Abstract:
OBJECTIVE:The prevalence of inflammatory bowel disease [IBD, Crohn's disease (CD) and ulcerative colitis (UC)] in Puerto Rico has increased significantly in recent years. Experience with these diseases outside of a referral center is limited. A registry for IBD, created by the University of Puerto Rico (UPR) Center for IBD, has collected data from subjects all over the island for 15 years. We analyzed the medication profiles and IBD-related surgeries of the registrants in order to characterize the therapies used and to identify any trends in disease severity. METHODS:This descriptive study reports on the medication profiles of 507 individuals with IBD (1995 to 2007). Descriptive statistics related to gender, diagnosis, pharmacological therapies (aminosalicylates, steroids, immune modulators, and anti-TNF antibodies), and IBD-related surgical interventions (as indicators of disease severity) are presented. RESULTS:The study included 256 females and 251 men. There were 241 patients with UC (48%) and 266 patients with CD (52%). The great majority of them had received aminosalicylates and steroids. Biological agents and immune modulators were less commonly used, generally in IBD patients who had undergone surgical procedures. Steroid use was almost equivalent in both IBD populations despite a trend towards greater steroid use both in UC patients with colectomies and in nonsurgical CD patients. CONCLUSION:Aminosalicylates and steroids are the mainstays of medical treatment for IBD in Puerto Rico. The use of biological agents and immune modulators appears to be limited to severe disease. A prospective analysis to detect changes in prescribing practices, as a step-down approach becomes more prevalent, is needed.
journal_name
P R Health Sci Jjournal_title
Puerto Rico health sciences journalauthors
Meléndez JD,Larregui Y,Vázquez JM,Carlo VL,Torres EAsubject
Has Abstractpub_date
2011-03-01 00:00:00pages
3-8issue
1eissn
0738-0658issn
2373-6011journal_volume
30pub_type
杂志文章abstract::Alzheimer's Disease. The untold story. After considering the potential relationship between amyloid deposits and myxedematous infiltrations, the hypothesis is formulated that Alzheimer's disease may be due to functional hypothyroidism and may thus respond to thyroid therapy. ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1993-06-01 00:00:00
abstract::This article examines the available data on the health status of Puerto Rican women in the United States. Statistics on reproductive health, cancer and AIDS indicate that the health status of these women is lower than that of both their U.S. and island counterparts. Usually, the health of immigrants lies somewhere bet...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract::113 rhesus monkeys, representing 4 age classes, 3 matrilines, and immigrant adult males in a 161-member Cayo Santiago-derived troop living in a 2-acre enclosure, were sampled for levels of plasma ACTH and cortisol during a period of capture and brief cage confinement for routine veterinary examination. ACTH levels sho...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::The World Health Organization criteria for the diagnosis of Osteopenia and Osteopoposis was applied to a control group of 33 females ages 50 to 59 years and 24 females ages 60 to 69 years. The general exclusion criteria for the selection of subjects included early menopause and diseases, use of drugs and toxic habits ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVE:To determine the frequency of pediatric brain tumors treated at the University Pediatric Hospital of Puerto Rico over a 6-year period and examine the demographic data and tumor histology of patients in different age groups. METHODS:A retrospective study was undertaken at the University Pediatric Hospital. We...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::Diagnosing cancer using microarray analysis to study differential gene expression has been a recent focus of intense research Although several very sophisticated analysis tools have been developed with this aim in mind, it still remains a challenge to keep these methods free of parametric adjustments as well as mainta...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract::This is a case report of a patient who developed a nodule in one foot, which upon biopsy, was diagnosed as tungiasis, a cutaneous infestation caused by a human flea. The natural life cycle, clinical and pathological expressions are discussed. ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVE:To compare the variations in central corneal thickness and intraocular pressure measurements according to race, gender, and age. METHODS:A non-concurrent prospective study of 372 (744 eyes) glaucoma patients was conducted. Central corneal thickness was measured with ultrasound pachymeter and intraocular pres...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:A preliminary investigation to test the efficacy of intravenous propranolol in reducing the cesarean section rate in nulliparas in active labor and evaluate its effect on neonatal and maternal outcomes. METHODS:Fifty seven nulliparous patients admitted in active labor were randomly divided into two groups: a...
journal_title:Puerto Rico health sciences journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:Dental caries is one of the most prevalent chronic diseases in children. Currently, no data are available on dental caries prevalence in the Dominican Republic. The purpose of this study was to estimate the prevalence of dental caries in schoolattending 12-year-olds in San Pedro de Macorís, Dominican Republic...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:This study intends to determine the prevalence of multidrug resistant (MDR) infections by A. baumannii, K. pneumoniae and P. aeruginosa in a tertiary care teaching hospital intensive care unit (ICU) in San Juan, PR, estimate the mortality rate and compare the morbidity and mortality differences among those tr...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2019-03-01 00:00:00
abstract::1. To know if the absence of desensitization in the chicken is characteristic of avian tissues, we studied the anaphylactic reaction in the duck. The contractions elicited in pieces of small intestine of actively immunized ducks upon exposure to the specific antigen, or Schultz-Dale reaction, were compared to similar ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract:OBJECTIVE:Skin biomechanics are physical properties that protect the body from injury. Little is known about differences in skin biomechanics in racial/ethnic groups and the role of skin color in these differences. The purpose of this study was to determine the relationship between skin biomechanics (viscoelasticity, h...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Most studies about abuse, mistreatment and neglect of the aged have relied upon definitions provided by professionals and not the aged themselves whereas studies point out that definitions given by the aged do not correspond with those of professionals. Limited attention has been given to this topic in Puert...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:This study aimed to assess the demographic, behavioral, and clinical factors associated with HIV and syphilis infection among a sample of men attending a sexually transmitted infection clinic during 2009 to 2010 in San Juan, Puerto Rico (PR). METHODS:A sample of 350 clinical records from men visiting the cli...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:To compare the effectiveness of intravenous immunoglobulin (IVIG) alone, high dose methylprednisolone (HDMP) alone and the combination of IVIG and HDMP in the treatment of childhood immune thrombocytopenic purpura (ITP). BACKGROUND:Acute ITP in children is a self-limited disease with a benign course and low ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::This study aims to determine the prevalence of Mycobacterium tuberculosis infection and its association with HIV and other health risk factors among drug users. A sample of 716 IDUs and crack users were enrolled from community sites. Consenting subjects were tested for HIV serum antibody status. Drug users with an unk...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVE:Burnout exerts a significant negative influence on job performance, especially in such difficult jobs as those to be found in the health care industry. This research aimed to evaluate the association between 3 dimensions of burnout and demographic factors among the medical staff working in all of the hospital...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2015-12-01 00:00:00
abstract::Four hundred and sixty six non-institutionalized seniors, 65 years of age and over comprise the sample. The questions pertaining to the specific topic are made up of 17 items: 9 related to background information and 8 relating to nutritional practices. It is part of a larger study of the socio-demographic characterist...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::As part of the January, 1988 trapping of the Cayo Santiago rhesus colony a number of morphometric measurements and serum were collected to examine metabolic and hormonal changes associated with spontaneous obesity. Measurements included body weights, crown-rump lengths, abdominal and scapular skinfolds and circumferen...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::A retrospective review was performed from November 2011 through June 2012 in 49 stable patients receiving ambulatory hemodialysis at the dialysis unit of the University Hospital in San Juan. Measurements of serum phosphate, serum calcium (corrected to albumin levels), intact parathyroid hormone (PTH), and pulse pressu...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:This study aimed to assess the role of gender on HIV/AIDS stigma among 507 medical students in Puerto Rico. METHODS:A secondary data analysis was performed with baseline measurements of a controlled randomized study. RESULTS:Unadjusted analyses showed that the overall multivariate test for gender was signif...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2012-12-01 00:00:00
abstract::Primary hepatic actinomycosis is an uncommon entity. We report the case of a young man with past history of an appendectomy who presented with fever, weight loss and a liver mass that was initially suspected to be neoplastic. Percutaneous liver biopsy revealed actinomyces-like organisms. The patient was treated with i...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:1992-04-01 00:00:00
abstract::Cayo Santiago has provided the opportunity to study primate biology in a free-ranging neutral environment free of provocative human influences. Rarely, if ever, does such a situation occur in natural rhesus habitats in Asia. This Cayo Santiago advantage has permitted fine-scale analyses of the details of behavior, eco...
journal_title:Puerto Rico health sciences journal
pub_type: 历史文章,杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::The present study analyzed the socioeconomic determinants of health insurance status among Puerto Ricans. Given the fact that there are no mandated health benefits for private firms in Puerto Rico and that health services are provided almost free of charge in government facilities, Puerto Rico provides a unique case s...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1988-04-01 00:00:00
abstract::Genital human papillomavirus (HPV) infection is one of the most commonly diagnosed sexually transmitted infections world-wide. Over the last two decades, research has established a strong causal link between specific types of HPV infection and cancer, particularly cervical, anal, vulvar/vaginal, penile, and oropharyng...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2010-09-01 00:00:00
abstract::Breastfeeding mothers need orientation and help in order to succeed with breastfeeding. Lack of support from health professionals and societal barriers result in a median duration of breastfeeding in Puerto Rico of only 3 weeks. A telephone warm line at our breastfeeding clinic tries to provide some much-needed suppor...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract::We tested a dietary supplement formulated with a synergistic combination of vitamins, minerals, herbals in a group of 15 patients with uncontrolled diabetes type II. The supplement was given for 30 days. Fasting blood glucose was measured prior to the supplementation and at the end of the 30 days treatment period. Blo...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2004-06-01 00:00:00
abstract::Since the year 2000, extracorporeal membrane oxygenation (ECMO) support for cardiac failure has been employed in the post operative care of children at the Centro Cardiovascular de Puerto Rico y el Caribe. Our experience with the application of ECMO had been limited to circulatory support after repair of congenital ca...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:The recent FDA approval of non-prescription sales of Plan B, an emergency contraceptive method to those 18 years old and over, gives a prominent role to pharmacists in providing timely access to emergency contraception (EC). While this decision affects Puerto Rico, no studies on non-prescription EC in Puerto...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2007-09-01 00:00:00