[An in-vivo evaluation of Brilliant Blue G in macular surgery].

Abstract:

OBJECTIVE:The aim of this study was to evaluate the functional outcome of Brilliant Blue G (BBG) and the staining properties in macular surgery. METHODS:BBG was applied during vitrectomy for macular holes (n = 21) or epiretinal membranes (n = 18) in a prospective, non-comparative consecutive series of patients (Brilliant Peel®; Fluoron® GmbH, Neu-Ulm, Germany). Before and after surgery all patients underwent a complete clinical examination including measurement of best corrected visual acuity and intraocular pressure, perimetry, fundus photography and optical coherence tomography. RESULTS:Vitrectomy was performed in combination with a cataract operation in 14 patients. All macular holes were closed successfully. Visual acuity was in average 0.16 preoperatively in macular hole cases and increased up to 0.4 after 6 months. Visual acuity of patients with epiretinal membranes changed on average from 0.3 to 0.45 after 6 months. The retina thickness in patients with epiretinal membranes was initially 402.6 µm according to the OCT and 304.7 µm after 6 months postoperatively. No toxic effects attributable to the dye were noted during patient follow-up, especially all perimetry tests were normal. CONCLUSIONS:Brilliant blue provides a sufficient and selective staining of the ILM. No retinal toxicity or adverse effects related to the dye were observed in this study. The long-term safety of this dye will have to be evaluated in larger patient series and a longer follow-up.

journal_name

Klin Monbl Augenheilkd

authors

Höing A,Remy M,Dirisamer M,Priglinger S,Schönfeld CL,Kampik A,Haritoglou C

doi

10.1055/s-0031-1273351

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

724-8

issue

8

eissn

0023-2165

issn

1439-3999

journal_volume

228

pub_type

杂志文章
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    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:

    authors: Reiner J

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  • [Enhancements after Refractive Corneal Surgery].

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    authors: Huismans H

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    doi:

    authors: Schulze DP,Freese R,Sauerwald R

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  • [Functional Results One Year after Implantation of a Bitoric, Trifocal Intraocular Lens].

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  • [Unusual presentation of retinoblastoma].

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  • [Intravitreal Therapy Combining Dexamethasone and Bevacizumab in Treating Radiation Retinopathy and Opticopathy].

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    authors: Lisch K

    更新日期:1976-07-01 00:00:00

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    abstract::Prophylactic cryo coagulation is especially suitable when there is cloudy media, e.g. blood in the vitreous body or a cataract which would prevent light or laser coagulation. Cryo lesions applied under ophthalmoscopic control are without complication. The paper reviews the 116 eyes collected in 1971 and augments it wi...

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    doi:

    authors: Kreissig I,Ruge I

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    doi:10.1055/s-2008-1057252

    authors: Härting F,Mellin KB

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  • [Recurrent fibrous histiocytoma at the corneoscleral limbus].

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    authors: Mewe L,Promesberger HW

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    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Jaeger W

    更新日期:1989-12-01 00:00:00

  • [Sensitivity of the computer perimeter Competer in early glaucomatous loss of visual field. A controlled study].

    abstract::Comparative examinations were carried out under controlled conditions in 101 eyes of 66 open-angle glaucoma patients with field defects (Stages I-III according to Aulhorn) with the Octopus and Competer computerized perimeters. The results of the Octopus perimetry were selected as a reference system to evaluate the sen...

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    authors: Gramer E,Gerlach R,Krieglstein GK

    更新日期:1982-03-01 00:00:00

  • [Clinical applications of molecular diagnosis of retinoblastoma ain 15 families].

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    pub_type: 杂志文章

    doi:

    authors: Fuchs J

    更新日期:1977-12-01 00:00:00

  • [Long-term follow-up after surgery for exodeviation].

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    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:

    authors: Huismans H

    更新日期:1977-05-01 00:00:00

  • [Anthocyanosides in the treatment of retinopathies (author's transl)].

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    更新日期:1981-05-01 00:00:00

  • [Are prism glasses a sensible measure in treatment of dyslexia?].

    abstract::A short summary of the characteristics of speaking, reading and writing is given, followed by the respective anatomical, physiological and neuropsychological counterparts, which are to be described as the "Hör-Denk-Sprech-Seh-Schreib-Organismus" (H-D-S-S-SCH-O). Various disorders occurring in the H-D-S-S-SCH-O as well...

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    authors: Schwarz C

    更新日期:1992-05-01 00:00:00

  • [Value of indocyanine green angiography in localization of occult choroid neovascularization].

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    更新日期:1996-05-01 00:00:00

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  • [Correlation between prognostically predicted and actually attained refraction].

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    pub_type: 杂志文章

    doi:

    authors: Prammer G

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