Imprinted Small RNAs Unraveled: Maternal MicroRNAs Antagonize a Paternal-Genome-Driven Gene Expression Network.

Abstract:

:Whipple et al., 2020 describe that, in neurons, a dense cluster of maternally expressed microRNAs post-transcriptionally downregulates several imprinted genes expressed from the paternal genome-an antagonistic mechanism that modulates neuronal functions and provides insights into the evolution of genomic imprinting.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Ghousein A,Feil R

doi

10.1016/j.molcel.2020.03.019

subject

Has Abstract

pub_date

2020-04-02 00:00:00

pages

3-5

issue

1

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(20)30187-8

journal_volume

78

pub_type

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