Abstract:
OBJECTIVES:To determine whether the linear length of a positive margin (LLPM) in radical prostatectomy specimens is associated with the risk of biochemical recurrence (BCR). METHODS:A total of 294 patients with a positive margin in the radical prostatectomy specimen were assessed for the association between the LLPM and BCR (defined as a serum prostate-specific antigen level of ≥0.2 ng/mL) using a Cox proportional hazards regression model. The concordance index on multivariate analysis was calculated without the LLPM, with LLPM as a continuous variable, and with the LLPM as a binary variable (≤1 mm vs >1 mm). RESULTS:The mean LLPM was 3.90 mm (median 2.0, range 0.1-30.5). The LLPM was an independent prognostic factor for BCR (P < .05) on both univariate and multivariate analysis. The concordance index was 0.6802 when the LLPM was not included and was 0.6865 and 0.7189 when the latter was modeled as a binary and continuous variable, respectively. When the patients were stratified according to their pathologic stage, the LLPM was an independent prognostic factor for BCR in the 185 patients with Stage pT2 tumors but not in the 109 patients with Stage pT3 tumors. CONCLUSIONS:The LLPM in the radical prostatectomy specimen was an independent predictive factor for BCR in patients with a positive margin. This association was stronger for Stage pT2 tumors with a positive margin. Reporting the actual LLPM could improve the predictive accuracy of BCR in patients whose radical prostatectomies had positive margins. We advocate reporting LLPM in radical prostatectomy, particularly for pT2 tumors.
journal_name
Urologyjournal_title
Urologyauthors
Cao D,Humphrey PA,Gao F,Tao Y,Kibel ASdoi
10.1016/j.urology.2010.10.059subject
Has Abstractpub_date
2011-06-01 00:00:00pages
1409-14issue
6eissn
0090-4295issn
1527-9995pii
S0090-4295(10)02061-3journal_volume
77pub_type
杂志文章相关文献
UROLOGY文献大全abstract::Renal fungus balls are rare in the adult population. A case of asymptomatic renal pelvic fungus balls is presented, and several approaches to treatment are discussed. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(93)90244-5
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVES:To develop a method for assessing absolute renal function (as well as morphology) in children, using gamma camera imaging of intravenously injected technetium-99m (99mTc) dimercaptosuccinic acid (DMSA). METHODS:Forty-five children (ages 1 week to 10 years; mean, 2.0 years) were imaged using a planar techniq...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(99)80461-0
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:To present the results of a new technique for abdominoplasty in patients with the Prune Belly syndrome (PBS). METHODS:Since 1985, 46 children with PBS underwent surgical treatment that included urinary tract reconstruction (UTR), orchidopexy, and abdominoplasty. In 41 patients, we performed the abdominoplast...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2013.09.031
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:To evaluate lower urinary tract dysfunction (LUTD) based on questionnaire symptom scoring and ultrasound assessment of bladder wall thickness (BWT) in children with cerebral palsy (CP). METHODS:A total of 97 children with CP were enrolled in the study. The patients were either symptomatic or asymptomatic wi...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.04.005
更新日期:2010-10-01 00:00:00
abstract::Sarcomas are rare and account for approximately 1% of all malignancies. The subtype angiosarcoma is derived from vascular and lymphatic tissue and generally has a poor prognosis. Prior radiation therapy is a known risk factor for the development of angiosarcomas. We present what we believe to be the first case of an a...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.01.074
更新日期:2007-03-01 00:00:00
abstract::Primary tumors of the seminal vesicle are very rare. We reported a 35-year-old man with a rare primary diffuse large B-cell lymphoma of the seminal vesicles. By transrectal ultrasound (TRUS) imaging, ultrasonic elastography (UE), and computed tomography (CT) imaging, the tumor was defined to locate in seminal vesicles...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2011.01.032
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To prospectively test the hypothesis that end-fire transrectal ultrasound prostate biopsy probes have greater cancer detection rates than side-fire probes. Retrospective studies have suggested that such probes might have greater cancer detection rates. METHODS:The present prospective randomized multicenter t...
journal_title:Urology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.urology.2012.01.061
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To investigate the perception and value of virtual open houses for urology applicants in the COVID-19 era, since students can no longer attend subinternships and all interviews will be conducted virtually. METHODS:A Twitter survey was sent to 230 likely urology applicants connected through the UroResidency p...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2020.08.077
更新日期:2020-12-01 00:00:00
abstract::Lymphoepithelioma-like carcinoma is an undifferentiated epithelial tumor with a prominent lymphocytic infiltrate and is rarely seen in the upper urinary tract. Only 3 and 2 cases involving the ureter and renal pelvis, respectively, have been reported. We report the fourth documented case of lymphoepithelioma-like carc...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/j.urology.2005.05.038
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVES:To compare the biomechanical properties of allografts, autografts, and synthetic materials used in sling surgery using the Instron tensinometer. METHODS:The sling grafts we studied consisted of autologous tissues (dermis, rectus fascia, and vaginal mucosa), cadaver tissues (decellularized dermis and freeze-...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(01)01205-5
更新日期:2001-09-01 00:00:00
abstract::We report a case of bilateral struvite and matrix staghorn calculi in a quadriplegic man with severe upper and lower extremity contractures that prevented percutaneous nephrolithotomy. Bilateral ureteroscopic lithotripsy was performed but the "snowstorm" of particles and viscous matrix material prevented complete ston...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(98)00395-1
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVES:To test the delivery of prostaglandin E1 (PGE1) in novel transdermal liposomal formulations through foreskin and to determine whether there is a correlation between in vitro transdermal absorption and in vivo efficacy in patients with erectile dysfunction. METHODS:The in vitro transdermal absorption of PGE1...
journal_title:Urology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0090-4295(98)00299-4
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:To treat mild-to-moderate apical compartment prolapse while preserving the uterus, our extraperitoneal uterosacral ligament hysteropexy repair technique was developed. Hysterectomy for prolapse accounted for 13% of all benign hysterectomies, which is the third most common reason.1 Although concomitant hystere...
journal_title:Urology
pub_type:
doi:10.1016/j.urology.2020.02.026
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES:The present study was designed to determine the relationship between serum prostate-specific antigen (PSA) levels and prostatic epithelial volumes. METHODS:Forty-two men between the ages of 50 and 79 years of age with either an abnormal digital rectal examination (DRE) or a serum PSA level > 4 ng/dL underwe...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(94)80131-2
更新日期:1994-08-01 00:00:00
abstract:OBJECTIVES:Autologous fat has been used as a bulking implant material for stress urinary incontinence. There is considerable controversy as to the ultimate fate of the grafted fat. This study was conducted to determine the fate of autogenous fat implanted into the bladder of rats. METHODS:Two groups of adult female ra...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(98)00338-0
更新日期:1998-11-01 00:00:00
abstract:INTRODUCTION:To describe the technique of injecting Lipiodol in the submucosa of the urinary bladder wall as a novel modality to improve localization of muscle-invasive bladder tumors before image-guided radiation therapy. TECHNICAL CONSIDERATIONS:Eight patients underwent submucosal Lipiodol injections at transurethra...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2013.09.058
更新日期:2014-04-01 00:00:00
abstract::To plan the treatment of carcinoma of the bladder correctly accurate knowledge of the morphology and degree of infiltration of the tumor is essential. Double contrast cystography and polycystography are radiologic techniques that can provide such information. Hitherto, these two procedures have been performed separate...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(77)90201-1
更新日期:1977-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the time to stone-free status after shock wave lithotripsy (SWL) for ureteral stones. METHODS:Medical records of 387 patients with ureteral stones who have been treated were retrospectively reviewed. Exclusion criteria for this analysis included nonopaque stones, prior ureteric surgery, multiple ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.10.060
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVES:Prostate-specific antigen (PSA) based end points are commonly used to report outcomes after treatment for prostate cancer. This study examines the influence of follow-up length on biochemical control (bNED) rates. METHODS:We reviewed 437 patients with clinically localized prostate cancer treated with confor...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(99)00253-8
更新日期:1999-11-01 00:00:00
abstract::Angiomyolipoma is a benign renal tumor that tends to grow with time and can be associated with complications, such as hemorrhage and pain, requiring active intervention. Nephron-sparing surgery for sporadic renal angiomyolipomas offers preservation of renal function and is associated with acceptable complication and r...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2009.02.051
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:To demonstrate the substantial litigious risks associated with vasectomy, a common urologic procedure. We examined the risk factors and types of negligence involved in vasectomy cases that go to trial and their associated outcomes. METHODS:Using the Westlaw legal database, we searched all jury verdicts and s...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2019.05.035
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To report a new technique to reconstruct the abdominal wall at the site of the hernia with 2 separate layers of human acellular dermal matrix (hADM). Parastomal hernia is the most commonly encountered complication of ileal conduit urinary diversion, occurring at a rate of 5%-25%. Multiple methods of parastoma...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.05.003
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To collect and analyze quality-of-life (QOL) data from PROvenge Treatment and Early Cancer Treatment trial (PROTECT, NCT00779402), a phase III, randomized controlled trial of sipuleucel-T in patients with asymptomatic androgen-dependent prostate cancer. METHODS:Patients experiencing prostate-specific antigen...
journal_title:Urology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.urology.2013.04.049
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:Failure of the continence mechanism is the most common cause of unsatisfactory results and the need for revision in patients with continent cutaneous urinary diversion. We believed that incontinence in these patients could be eliminated or minimized by using the concept of leak point pressure intraoperativel...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(98)00335-5
更新日期:1998-11-01 00:00:00
abstract::The results of bacterial susceptibility testing in 2,413 urine specimens obtained from patients with urinary tract infections indicated that in a high percentage clinical response could be predicted without the need for antimicrobial sensitivity testing. Simply identifying the infecting organism will provide the clini...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(82)90622-7
更新日期:1982-05-01 00:00:00
abstract:OBJECTIVE:To survey variations in recommended initial management of newborn spina bifida (SB). METHODS:Members of an international pediatric urology ListServe and of the Pediatric Urology Nurse Specialists organization were surveyed on practice patterns for newborn SB. Pediatric urologists, nurse practitioners, and ph...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.08.003
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVES:To identify patient groups associated with a high probability of false positives in photodynamic diagnosis (PDD) of bladder cancer for which the use of highly specific optical instruments could be beneficial. METHODS:This study includes the data of 306 patients. Under white light and 5-aminolevulinic acid-i...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2009.04.095
更新日期:2009-10-01 00:00:00
abstract::Enterocystoplasty, to construct a functional and continent bladder in male patients following cystoprostatectomy, can be simplified and shortened by some modifications. Partial pubectomy will allow a precise and bloodless section of the membranous urethra preserving the external sphincter and a watertight anastomosis ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(86)90096-8
更新日期:1986-08-01 00:00:00
abstract::Acute calculus disease of the upper urinary tract was studied retrospectively (1974-1978) in San Francisco Chinese and Caucasians. The Chinese population of San Francisco represents approximately 10 per cent of the total population. Yet the incidence of upper tract calculus among Chinese was found to be about twice th...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(81)90419-2
更新日期:1981-08-01 00:00:00
abstract:OBJECTIVES:To better understand the role of specific macronutrients on the risk of benign prostatic hyperplasia (BPH), we used data from an Italian case-control study. Although BPH is extremely common among the elderly, its etiology-and, particularly, the role of diet and specific macronutrients-is still unclear. METH...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2006.01.007
更新日期:2006-06-01 00:00:00