Epidermolysis bullosa nevus-like lesions in a pediatric patient with pyoderma gangrenosum.

Abstract:

:Epidermolysis bullosa-associated nevi are recently described dysplastic nevi found in patients with epidermolysis bullosa. These lesions display clinical features of unusual nevi suggestive of malignancy but thus far cases with malignant transformation have not been reported. We describe a case of epidermolysis bullosa-type nevi developing in a child with pyoderma gangrenosum. The nevi in our patient were found in areas previously affected by pyoderma gangrenosum and were clinically concerning for malignancy. However, they were only moderately atypical on light and confocal microscopy. This case demonstrates that pediatric patients with cutaneous inflammation, bullae formation, or both, are at risk for developing unusual nevi at previous sites of skin involvement. Considering the absence of malignant change in these nevi, we suggest that close observation can be employed in cases where this diagnosis can be confirmed both clinically and microscopically.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Mollet T,Henderson FW,Groben PA,Burkhart CN,Morrell DS

doi

10.1111/j.1525-1470.2010.01353.x

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

32-4

issue

1

eissn

0736-8046

issn

1525-1470

journal_volume

28

pub_type

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