Natural variability and correlations in the metabolic profile of healthy Eisenia fetida earthworms observed using ¹H NMR metabolomics.

Abstract:

:¹H NMR metabolomics can be used to assess the sub-lethal toxicity of contaminants to earthworms by identifying alterations in the metabolic profiles of contaminant- exposed earthworms in contrast to those of healthy (control) individuals. In support of this method this study sought to better characterize the baseline metabolic profile of healthy, mature earthworms of the species, Eisenia fetida, which is recommended for both acute and sub-lethal toxicity testing for soil contaminants. Profiles of D(2)O-buffer extracted metabolites were determined using (1)H NMR spectroscopy and both inter-individual metabolic variability and pair-wise metabolic correlations were assessed. The control earthworm extracts exhibited low overall inter-individual metabolic variability, with a spectrum-wide median relative standard deviation (%RSD=standard deviation/mean×100) of 14%, which suggests that the metabolic profile of E. fetida earthworms is well controlled in laboratory conditions and supports further use of this organism in environmental metabolomics research. In addition, strong positive correlations were detected between the levels of maltose, betaine, glycine, and glutamate as well as between the levels of lactate, valine, leucine, alanine, lysine, tyrosine, and phenylalanine which had not previously been reported. Since comparison of pair-wise metabolic correlations between control and treated organisms can reveal changes in the underlying pattern of biochemical relationships between the metabolites, identification of these significant metabolic correlations in control earthworms provides an additional characteristic that may be applied to delineate between control and treated earthworms in future NMR-based metabolomic studies.

journal_name

Chemosphere

journal_title

Chemosphere

authors

Whitfield Slund M,Celejewski M,Lankadurai BP,Simpson AJ,Simpson MJ

doi

10.1016/j.chemosphere.2011.01.036

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

1096-101

issue

8

eissn

0045-6535

issn

1879-1298

pii

S0045-6535(11)00052-X

journal_volume

83

pub_type

杂志文章
  • Leaching of veterinary antibiotics in calcareous Chinese croplands.

    abstract::Veterinary antibiotics reach the soil environment by manure application, where they accumulate or are prone to vertical translocation. We assumed that a high pH value at slightly calcareous soil properties should retain tetracyclines and fluoroquinolones even at high manure loads, whereas it should facilitate leaching...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2013.01.110

    authors: Ostermann A,Siemens J,Welp G,Xue Q,Lin X,Liu X,Amelung W

    更新日期:2013-05-01 00:00:00

  • Bioaccumulation and lack of toxicity of octachlorodibenzofuran (OCDF) and octachlorodibenzo-p-dioxin (OCDD) to early-life stages of zebra fish (Brachydanio rerio).

    abstract::Previous studies with octachlorodibenzo-p-dioxin (OCDD) and octachlorodibenzofuran (OCDF) in juvenile or adult fish exposed via water revealed no toxicity, despite significant bioaccumulation. With 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD), the fish early-life stage study has been shown to be the most sensiti...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/s0045-6535(97)00129-x

    authors: Berends AG,Boelhouwers EJ,Thus JL,de Gerlache J,de Rooij CG

    更新日期:1997-08-01 00:00:00

  • Insight into efficient removal of Cr(VI) by magnetite immobilized with Lysinibacillus sp. JLT12: Mechanism and performance.

    abstract::In this work, Lysinibacillus sp. JLT12 was used to remove the Cr(VI)-induced passive layer on the magnetite. Mechanism study via dynamic kinetics, X-ray diffraction, Raman spectroscopy, and X-ray photoelectron spectroscopy analyses revealed that Lysinibacillus sp. JLT12 could remove the passive layer (lepidocrocite an...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2020.127901

    authors: Zhu Y,He X,Xu J,Fu Z,Wu S,Ni J,Hu B

    更新日期:2021-01-01 00:00:00

  • Diesel oil volatilization processes affected by selected porous media.

    abstract::Volatilization plays an important role in attenuating petroleum products in contaminated soils. The objective of this study was to evaluate the influence of wind speed, vessel diameter and mean grain size of porous media on diesel oil volatilization. Experiments were conducted to investigate the volatilization behavio...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2013.10.073

    authors: Ma Y,Zheng X,Anderson SH,Lu J,Feng X

    更新日期:2014-03-01 00:00:00

  • Dynamics of selected pre-existing polybrominated diphenylethers (PBDEs) in municipal wastewater sludge under anaerobic conditions.

    abstract::Despite the rapid, widespread accumulation of polybrominated diphenylethers (PBDEs) in our surroundings, their environmental fate has been largely unknown. In the present study, most common congeners (BDE 47, 99, 100, 138, 153, 154, 183 and 209) were investigated for their dynamics in municipal sewage sludge under mes...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2009.12.057

    authors: Shin M,Duncan B,Seto P,Falletta P,Lee DY

    更新日期:2010-03-01 00:00:00

  • Ultrathin reduced graphene oxide/MOF nanofiltration membrane with improved purification performance at low pressure.

    abstract::Here we demonstrated an alternative partial reduction graphene oxide/metal-organic frameworks nano-scale laminated membrane for dyes and heavy metal ions removal at low pressure. Compared with pure prGO membranes, the novel UiO-66-(COOH)2/prGO membranes with loose structure and excellent selective permeability demonst...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2018.04.064

    authors: Zhang P,Gong JL,Zeng GM,Song B,Liu HY,Huan SY,Li J

    更新日期:2018-08-01 00:00:00

  • Effects of copper(II) and copper oxides on THMs formation in copper pipe.

    abstract::Little is known about how the growth of trihalomethanes (THMs) in drinking water is affected in copper pipe. The formation of THMs and chlorine consumption in copper pipe under stagnant flow conditions were investigated. Experiments for the same water held in glass bottles were performed for comparison. Results showed...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2007.01.082

    authors: Li B,Qu J,Liu H,Hu C

    更新日期:2007-08-01 00:00:00

  • Synthesis of Na-A zeolite from Jeju Island scoria using fusion/hydrothermal method.

    abstract::Na-A zeolite (Z-S1) was synthesized from scoria found on Jeju Island, Korea using the fusion/hydrothermal method. The influences of NaOH/scoria ratio, SiO2/Al2O3 molar ratio, and particle sizes on the synthesis of zeolite were studied by analyzing crystals morphology and crystallinity. According to XRD analysis, it wa...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2018.05.080

    authors: Lee MG,Park JW,Kam SK,Lee CH

    更新日期:2018-09-01 00:00:00

  • Effects of hexavalent chromium on intestinal histology and microbiota in Bufo gargarizans tadpoles.

    abstract::Chromium is detrimental heavy metal pollutants and can enter and affect aquatic organisms. In our experiment, B. gargarizans embryos were chronically exposed in different concentrations of Cr (VI) (0, 13, 104, and 416 μg Cr6+ L-1) until reached Gosner stage 38. We measured morphological parameters of the body and inte...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2018.10.147

    authors: Yao Q,Yang H,Wang X,Wang H

    更新日期:2019-02-01 00:00:00

  • Effects analysis of substituent characteristics and solvents on the photodegradation of polybrominated diphenyl ethers.

    abstract::The ultraviolet spectra and electron transition information of 209 polybrominated diphenyl ethers (PBDEs) in gas were first calculated via time-dependent density functional theory using Gaussian 09 software. The main and second-order interactional effects of substituent characteristics on the photodegradation of PBDEs...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2017.07.063

    authors: Jiang L,Qiu Y,Li Y

    更新日期:2017-10-01 00:00:00

  • Cupressus macrocarpa leaves for biomonitoring the environmental impact of an industrial complex: The case of Puchuncaví-Ventanas in Chile.

    abstract::The Punchuncaví Valley is one of the most polluted areas in central Chile affected by anthropogenic emissions from the Ventanas Industrial Complex (IC) where the most important industry is the copper smelter and refinery. In this context, this research aims were to assess the usefulness of the Cupressus macrocarpa as ...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2020.127521

    authors: Gorena T,Fadic X,Cereceda-Balic F

    更新日期:2020-12-01 00:00:00

  • Metal internalization by bacterial cells depends on metal biotoxicity and metal to biomass ratio.

    abstract::The traditional view of metal adsorption to bacterial surfaces is that it can act as a protective mechanism by externalizing the metal outside the cell. However, numerous studies focussing on the biodynamics of metal uptake using biotic ligand models consider metal adsorption to cell surfaces as an important first ste...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2018.08.125

    authors: Liang L,Ngwenya BT

    更新日期:2018-12-01 00:00:00

  • Peroxymonosulfate activation by hydroxylamine-drinking water treatment residuals for the degradation of atrazine.

    abstract::Drinking water treatment residuals (WTRs) have been applied in organic pollutants degradation in water by generating reactive oxygen species from peroxymonosulfate (PMS), however, the slow transformation of Fe(III) to Fe(II) may limit its widespread application. Hydroxylamine (HA) was introduced into the system to enh...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2019.02.186

    authors: Zhang H,Liu X,Lin C,Li X,Zhou Z,Fan G,Ma J

    更新日期:2019-06-01 00:00:00

  • Phytoremediation of anatoxin-a by aquatic macrophyte Lemna trisulca L.

    abstract::The neurotoxin anatoxin-a (ANTX-a), one of the most common cyanotoxin, poses a health risk to people and can be lethal to aquatic organisms. This paper presents results on its bioremediation by the aquatic macrophyte Lemna trisulca. We show that the plant is resistant to the harmful impact of toxin and is capable of r...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2014.04.064

    authors: Kaminski A,Bober B,Chrapusta E,Bialczyk J

    更新日期:2014-10-01 00:00:00

  • Cytotoxic, genotoxic and mutagenic effects of sewage sludge on Allium cepa.

    abstract::The objective of this study was to ascertain the cytotoxic, genotoxic and mutagenic potential of sewage sludge using Allium cepa bioassay. Solubilized and crude sludge from two sewage treatment stations (STSs), herein named JM and M, were tested. In addition, sanitized, crude and solubilized sludge were also analyzed ...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2016.01.071

    authors: Corrêa Martins MN,de Souza VV,da Silva Souza T

    更新日期:2016-04-01 00:00:00

  • Personal level exposure and hazard potential of particulate matter during haze and non-haze periods in Singapore.

    abstract::Severe haze episodes originating from biomass burning are common in Southeast Asia. However, there is a paucity of data on the personal exposure and characteristics of Particulate Matter (PM) present in ambient air during haze and non-haze periods. Aims of this study were to monitor 24 h ambulatory exposure to PM amon...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2019.125401

    authors: George S,Chua ML,ZheWei DZ,Das R,Bijin VA,Connolly JE,Lee KP,Yung CF,Teoh OH,Thomas B

    更新日期:2020-03-01 00:00:00

  • Designing monitoring networks to represent outdoor human exposure.

    abstract::Measurements of outdoor human exposure to suspended particulate matter (PM) are always constrained by available resources. An effective network design requires tradeoffs between variables measured, the number of sampling locations, sample duration, and sampling frequency. Sampling sites are needed to represent neighbo...

    journal_title:Chemosphere

    pub_type: 杂志文章,评审

    doi:10.1016/s0045-6535(02)00239-4

    authors: Chow JC,Engelbrecht JP,Watson JG,Wilson WE,Frank NH,Zhu T

    更新日期:2002-12-01 00:00:00

  • Inoculation of Bacillus spp. Modulate the soil bacterial communities and available nutrients in the rhizosphere of vetiver plant irrigated with acid mine drainage.

    abstract::Acid mine drainage (AMD) is one of an important pollution sources associated with mining activities and often inhibits plant growth. Plant growth promoting bacteria has received extensive attention for enhancing adaptability of plants growing in AMD polluted soils. The present study investigated the effect of plant gr...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2020.128345

    authors: Daraz U,Li Y,Sun Q,Zhang M,Ahmad I

    更新日期:2021-01-01 00:00:00

  • Demonstration of a consensus approach for the calculation of physicochemical properties required for environmental fate assessments.

    abstract::Eight software applications are compared for their performance in estimating the octanol-water partition coefficient (Kow), melting point, vapor pressure and water solubility for a dataset of polychlorinated biphenyls, polybrominated diphenyl ethers, polychlorinated dibenzodioxins, and polycyclic aromatic hydrocarbons...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2017.11.137

    authors: Tebes-Stevens C,Patel JM,Koopmans M,Olmstead J,Hilal SH,Pope N,Weber EJ,Wolfe K

    更新日期:2018-03-01 00:00:00

  • Determination and identification of metabolites of the fungicides Iprodione and Procymidone in compost.

    abstract::The main metabolites formed from Iprodione and Procymidone during the composting process have been isolated and identified by HPLC-DAD-MSD. After addition of the fungicides to the composting pile, we monitored the reaction of the two analytes and the formation of their degradation products for eight months. We verifie...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/s0045-6535(99)00555-x

    authors: Vanni A,Gamberini R,Calabria A,Nappi P

    更新日期:2000-11-01 00:00:00

  • Phytoremediation potential of a novel fern, Salvinia cucullata, Roxb. Ex Bory, to pulp and paper mill effluent: Physiological and anatomical response.

    abstract::The study was conducted with an aim to remediate effluent from a pulp and paper mill, after treating it for 28 days with an aquatic fern, Salvinia cucullata. The effluent had high BOD, COD, TS, TSS, TDS, P, hardness and chloride, and several heavy metals (Cd, Cu, Cr, Ni, Pb, Mg, Mn, Fe and Zn) above national limits. H...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2016.08.013

    authors: Das S,Mazumdar K

    更新日期:2016-11-01 00:00:00

  • Effect of chromium species on phytochemical and physiological parameters in Datura innoxia.

    abstract::In soil, chromium can be found in two main valence states: hexavalent Cr(VI) and trivalent Cr(III). In this study, we investigated the impact of Cr on photosynthetic gas exchange, photosystem II (PSII) activity, Cr translocation and accumulation, proline content and alkaloids production, i.e. scopolamine and hyoscyami...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2008.03.018

    authors: Vernay P,Gauthier-Moussard C,Jean L,Bordas F,Faure O,Ledoigt G,Hitmi A

    更新日期:2008-06-01 00:00:00

  • Influences of coagulation pretreatment on the characteristics of crude oil electric desalting wastewaters.

    abstract::Highly polluted crude oil electric desalting wastewaters (EDWs) severely affect the efficiency of refinery wastewater treatment plants (WWTPs). Coagulation is an efficient pretreatment to reduce the impacts of EDWs. In the present study, the influences of coagulation pretreatment on the characteristics of EDWs of thre...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2020.128531

    authors: Ye H,Chen L,Kou Y,How ZT,Chelme-Ayala P,Wang Q,An Z,Guo S,Chen C,Gamal El-Din M

    更新日期:2021-02-01 00:00:00

  • Cadmium down-regulates 11β-HSD2 expression and elevates active glucocorticoid level via PERK/p-eIF2α pathway in placental trophoblasts.

    abstract::Fetal overexposure to active glucocorticoid (GC) is the major cause for fetal growth restriction (FGR). This study investigated the influences of cadmium (Cd) exposure on active GC and its mechanism in placental trophoblasts. Pregnant mice were exposed to CdCl2 (4.5 mg/kg, i.p.). Human JEG-3 cells were treated with Cd...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2020.126785

    authors: Shi XT,Zhu HL,Xiong YW,Liu WB,Zhou GX,Cao XL,Yi SJ,Dai LM,Zhang C,Gao L,Xu DX,Wang H

    更新日期:2020-09-01 00:00:00

  • Occurrence and removal of selected micropollutants in a water treatment plant.

    abstract::The levels of 14 micropollutants including nine pharmaceuticals, two pesticides, and three endocrine disruptors were measured in a water treatment plant (WTP) in Seoul, Korea. Among the measured micropollutants, 12 (excluding atrazine and triclocarban) were found in the influent and effluent from the WTP, at levels ra...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2013.08.055

    authors: Nam SW,Jo BI,Yoon Y,Zoh KD

    更新日期:2014-01-01 00:00:00

  • Adsorption kinetics of magnetic biochar derived from peanut hull on removal of Cr (VI) from aqueous solution: Effects of production conditions and particle size.

    abstract::Magnetic biochar was made from peanut hull biomass using iron chloride in a simplified aqueous phase approach and pyrolysis at alternative peak temperatures (450-650 °C). Magnetic biochar showed an extreme capacity for adsorption of hexavalent chromium Cr (VI) from aqueous solution, which was 1-2 orders of magnitude h...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2015.11.050

    authors: Han Y,Cao X,Ouyang X,Sohi SP,Chen J

    更新日期:2016-02-01 00:00:00

  • Radical/radical vs radical/molecule reactions in the formation of PCDD/Fs from (chloro)phenols in incinerators.

    abstract::Pathways from chlorinated phenols as precursors to PCDD/Fs are discussed with focus on the effect of (poly)chlorination on thermochemistry and rate in the displacement of chlorine from a chlorophenol molecule by a (chloro)phenoxy radical (reaction (A) as a key example). Through measurements on the respective methyleth...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/s0045-6535(01)00272-7

    authors: Louw R,Ahonkhai SI

    更新日期:2002-03-01 00:00:00

  • A metabolomics study: CdTe/ZnS quantum dots induce polarization in mice microglia.

    abstract::In this study, a metabolomic analysis was used to reveal the neurotoxicity of the CdTe/ZnS QDs via microglia polarization. A gas chromatography-mass spectrometer (GC-MS) was applied to uncover the metabonomic changes in microglia (BV-2 cell line) after exposure to 1.25 μM CdTe/ZnS QDs. 11 annotated metabolic pathways ...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2019.125629

    authors: He K,Liang X,Wei T,Liu N,Wang Y,Zou L,Bai C,Yao Y,Wu T,Kong L,Zhang T,Xue Y,Tang M

    更新日期:2020-05-01 00:00:00

  • Genetic susceptibility to dioxin-like chemicals' induction of cytochrome P4501A2 in the human adult linked to specific AhRR polymorphism.

    abstract:BACKGROUND:Dioxin-like chemicals are known to exert their effect by binding to aryl hydrocarbon receptor (AhR), forming complexes with aryl hydrocarbon nuclear translocator (ARNT), and binding to dioxin responsive elements (DREs) in promoter region to regulate the transcription of specific genes. In a previous study of...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2012.10.026

    authors: Hung WT,Lambert GH,Huang PW,Patterson DG Jr,Guo YL

    更新日期:2013-03-01 00:00:00

  • S-triazine residues in groundwater.

    abstract::In the last years, the occurrence of pesticides and other chemicals in groundwater has been confirmed. The herbicide atrazine is among the pesticides most frequently detected in groundwater. In groundwater samples from the United States atrazine concentrations reached levels up to 10 micrograms/1. In our lysimeter exp...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/s0045-6535(97)00142-2

    authors: Dörfler U,Feicht EA,Scheunert I

    更新日期:1997-07-01 00:00:00