Abstract:
OBJECTIVE:To test the feasibility of non-contrast magnetic resonance imaging (MRI) in a sequential imaging study for characterizing computed tomography (CT)-detected arterial-enhancing nodules that do not washout in patients at risk of hepatocellular carcinoma (HCC). MATERIALS AND METHODS:In this retrospective study, 134 patients (mean age ± standard deviation, 56.8 ± 10.0 years) with 151 arterial enhancing-only nodules measuring up to 2 cm during multiphasic CT that were subsequently evaluated using gadoxetic acid-enhanced MRI in treatment-naïve at-risk patients from three tertiary referral centers were included. Tentative diagnostic criteria for HCC and hepatic malignancy were defined as the presence of one of eight MRI features favoring HCC in combinations of the following sequences: T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), T1-weighted dual gradient-echo in-phase and out-of-phase imaging (Dual-GRE), and hepatobiliary phase imaging (HBP). Typical hemangiomas and arterioportal shunts were excluded from the analysis. Diagnostic performance for HCC and hepatic malignancy was calculated and compared between the abbreviated MRI and full-sequence gadoxetic acid-enhanced MRI. RESULTS:Of 151 nodules (mean size, 1.2 cm) 68 HCCs and 83 non-HCC benignities and malignancies were included. The combination of T2WI, DWI, and Dual-GRE showed per-lesion sensitivity, specificity, and accuracy of 88.2%, 90.4%, and 89.4%, respectively, comparable to those of full-sequence MRI. Applying the same sequence combination to diagnose hepatic malignancy had per-lesion sensitivity, specificity, and accuracy of 86.8%, 97.3%, and 92.1%. In nodules < 1 cm, adding HBP increased sensitivity by up to 13% without compromising the specificity or accuracy. CONCLUSION:The non-contrast MRI protocol comprising T2WI, DWI, and Dual-GRE showed reasonable and comparable performance to full-sequence MRI for discriminating HCC and primary liver malignancies in CT-detected indeterminate arterial enhancing-only nodules in at-risk patients, and can be potentially used for sequential imaging in place of a full-sequence MRI. In nodules < 1 cm, HBP may still be needed to preserve sensitivity.
journal_name
Korean J Radioljournal_title
Korean journal of radiologyauthors
Park SH,Kim B,Kim SY,Choi SJ,Huh J,Kim HJ,Kim KW,Lee SSdoi
10.3348/kjr.2019.0447subject
Has Abstractpub_date
2020-03-01 00:00:00pages
280-289issue
3eissn
1229-6929issn
2005-8330pii
21.280journal_volume
21pub_type
杂志文章abstract:OBJECTIVE:This study was designed to develop an automated system for quantification of various regional disease patterns of diffuse lung diseases as depicted on high-resolution computed tomography (HRCT) and to compare the performance of the automated system with human readers. MATERIALS AND METHODS:A total of 600 cir...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2009.10.5.455
更新日期:2009-09-01 00:00:00
abstract::Holoprosencephaly (HPE) and polycystic kidney disease (PKD) are genetically heterogeneous anomalies which can make up part of various syndromes or chromosomal anomalies. Due to the rapid lethality prognosis, early and precise prenatal diagnosis would be of great value. This case report describes extensive PKD involvem...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2009.10.3.307
更新日期:2009-05-01 00:00:00
abstract::The use of computed tomography (CT) in emergency departments has increased over several decades, as physicians increasingly depend on imaging for diagnoses. Patients and medical personnel are put at risk due to frequent exposure to and higher levels of radiation, with very little evidence of improvements in outcomes. ...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2018.0416
更新日期:2019-03-01 00:00:00
abstract::A tumoral pseudoangiomatous stromal hyperplasia (PASH) that causes huge breast enlargement is very rare. Only two cases of huge tumoral PASHs have been reported in the English medical literature. We report here on a surgically confirmed case of bilateral huge tumoral PASH in a 47-year-old woman, and we present the ima...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2010.11.3.355
更新日期:2010-05-01 00:00:00
abstract::In order to relieve mechanical obstruction caused by rectal carcinoma, a bare rectal stent was inserted in the sigmoid colon of a 70-year-old female. The procedure was successful, and for one month the patient made good progress. She then complained of abdominal pain, however, and plain radiographs of the chest and ab...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2000.1.3.169
更新日期:2000-07-01 00:00:00
abstract:Objective:To investigate the technical safety and clinical efficacy of a double-stent system with long duodenal extension in patients with malignant extrahepatic biliary obstruction. Materials and Methods:This prospective study enrolled 48 consecutive patients (31 men, 17 women; mean age, 61 years; age range, 31-77 ye...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2018.19.2.230
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate the diagnostic value of combining the quantitative parameters of shear wave elastography (SWE) and superb microvascular imaging (SMI) to breast ultrasound (US) to differentiate between benign and malignant breast masses. MATERIALS AND METHODS:A total of 200 pathologically confirm...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2019.0765
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:We evaluated the association between patients' weight and abdominal cross-sectional dimensions and CT image quality. MATERIALS AND METHODS:We prospectively evaluated 39 cancer patients aged more than 65 years with multislice CT scan of abdomen. All patients underwent equilibrium phase contrast-enhanced abdom...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2003.4.4.234
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To compare the effect of radio frequency ablation (RFA) on the dimensions of radio frequency coagulation necrosis in a rabbit lung using a wet electrode in monopolar mode with that in dual electrode bipolar mode at different infusion rates (15 mm/hr versus 30 ml/hr) and saline concentrations (0.9% normal vers...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2006.7.2.97
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:To compare conventional sensitivity encoding (SENSE) to compressed sensing plus SENSE (CS) for high-resolution magnetic resonance imaging (HR-MRI) of intracranial and extracranial arteries. MATERIALS AND METHODS:HR-MRI was performed in 14 healthy volunteers. Three-dimensional T1-weighted imaging (T1WI) and p...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2018.0424
更新日期:2019-03-01 00:00:00
abstract::The management of gastrointestinal stromal tumors (GISTs) has evolved significantly in the last two decades due to better understanding of their biologic behavior as well as development of molecular targeted therapies. GISTs with exon 11 mutation respond to imatinib whereas GISTs with exon 9 or succinate dehydrogenase...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2017.18.1.84
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the feasibility of CT fluoroscopy (CTF)-guided percutaneous transhepatic biliary drainage (PTBD) in emergency patients with acute obstructive cholangitis. MATERIALS AND METHODS:The study included 28 patients admitted to the emergency center due to obstructive jaundice and found to require urgent ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2009.10.2.144
更新日期:2009-03-01 00:00:00
abstract::(11)C-methionine (Met) positron emission tomography (PET) is one of the most commonly used PET tracers for evaluating brain tumors. However, few reports have described tips and pitfalls of (11)C-Met PET for general practitioners. Physiological (11)C-Met uptake, anatomical variations, vascular disorders, non-tumorous l...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2016.17.3.424
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To investigate whether there is a relationship between texture analysis parameters of apparent diffusion coefficient (ADC) maps and histopathologic features of MCF-7 and MDA-MB-231 xenograft models. MATERIALS AND METHODS:MCF-7 estradiol (+), MCF-7 estradiol (-), and MDA-MB-231 xenograft models were made with...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2014.15.5.591
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:Using a pulsating coronary artery phantom at high heart rate settings, we investigated the efficacy of a motion correction algorithm (MCA) to improve the image quality in dual-energy spectral coronary CT angiography (CCTA). MATERIALS AND METHODS:Coronary flow phantoms were scanned at heart rates of 60-100 be...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2017.18.6.881
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:This study aimed to assess the surgical morbidity and mortality of thoracic endovascular repair (TEVAR) as compared with open surgical repair (OSR) for isolated descending thoracic aortic disease. MATERIALS AND METHODS:From January 1, 2006 through May 31, 2010, a total of 68 patients with isolated descending...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2012.13.4.476
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the upgrade rate and delayed false-negative results of percutaneous vacuum-assisted removal (VAR) and surgical excision in women with imaging-histologic discordance during ultrasound (US)-guided automated core needle biopsy (CNB) of the breast and to validate the role of VAR as a rebiopsy method f...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2014.15.6.697
更新日期:2014-11-01 00:00:00
abstract::Over the last few years, percutaneous radiofrequency (RF) ablation has been successfully established as a viable treatment modality for small peripheral renal cell carcinoma (RCC). This technique is limited by central tumor location and tumor size. We report the interventional management of a 5.3 cm mixed RCC with cen...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2009.10.5.523
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To assess magnetic resonance imaging (MRI) features of coronary microembolization in a swine model induced by small-sized microemboli, which may cause microinfarcts invisible to the naked eye. MATERIALS AND METHODS:Eleven pigs underwent intracoronary injection of small-sized microspheres (42 µm) and catheter...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2016.17.1.83
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To assess the performance of diffusion tensor imaging (DTI) for the diagnosis of cervical spondylotic myelopathy (CSM) in patients with deformed spinal cord but otherwise unremarkable conventional magnetic resonance imaging (MRI) findings. MATERIALS AND METHODS:A total of 33 patients who underwent MRI of the...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2015.16.6.1303
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:The purpose of the current study was to develop support vector machine (SVM) and artificial neural network (ANN) models for the pre-operative prediction of advanced prostate cancer by using the parameters acquired from transrectal ultrasound (TRUS)-guided prostate biopsies, and to compare the accuracies betwe...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2011.12.5.588
更新日期:2011-09-01 00:00:00
abstract::Percutaneous interventional procedures under image guidance, such as biopsy, ethanol injection therapy, and radiofrequency ablation play important roles in the management of hepatocellular carcinomas. Although uncommon, the procedures may result in tumor implantation along the needle tract, which is a major delayed co...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2008.9.3.268
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To record the MR imaging features of primary central nervous system lymphoma (PCNSL) and compare these features in monofocal and multifocal disease. MATERIALS AND METHODS:Twenty-one cases of monofocal disease were compared to five cases of multifocal disease. All patients were examined by non-enhanced and co...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2010.11.3.269
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and clinical efficacy of transcatheter uterine artery embolization (UAE) for post-myomectomy hemorrhage. MATERIALS AND METHODS:We identified eight female patients (age ranged from 29 to 51 years and with a median age of 37) in two regional hospitals who suffered from post-myomectomy he...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2014.15.3.356
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:To assess the relationship between apparent diffusion coefficient (ADC) values on diffusion-weighted magnetic resonance (MR) imaging and pathologic measures of a tumor using a prostate cancer xenograft model. MATERIALS AND METHODS:Eighteen athymic nude mice with 36 PC-3-induced tumors were sacrificed to obta...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2012.13.1.82
更新日期:2012-01-01 00:00:00
abstract::Recently, sarcopenia has garnered renewed interest. Sarcopenia is a disease characterized by decreased skeletal muscle mass and strength/function, which can impair the quality of life and increase physical disability, adverse metabolic effects, and mortality. Imaging tools for evaluating and diagnosing sarcopenia have...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2018.0479
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the clinical efficacy as well as long-term clinical outcomes of superselective microcoil embolization for lower gastrointestinal bleeding (LGIB). MATERIALS AND METHODS:Between 1997 and 2009, 26 patients with intended transcatheter embolotherapy for LGIB were retrospectively reviewed. Embolization...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2013.14.2.259
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:To determine histopathologic findings related to the indeterminate or inadequate result of fine-needle aspiration biopsy (FNAB) in papillary thyroid carcinomas (PTCs) and to correlate histopathological findings with ultrasonographic features of tumors. MATERIALS AND METHODS:We retrospectively reviewed the me...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2010.11.2.141
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy of Mangafodipir trisodium (Mn-DPDP)-enhanced MR cholangiogrphy (MRC) and Gadobenate dimeglumine (Gd-BOPTA)-enhanced MRC in visualizing a non-dilated biliary system. MATERIALS AND METHODS:Eighty-eight healthy liver donor candidates underwent contrast-enhanced T1-weighted MRC. Mn-DPDP a...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2005.6.4.229
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the findings of brain MRI in patients with carbon disulfide poisoning. MATERIALS AND METHODS:Ninety-one patients who had suffered carbon disulfide poisoning [male:female=87:4; age, 32-74 (mean 53.3) years] were included in this study. To determine the extent of white matter hyperintensity (Grade ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2002.3.3.158
更新日期:2002-07-01 00:00:00