Novel compound LL-a produces long and nociceptive-selective regional anesthesia via TRPV1 channels in rodents sciatic nerve block model.

abstract：BACKGROUND AND OBJECTIVES:Amputations of the lower extremity remain a common procedure in a high-risk population. Perioperative morbidity and mortality reach as high as 14.1% in below-knee amputations. We aimed to determine whether regional, or neuraxial, anesthesia, when compared with general anesthesia (GA), would be...

journal_title：Regional anesthesia and pain medicine

authors： Malik O,Brovman EY,Urman RD

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to compare the potency of bupivacaine, ropivacaine, and levobupivacaine in an equal dose and concentration for sympathetic block. METHODS:We measured mean arterial pressure, heart rate (HR), and right and left brachial artery blood flow (BABF) before and after cervic...

journal_title：Regional anesthesia and pain medicine

authors： Hashimoto T,Iwasaki T,Takahashi Y,Kimura Y,Nagao M,Yamaguchi S,Hamaguchi S,Kitajima T

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We present 2 case reports that illustrate that chronic intrathecal (IT) baclofen administration may be efficacious in treating patients with long-standing complex regional pain syndrome, type I (CRPS I) who have failed treatment with multiple drugs and procedures. CASE REPORTS:Both cases pres...

journal_title：Regional anesthesia and pain medicine

authors： Zuniga RE,Perera S,Abram SE

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This case series assesses the in vivo spread of contrast within the adductor canal in subjects who recently underwent a total knee arthroplasty. A previous analysis of profound leg weakness with a continuous adductor canal revealed contrast spread from the adductor canal to the femoral triangl...

journal_title：Regional anesthesia and pain medicine

authors： Yuan SC,Hanson NA,Auyong DB,Choi DS,Coy D,Strodtbeck WM

更新日期：2015-03-01 00:00:00

abstract：:Potassium (K+) channels form the largest family of ion channels with more than 70 such genes identified in the human genome. They are organized in 3 superfamilies according to their predicted membrane topology: (1) subunits with 6 membrane-spanning segments and 1-pore domain, (2) subunits with 2 membrane-spanning segm...

journal_title：Regional anesthesia and pain medicine

authors： Kindler CH,Yost CS

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Anesthesia and analgesia with paravertebral block are reportedly variable. Existence of an endothoracic fascia has been proposed as one of the possible mechanisms leading to variability. We undertook an electron-microscopy imaging study to investigate the endothoracic fascia in the thoracic pa...

journal_title：Regional anesthesia and pain medicine

authors： Stopar Pintaric T,Veranic P,Hadzic A,Karmakar M,Cvetko E

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Ultrasound-guided infiltration of the interspace between the popliteal artery and capsule of the knee (iPACK) block, a new regional analgesic technique, is believed to relieve posterior knee pain, after total knee arthroplasty, by targeting the articular branches innervating posterior aspect o...

journal_title：Regional anesthesia and pain medicine

authors： Tran J,Giron Arango L,Peng P,Sinha SK,Agur A,Chan V

更新日期：2019-05-06 00:00:00

abstract：OBJECTIVE:Local anesthetic-induced cardiotoxicity remains a complication of regional anesthesia, with the potential to result in cardiac arrest refractory to resuscitation. Successful resuscitation using Intralipid (Baxter Pharmaceuticals by Fresenius Kabi, Uppsala, Sweden), has been reported in 2 patients with bupivac...

journal_title：Regional anesthesia and pain medicine

authors： McCutchen T,Gerancher JC

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Spontaneous intracranial hypotension is a postural headache syndrome unrelated to dural puncture. Due to the apparent failure of epidural blood patch to relieve headache in spontaneous intracranial hypotension, we investigated the epidemiologic features and treatment outcomes of this condition...

journal_title：Regional anesthesia and pain medicine

authors： Diaz JH

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Detailed description of the tasks anesthetists undertake during the performance of a complex procedure, such as ultrasound-guided peripheral nerve blockade, allows elements that are vulnerable to human error to be identified. We have applied 3 task analysis tools to one such procedure, namely, ultrasound-gui...

journal_title：Regional anesthesia and pain medicine

authors： O'Sullivan O,Aboulafia A,Iohom G,O'Donnell BD,Shorten GD

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Ultrasound (US) guidance, in some instances, can increase the success rate and reduce the onset and procedure times for peripheral nerve blockade compared with traditional nerve localization techniques. The presumptive mechanism for these benefits is the ability to accurately inject local anesthetic circumfe...

journal_title：Regional anesthesia and pain medicine

authors： Brull R,Macfarlane AJ,Parrington SJ,Koshkin A,Chan VW

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Ropivacaine is a potent local anesthetic that, experimentally at low concentrations, produces an effective block of pain conducting nerve fibers. Therefore, it was hypothesized that 0.1% and 0.2% ropivacaine would provide clinically adequate postoperative analgesia in continuous axillary plexu...

journal_title：Regional anesthesia and pain medicine

authors： Salonen MH,Haasio J,Bachmann M,Xu M,Rosenberg PH

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Continuous brachial plexus blocks at the interscalene level are associated with known diaphragm dysfunction from phrenic nerve paresis. More distal blocks along the brachial plexus may provide postsurgical analgesia while potentially having less effect on diaphragm function. Continuous intersc...

journal_title：Regional anesthesia and pain medicine

authors： Auyong DB,Yuan SC,Choi DS,Pahang JA,Slee AE,Hanson NA

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Prior to this investigation, there was no approach to compare both the potency of local anesthetics and their time course of action in a reproducible nociceptive system in humans. We tested whether the vascularly isolated vein segment is appropriate for such an approach. METHODS:In six health...

journal_title：Regional anesthesia and pain medicine

authors： Holthusen H,Lipfert P,Klement W

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Poorly controlled postoperative pain is strongly associated with the development of chronic pain. We aimed to investigate the effect of topical morphine (in 1 of 3 doses: 5, 10, or 15 mg) on acute and chronic neuropathic pain after modified radical mastectomy for cancer breast. METHODS:In thi...

journal_title：Regional anesthesia and pain medicine

authors： Mohamed SA,Abdel-Ghaffar HS,Kamal SM,Fares KM,Hamza HM

更新日期：2016-11-01 00:00:00

abstract：:The progression of sensory blockade in the hand following a forearm Bier block with ropivacaine is currently unknown. The hands of 10 healthy adult human subjects were anesthetized with ropivacaine, and their sensitivities to cold and touch were tested until the completion of anesthesia. On average, insensitivity to c...

journal_title：Regional anesthesia and pain medicine

authors： Horn JL,Cordo P,Künster D,Harvey C,Cherry A,Bratt A,Gurfinkel V

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Although uncommon, residual effects from contrast agents used more than 2 decades ago are possible. This case report is to alert clinicians to the implications of residual oil-based ionic contrast agents in the intrathecal space. CASE REPORT:A 70-year-old female with evidence of degenerative disc disease und...

journal_title：Regional anesthesia and pain medicine

authors： Navani A,Dominguez CL,Hald JK,Fishman SM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Concern for block-related injury and liability has dissuaded many anesthesiologists from using regional anesthesia for eye and extremity surgery, despite many studies demonstrating the benefits of regional over general anesthesia. To determine injury patterns and liability associated with eye ...

journal_title：Regional anesthesia and pain medicine

authors： Lee LA,Posner KL,Cheney FW,Caplan RA,Domino KB

更新日期：2008-09-01 00:00:00

abstract：:This study aimed to describe the anatomical distribution of dye injected in the erector spinae plane (ESP) in a porcine living model, which could aid to reveal factors potentially relevant to the unexplained clinical effects of the ESP block. Six pigs received 0.6 mL/kg of 0.25% new methylene blue at the level of the ...

journal_title：Regional anesthesia and pain medicine

authors： Otero PE,Fuensalida SE,Russo PC,Verdier N,Blanco C,Portela DA

更新日期：2020-03-01 00:00:00

abstract：:Contemporary nonmalignant pain treatment algorithms commence with conservative non-invasive strategies, later progressing from minimally invasive interventions to invasive techniques or implantable devices. The most commonly used implantable devices are spinal cord stimulation (SCS) systems or targeted drug delivery (...

journal_title：Regional anesthesia and pain medicine

authors： Mekhail N,Mehanny DS,Armanyous S,Costandi S,Saweris Y,Azer G,Bolash R

更新日期：2020-01-12 00:00:00

abstract：OBJECTIVE:Although complications of the epidural technique are known to affect the fetus adversely, there are no data indicating that regional analgesia directly causes harmful effects to the fetus. Our purpose was to determine the effect of epidural labor analgesia on the Doppler velocimetric indices of the uterine an...

journal_title：Regional anesthesia and pain medicine

authors： Chen LK,Yang YM,Yang YH,Lee CN,Chen SS,Sun WZ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Whether patients titrate themselves to an individualized blood or plasma opioid concentration (the so-called minimum effective concentration or [MEC]) has been debated extensively. Nevertheless, there is consistent opinion that during patient controlled analgesia (PCA) patients balance accepta...

journal_title：Regional anesthesia and pain medicine

authors： Woodhouse A,Mather LE

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The benefit of adding sciatic nerve block (SNB) to femoral nerve block to improve analgesia after total knee arthroplasty (TKA) is uncertain. We hypothesized that the effective duration of single-injection SNB is too short to improve postoperative analgesia and that this contributes to conflic...

journal_title：Regional anesthesia and pain medicine

authors： Sato K,Adachi T,Shirai N,Naoi N

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The incidence of postdural puncture headache (PDPH) after epidural wet tap for obstetric patients may be as high as 75%. We have studied how subsequent placement of a subarachnoid catheter immediately after confirmation of a wet tap, and leaving the catheter in place for 24 hours affects the i...

journal_title：Regional anesthesia and pain medicine

authors： Ayad S,Demian Y,Narouze SN,Tetzlaff JE

更新日期：2003-11-01 00:00:00

abstract：:The use of ultrasound to facilitate regional anesthesia is an evolving area of clinical, education, and research interests. As our community's experience grows, it has become evident that anesthesiologists performing "routine" ultrasound-guided blocks may very well be confronted with atypical or even pathologic anatom...

journal_title：Regional anesthesia and pain medicine

authors： Sites BD,Macfarlane AJ,Sites VR,Naraghi AM,Chan VW,Antonakakis JG,Singh M,Brull R

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Sacroiliac joint injections are frequently performed procedures in the management of acute and chronic low-back pain, including patients with various immunocompromised states. Infectious complications following these procedures along with other spinal injections are rarely reported, but the true incidence is ...

journal_title：Regional anesthesia and pain medicine

authors： Nagpal G,Flaherty JP,Benzon HT

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:To describe a late neurologic complication of intrathecal pump implantation and show the methods used for the diagnosis and successful treatment of transverse myelitis in this setting. CASE REPORT:A 32-year-old man with a chronic abdominal pain syndrome presented with right lower-extremity numbness 2 months ...

journal_title：Regional anesthesia and pain medicine

authors： Ubogu EE,Lindenberg JR,Werz MA

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Third occipital nerve block (TONB) is commonly used in the diagnosis and treatment of upper neck pain and cervicogenic headaches. Although fluoroscopy is the current imaging standard for TONB, ultrasound (US) guidance offers a promising, radiation-free alternative. In this randomized, observer-blinded trial,...

journal_title：Regional anesthesia and pain medicine

authors： Finlayson RJ,Etheridge JP,Vieira L,Gupta G,Tran DQ

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:We present an occurrence of a severe but transient neurologic complication after intraneural injection during an ultrasound-guided interscalene block. CASE REPORT:A 36-year-old man underwent ultrasound-guided interscalene nerve blockade before shoulder incision and drainage. On postoperative day 1, he exhibi...

journal_title：Regional anesthesia and pain medicine

authors： Cohen JM,Gray AT

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Peripheral nerve blocks reduce postoperative pain and enhance recovery after total knee arthroplasty (TKA). This study aims to assess the benefits of addition of intravenous dexmedetomidine (DexM) to intravenous dexamethasone on the analgesic duration of quadruple nerve blocks. METHODS:This d...

journal_title：Regional anesthesia and pain medicine

authors： Chassery C,Marty P,Rontes O,Chaubard M,Vuillaume C,Basset B,Merouani M,Marquis C,De Lussy A,Delbos MC,Casalprim J,Bataille B,Naudin C,Ferre F,Delbos A

更新日期：2021-02-01 00:00:00