Germline mutations in cancer susceptibility genes: an overview for nurses.

Abstract:

OBJECTIVE:To provide an overview of hereditary cancer susceptibility genes and associated cancer risks. DATA SOURCES:Peer reviewed published research studies and review articles. CONCLUSIONS:Identifying deleterious mutations in cancer susceptibility genes allows for clarification of cancer risk in individual family members and risk-level appropriate screening, and risk management recommendations. Evolving knowledge of the role of germline mutations provides an unprecedented opportunity to reduce cancer incidence, morbidity, and morality. IMPLICATIONS FOR NURSING PRACTICE:To provide individuals/families with accurate cancer risk management information and guidance, oncology nurses must be familiar with scientific discoveries related to cancer susceptibility genes.

journal_name

Semin Oncol Nurs

authors

MacDonald DJ

doi

10.1016/j.soncn.2010.11.004

subject

Has Abstract

pub_date

2011-02-01 00:00:00

pages

21-33

issue

1

eissn

0749-2081

issn

1878-3449

pii

S0749-2081(10)00086-0

journal_volume

27

pub_type

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