The role of bacterial biofilm in persistent infections and control strategies.

abstract：:Dental caries are the most prevalent chronic infections in the oral cavity, and Streptococcus mutans acts as the main cariogenic bacterial species. Antibacterial quaternary ammonium compounds (QAs) have been developed to preveFnt or treat dental caries. However, there is no report on the tolerance of S. mutans to QAs....

journal_title：International journal of oral science

authors： Jiang YL,Qiu W,Zhou XD,Li H,Lu JZ,Xu HH,Peng X,Li MY,Feng MY,Cheng L,Ren B

更新日期：2017-12-01 00:00:00

abstract：:By removing a part of the structure, the tooth preparation provides restorative space, bonding surface, and finish line for various restorations on abutment. Preparation technique plays critical role in achieving the optimal result of tooth preparation. With successful application of microscope in endodontics for >30 ...

journal_title：International journal of oral science

authors： Yu H,Zhao Y,Li J,Luo T,Gao J,Liu H,Liu W,Liu F,Zhao K,Liu F,Ma C,Setz JM,Liang S,Fan L,Gao S,Zhu Z,Shen J,Wang J,Zhu Z,Zhou X

更新日期：2019-10-02 00:00:00

abstract：:Although a few studies have shown that vascularity is increased from normal mucosa to dysplasia to carcinoma suggesting that disease progression in the oral mucosa is accompanied by angiogenesis. The role in lymph node metastasis in oral squamous cell carcinoma (OSCC) is equivocal. Role of angiogenesis in OSCC develop...

journal_title：International journal of oral science

authors： Shivamallappa SM,Venkatraman NT,Shreedhar B,Mohanty L,Shenoy S

更新日期：2011-10-01 00:00:00

abstract：:Both bone morphogenetic protein 2 (BMP2) and the wingless-type MMTV integration site (WNT)/β-catenin signalling pathway play important roles in odontoblast differentiation and dentinogenesis. Cross-talk between BMP2 and WNT/β-catenin in osteoblast differentiation and bone formation has been identified. However, the ro...

journal_title：International journal of oral science

authors： Yang J,Ye L,Hui TQ,Yang DM,Huang DM,Zhou XD,Mao JJ,Wang CL

更新日期：2015-06-26 00:00:00

abstract：:The presence of a large palatal or maxillary defect after partial or total maxillectomy for tumor, trauma or congenital deformation poses a challenge to prosthodontists, particularly when the use of an implant cannot be considered. This case report described the use of an air valve in a hollow silicone obturator to ma...

journal_title：International journal of oral science

authors： Hou YZ,Huang Z,Ye HQ,Zhou YS

更新日期：2012-06-01 00:00:00

abstract：:For a long time, oral disease is one of the major problems of the public health for its high prevalence and incidence throughout the world, which is especially true for low-income populations. Since China's economic reform in 1978, great changes have taken place in China. These changes have significant impact on and h...

journal_title：International journal of oral science

authors： Hu DY,Hong X,Li X

更新日期：2011-01-01 00:00:00

abstract：:Tissue engineering allows the design of functionally active cells within supportive bio-scaffolds to promote the development of new tissues such as cartilage and bone for the restoration of pathologically altered tissues. However, all bone tissue engineering applications are limited by a shortage of stem cells. The ad...

journal_title：International journal of oral science

authors： Xiao Y,Mareddy S,Crawford R

更新日期：2010-09-01 00:00:00

abstract：:Saliva is secreted from the salivary glands and has multiple functions, including mouth cleaning and protection, antibacterial effects and digestion. With the rapid advancement in salivaomics, saliva is well recognized as a pool of biological markers. Saliva, as a non-invasive and safe source, could be a substitute fo...

journal_title：International journal of oral science

authors： Zhang CZ,Cheng XQ,Li JY,Zhang P,Yi P,Xu X,Zhou XD

更新日期：2016-09-29 00:00:00

abstract：:The oral microbial community is widely regarded as a latent reservoir of antibiotic resistance genes. This study assessed the molecular epidemiology, susceptibility profile, and resistance mechanisms of 35 methicillin-resistant Staphylococcus epidermidis (MRSE) strains isolated from the dental plaque of a healthy huma...

journal_title：International journal of oral science

authors： Tang B,Gong T,Cui Y,Wang L,He C,Lu M,Chen J,Jing M,Zhang A,Li Y

更新日期：2020-05-09 00:00:00

abstract：:Osteoporosis is a serious public bone metabolic disease. However, the mechanisms underlying bone loss combined with ageing, which is known as senile osteoporosis, remains unknown. Here we show the detailed phenotype of this disease caused by SIRT6 knock out (KO) in mice. To the best of our knowledge, this is the first...

journal_title：International journal of oral science

authors： Zhang DM,Cui DX,Xu RS,Zhou YC,Zheng LW,Liu P,Zhou XD

更新日期：2016-06-30 00:00:00

abstract：:The human microbiome functions as an intricate and coordinated microbial network, residing throughout the mucosal surfaces of the skin, oral cavity, gastrointestinal tract, respiratory tract, and reproductive system. The oral microbiome encompasses a highly diverse microbiota, consisting of over 700 microorganisms, in...

journal_title：International journal of oral science

authors： Xiao J,Fiscella KA,Gill SR

更新日期：2020-04-30 00:00:00

abstract：:Along with the development of new materials, advanced medical imaging and surgical techniques, osseointegrated dental implants are considered a successful and constantly evolving treatment modality for the replacement of missing teeth in patients with complete or partial edentulism. The importance of restoring the per...

journal_title：International journal of oral science

authors： Huang Y,Bornstein MM,Lambrichts I,Yu HY,Politis C,Jacobs R

更新日期：2017-03-01 00:00:00

abstract：:Secondary caries due to biofilm acids is a primary cause of dental composite restoration failure. To date, there have been no reports of dental composites that can repel protein adsorption and inhibit bacteria attachment. The objectives of this study were to develop a protein-repellent dental composite by incorporatin...

journal_title：International journal of oral science

authors： Zhang N,Chen C,Melo MA,Bai YX,Cheng L,Xu HH

更新日期：2015-06-26 00:00:00

abstract：:This study aimed to compare epithelial cells derived from human embryonic stem cells (hESCs) to human ameloblast-lineage cells (ALCs), as a way to determine their potential use as a cell source for ameloblast regeneration. Induced by various concentrations of bone morphogenetic protein 4 (BMP4), retinoic acid (RA) and...

journal_title：International journal of oral science

authors： Zheng LW,Linthicum L,DenBesten PK,Zhang Y

更新日期：2013-03-01 00:00:00

abstract：:Apoptosis or programmed cell death plays an essential role in chemotherapy-induced tumor cell killing, and inducers of apoptosis are commonly used in cancer therapy. Treatment with Zelkova serrata extracts was performed in human gingival fibroblast (HGF), mouth epidermoid carcinoma cell (KB), lower gingival squamous c...

journal_title：International journal of oral science

authors： Kang HJ,Jang YJ

更新日期：2012-06-01 00:00:00

abstract：:A previous study demonstrated that alexidine has greater affinity for the major virulence factors of bacteria than chlorhexidine. The aim of this study was to compare the antimicrobial activity of 1% alexidine with that of 2% chlorhexidine using Enterococcus faecalis-infected dentin blocks. Sixty bovine dentin blocks ...

journal_title：International journal of oral science

authors： Kim HS,Woo Chang S,Baek SH,Han SH,Lee Y,Zhu Q,Kum KY

更新日期：2013-03-01 00:00:00

abstract：:In this study, we evaluate the influence of post surface pre-treatments on the bond strength of four different cements to glass fiber posts. Eighty extracted human maxillary central incisors and canines were endodontically treated and standardized post spaces were prepared. Four post pre-treatments were tested: (i) no...

journal_title：International journal of oral science

authors： Liu C,Liu H,Qian YT,Zhu S,Zhao SQ

更新日期：2014-03-01 00:00:00

abstract：:Retention wires permanently bonded to the anterior teeth are used after orthodontic treatment to prevent the teeth from relapsing to pre-treatment positions. A disadvantage of bonded retainers is biofilm accumulation on the wires, which produces a higher incidence of gingival recession, increased pocket depth and blee...

journal_title：International journal of oral science

authors： Jongsma MA,van der Mei HC,Atema-Smit J,Busscher HJ,Ren Y

更新日期：2015-03-23 00:00:00

abstract：:Tooth development is a complex process that involves precise and time-dependent orchestration of multiple genetic, molecular, and cellular interactions. Ameloblastin (AMBN, also named "amelin" or "sheathlin") is the second most abundant enamel matrix protein known to have a key role in amelogenesis. Amelogenesis imper...

journal_title：International journal of oral science

authors： Lu T,Li M,Xu X,Xiong J,Huang C,Zhang X,Hu A,Peng L,Cai D,Zhang L,Wu B,Xiong F

更新日期：2018-09-03 00:00:00

abstract：:After teeth are replanted, there are two possible healing responses: periodontal ligament healing or ankylosis with subsequent replacement resorption. The purpose of this study was to compare the fatigue resistance of vertically fractured teeth after bonding the fragments under conditions simulating both healing modes...

journal_title：International journal of oral science

authors： Zhu YN,Yang WD,Abbott PV,Martin N,Wei WJ,Li JJ,Chen Z,Wang WM

更新日期：2015-06-26 00:00:00

abstract：:Bone remodelling keeps going through the lifespan of human by bone formation and bone resorption. In the craniofacial region, mandibles act as the main force for biting and chewing, and also become susceptible to a common bone-loss disease, namely, apical periodontitis, once infected dental pulp is not treated timely,...

journal_title：International journal of oral science

authors： Xu R,Guo D,Zhou X,Sun J,Zhou Y,Fan Y,Zhou X,Wan M,Du W,Zheng L

更新日期：2019-08-26 00:00:00

abstract：:The root is crucial for the physiological function of the tooth, and a healthy root allows an artificial crown to function as required clinically. Tooth crown development has been studied intensively during the last few decades, but root development remains not well understood. Here we review the root development proc...

journal_title：International journal of oral science

authors： Huang XF,Chai Y

更新日期：2012-12-01 00:00:00

abstract：:Biofilms at the tooth-restoration bonded interface can produce acids and cause recurrent caries. Recurrent caries is a primary reason for restoration failures. The objectives of this study were to synthesize a novel bioactive dental bonding agent containing dimethylaminohexadecyl methacrylate (DMAHDM) and 2-methacrylo...

journal_title：International journal of oral science

authors： Zhang N,Zhang K,Weir MD,Xu DJ,Reynolds MA,Bai Y,Xu HHK

更新日期：2018-06-21 00:00:00

abstract：:To modify two-step experimental etch-and-rinse dentin adhesive with different concentrations of riboflavin and to study its effect on the bond strength, degree of conversion, along with resin infiltration within the demineralized dentin substrate, an experimental adhesive-system was modified with different concentrati...

journal_title：International journal of oral science

authors： Daood U,Swee Heng C,Neo Chiew Lian J,Fawzy AS

更新日期：2015-06-26 00:00:00

abstract：:Formation of the periodontium begins following onset of tooth-root formation in a coordinated manner after birth. Dental follicle progenitor cells are thought to form the cementum, alveolar bone and Sharpey's fibers of the periodontal ligament (PDL). However, little is known about the regulatory morphogens that contro...

journal_title：International journal of oral science

authors： Rakian A,Yang WC,Gluhak-Heinrich J,Cui Y,Harris MA,Villarreal D,Feng JQ,Macdougall M,Harris SE

更新日期：2013-06-01 00:00:00

abstract：:Bone defects caused by trauma, tumour resection, infection and congenital deformities, together with articular cartilage defects and cartilage-subchondral bone complex defects caused by trauma and degenerative diseases, remain great challenges for clinicians. Novel strategies utilising cell sheet technology to enhance...

journal_title：International journal of oral science

authors： Lu Y,Zhang W,Wang J,Yang G,Yin S,Tang T,Yu C,Jiang X

更新日期：2019-05-21 00:00:00

abstract：:Tooth decay is prevalent, and secondary caries causes restoration failures, both of which are related to demineralization. There is an urgent need to develop new therapeutic materials with remineralization functions. This article represents the first review on the cutting edge research of poly(amido amine) (PAMAM) in ...

journal_title：International journal of oral science

authors： Liang K,Wang S,Tao S,Xiao S,Zhou H,Wang P,Cheng L,Zhou X,Weir MD,Oates TW,Li J,Xu HHK

更新日期：2019-05-09 00:00:00

abstract：:Effective control of oral biofilm infectious diseases represents a major global challenge. Microorganisms in biofilms exhibit increased drug tolerance compared with planktonic cells. The present review covers innovative antimicrobial strategies for controlling oral biofilm-related infections published predominantly ov...

journal_title：International journal of oral science

authors： Jiao Y,Tay FR,Niu LN,Chen JH

更新日期：2019-10-01 00:00:00

abstract：:Drug-induced gingival overgrowth (DIGO) is recognized as a side effect of nifedipine (NIF); however, the underlying molecular mechanisms remain unknown. In this study, we found that overexpressed miR-4651 inhibits cell proliferation and induces G0/G1-phase arrest in gingival mesenchymal stem cells (GMSCs) with or with...

journal_title：International journal of oral science

authors： Han X,Yang R,Yang H,Cao Y,Han N,Zhang C,Shi R,Zhang Z,Fan Z

更新日期：2020-03-31 00:00:00

abstract：AIM:To investigate the effect of DAPT (gamma-secretase inhibitor) on the growth of human tongue carcinoma cells and to determine the molecular mechanism to enable the potential application of DAPT to the treatment of tongue carcinoma. METHODOLOGY:Human tongue carcinoma Tca8113 cells were cultured with DAPT. Cell growt...

journal_title：International journal of oral science

authors： Grottkau BE,Chen XR,Friedrich CC,Yang XM,Jing W,Wu Y,Cai XX,Liu YR,Huang YD,Lin YF

更新日期：2009-06-01 00:00:00