Abstract：
:Emergency laparotomy (EL) is a high-risk procedure. However, available evidence regarding outcome after emergency surgery in very old patients is limited. The aim of this observational study was to investigate outcome following EL in patients ≥80 years of age. METHODS:This single-center retrospective study was undertaken at Haukeland University Hospital, Norway. Demographic data, pre-operative risk assessment, surgical procedures, intrahospital logistics, complications, mortality, and discharge data were collected from the medical records. Primary outcome was 30-day mortality. Secondary outcomes were 90-day mortality, 1-year mortality, post-operative complications, and level of care at discharge. RESULTS:One hundred and six patients aged 80-96 years underwent EL between 2015 and 2016. Of these, 58% had cardiopulmonary disease, and 16% lived in a nursing home before surgery. Resection of colon was performed in 26 cases, adhesiolysis was performed in 24, and resection of small intestine in 18. Within 30 days, 28 patients died (26%), 15 during the first post-operative week. For 82% of the patients, at least one complication occurred, and medical complications were far more frequent than surgical. Post-operatively, pulmonary morbidity was found in 51 patients (48%) and delirium in 42 (40%). The number of intrahospital deaths was 25 (24%). Among the 81survivors, 53 were discharged to a nursing home (65%). One-year mortality was 47% (50/106). CONCLUSIONS:Mortality after EL in octo- and nonagenarians is very high. Medical complications are more common than surgical, and functional decline is frequent. Future studies should focus on the effect of a care bundle including geriatric intervention in these patients.
journal_name
Acta Anaesthesiol Scandjournal_title
Acta anaesthesiologica Scandinavicaauthors
Aakre EK,Ulvik A,Hufthammer KO,Jammer Idoi
10.1111/aas.13594subject
Has Abstractpub_date
2020-08-01 00:00:00pages
913-919issue
7eissn
0001-5172issn
1399-6576journal_volume
64pub_type
杂志文章abstract：BACKGROUND:It has been shown that spinal reflexes such as the H-reflex predict motor responses to painful stimuli better than cortical parameters derived from the EEG. The precise concentration-dependence of H-reflex suppression by anaesthetics, however, is not known. Here we investigated this concentration-response re...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章
doi：10.1111/j.1399-6576.2004.00372.x
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:Baricity is one of the most important factors to influence the characteristics of distribution of the local anaesthetic and hence success and spread of the blockade. Bupivacaine is rendered hyperbaric by adding glucose. The effect of differing degrees of hyperbaricity remains to be evaluated. METHODS:Two hy...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1034/j.1399-6576.2000.00510.x
更新日期：2000-05-01 00:00:00
abstract：BACKGROUND:There is some evidence that propofol may reduce post-operative pain. However, the results on the analgesic effects of propofol are inconsistent. Thus, we hypothesized that propofol reduces acute pain if confounding factors like opioids are avoided. METHODS:In this prospective, randomized, subject- and asses...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1399-6576.2011.02603.x
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:Two spinal anaesthesia techniques were compared with local infiltration anaesthesia (LIA) to test the hypothesis that the addition of lidocaine to bupivacaine would decrease the spinal block's duration and provide shorter recovery to discharge. METHODS:Ninety-three patients undergoing outpatient herniorrhap...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/aas.12175
更新日期：2013-11-01 00:00:00
abstract：:Immediate attempts to resuscitate patients with cardiac arrest by lay bystanders distinctly increase the chances of survival in such patients. In the present study we investigated possibilities of intensifying the cardiopulmonary resuscitation (CPR) training of laymen. A group of 46 young conscripts (test group) was g...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1979.tb01445.x
更新日期：1979-06-01 00:00:00
abstract：:The new anesthetic inhalation agent, enflurane, is supposed to allow rapid induction and recovery. Experinece with this agent in obstetrics is limited. Enflurane was therefore studied in 14 pregnant women undergoing elective cesarean section. Its effects upon the respiratory adaptation of the newborn infants were foll...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1976.tb05021.x
更新日期：1976-01-01 00:00:00
abstract：:The effects of the non-depolarizing muscle relaxants pancuronium (Pancuronium) and vecuronium (Norcuron) (0.1 mg/kg) on myocardial blood flow, myocardial oxygen consumption, myocardial lactate balance, cardiovascular dynamics and electrocardiogram were studied in two groups of eight patients undergoing coronary artery...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1399-6576.1990.tb03096.x
更新日期：1990-07-01 00:00:00
abstract：:A schizophrenic patient on long-time neuroleptic medication was admitted with ileus. Secondarily, a high fever, rigidity, mental confusion, tachycardia and hypotension developed. After bromocriptine was given, the temperature dropped by 2 degrees C and the patient improved markedly. A diagnosis of neuroleptic malignan...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1399-6576.2003.00193.x
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND:Ropivacaine is the first S-enantiomer aminoamide local anaesthetic in clinical use, and has been found to be less toxic than bupivacaine. Caudal ropivacine has been shown to cause less motor blockade and longer duration of analgesia in the postoperative period than bupivacaine in children. Plasma levels of r...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1034/j.1399-6576.2000.440911.x
更新日期：2000-10-01 00:00:00
abstract：:In ten elderly patients subjected to extensive thoracolumbar epidural anaesthesia, circulatory changes were studied before and during sympathetic stimulation. Induced hypercapnia was used as a sympathetic stimulus. After establishment of the epidural anaesthesia, which extended from T1 to L2, there were decreases in h...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1987.tb02536.x
更新日期：1987-02-01 00:00:00
abstract：:During thiopentone-fentanyl-nitrous oxide anaesthesia and using a cumulative design, we studied the dose-response relationship of mivacurium in 8 patients: 7 patients phenotypically homozygous for the atypical plasma cholinesterase gene and 1 patient homozygous for the silent gene. The estimated mean ED50 and ED95 wer...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1995.tb04220.x
更新日期：1995-11-01 00:00:00
abstract：UNLABELLED:In this prospective, consecutive study, 191 patients were interviewed before and after surgery (orthopaedic, gynaecological, abdominal and urological operations) about their attitude to and the quality of received pain relief, respectively. In addition, nurses working in the surgical units involved in the st...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1993.tb03737.x
更新日期：1993-05-01 00:00:00
abstract：BACKGROUND:Articaine and chloroprocaine have recently gained interest as short-acting spinal anaesthetics. Based on previous work comparing articaine 60 mg with chloroprocaine 40 mg, we hypothesised that articaine 40 mg and chloroprocaine 40 mg would produce similar spinal anaesthesa regarding block onset, maximal spre...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/aas.12107
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Post-operative sepsis considerably increases mortality, but the extent of pre-operative sepsis in hip fracture patients and its consequences are sparsely elucidated. The aim of this study was to assess the association between pre-operative sepsis and 30-day mortality after hip fracture surgery. METHODS:We c...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aas.13160
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Multimodal analgesia is considered the leading principle for post-operative pain treatment, but no gold standard after total knee arthroplasty (TKA) exists. AIM:To investigate the beneficial and harmful effects of one or two doses of 24 mg intravenous dexamethasone (DXM) as part of a multimodal analgesic re...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aas.13481
更新日期：2020-02-01 00:00:00
abstract：:The effects of epinephrine as an adjuvant to local anesthetics were studied in the rat infraorbital nerve block (IONB) model, using solutions of 0.5% prilocaine, 0.5% mepivacaine, 0.125% bupivacaine or 0.125% ropivacaine in 50 mmol/l tris-hydroxymethylaminomethane (THAM) tested both without and with epinephrine (EPI) ...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1992.tb03486.x
更新日期：1992-07-01 00:00:00
abstract：BACKGROUND:Cyclosporine A has generated intense interest in the field of cardioprotection due to its ability to protect the mitochondria at reperfusion by blocking the opening of the mitochondrial permeability transition pore. The aim of our study was to examine the cardioprotective effect of Sandimmun, a clinically av...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.2010.02241.x
更新日期：2010-08-01 00:00:00
abstract：:This study compares the recovery from sufentanil and isoflurane anaesthesia in patients undergoing outpatient arthroscopy of the knee under general anaesthesia. In 40 unpremedicated patients, divided at random into two groups, anaesthesia was induced with methohexitone and vecuronium bromide and, after intubation, mai...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1399-6576.1987.tb02539.x
更新日期：1987-02-01 00:00:00
abstract：BACKGROUND:We examined the hypothesis that the minimum alveolar concentration of desflurane for maintaining bispectral index (BIS) below 50 (MACBIS 50 ) decreases with advance of age. METHODS:Sixty young (20-30 year), middle-aged (31-65 year) and elderly (66-80 year) patients were included (n = 20, each group). Five m...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aas.12642
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Bloodless field is an integral part of orthopedic surgery. Use of tourniquet is associated with a risk of skeletal muscle ischemia and reperfusion injury. The purpose of this prospective, open-randomized study was to determine if the use of a tourniquet system using low pressure, with a wide, curved cuff con...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1399-6576.1998.tb05135.x
更新日期：1998-04-01 00:00:00
abstract：BACKGROUND:Patients with complex regional pain syndrome (CRPS) are seen and treated by a variety of physicians. The present study aims to describe referral and treatment patterns for CRPS patients in the Netherlands. METHODS:Patients, who were selected (1996-2005) from an electronic general practice (GP) database (Int...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.2009.01927.x
更新日期：2009-07-01 00:00:00
abstract：BACKGROUND:Increased sympathetic activity perioperatively and associated cardiovascular effects play a central role in cardiovascular complications. High thoracic epidural blockade attenuates the sympathetic response, but even with complete pain relief, haemodynamic and endocrine responses are still present. Beta-adren...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1399-6576.1997.tb04652.x
更新日期：1997-11-01 00:00:00
abstract：:General anaesthesia influences the cardiovascular system at different levels. To increase our knowledge of how sympathetic outflow is affected by anaesthetic interventions, we used direct microelectrode recordings of muscle sympathetic activity (MSA) in the peroneal nerve in 18 patients scheduled for ENT-surgery. Duri...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1992.tb03478.x
更新日期：1992-05-01 00:00:00
abstract：BACKGROUND:A propofol target-controlled infusion (TCI) is often proposed for the management of difficult airway intubation and fibreoptic intubation under anaesthesia and spontaneous ventilation. No data are available about sevoflurane. The aim of the present study was to compare propofol and sevoflurane as hypnotics d...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1399-6576.2006.01186.x
更新日期：2007-01-01 00:00:00
abstract：:Intrathecal sufentanil can provide labor analgesia. We investigated the efficacy of multiple injections and the maternal and neonatal effects of intrathecal sufentanil during labor. Seventeen healthy women in active labor received multiple injections of intrathecal sufentanil of 5 micrograms each through microspinal c...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1996.tb04421.x
更新日期：1996-02-01 00:00:00
abstract：:Forty patients who underwent elective cholecystectomy were examined preoperatively and during the first postoperative week by physical examination, measurement of FVC and FEV1, arterial pH and blood gas analyses, and chest x-ray. Postoperative pulmonary complications (p.p.c.) were detected in 30 (75%) of the patients....
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1977.tb01211.x
更新日期：1977-01-01 00:00:00
abstract：:Two cases of middle-ear injury, due to sharp fluctuations of intratympanic pressure as a result of general anaesthesia with nitrous oxide are presented. A study is reported indicating that the degree of these fluctuations is a function of the concentration of nitrous oxide. In order to reduce the risk of middle-ear in...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1980.tb01539.x
更新日期：1980-06-01 00:00:00
abstract：:The importance of serum cholinesterase activity in burned patients was evaluated in relation to anaesthesia. Anaesthesia included a repeated administration of suxamethonium. Thirty-two patients with an estimated area of burn between 3 and 72% were studied during 39 anaesthetic procedures. A statistically significant i...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1399-6576.1975.tb05237.x
更新日期：1975-01-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to examine the effects of an intraoperative MgSO4 infusion on arterial oxygenation and lung mechanics in patients with moderate COPD undergoing cancer larynx surgery under general anesthesia (GA). Our primary outcome was arterial oxygenation determined by the PaO2 and PaO2 /FiO2...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aas.13684
更新日期：2020-11-01 00:00:00
abstract：:In the developed world, an increasing number of patients receive therapy with vitamin K antagonists (VKA). This group of patients poses an additional challenge in the perioperative management of emergency surgery and trauma. The present review offers a detailed description of some treatment options for reversal of VKA...
journal_title：Acta anaesthesiologica Scandinavica
pub_type： 杂志文章,评审
doi：10.1111/j.1399-6576.2011.02414.x
更新日期：2011-05-01 00:00:00
