Abstract:
:A variety of benign liver tumors associated with the use of oral contraceptives has been described. However, there is controversy regarding the possible relation of focal nodular hyperplasia of the liver to oral contraceptive therapy. Over a ten-year period at the Soroka Medical Center, two young women were found to have hepatic tumors diagnosed as focal nodular hyperplasia. In both cases the hepatic nodules were an incidental finding at laparotomy and were thought to be metastatic tumors. The clinical and pathological findings in both cases are reported. The features of focal nodular hyperplasia and its possible relation to oral contraceptive use is discussed. :The controversy concerning the possible relation of focal nodular hyperplasia (FNH) of the liver to oral contraceptives (OCs) continues. Sex steroids, such as estrogen, affect the liver more than any other organ outside of the genital organs. Research shows that in 10-40% of women taking OCs the bile secreting function of hepatocytes is impaired. Even though most liver cell adenomas in young women have been associated with OC use, this has not necessarily been the case for FNH. In addition, many studies demonstrate that FNH does not progress to become hepatic carcinoma, and FNH has never been fatal. Despite the fact that FNH mainly occurs in women, it has been present in newborn infants and in the elderly. Moreover, there is no evidence that using OCs increases the frequency of FNH. 2 cases of FNH at a medical center in Beer-Sheva, Israel only add to this controversy. A 21 year old, unmarried woman had been taking OCs 4 years prior to her arrival at the hospital. Complaining of 2 weeks of pain in the left chest and in the left upper quadrant of the abdomen and upon completion of a physical exam, surgery was performed and revealed a primary Ewing's sarcoma of the bone marrow of her lower left ribs. The liver appeared normal except for a 3x2x2 cm FNH on the anterior surface of the left lobe. She died 1 month later from respiratory arrest. A 32 year old woman who did not use OCs indicated pain for 6 hours in the left lower quadrant of the abdomen. Practitioners found the left Fallopian tube and ovary gangrenous and twisted. In addition, they found multiple FNHs on the liver. A total hysterectomy, bilateral salpingo-ovariectomy, and a liver biopsy were performed. She recovered with no complications.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Hagay ZJ,Leiberman RJ,Katz M,Witznitzer Adoi
10.1007/BF00932273subject
Has Abstractpub_date
1988-01-01 00:00:00pages
231-4issue
4eissn
0932-0067issn
1432-0711journal_volume
243pub_type
杂志文章abstract::In spite of menstrual bleedings during premenopause FSH-concentration in blood increases significantly, however, without reaching post-menopausal amounts. Sometimes it is correlated with climacteric symptoms. FSH increases already 10 years before menopause, whereas LH does not change. Responsible for that is the parti...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/BF02417644
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:The incidence of ectopic pregnancy (EP) in the general population is 2%, whereas the EP rate following assisted reproductive technologies (ART) is between 2.1 and 11%. EP is also an adverse effect of tubal surgery with incidences up to 40% depending on the type, location, and severity of tubal disease and the s...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-2092-6
更新日期:2012-03-01 00:00:00
abstract::Plasma and erythrocyte zinc concentrations in 45 proteinuric pre-eclamptic Chinese women were measured. There was no difference in either the plasma or erythrocyte zinc concentration between pre-eclamptic patients with and without intrauterine growth retardation. There was no correlation between either plasma or eryth...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02389541
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Many studies have shown that changes in the weather affect health. In the field of obstetrics and gynecology, several events have been empirically shown to be related to the weather. Labor pain is controlled by the autonomic nervous system and various hormones, and is expected to be influenced by the weather...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0259-3
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:Colposcopy-directed biopsy is a cornerstone method for diagnosing cervical intraepithelial neoplasia. The aim of this study was to evaluate the accuracy of colposcopy-directed biopsy in comparison with definitive surgery. METHODS:The accuracy of colposcopy-directed biopsy was compared with the final histology ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4953-8
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:Although intravenous acetaminophen is commonly used for the management of postoperative pain, very limited evidence supports the usefulness of preoperative administration. The aim of this study was to determine the analgesic effect of preoperative acetaminophen on opioid consumption, pain scores, and side effec...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-011-1860-7
更新日期:2011-12-01 00:00:00
abstract::A thirty four year old woman with recurrent catamenial pneumothorax is described. Pleural endometriosis was suspected and cytologic examination of fluid drained from the right pleural cavity showed glandular cell clusters of probable endometrial origin. The patient received a long-acting GnRH agonist (Triptorelin-Arve...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF01314646
更新日期:1995-01-01 00:00:00
abstract::In this study, our aim was to compare the effects of metformin and gonadotropin releasing hormone (GnRH) analogues in clinical and hormonal parameters in women with polycystic ovary syndrome (PCOS). There were 50 women with PCOS who were included in our study and they were divided into two groups. In this randomized t...
journal_title:Archives of gynecology and obstetrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00404-002-0344-1
更新日期:2003-06-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and toxicity of angiogenesis inhibitors for the treatment of ovarian cancer patients, we conducted a meta-analysis of the published literature on this subject. METHODS:In this meta-analysis, we searched PubMed, EMBASE, Web of Science, and Cochrane Library databases for randomized contr...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-020-05865-z
更新日期:2020-11-21 00:00:00
abstract:AIM:Breast cancer 2, early onset (BRCA2) has been reported to be associated with familial breast and ovarian cancer. Several proteins interact with conserved regions of BRCA2, which play significant roles in DNA damage repair and centrosomal localization. This study was aimed to identify a novel protein, Wilms tumor 1 ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-016-4176-9
更新日期:2016-11-01 00:00:00
abstract::The objective of the study was to examine the teratogenic potential of surgery under anesthesia during pregnancy in the large population-based dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980-1994. An analysis of cases with congenital abnormalities and matched healthy controls was p...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s004040050221
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:The purpose of the current study was to determine whether or not the quadruple test for screening Down syndrome is an effective method to replace direct amniocentesis in pregnant women ≥ 35 years of age. METHODS:This study analyzed the screening performance of the quadruple test according to maternal age at de...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-2052-1
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:Non-gestational ovarian choriocarcinoma (NGOC) is a rare malignant germ cell tumor. Through literature review and cases collection, we aim to analyze prognostic factors for NGOC and summarize its clinicopathological characteristics to guide the individualized treatment. METHODS:We searched PubMed database, Coc...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-020-05502-9
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:To validate the prediction equation of the volume of fetal cerebellum by three-dimensional ultrasonography determined for Taiwan's population in Brazilian population. METHODS:A longitudinal prospective study was performed with 52 normal pregnant women between 20 and 32 weeks. The measurement of fetal cerebe...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0192-5
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of two routes of misoprostol (sublingual and vaginal) for cervical ripening before hysteroscopy. METHODS:One hundred and ten perimenopausal women who were referred to a tertiary hospital for surgical hysteroscopy enrolled in this double-blind randomized clinical trial. They were divide...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-012-2652-4
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:We tested the hypothesis that the application of intranasal oxytocin (8 IU) following intrauterine insemination (IUI) would increase pregnancy rates, without causing major side effects. METHODS:Randomized, double-blind, placebo-controlled pilot study: eighty-six couples with idiopathic infertility, polycystic ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-009-1284-9
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:In a series of publications, we had developed the concept that uterine adenomyosis and pelvic endometriosis as well as endometriotic lesions at distant sites of the body share a common pathophysiology with endometriosis constituting a secondary phenomenon. Uterine auto-traumatization and the initiation of the m...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3437-8
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:Case report of a rare combination of a trisomy 18 and 21 in a dizygotic twin pregnancy in a woman with a history of recurrent miscarriage, a neonatal death, no living offspring and Graves disease. METHODS:Case report and literature search. RESULTS:Only one other report in the literature of a combined trisom...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-007-0378-5
更新日期:2007-11-01 00:00:00
abstract:PURPOSE:Chemokines have been implicated in the pathological process of endometriosis. We compared the effects of peritoneal fluid obtained from patients with endometriosis (ePF) and controls without endometriosis (cPF) on the release of monocyte-specific CC chemokines such as monocyte chemotactic protein-1 (MCP-1), reg...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1583-1
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effect of postpartum counseling on postpartum contraceptive use. METHODS:One hundred and forty-three women who delivered between 1 January 2004 and 31 September 2004 and counseled about postpartum contraception were included in the study. The participants were interv...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0287-z
更新日期:2007-06-01 00:00:00
abstract:METHODS:The maternal and fetal outcomes of 55 pregnancies in 24 patients with pre-existing lupus nephritis (LN) were retrospectively analysed. The risk factors for poor fetal outcome were evaluated. The patients were divided into two groups. Patients in Group A had quiescent LN and those in Group B showed clinical evid...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-003-0574-x
更新日期:2005-03-01 00:00:00
abstract:PURPOSE:To evaluate the clinical outcomes after fresh transfer of blastocysts cultured from vitrified-thawed cleavage embryos (VTCE) compared with conventional frozen-thawed blastocysts transfer (FBT), or with the usual fresh blastocysts transfer (FRBT). METHODS:A total of 155 cycles undergoing fresh transfer of VTCE ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05236-3
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Polycystic ovarian syndrome (PCOS) is the most prevalent metabolic disorder in reproductive-age women. It is indeed a multifactorial condition evidenced by ovarian dysfunction, hyperandrogenaemia, infertility, hormonal imbalance and chronic anovulation. Experimental evidence infers that PCOS women are prone ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-020-05951-2
更新日期:2021-01-13 00:00:00
abstract:OBJECTIVE:Osseous metaplasia is a rare pathological entity that affects the uterus and usually appears following abortion, chronic endometritis, metabolic disorders or following LEEP excision of the cervix. CASE:Herein, we present the occurrence of osseous metaplasia in a 27-year-old patient with a history of an abort...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-007-0515-1
更新日期:2008-06-01 00:00:00
abstract::Tubal sterilization is one of the options chosen by the women who have completed their fertility. Although ectopic pregnancy after tubal sterilization is rare, all women undergoing this procedure should be informed about the risk of it. An ectopic pregnancy in a 36-year-old woman who had undergone tubal sterilization ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/pl00007502
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:To investigate the precipitating factors of heart failure (HF) and to investigate the maternal and neonatal outcomes in pregnant women with HF. METHODS:We reviewed the medical records of pregnant women with HF who were treated at West China Second University Hospital between September 2012 and September 2017. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05350-2
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Polymyositis (PM) is an idiopathic inflammatory myopathy. Occasionally, it may present as a paraneoplastic syndrome and it is strongly associated with ovarian and weakly with breast cancer. We present here a case of a 60-year-old patient with sequential breast and ovarian (second primary) carcinomas followed...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0307-z
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:To compare the clinical effect of emergency cervical cerclage and elective cervical cerclage on pregnancy outcome in the cervical-incompetent pregnant women. METHODS:Literature was searched from the databases of Pubmed, Embase and Google scholar. The fixed or random effects model was used to calculate pooled r...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,meta分析
doi:10.1007/s00404-017-4602-7
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The last 5 years' studies using next-generation sequencing provided evidences that many types of solid tumors present spatial and temporal genetic heterogeneity and are composed of multiple populations of genetically distinct subclones that evolve over time following a pattern of branched evolution. The evol...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-017-4292-1
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:Τo estimate the discrepancy rate between colposcopy, punch biopsy histology and surgical specimen histology as well as the positive (PPV) and negative predictive value (NPV) of colposcopic diagnosis for high-grade squamous intraepithelial lesions (HGSIL). METHODS:A prospective study was conducted during the pe...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4714-8
更新日期:2018-05-01 00:00:00