Abstract:
CONTEXT:Early intensive behavioral and developmental interventions for young children with autism spectrum disorders (ASDs) may enhance developmental outcomes. OBJECTIVE:To systematically review evidence regarding such interventions for children aged 12 and younger with ASDs. METHODS:We searched Medline, PsycINFO, and ERIC (Education Resources Information Center) from 2000 to May 2010. Two reviewers independently assessed studies against predetermined inclusion/exclusion criteria. Two reviewers independently extracted data regarding participant and intervention characteristics, assessment techniques, and outcomes and assigned overall quality and strength-of-evidence ratings using predetermined criteria. RESULTS:Thirty-four unique studies met inclusion criteria. Seventeen studies were case series; 2 were randomized controlled trials. We rated 1 study as good quality, 10 as fair quality, and 23 as poor quality. The strength of the evidence overall ranged from insufficient to low. Studies of University of California Los Angeles/Lovaas-based interventions and variants reported clinically significant gains in language and cognitive skills in some children, as did 1 randomized controlled trial of an early intensive developmental intervention approach (the Early Start Denver Model). Specific parent-training approaches yielded gains in short-term language function and some challenging behaviors. Data suggest that subgroups of children displayed more prominent gains across studies, but participant characteristics associated with greater gains are not well understood. CONCLUSIONS:Studies of Lovaas-based approaches and early intensive behavioral intervention variants and the Early Start Denver Model resulted in some improvements in cognitive performance, language skills, and adaptive behavior skills in some young children with ASDs, although the literature is limited by methodologic concerns.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Warren Z,McPheeters ML,Sathe N,Foss-Feig JH,Glasser A,Veenstra-Vanderweele Jdoi
10.1542/peds.2011-0426subject
Has Abstractpub_date
2011-05-01 00:00:00pages
e1303-11issue
5eissn
0031-4005issn
1098-4275pii
peds.2011-0426journal_volume
127pub_type
杂志文章,评审相关文献
PEDIATRICS文献大全abstract::Ultrasound was used to evaluate 100 pediatric patients suspected of having a mass. This technique was found to be useful in several ways: (1) differentiation of cystic, solid, and complex masses, which is not usually possible with routine roentgenographic evaluation; (2) delineation of free fluid collections from thos...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
abstract::A retrospective record review was used to examine utilization of a pediatric walk-in clinic available to an entire urban community and to evaluate the effectiveness of follow-up care for a sample of the users of this facility who receive their regular pediatric care at a local comprehensive child health center. Result...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to examine the relationship between duration of poverty and the health of preschool children in the Quebec Longitudinal Study of Child Development birth cohort. METHODS:Data from the Quebec Longitudinal Study of Child Development for 1950 children who were followed annually u...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1750
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE:High rates of use of child safety seats have been achieved. A remaining challenge in child passenger safety is to reach the Healthy People 2010 objective of child safety seat use to 100%. Several factors have been reported to influence child safety seat use. A child safety seat Hassles Scale was developed to ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-2211
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:The goal was to examine the effectiveness of an early intervention on cognitive and motor outcomes at corrected ages of 3 and 5 years for children with birth weights (BWs) of <2000 g. METHODS:A randomized controlled trial of a modified version of the Mother-Infant Transaction Program was performed. Outcomes ...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2010-0778
更新日期:2010-11-01 00:00:00
abstract::Since 1961 the Committee on Nutrition of the American Academy of Pediatrics has recommended that prophylactic vitamin K be administered parenterally to all newborn infants, although the exact requirement for vitamin K in the newborn infant is unknown. There is little information about the vitamin K1 (phylloquinone, pr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:The Patient Protection and Affordable Care Act (ACA) has the potential to reduce the number of uninsured children in the United States by as much as 40%. The extent to which immigrant families are aware of and interested in obtaining insurance for their children is unclear. METHODS:Data from the 2011-2012 N...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-3337
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to determine whether multisystemic therapy (MST), an intensive, home-based psychotherapy, could decrease diabetes-related stress among adolescents with chronically poorly controlled type 1 diabetes. Stress was also evaluated as a mediator of the effect of MST on adherence and metabo...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2005-0638
更新日期:2005-12-01 00:00:00
abstract:OBJECTIVE:Connatal pneumonia caused by group B streptococcal (GBS) infection may be associated with surfactant dysfunction. We investigated the effects of surfactant treatment in term and preterm neonates with GBS infection and respiratory failure, in comparison with corresponding data from a control population of noni...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1542/peds.106.5.957
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:The purpose of this work was to investigate whether using a muscle relaxant would improve intubation conditions in infants, thereby decreasing the incidence and duration of hypoxia and time and number of attempts needed to successfully complete the intubation procedure. PATIENTS/METHODS:This was a prospectiv...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2006-0590
更新日期:2006-10-01 00:00:00
abstract::Despite substantial progress, adolescents remain at high risk for human immunodeficiency virus (HIV) infection. Two independent random digit dial statewide Massachusetts surveys of 16- to 19-year-old persons conducted August through September 1986 and 1988 revealed that the proportion of teenagers who had discussed ac...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:To compare multiple logistic regression and neural network models in predicting death for extremely low birth weight neonates at 5 time points with cumulative data sets, as follows: scenario A, limited prenatal data; scenario B, scenario A plus additional prenatal data; scenario C, scenario B plus data from t...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-2099
更新日期:2005-12-01 00:00:00
abstract::The transcripts of tape-recorded interviews of pediatric endocrinologists and patients with Turner's syndrome and their parents were reviewed in consultation with child psychoanalysts in order to evaluate certain aspects of communication between patients and doctors. The transcripts showed that the doctors often talke...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract:OBJECTIVE:Findings from published studies suggest that the postoperative recovery process is more painful, slower, and more complicated in adult patients who had high levels of preoperative anxiety. To date, no similar investigation has ever been conducted in young children. METHODS:We recruited 241 children aged 5 to...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-2920
更新日期:2006-08-01 00:00:00
abstract::An overview and update are offered on difficulties experienced by children with monaural sensorineural deafness. It is the general consensus that children with unilateral hearing loss experience few, if any, communication and/or educational problems. The medical and educational status of a group (N = 60) of children w...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1984-08-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to identify risk factors for developing chronic idiopathic thrombocytopenic purpura in a cohort of pediatric patients with idiopathic thrombocytopenic purpura. METHODS:We conducted a retrospective cohort analysis of 259 children who were diagnosed with idiopathic thrombocytope...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-1129
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:Although vision screening for preschool children is recommended for detecting amblyopia, many pediatric and family medicine practices do not screen preschool-aged children. The aim of this study was to determine the effect of a training program for primary care clinical staff on vision screening behavior and ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.112.1.e17
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:This technical report reviews and synthesizes the published literature on racial/ethnic disparities in children's health and health care. METHODS:A systematic review of the literature was conducted for articles published between 1950 and March 2007. Inclusion criteria were peer-reviewed, original research ar...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2010-0188
更新日期:2010-04-01 00:00:00
abstract::To assess the relative competence of pediatricians and general practitioners in managing febrile illnesses in childhood, a prospective study was undertaken of 259 children less than 10 years of age seen consecutively at the emergency room of a children's hospital and a general hospital. Both groups of patients were si...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1982-10-01 00:00:00
abstract:OBJECTIVE:Adolescence is an important period of risk for the development of lifelong smoking behaviors. Compelling, although inconsistent, evidence suggests a relationship between parental smoking and the risk of smoking initiation during adolescence. This study investigates unresolved issues concerning the strength an...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-2251
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:To develop and test an evidence-based model for reducing medication errors and harm in hospitalized children. METHODS:Prospective interrupted time series study evaluating the effectiveness of a multifaceted, staged intervention over 4 years in a major urban pediatric referral hospital. Guidelines for safe p...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-1902
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:To our knowledge, the risk of renal scarring in children with a urinary tract infection (UTI) has not been systematically studied. OBJECTIVE:To review the prevalence of acute and chronic renal imaging abnormalities in children after an initial UTI. METHODS:We searched Medline and Embase for English-, Frenc...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2010-0685
更新日期:2010-12-01 00:00:00
abstract::This article, written by a parent of 2 youths with special health care needs and a pediatrician, builds on the Medical Home framework to give concrete examples of what physicians and families can and should do to prepare families for transition(s). The article consists of 3 parts. The first part is an introduction giv...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.113.3.e159
更新日期:2004-03-01 00:00:00
abstract::A newborn with graft-vs-host (GVH) disease following an exchange transfusion was treated by attempting to eradicate the incompatible graft and to reconstitute the child hematologically and immunologically with a bone marrow transplant. The patient was a female term infant (blood group B, Rh+ Coombs test positive) who ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1982-07-01 00:00:00
abstract:OBJECTIVE:Abnormalities in cognitive function and brain structure have been reported in acutely ill adolescents with anorexia nervosa, but whether these abnormalities persist or are reversible in the context of weight restoration remains unclear. Brain structure and cognitive function in female subjects with adolescent...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-0170
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:We investigated the effects of self-regulation of slow cortical potentials for children with attention-deficit/hyperactivity disorder. Slow cortical potentials are slow event-related direct-current shifts of the electroencephalogram. Slow cortical potential shifts in the electrical negative direction reflect ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-2478
更新日期:2006-11-01 00:00:00
abstract::A study was done to assess the necessity of hospital care for poisoning episodes in children less than 5 years old and to evaluate the impact of a regional poison center on the use of emergency rooms for pediatric poisonings. Of the pediatric patients seen in emergency rooms for acute poisonings, 63% did not require t...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00
abstract::The hypothesis that the parents and siblings of children with nephrotic syndrome are more likely to develop psychosocial problems than those of healthy children was tested. Seventy-nine siblings from 36 such families were compared with 79 healthy children from closely matched families using interviews, parent rating s...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVE:To determine the frequency of selective nontreatment of extremely premature, critically ill, or malformed infants among all infant deaths in a level III intensive care nursery (ICN) and to determine the reasons documented by neonatologists for their decisions to withdraw or withhold life support. METHODS:Thi...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.99.1.64
更新日期:1997-01-01 00:00:00
abstract::Young patients and their parents often are unsure about what represents normal menstrual patterns, and clinicians also may be unsure about normal ranges for menstrual cycle length and amount and duration of flow through adolescence. It is important to be able to educate young patients and their parents regarding what ...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2006-2481
更新日期:2006-11-01 00:00:00