CSC Expert Consensus on Principles of Clinical Management of Patients With Severe Emergent Cardiovascular Diseases During the COVID-19 Epidemic.

abstract：BACKGROUND:Previous studies have shown that pericytes can differentiate into osteoblasts and form bone. This study investigated whether pericytes can also differentiate into chondrocytes and adipocytes. METHODS AND RESULTS:Reverse transcription-polymerase chain reaction demonstrated that pericytes express mRNA for the...

journal_title：Circulation

authors： Farrington-Rock C,Crofts NJ,Doherty MJ,Ashton BA,Griffin-Jones C,Canfield AE

更新日期：2004-10-12 00:00:00

abstract：BACKGROUND:Diabetes mellitus is a prevalent public health problem that affects about one-third of the US population and leads to serious vascular complications with increased risk for coronary artery disease. How bone marrow hematopoiesis contributes to diabetes mellitus complications is incompletely understood. We inv...

journal_title：Circulation

authors： Hoyer FF,Zhang X,Coppin E,Vasamsetti SB,Modugu G,Schloss MJ,Rohde D,McAlpine CS,Iwamoto Y,Libby P,Naxerova K,Swirski FK,Dutta P,Nahrendorf M

更新日期：2020-07-21 00:00:00

abstract：BACKGROUND:CD4+CD28null T cells are present in increased numbers in the peripheral blood of patients with acute coronary syndrome (ACS) compared with patients with chronic stable angina (CSA). The triggers of activation and expansion of these cells to date remain unclear. METHODS AND RESULTS:Twenty-one patients with A...

journal_title：Circulation

authors： Zal B,Kaski JC,Arno G,Akiyu JP,Xu Q,Cole D,Whelan M,Russell N,Madrigal JA,Dodi IA,Baboonian C

更新日期：2004-03-16 00:00:00

abstract：:High-density lipoprotein (HDL) cholesterol distributions were compared among 191 black and 1341 white males and 233 black and 1088 white females, ages 5-44 years, examined in five of the Lipid Research Clinic (LRC) population-based surveys. Mean HDL cholesterol was higher in blacks than whites in each 5-year age group...

journal_title：Circulation

authors： Tyroler HA,Glueck CJ,Christensen B,Kwiterovich PO Jr

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:There is a paucity of randomized trials regarding diagnostic testing in women with suspected coronary artery disease (CAD). It remains unclear whether the addition of myocardial perfusion imaging (MPI) to the standard ECG exercise treadmill test (ETT) provides incremental information to improve clinical deci...

journal_title：Circulation

authors： Shaw LJ,Mieres JH,Hendel RH,Boden WE,Gulati M,Veledar E,Hachamovitch R,Arrighi JA,Merz CN,Gibbons RJ,Wenger NK,Heller GV,WOMEN Trial Investigators.

更新日期：2011-09-13 00:00:00

abstract：BACKGROUND:Spontaneous transient outward potassium currents (STOCs) induce myogenic relaxation in small cerebral vessels. We found STOCs in human coronary artery vascular smooth muscle cells (VSMCs) and studied their regulation. METHODS AND RESULTS:K+ currents were recorded in human coronary VSMCs by current- and volt...

journal_title：Circulation

authors： Bychkov R,Gollasch M,Ried C,Luft FC,Haller H

更新日期：1997-01-21 00:00:00

abstract：:The dynamics of acute mitral regurgitation were studied in six open-chest dogs in whom a portion of the anterior leaflet was excised. Phasic mitral and aortic flows were measured electromagnetically and left ventricular filling volume, regurgitant volume (RV) and forward stroke volume (SV) were calculated. The systoli...

journal_title：Circulation

authors： Yoran C,Yellin EL,Becker RM,Gabbay S,Frater RW,Sonnenblick EH

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:In the Basel Antiarrhythmic Study of Infarct Survival trial, low-dose amiodarone improved 1-year survival in patients with asymptomatic complex ventricular arrhythmias persisting 2 weeks after myocardial infarction. To assess whether this beneficial effect persisted despite discontinuation of amiodarone afte...

journal_title：Circulation

authors： Pfisterer ME,Kiowski W,Brunner H,Burckhardt D,Burkart F

更新日期：1993-02-01 00:00:00

abstract：:The acute hemodynamic effects of dobutamine and nitroprusside were compared in 19 patients with low output cardiac failure. At dosage levels yielding similar increases in cardiac index (12 patients), nitroprusside resulted in significantly lower arterial systolic and wedge pressures and did not increase heart rate sug...

journal_title：Circulation

authors： Berkowitz C,McKeever L,Croke RP,Jacobs WR,Loeb HS,Gunnar RM

更新日期：1977-12-01 00:00:00

abstract：:The purpose of this investigation was to determine whether blood vessels could develop de novo between an extracardiac artery and a collateral-dependent zone of the heart and to quantify the nutritive blood flow afforded by the new vessels. We also adapted the preparation so that angiogenically active agents could be ...

journal_title：Circulation

authors： Unger EF,Sheffield CD,Epstein SE

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Vascular events during initial reperfusion after a period of hypothermic cardioplegic ischemia may play an important role in the recovery of mechanical function. Prior studies have shown (1) that dysfunction of the postischemic myocardium after normothermic ischemia can be ameliorated by vasodilation and (2)...

journal_title：Circulation

authors： Kawata H,Aoki M,Mayer JE Jr

更新日期：1993-11-01 00:00:00

abstract：:In a study of aerobically perfused rat hearts, the in situ photoactivation (530-590 nm) of rose bengal (a process that leads to the production of singlet oxygen and superoxide) has been shown to lead to the rapid development of electrocardiographic abnormalities and arrhythmias. With rose bengal concentrations of 1,00...

journal_title：Circulation

authors： Kusama Y,Bernier M,Hearse DJ

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Early risk assessment is important in patients with unstable coronary artery disease, ie, unstable angina or non-Q-wave myocardial infarction. Some previous small studies have indicated that patients with unstable angina and elevation of troponin T (tn-T) have worse short-term and long-term prognoses. In thi...

journal_title：Circulation

authors： Lindahl B,Venge P,Wallentin L

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Dysregulation of adipocyte-derived bioactive molecules plays an important role in the development of atherosclerosis. We previously reported that adiponectin, an adipocyte-specific plasma protein, accumulated in the injured artery from the plasma and suppressed endothelial inflammatory response and vascular ...

journal_title：Circulation

authors： Okamoto Y,Kihara S,Ouchi N,Nishida M,Arita Y,Kumada M,Ohashi K,Sakai N,Shimomura I,Kobayashi H,Terasaka N,Inaba T,Funahashi T,Matsuzawa Y

更新日期：2002-11-26 00:00:00

abstract：BACKGROUND:The metabolic syndrome is associated with increased angiotensin II activity, induction of a proinflammatory and oxidative state, and endothelial dysfunction. We evaluated the ability of irbesartan, an angiotensin receptor blocker, and lipoic acid, an antioxidant, to affect endothelial function and inflammati...

journal_title：Circulation

authors： Sola S,Mir MQ,Cheema FA,Khan-Merchant N,Menon RG,Parthasarathy S,Khan BV

更新日期：2005-01-25 00:00:00

abstract：BACKGROUND:β1-2-adrenergic receptors (AR) are key regulators of cardiac contractility and remodeling in response to catecholamines. β3-AR expression is enhanced in diseased human myocardium, but its impact on remodeling is unknown. METHODS AND RESULTS:Mice with cardiac myocyte-specific expression of human β3-AR (β3-TG...

journal_title：Circulation

authors： Belge C,Hammond J,Dubois-Deruy E,Manoury B,Hamelet J,Beauloye C,Markl A,Pouleur AC,Bertrand L,Esfahani H,Jnaoui K,Götz KR,Nikolaev VO,Vanderper A,Herijgers P,Lobysheva I,Iaccarino G,Hilfiker-Kleiner D,Tavernier G,La

更新日期：2014-01-28 00:00:00

abstract：BACKGROUND:HMG CoA reductase inhibitors (or statins), a new class of lipid-lowering compounds, have raised expectations for more widespread use than that of the older lipid-lowering drugs. Not only are they more effective in lowering LDL cholesterol, but they are better tolerated as well. No data exist concerning the e...

journal_title：Circulation

authors： Furberg CD,Adams HP Jr,Applegate WB,Byington RP,Espeland MA,Hartwell T,Hunninghake DB,Lefkowitz DS,Probstfield J,Riley WA

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:The incidence of perinatal morbidity arising from birth hypoxia or asphyxia has not changed significantly in recent years despite marked improvements in labor management. Perinatal mortality in these circumstances may therefore reflect antenatal compromise and subsequent alteration of the fetal capacity to r...

journal_title：Circulation

authors： Gardner DS,Fowden AL,Giussani DA

更新日期：2002-10-22 00:00:00

abstract：:The cause and associated pathophysiology of precordial ST-segment depression (ST decreases) during acute inferior myocardial infarction (IMI) are controversial. To investigate this problem, electrocardiographic findings in 48 consecutive patients with acute IMI were prospectively compared with results of coronary angi...

journal_title：Circulation

authors： Gibson RS,Crampton RS,Watson DD,Taylor GJ,Carabello BA,Holt ND,Beller GA

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:A growing body of evidence from animal studies supports the hypothesis that oxidative stress-mediated mechanisms play a central role in early atherogenesis. In contrast, clinical trials with antioxidant vitamins have not produced consistent results in humans with established atherosclerosis. METHODS AND RES...

journal_title：Circulation

authors： Cyrus T,Yao Y,Rokach J,Tang LX,Praticò D

更新日期：2003-02-04 00:00:00

abstract：BACKGROUND:Uncoupling protein 2 (UCP2) regulates the production of reactive oxygen species in macrophages. However, its role in atherosclerosis is unknown. METHODS AND RESULTS:Irradiated low-density lipoprotein receptor deficient mice (LDLR-/-) were transplanted with bone marrow from either UCP2 deficient mice (Ucp2-/...

journal_title：Circulation

authors： Blanc J,Alves-Guerra MC,Esposito B,Rousset S,Gourdy P,Ricquier D,Tedgui A,Miroux B,Mallat Z

更新日期：2003-01-28 00:00:00

abstract：BACKGROUND:N(omega)-nitro-L-arginine methyl ester (l-NAME) is widely used to inhibit endothelial synthesis of NO in vivo. However, it is controversial whether the long-term vascular effects of l-NAME are mediated primarily by inhibition of endothelial NO synthesis. We addressed this point in mice that are deficient in ...

journal_title：Circulation

authors： Suda O,Tsutsui M,Morishita T,Tanimoto A,Horiuchi M,Tasaki H,Huang PL,Sasaguri Y,Yanagihara N,Nakashima Y

更新日期：2002-09-24 00:00:00

abstract：BACKGROUND:This study was designed to investigate whether collagen type I degradation is altered in patients with essential hypertension and whether this alteration could be related to disturbances in the serum matrix metalloproteinase pathway of collagen degradation. A second aim of the study was to assess whether som...

journal_title：Circulation

authors： Laviades C,Varo N,Fernández J,Mayor G,Gil MJ,Monreal I,Díez J

更新日期：1998-08-11 00:00:00

abstract：BACKGROUND:The impact of misinterpretation of the ECG in patients with acute myocardial infarction (AMI) in the emergency department (ED) setting is not well known. Our goal was to assess the prevalence of the failure to identify high-risk ECG findings in ED patients with AMI and to determine whether this failure is as...

journal_title：Circulation

authors： Masoudi FA,Magid DJ,Vinson DR,Tricomi AJ,Lyons EE,Crounse L,Ho PM,Peterson PN,Rumsfeld JS,Emergency Department Quality in Myocardial Infarction Study Investigators.

更新日期：2006-10-10 00:00:00

abstract：:Data from 981 patients evaluated for ischemic heart disease with coronary angiography were reviewed to identify variables predictive of sudden death and duration from onset of symptoms to death. During the period of follow-up, 113 patients died. Of these deaths, 99 were classified as cardiovascular. Forty percent occu...

journal_title：Circulation

authors： Oberman A,Ray M,Turner ME,Barnes G,Grooms C

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:Fe2+ released from tissue iron stores may accelerate lipid peroxidation by virtue of its pro-oxidant properties and thus promote early atherogenesis. METHODS AND RESULTS:The present prospective survey addresses the potential association between serum ferritin concentrations and the 5-year progression of car...

journal_title：Circulation

authors： Kiechl S,Willeit J,Egger G,Poewe W,Oberhollenzer F

更新日期：1997-11-18 00:00:00

abstract：:We studied six patients who suffered from angina pectoris but had angiographically patent major coronary arteries. Two of the patients suffered also from congestive heart failure. Three patients had supraventricular tachyarrhythmias. Three patients had conduction disturbances. During coronary angiography the patients ...

journal_title：Circulation

authors： Mosseri M,Yarom R,Gotsman MS,Hasin Y

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:The development of selective atrial antiarrhythmic agents is a current strategy for suppression of atrial fibrillation (AF). METHODS AND RESULTS:Whole-cell patch clamp techniques were used to evaluate inactivation of peak sodium channel current (I(Na)) in myocytes isolated from canine atria and ventricles. ...

journal_title：Circulation

authors： Burashnikov A,Di Diego JM,Zygmunt AC,Belardinelli L,Antzelevitch C

更新日期：2007-09-25 00:00:00

abstract：BACKGROUND:Macrophage migration inhibitory factor (MIF), a cytokine that controls cell-mediated inflammatory responses, is upregulated in atherogenesis; however, its functional contribution to lesion development has not been evaluated. METHODS AND RESULTS:We studied the role of MIF on neointima lesion formation after ...

journal_title：Circulation

authors： Schober A,Bernhagen J,Thiele M,Zeiffer U,Knarren S,Roller M,Bucala R,Weber C

更新日期：2004-01-27 00:00:00

abstract：:Twenty-one patients with documented coronary atherosclerotic heart disease were studied to determine the effect of high dose oral isosorbide dinitrate (ISDN) on heart rate, blood pressure, and exercise time until angina pectoris. Patients were tested in two phases, initially with 0.4 mg of sublingual nitroglycerin and...

journal_title：Circulation

authors： Danahy DT,Burwell DT,Aronow WS,Prakash R

更新日期：1977-02-01 00:00:00