    authors: Barbee AP,Cunningham MR,van Zyl MA,Antle BF,Langley CN

    更新日期:2016-09-01 00:00:00

  • Behavioral risk reduction in a declining HIV epidemic: injection drug users in New York City, 1990-1997.

    abstract:OBJECTIVES:This study assessed trends in HIV risk behaviors among injection drug users in New York City from 1990 to 1997. METHODS:Injection drug users were recruited continuously from a large drug detoxification treatment program (N = 2588) and a research storefront located in a high-drug-use area (N = 2701). Informe...

    journal_title:American journal of public health

    pub_type: 杂志文章,多中心研究

    doi:10.2105/ajph.90.7.1112

    authors: Des Jarlais C,Perlis T,Friedman SR,Chapman T,Kwok J,Rockwell R,Paone D,Milliken J,Monterroso E

    更新日期:2000-07-01 00:00:00

  • Parent-Centered Prevention of Risky Behaviors Among Hispanic Youths in Florida.

    abstract:OBJECTIVES:To evaluate the effectiveness of an evidence-based, parent-centered intervention, Familias Unidas, delivered by nonresearch personnel, in preventing substance use (alcohol, illicit drugs) and sex without a condom among Hispanic adolescents. METHODS:A randomized controlled trial (n = 746) evaluated the effec...

    journal_title:American journal of public health

    pub_type: 杂志文章,随机对照试验

    doi:10.2105/AJPH.2017.303653

    authors: Estrada Y,Lee TK,Huang S,Tapia MI,Velázquez MR,Martinez MJ,Pantin H,Ocasio MA,Vidot DC,Molleda L,Villamar J,Stepanenko BA,Brown CH,Prado G

    更新日期:2017-04-01 00:00:00

  • Leisure time physical activity and disease-specific mortality among men with chronic bronchitis: evidence from the Whitehall study.

    abstract:OBJECTIVES:This study examined the association between leisure time physical activity and cause-specific mortality among male Whitehall Study participants with chronic bronchitis. METHODS:Rate ratios were calculated for 4 mortality outcomes, according to level of activity and baseline bronchitis status, in a 25-year f...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.93.5.817

    authors: Batty GD,Shipley MJ,Marmot MG,Smith GD

    更新日期:2003-05-01 00:00:00

  • Evaluation of the impact of news coverage of an HIV multiclass drug-resistant cluster in Seattle, Washington.

    abstract:OBJECTIVES:In February 2007, Public Health-Seattle and King County issued a press release describing a cluster of multiclass drug-resistant HIV cases among men who had sex with men (MSM). We evaluated the effect of the press release among MSM in the Seattle area. METHODS:We administered a rapid assessment survey at ve...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2007.126656

    authors: Kahle EM,Barash EA,Page LC,Lansky A,Jafa K,Sullivan PS,Buskin SE

    更新日期:2009-04-01 00:00:00

  • Risk factors for early adolescent drug use in four ethnic and racial groups.

    abstract:OBJECTIVES:It is widely believed that risk factors identified in previous epidemiologic studies accurately predict adolescent drug use. Comparative studies are needed to determine how risk factors vary in prevalence, distribution, sensitivity, and pattern across the major US ethnic/racial groups. METHODS:Baseline ques...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/ajph.83.2.185

    authors: Vega WA,Zimmerman RS,Warheit GJ,Apospori E,Gil AG

    更新日期:1993-02-01 00:00:00

  • Adult socioeconomic position and the association between height and coronary heart disease mortality: findings from 33 years of follow-up in the Whitehall Study.

    abstract::In the Whitehall Study, which followed 17,139 male civil servants over 33 years, the association between tall stature and coronary heart disease (CHD) mortality differed between employment grades. In men without CHD at study entry, the hazard ratio per 15-cm increase in height was 0.77 (95% confidence interval [CI]=0....

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/2004.046219

    authors: Langenberg C,Shipley MJ,Batty GD,Marmot MG

    更新日期:2005-04-01 00:00:00

  • Moving upstream: why rehabilitative justice in military discharge proceedings serves a public health interest.

    abstract::The cultural divide between US military and civilian institutions amplifies the consequences of military discharge status on public health and criminal justice systems in a manner that is invisible to a larger society. Prompt removal of problematic wounded warriors through retributive justice is more expedient than le...

    journal_title:American journal of public health

    pub_type: 杂志文章

    doi:10.2105/AJPH.2014.302117

    authors: Seamone ER,McGuire J,Sreenivasan S,Clark S,Smee D,Dow D

    更新日期:2014-10-01 00:00:00