Abstract:
BACKGROUND:Negative events in childhood are associated with increased risk of mental health problems, and evaluation could help identify students at high risk of mental health disorder. However, childhood adversity measures are difficult to implement in routine care. Perceived parental support in childhood and adolescence may be more easily assessed, as it is a rather neutral and non-intrusive question. METHODS:We retrieved students' health data collected from the French i-Share cohort, in a longitudinal population-based study including 4463 students of 18-24 years of age. Students in this cohort completed a self-reported questionnaire about major psychiatric problems at one-year follow-up. RESULTS:Among 4463 participants, 26% reported a major mental health problem-including suicidal behavior (17%), major depression (7%), and severe generalized anxiety disorder (15%). Adjusted logistic regression revealed that a lower level of perceived parental support was significantly associated with higher risk of any mental health problem. Compared to students who reported extremely strong perceived parental support, students who perceived no support had a nearly 4-fold higher risk of mental health problems (aOR 3.80, CI 2.81-5.13). Lower levels of perceived parental support were dose-dependently associated with higher incidences of suicidal behavior, major depression, and severe generalized anxiety disorder. LIMITATIONS:Study limitations included a moderate follow-up response rate, and retrospective self-report questionnaires. CONCLUSION:Perceived parental support was strongly associated with the incidence of mental health problems among college students. If validated, these results suggest that health professionals should consider using this simple marker to improve mental health risk assessment and screening.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Macalli M,Côté S,Tzourio Cdoi
10.1016/j.jad.2020.02.009subject
Has Abstractpub_date
2020-04-01 00:00:00pages
512-519eissn
0165-0327issn
1573-2517pii
S0165-0327(19)32926-Xjournal_volume
266pub_type
杂志文章abstract:BACKGROUND:Telomeres are protective DNA-protein complexes forming the chromosome ends. TL differs between tissues. Shorter telomere length (TL) in blood leukocytes (LTL) has been associated with major depression, and with previous exposure to childhood adversity. TL studies on non-invasively sampled salivary DNA are le...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.09.025
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:To examine the psychotropic medication utilization and compare adherence to treatment regimens in pediatric bipolar depression patients. METHODS:2003-2007 MAX data from four geographically diverse states were used. According to the regimen received by the patients (6-18 years) in the first month after the i...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.04.034
更新日期:2013-09-05 00:00:00
abstract:BACKGROUND:Early intervention in depression has been critical to prevent its negative impact including suicide. Recent blood biomarker studies for major depressive disorder (MDD) have suggested that tryptophan-kynurenine and lipid related metabolites are involved in the pathophysiology of MDD. However, there have been ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.01.014
更新日期:2018-04-15 00:00:00
abstract:BACKGROUND:Evaluations of clinical depression are traditionally based on verbal information. Nonverbal expressive behavior, however, being associated with a person's reflexive responses, may reveal negative emotional or social processes that are not under complete control of the patients. However, investigations of non...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.05.002
更新日期:2013-09-25 00:00:00
abstract::The accumulation of histamine into blood platelets of depressed patients, lithium-treated patients and controls was determined using radio-labelled histamine. All groups had significantly different mean accumulation rates: the depressives had the lowest, the controls had the highest while the lithium-treated patients ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(84)90033-8
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND:This study compares antidepressant efficacy and tolerability of citalopram given either orally or as a slow drop infusion. METHODS:Citalopram (40 mg/day) was administered double-blindly as tablets or slow-drop infusion during the first 10 days and then open, orally, up to treatment Day 42. RESULTS:In 60 mo...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(98)00024-x
更新日期:1998-06-01 00:00:00
abstract:INTRODUCTION:Bipolar disorder (BD) often starts in childhood or adolescence. There is considerable scepticism outside the United States over the validity, stability and prevalence of BD in children and adolescents. Persistence of course lends support to the validity of a diagnosis. OBJECTIVES:To describe the longitudi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.01.013
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Cloninger's psychobiological model of personality has been extensively applied to subjects affected by mood disorders (MOOD). However, most studies are widely heterogeneous in terms of sample size, methods of assessment, and selection of participants. METHODS:We conducted a systematic review of literature a...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jad.2015.12.077
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:The aim was to examine the prevalence and consequences of co-occurring insomnia and hypersomnia symptoms in depressed adults drawn from a representative sample of the U.S. population. METHOD:Data from 687 National Comorbidity Survey Replication (NCS-R) respondents meeting criteria for a major depressive epi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.05.060
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Alexithymia is a personality construct predominately associated with an impaired ability to identify and communicate emotions. Functional imaging studies showed that an altered function of the anterior cingulate cortex (ACC) may be relevant in alexithymia. In this study we investigated if the altered functio...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.06.012
更新日期:2012-02-01 00:00:00
abstract::The authors compared the presentation and course of major depression in male geriatric inpatients with and without a diagnosis of dementia. Of 326 consecutive admissions to an inpatient geropsychiatry unit, 22 (7%) had a diagnosis of major depression without dementia, 35 (11%) had major depression with dementia. Both ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)01430-4
更新日期:1997-12-01 00:00:00
abstract::Plasma levels of nortriptyline below 50 ng/ml or above 150 ng/ml have been reported to yield results inferior to intermediate levels. In the present study, patients with uncomplicated primary, nonbipolar depression were randomly assigned to 12 weeks of treatment with NT alone or with cognitive therapy. Nine of 35 pati...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0165-0327(85)90034-5
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND:Recent studies have suggested that eating and sleep problems during early childhood may pose as risk factors for mood and anxiety disorders in later life. We aim to study the associations between early childhood sleep and eating problems, specifically high motor activity during sleep and irregularities in sl...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2006.05.025
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:China has one of the highest suicide rates in the world; however, the recent trends in suicide have not been adequately studied. This study aimed to examine the potential changes in the rates and characteristics in a Chinese population. METHODS:Data on suicide deaths in 1991-2010 were extracted from the Sha...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.09.020
更新日期:2013-04-25 00:00:00
abstract:BACKGROUND:This study examines whether (1) older maternal age is associated with increased risk of depressive episodes between four months and two years after first birth and (2) the role of subsequent reproductive, social and child factors in vulnerability to later onset depression. METHOD:592 women were recruited in...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.01.025
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Although several researches investigated Default Mode Network (DMN) alterations in individuals with anxiety disorders, up to now no studies have investigated DMN functional connectivity in non-clinical individuals with high-trait-anxiety using quantitative electroencephalography (EEG). Here, the main aim was...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.12.071
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Interpersonal sensitivity is a personality trait that describes as excessive awareness of both the behaviour and feelings of others. High interpersonal sensitivity has been associated with the development and maintenance of mental health problems. This study aimed to examine whether the Italian version of th...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.12.012
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:The goal of this study was to compare development of emotional symptomatology during smoking cessation with transdermal nicotine patches in subjects with and without a history of depression. METHODS:Twenty-five subjects, 14 with a history of depression and 11 without such a history, were evaluated before be...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00468-2
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:Recognition of depression and anxiety by general practitioners (GPs) is suboptimal and there is uncertainty as to whether particular somatic health problems hinder or facilitate GP recognition. The objective of this study was to investigate the associations between somatic health problems and GP recognition ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.08.030
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:The purpose of this paper was to evaluate relationships between sociodemographic, pregnancy, obstetric, and postnatal variables and postpartum depression, anxiety and stress levels in new mothers. METHOD:One-hundred-thirty-nine women completed the baseline questionnaire and 105 completed the follow-up quest...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.08.054
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Studies suggest that differentiating melancholic from non-melancholic depressive disorders is advanced by use of illness course as well as symptom variables but, in practice, potentially differentiating variables are generally positioned as having equal value. Judging that differentiating features are more l...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.03.057
更新日期:2015-07-15 00:00:00
abstract:BACKGROUND:After the one-child policy has been effective for over 30 years, China implemented the universal two-child policy in 2015. The number of high-risk pregnant women had increased dramatically ever since, increasing negative health outcomes for both mothers and children. Our study aims to investigate the status ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.11.148
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Several self-report rating scales have been developed to assess suicidal ideation, yet few examine other factors related to increased suicidal risk, and even fewer have been validated in both adolescents and adults. We evaluate the 14-item Concise Health Risk Tracking - Self Report (CHRT-SR), a measure previ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.03.007
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Psychostimulants have been used in the treatment of depression, with mixed results. This meta-analysis examines the efficacy and tolerability of the stimulant Lisdexamfetamine (LDX) as an add-on strategy in those with MDD who have failed to respond to an antidepressant. METHOD:Randomized control trials were...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析
doi:10.1016/j.jad.2017.09.041
更新日期:2018-01-15 00:00:00
abstract:INTRODUCTION:Research has progressively focused on antenatal psychological disease of expectant mothers, showing that anxiety and depression as well as fear of childbirth occur frequently during pregnancy. Some studies have investigated the connection between anxiety, depression, and fear of childbirth with contrasting...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.10.045
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Postpartum depression (PPD) negatively impacts maternal health, parenting and development of children. Most previous studies on PPD risk factors are based on Western populations. Additionally, little is known about the association between psychosocial factors during early pregnancy period and PPD. We aimed t...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.03.026
更新日期:2020-05-15 00:00:00
abstract:BACKGROUND:Although exposure to direct forms of childhood maltreatment is among the most widely studied risk factors for nonsuicidal self-injury (NSSI), research on NSSI has largely overlooked the role of exposure to indirect forms of child maltreatment (i.e., witnessing domestic violence). To address this gap in the l...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.04.041
更新日期:2016-08-01 00:00:00
abstract:INTRODUCTION:Psychotic symptoms in bipolar II disorder, allowed by definition only during a depressive episode, are present in a range between 3% and 45%. Little is known regarding the impact of psychotic symptoms on the clinical course of bipolar II patients. Findings from previous reports are controversial and focuse...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2010.03.028
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Recent research has shown that a polymorphism in the dopamine D2 receptor gene (DRD2) moderates the association between stressful life events and depression. The present study builds off this literature and examines whether DRD2 moderates the effect of violent victimization on depression. Furthermore, the cu...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2008.03.027
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:Because of the relationship between childhood behavior disorders and adult substance abuse, we hypothesized that substance abusing adult bipolars were more likely to have had behavior disorders as children than nonabusing bipolar adults. METHODS:Conduct disorder (CD) symptoms in 132 bipolar adults were compa...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00176-6
更新日期:1998-03-01 00:00:00