Abstract：
OBJECTIVE:Hyperthyroidism is a group of diseases with many different etiologies and clinical manifestations. The most common causes include toxic multi-nodular goiter, Graves' disease and toxic adenoma. The prevalence of thyroid cancer developing in patients with hyperthyroidism has gradually increased in recent years. The aim of this study is to detect the incidental thyroid cancer rates in patients who have undergone a surgical operation due to hyperthyroidism, and to specify the patient groups in whom surgical treatment should come into the foreground. METHODS:A total of 591 patients, who had surgical excision of the thyroid due to hyperthyroidism between January 2007 and June 2017, were retrospectively analyzed. RESULTS:Of all the patients included in the study, 377 (63.7%) had multi-nodular goiter, 132 (22.3%) had Graves' disease, 55 (9.4%) had nodular Graves' disease, and 27 (4.6%) had toxic adenoma. Thyroid cancer was determined in 131 out of 591 patients (22.6%) who were operated. The most common histologic type was thyroid micropapillary carcinoma (65/131; 49.6%). The accompanying pathologies to thyroid cancer were as follows: Toxic multi-nodular goiter (89/131; 67.9%), nodular Graves' disease (24/131; 18.3%), Graves' disease (13/131; 9.9%) and toxic adenoma (5/131; 2.8%). DISCUSSION:Prevalence of cancer on a background of hyperthyroidism has gradually increased in recent years. It is not realistic to determine thyroid cancer prevalence only based on autopsy examinations. This rate significantly increases in the presence of nodule in clinical studies. Most of the carcinomas are microcarcinomas that do not have lymphovascular invasion and have very low lymph node metastasis. Thus, their treatment is still under debate. KEY WORDS:Hyperthyroidism Micropapillary Cancer, Thyroid cancer. :L’ipertiroidismo ha diverse eziologie e differenti manifestazioni cliniche. Le cause più comuni sono il gozzo multi- nodulare tossico, la malattia di Graves e l’adenoma tossico. La prevalenza del cancro alla tiroide che si sviluppa in pazienti con ipertiroidismo è gradualmente aumentata negli ultimi anni. Lo scopo di questo studio è di rilevare i tassi incidentali di cancro alla tiroide in pazienti che hanno subito un intervento chirurgico a causa di ipertiroidismo e di specificare i gruppi di pazienti in cui il trattamento chirurgico dovrebbe essere di primo approccio. La casistica studiata retrospettivamente riguarda 591 pazienti sottoposti ad escissione chirurgica della tiroide a causa di ipertiroidismo tra gennaio 2007 e giugno 2017. Di tutti i pazienti inclusi nello studio, 377 (63,7%) avevano gozzo multi-nodulare, 132 (22,3%) avevano la malattia di Graves, 55 (9,4%) avevano la malattia di Graves nodulare e 27 (4,6%) avevano un adenoma tossico. Il cancro della tiroide è stato individuato 131 sul totale dei pazienti analizzati (22,6%). Il tipo istologico più comune era il carcinoma micropapillare tiroideo (65/131, 49.6%) e le patologie associate al carcinoma tiroideo erano rispettivamente un gozzo multinodulare tossico (89/131; 67,9%), la malattia di Graves nodulare (24/131; 18,3%), la malattia di Graves (13/131; 9,9%) e l’adenoma tossico (5/131; 2,8%). La presenza del cancro su uno sfondo di ipertiroidismo è gradualmente aumentata negli ultimi anni, e non è realistico determinare l’incidenza del cancro tiroideo solo sulla base di esami di autopsia. Questo tasso aumenta significativamente in presenza di noduli negli studi clinici, e la maggior parte dei carcinomi sono microcarcinomi che non presentano invasione linfovascolare e con bassa incidenza di metastasi linfonodali. Pertanto, il loro trattamento è ancora in discussione.
journal_name
Ann Ital Chirjournal_title
Annali italiani di chirurgiaauthors
Aksoy SÖ,Sevinç Aİ,Durak MGsubject
Has Abstractpub_date
2020-01-01 00:00:00pages
16-22eissn
0003-469Xissn
2239-253Xpii
S0003469X20030250journal_volume
91pub_type
杂志文章abstract：:We have studied the levels of the MEGX test in a heterogeneous group of 50 patients with chronic liver disease and with hepatic tumours and we have compared it with the routine LFTS commonly used to assess liver function and with the Child-Pugh Classification system. Our results demonstrate a statistically significant...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:The authors report the results of a prospective study on 204 patients (1980-1993) affected by early infiltrating breast cancer (size pounds 2 cm) as a part of a surgical series of 608 cases. 53 cases who underwent QUART (25.9%) and 151 cases (74.1%) who underwent mastectomy modified according to Patey have been collec...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：:Endometriosis (E) is an estrogen-dependent inflammatory disorder that is observed in approximately 10% of women in childbearing age, and is the most common benign gynecological disorder requiring hospitalization. In 5% of cases, there is an involvement of the gastrointestinal tract, for the most part of the sigmoid co...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2012-07-01 00:00:00
abstract：AIM:We propose our experience in soft tissue reconstruction in Hemifacial microsomia using a free fascioadiposal flap. MATERIAL OF STUDY:Hemifacial microsomia (HFM) is a congenital disorder characterized by craniofacial malformation of one or both sides of the lower face. A 18-year-old female presented with hemifacial...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2017-01-01 00:00:00
abstract：:Melanoma is considered one of the most lethal cancers and surgical therapy of its pulmonary metastases is rarely indicated. The only hope for a successful surgical treatment of secondaries from melanoma is a radical resection. Considering the very frequent multiorgan involvement of melanoma metastases, surgery is usua...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：1998-07-01 00:00:00
abstract：:Severe bleeding may complicate the course of either acute or chronic pancreatitis, the latter being more frequently involved. Pseudocysts, severe inflammation, regional necrosis and infection may cause major vessel erosion with or without pseudoaneurysm formation which eventually may result in severe bleeding into the...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：1995-03-01 00:00:00
abstract：AIM:Cholecystectomy is among surgical procedures with the longest waiting list and a significant amount of patients waiting for surgery suffer from symptoms related to complications of cholelithiasis. The aim of this study is to evaluate the economic impact caused by waiting lists. MATERIAL AND METHODS:A retrospective...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2015-07-01 00:00:00
abstract：INTRODUCTION:Prognosis of colon cancer is worse if complications are present at the moment of diagnosis. The high mortality rate with surgery in emergency in such cases needs a careful reflection about the best suitable operation to perform. MATERIALS AND METHODS:107 consecutive patients observed along a 9 year-period...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：AIM:Early identification of spontaneous pneumomediastinum can be achieved by thoracic ultrasound in emergency. MATERIAL OF STUDY:A spontaneous pneumomediastinum in a 24 -year old man is reported. RESULTS:The patient, who refused hospitalization, returned 12 hours later, complaining a massive subcutaneous emphysema, w...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2012-01-01 00:00:00
abstract：:This case report describes an acute colonic diverticular perforation occurred to a multiple myeloma patient, taking corticosteroid and morphine therapy, revealed by a subcutaneous emphysema of upper chest and right abdomen as initial presentation. Sigmoid diverticulitis with perforation and generalized peritonitis is ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2002-11-01 00:00:00
abstract：AIM:Poland syndrome is a constellation of rare congenital anomalies of the chest wall, with or without alterations to the ipsilateral superior extremity. Actually Foucras' classification is commonly used to choose the most appropriate surgical treatment, but often only a radiological classification proves unsatisfactor...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2014-05-01 00:00:00
abstract：:A 76 year-old female patient with a long-time history of nonspecific abdominal pain admitted to our hospital. Imaging studies showed 5 cm liver hydatid cyst between segments 2 and 3. She was recommended surgery and was informed about the details of single incision laparoscopic surgery (SILS). We performed single-incis...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2013-07-01 00:00:00
abstract：:A case of non-functioning parathyroid cyst is reported, in which the preoperative diagnosis was missed. A careful review of the pertinent literature allows to outline the correct approach to this rare pathology as for the diagnosis and the treatment; as well, to enlight the current controversies about the physiopathol...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：INTRODUCTIONS:Thyroid cancer is the most common endocrine malignancy with an incidence equal to 1% of all malignant tumors. Prognostic factors affecting survival are manifold, including in several classifications (AMES, AGES, CORN and TNM). In this sense, the invasion of adjacent structures is one of the most important...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2012-11-01 00:00:00
abstract：:The authors report a case of chronic splenic tuberculosis. They underline the diagnostic difficulties, notwithstanding the remarkable progresses in radiological technics, essentially related to the rarity of this tubercular site and they outlined the exact surgical indication to the splenectomy. ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：BACKGROUND:Cervical carotid dissection is more common in extracranical vessel: internal carotid artery dissection (ICAD) is typical, vertebral artery dissection is uncommon, common carotid artery dissection (CCAD) is rare and even a more rare cause of ischemic stroke. Cervical artery dissections account up to 20-25% of...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-09-18 00:00:00
abstract：:The central venous catheterization (CVC) by subclavian vein puncture for total parenteral nutrition (TPN) has a high risk of complications in some situations such as neck or supraclavicular diseases, tracheostomies, costoclavicular deformities and coagulopathies. Surgical CVC approach to the basilic vein is indicated ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：:A case of acute colonic obstruction in an elderly patient is presented, with a brief discussion about peculiar aspects to pseudo-obstruction and particularly chronic idiopathic intestinal pseudo-obstruction (CIIP), in which it was classified by pathologists. Clinical and therapeutic implications of this classification...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2019-05-05 00:00:00
abstract：AIM:Recto-Urinary Fistula (RUF) is a rare complication of pelvic surgery. Different approaches are reported in literature but a gold standard treatment has not yet been achieved. Transanal Endoscopic Microsurgery (TEM) is a miniinvasive approach with well known advantages as magnification, 3D view and lighting of the o...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：:From the beginning of the 60s, Japanese Lung Cancer Society (JLCS) proposed an original TNM classification of lung cancer based on a database of resected cases. The final step was the UICC classification edited in 1973. Complete hilar-mediastinal lymph node dissection was started in the same era and the concept of sta...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
abstract：UNLABELLED:Recent advances in preoperative localisation of parathyroid adenomas and intraoperative prove of complete removal of hyperfunctioning parathyroid tissue have fostered less invasive operative procedures which directly target the diseased gland. Such strategies have partially replaced the previous gold standar...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:Exclusive abdominal nodal involvement due to Hodgkin or non Hodgkin lymphoma (HL,NHL) is a rare condition, but its occurrence requires a good enough specimen for diagnosis and therapy. Aim of this work is to evaluate the results of laparoscopic lymph node biopsy (LLNB) in a series of patients where a primiti...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:Since discovered in 1990, Cag A, a protein expressed by specific strains of Helicobacter pylori, was thought able to explain why only a few Helicobacter infected patients develop peptic diseases and gastric cancer. However, clinical trials provide discordant results. MATERIALS AND METHODS:In this study we e...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2002-11-01 00:00:00
abstract：:Hepatic metastases are a major cause of death in patients with colorectal carcinoma. Traditional intravenous chemotherapy produces responses in 10% to 30% of patients and surgical resection is feasible in approximately 20% of patients. Infusion of cytotoxic agents into the hepatic artery is the most promising form of ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：1996-11-01 00:00:00
abstract：OBJECTIVES:Acute hypercalcemia is a serious condition and represents a physician-surgical emergency: the difficulty in setting a precise diagnosis is due to several possibilities that can cause the condition. It is our purpose to critically evaluate the most actual schemes of treatment and the conditions that could fav...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：:Breast cancer is a rare, but frequently hidden pathology. A woman, 36 years old, during the early months of pregnancy found a little tumor in her right breast. A fine needle biopsy was negative for cancer. Despite this, the tumor rose and two months after delivery (the patient breast-fed her daughter for a month), she...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：:The nonparasitic cysts of the spleen are uncommon and their pathogenesis has not been precisely determined. Often asymptomatic, the cysts are recognised during an investigation of the abdomen for other pathological conditions; if present, the symptoms are not specific and mild. The authors report two cases of non para...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：1998-07-01 00:00:00
abstract：AIM:Many methods have been described for the reconstruction of the lower lip, but each has its own advantages and its disadvantages. The purpose of this study is to evaluate the results obtained with the use of different methods in order to choose the most appropriate method, according to the characteristics of the los...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2012-07-01 00:00:00
abstract：:Thrombosed haemorrhoids and anal haematomas are very usual in patients with haemorrhoids. Conservative treatment and surgery are effective by the features and time of presentation. Authors refer about pathological and clinical findings and discuss the treatment. ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：1995-11-01 00:00:00
abstract：:Blunt colorectal traumas are rare clinical entities with a challenging diagnostic and operative management. We describe the case of a 40-year-old man, victim of an accidental fall from a height of four meters who was subsequently diagnosed to have a blunt rectal trauma. A first CT scan showed fracture of the skull and...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2016-12-20 00:00:00
