Cigarette demand and delayed reward discounting in nicotine-dependent individuals with schizophrenia and controls: an initial study.

abstract：:The effects of bromocriptine, lisuride and apomorphine on specific binding of 3H-spiroperidol to homogenates of rat caudate nucleus were studied. (+)-Butaclamol was used to define specific binding. Bromocriptine and lisuride inhibited binding markedly, in vitro and also 30 min after in vivo injection. Bromocriptine co...

journal_title：Psychopharmacology

authors： Weir RL,Hruska RE,Silbergeld EK

更新日期：1981-01-01 00:00:00

abstract：RATIONALE:Understanding factors contributing to individual differences in vulnerability to opioid addiction is essential for developing more effective preventions and treatments, yet few reliable behavioral predictors of subsequent opioid self-administration have been identified in rodents. Sensitivity to the acute eff...

journal_title：Psychopharmacology

authors： Swain Y,Muelken P,Skansberg A,Lanzdorf D,Haave Z,LeSage MG,Gewirtz JC,Harris AC

更新日期：2020-08-01 00:00:00

abstract：:We have previously obtained evidence that the mesoamygdaloid dopamine projection modulates the acquisition of a conditioned response (CR) elicited by presentation of a conditioned stimulus (CS) predicting the availability of a natural (sucrose) reward. This property was found to be dependent upon D3, but not D1 or D2,...

journal_title：Psychopharmacology

authors： Hitchcott PK,Phillips GD

更新日期：1998-12-01 00:00:00

abstract：RATIONALE:The extent to which non-α4β2 versus α4β2* nAChRs contribute to the behavioral effects of varenicline and other nAChR agonists is unclear. OBJECTIVES:The purpose of this study was to characterize the discriminative stimulus effects of varenicline and nicotine using various nAChR agonists and antagonists to el...

journal_title：Psychopharmacology

authors： de Moura FB,McMahon LR

更新日期：2017-03-01 00:00:00

abstract：:Psychopharmacological studies using caffeinated beverages or caffeine have rarely considered temporal effects on psychological and physiological function or the specific contribution of caffeine, hot water, or beverage type to the observed effects. The effect of 400 ml hot tea, coffee, and water consumption on systoli...

journal_title：Psychopharmacology

authors： Quinlan P,Lane J,Aspinall L

更新日期：1997-11-01 00:00:00

abstract：RATIONALE:Nicotine and other agonists of nicotinic cholinergic receptors (nAChR) have been shown to improve performance in specific memory domains in rodents and monkeys. Such beneficial effects are observed in preclinical models of age-related cognitive decline, stimulating interest in nAChR ligands as possible therap...

journal_title：Psychopharmacology

authors： Katner SN,Davis SA,Kirsten AJ,Taffe MA

更新日期：2004-09-01 00:00:00

abstract：:Administration of drugs that reduce the influence of dopamine at its receptor site can lead to postsynaptic supersensitivity, whereas treatment with dopamine (DA) agonists can cause postsynaptic subsensitivity. Both unaltered and enhanced postsynaptic responses to DA have been shown after pretreatment with DA agonists...

journal_title：Psychopharmacology

authors： Castro R,Abreu P,Calzadilla CH,Rodriguez M

更新日期：1985-01-01 00:00:00

abstract：:Two experiments were conducted to study the effects of anxiogenic drugs on dopamine release and metabolism in nucleus accumbens. Microdialysis probes were implanted into the nucleus accumbens, and rats were tested the day after implantation. In the first experiment, groups of rats received injections of saline, 1.25 o...

journal_title：Psychopharmacology

authors： McCullough LD,Salamone JD

更新日期：1992-01-01 00:00:00

abstract：:Shaking movements of the body, similar to that made by a dog when wet ('wet-dog shakes'), occur in rats in response to pharmacological stimuli and in response to stimuli associated with cold and skin irritation. In this study, shaking movements, elicited by a variety of stimuli, were inhibited by central administratio...

journal_title：Psychopharmacology

authors： Wei ET

更新日期：1983-01-01 00:00:00

abstract：:The effects of meperidine on operant behavioral thermoregulation were investigated using a convective thermal controller and mice trained to alternate at will the thermal-drive condition, changing it from an air flow of 15 degrees C to one of 45 degrees C, and vice versa. Administration of 15 mg/kg meperidine resulted...

journal_title：Psychopharmacology

authors： Gessner PK,Clarke CC

更新日期：1979-09-01 00:00:00

abstract：INTRODUCTION:Understanding an individual's vulnerability to drug addiction has important implications for the development of effective personal treatment plans. Although theories acknowledge impulsive behaviour as a key component of drug addiction, little is known about the influence of trait impulsivity on an individu...

journal_title：Psychopharmacology

authors： Kolokotroni KZ,Rodgers RJ,Harrison AA

更新日期：2014-02-01 00:00:00

abstract：RATIONALE:Although both contain behaviourally significant concentrations of caffeine, tea is commonly perceived to be a less stimulating drink than coffee. At least part of the explanation for this may be that theanine, which is present in tea but not coffee, has relaxing effects. There is also some evidence that thean...

journal_title：Psychopharmacology

authors： Rogers PJ,Smith JE,Heatherley SV,Pleydell-Pearce CW

更新日期：2008-01-01 00:00:00

abstract：:Both muscarinic antagonists, such as scopolamine, and benzodiazepine receptor (BZR) agonists, such as diazepam, produce a reliable impairment in the performance of one trial passive avoidance. Such deficits are frequently interpreted as drug-induced amnesia. However, these deficits could also result from a learning im...

journal_title：Psychopharmacology

authors： Cole BJ,Jones GH

更新日期：1995-03-01 00:00:00

abstract：RATIONALE:The majority of pharmacotherapies proposed for cocaine dependence have been marginally effective and frequently have undesirable side effects. We recently demonstrated that short-term treatment with citicoline decreased self-reported desire to use cocaine in crack cocaine users. OBJECTIVE:The present study w...

journal_title：Psychopharmacology

authors： Lukas SE,Kouri EM,Rhee C,Madrid A,Renshaw PF

更新日期：2001-09-01 00:00:00

abstract：:Two putative predictors of placebo response were studied in three samples of psychiatric outpatients. Two groups, 73 university medical center patients and 56 college health service patients, underwent 1 week of placebo treatment. A quasi-control group of 112 patients receiving no medication waited about 1 week before...

journal_title：Psychopharmacology

authors： McNair DM,Gardos G,Haskell DS,Fisher S

更新日期：1979-06-21 00:00:00

abstract：:The effects of single and repeated electroconvulsive treatment (ECT) on beta-endorphin (beta-EP), cortisol, growth hormone (GH) and prolactin (Prl) plasma levels were investigated in nine depressed patients. Blood samples were monitored a day before ECT, the day of the first and sixth ECT (0, 30, 60 and 90 min after s...

journal_title：Psychopharmacology

authors： Weizman A,Gil-Ad I,Grupper D,Tyano S,Laron Z

更新日期：1987-01-01 00:00:00

abstract：:Three-hour sessions of differential reinforcement of low-rate behavior (DRL 45-s) in rats were used to investigate alprazolam, caffeine, and their interactions at the onset, peak and disappearance of serum alprazolam, while caffeine level remained constant. The dose-response curve (DRC) method of Pöch permitted an ext...

journal_title：Psychopharmacology

authors： Lau CE,Wang J

更新日期：1996-07-01 00:00:00

abstract：RATIONALE:Pediatric bipolar disorder (PBD) is a chronic and debilitating psychiatric illness. It is associated with many short-term and long-term complications including poor academic and social performance, legal problems and increased risk of suicide. Moreover, it is often complicated by other serious psychiatric dis...

journal_title：Psychopharmacology

authors： Smarty S,Findling RL

更新日期：2007-03-01 00:00:00

abstract：RATIONALE:Perphenazine, a classical antipsychotic drug, has the potential to induce extrapyramidal side effects (EPS). Dopaminergic and serotonergic pathways are involved in the therapeutic and adverse effects of the drug. OBJECTIVES:To evaluate the impact of polymorphisms in the dopamine D(2) and D(3) and serotonin 2...

journal_title：Psychopharmacology

authors： Gunes A,Scordo MG,Jaanson P,Dahl ML

更新日期：2007-03-01 00:00:00

abstract：:The name of Hayley Treloar Padovano was incorrectly tagged in the original version of this article. Instead of Padovano as family name and Hayley Treloar as given name, it should be Hayley as given name and Treloar Padovano as family name. Correct presentation of author name when online should be Treloar Padovano H. ...

journal_title：Psychopharmacology

authors： Mereish EH,Treloar Padovano H,Wemm S,Miranda R Jr

更新日期：2018-09-01 00:00:00

abstract：:The effect of diazepam on spatial visualization was studied using a double-blind crossover design. Diazepam 10 mg (or placebo) was given orally to 12 healthy young men at bedtime, followed again by 10 mg (or placebo) the next morning. One hour after the administration of the morning dose, the subjects performed a ment...

journal_title：Psychopharmacology

authors： Taylor J,Hunt E,Coggan P

更新日期：1987-01-01 00:00:00

abstract：:This research compares the effects, in mice and rats, of desmethylclomipramine (DCLOM) and clomipramine (CLOM). DCLOM antagonized the hypothermia induced in mice by reserpine or apomorphine to a much greater extent than CLOM. Reserpine ptosis in mice was depressed by DCLOM only. Similarly, only DCLOM was effective in ...

journal_title：Psychopharmacology

authors： Maj J,Stala L,Górka Z,Adamus A

更新日期：1982-01-01 00:00:00

abstract：:Postsynaptic dopamine-cholecystokinin (CCK) interactions in the nucleus accumbens were studied in two behavioral preparations of DA receptor supersensitivity: chronic-neuroleptic treated and 6-hydroxydopamine (6-OHDA) denervated rats. Subcutaneous (SC) injections of apomorphine (APO; 0.15 mg/kg) in experiment 1 produc...

journal_title：Psychopharmacology

authors： Weiss F,Ettenberg A,Koob GF

更新日期：1989-01-01 00:00:00

abstract：RATIONALE:Acute cocaine administration produces an initial rewarding state followed by a dysphoric/anxiogenic "crash." OBJECTIVE:The objective of this study was to determine whether individual differences in the relative value of cocaine's positive and negative effects would account for variations in subsequent drug s...

journal_title：Psychopharmacology

authors： Ettenberg A,Fomenko V,Kaganovsky K,Shelton K,Wenzel JM

更新日期：2015-07-01 00:00:00

abstract：RATIONALE:Pramipexole is a dopamine agonist which binds selectively to dopamine D(3) and D(2) receptors. There is evidence that, in addition to its beneficial effects in parkinsonism, this compound may also be of value in addressing symptomatology associated with depressive diseases. OBJECTIVES:The present study was a...

journal_title：Psychopharmacology

authors： Lehr E

更新日期：2002-10-01 00:00:00

abstract：RATIONALE:Somatostatin and its receptors have been localized in brain nuclei implicated in motor control, such as the striatum, nucleus accumbens, ventral pallidum, and globus pallidus (GP). OBJECTIVES:The objective of this study was to investigate the role of somatostatin receptors (sst(1,2,4)) in the GP on dopamine ...

journal_title：Psychopharmacology

authors： Marazioti A,Pitychoutis PM,Papadopoulou-Daifoti Z,Spyraki C,Thermos K

更新日期：2008-12-01 00:00:00

abstract：:To test the Pavlovian conditioning model of alcohol tolerance, two groups of eight male social drinkers each received five administrations of alcohol and five administrations of an equal volume of tonic each, on an alternating basis, during the initial 10-session tolerance development phase of the study. Group 1 recei...

journal_title：Psychopharmacology

authors： Shapiro AP,Nathan PE

更新日期：1986-01-01 00:00:00

abstract：:Depression in children is currently an area of considerable controversy, as is the use of potent psychopharmacologic agents in children. Since EEG sleep techniques have proven to be useful in understanding the mechanisms of depression in adults and in predicting their response to antidepressants, a pilot study employi...

journal_title：Psychopharmacology

authors： Kupfer DJ,Coble P,Kane J,Petti T,Conners CK

更新日期：1979-01-31 00:00:00

abstract：RATIONALE:Beneficial effects of nicotine on cognitive processes including attention have potential therapeutic uses and have been proposed as incentives for tobacco smoking. OBJECTIVES:To establish task conditions under which the effects of nicotine on attention are obtained reliably and to characterise such effects f...

journal_title：Psychopharmacology

authors： Hahn B,Shoaib M,Stolerman IP

更新日期：2002-07-01 00:00:00

abstract：RATIONALE:Recent studies have suggested that the salutary actions of clozapine in schizophrenia may be due to selective activation of M(1) muscarinic receptors by clozapine and/or its major active metabolite N-desmethylclozapine. OBJECTIVE:We systematically tested this hypothesis by screening a large number of psychoa...

journal_title：Psychopharmacology

authors： Davies MA,Compton-Toth BA,Hufeisen SJ,Meltzer HY,Roth BL

更新日期：2005-04-01 00:00:00