Diabetes Technology Use in Adults with Type 1 and Type 2 Diabetes.

abstract：:Based on the 2010 version, the 2017 World Health Organization (WHO 2017) classification is for pancreatic neuroendocrine neoplasms (PanNEN). The WHO 2017 classification introduces the novel well-differentiated neuroendocrine tumor of high grade (NET G3). A sharp distinction between NET and poorly differentiated neuroe...

journal_title：Endocrinology and metabolism clinics of North America

authors： Inzani F,Petrone G,Rindi G

更新日期：2018-09-01 00:00:00

abstract：:An approach to the diagnosis and follow-up of patients with osteoporosis is described. A system of classification of vertebral fractures is outlined, and the relative merits of different techniques for bone mineral density are discussed. The importance of identifying factors that accelerate bone loss is stressed. The ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Eastell R,Riggs BL

更新日期：1988-09-01 00:00:00

abstract：:Establishing the cause of Cushing's syndrome (CS) is one of the most challenging processes in clinical endocrinology. Biochemical testing, including measurement of plasma adrenocorticotropin (ACTH), high-dose dexamethasone suppression, and corticotropin-releasing hormone stimulation testing, is integral to the differe...

journal_title：Endocrinology and metabolism clinics of North America

authors： Lindsay JR,Nieman LK

更新日期：2005-06-01 00:00:00

abstract：:The autoimmune polyendocrinopathy syndromes are variable in presentation and can be challenging to diagnose and manage. Diagnosis of the type 1 autoimmune polyendocrinopathy syndrome can be difficult at an early age when often only one manifestation is present, and it may take years for others to appear. Increased awa...

journal_title：Endocrinology and metabolism clinics of North America

authors： Owen CJ,Cheetham TD

更新日期：2009-06-01 00:00:00

abstract：:Male infertility is a common problem but only about one quarter of patients have specific or defined conditions that make them either sterile or severely infertile. About half of these patients have untreatable primary seminiferous tubule failure, and donor insemination or adoption are the only possibilities of having...

journal_title：Endocrinology and metabolism clinics of North America

authors： Baker HW

更新日期：1994-12-01 00:00:00

abstract：:CVD is the primary cause of morbidity and mortality in patients who have diabetes mellitus. Most such patients have at least one lipid abnormality. Managing these complex lipid disorders is a crucial component of comprehensive diabetes mellitus care and limits the risk for cardiovascular morbidity and mortality. With ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Kendall DM

更新日期：2005-03-01 00:00:00

abstract：:This review provides an overview of the safety of growth hormone replacement therapy in individuals previously treated for cancer. The review focuses on the risk of disease recurrence and second neoplasm occurrence with special attention to data on childhood cancer survivors. ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Chemaitilly W,Robison LL

更新日期：2012-12-01 00:00:00

abstract：:Acromegaly is an unusual insidious but potentially serious chronic pituitary disorder. The delay in diagnosis results not only in unique somatic disfigurement but is also associated with significant mental and emotional dysfunction. This article reviews and describes some of these nonclassic and often overlooked featu...

journal_title：Endocrinology and metabolism clinics of North America

authors： Ezzat S

更新日期：1992-09-01 00:00:00

abstract：:Obesity in adults is associated with excess mortality and excess risk of coronary heart disease, hypertension, hyperlipidemia, diabetes, gallbladder disease, certain cancers, and osteoarthritis. Overweight children often become overweight adults, and overweight in adulthood is a health risk. Although childhood overwei...

journal_title：Endocrinology and metabolism clinics of North America

authors： Ogden CL,Carroll MD,Flegal KM

更新日期：2003-12-01 00:00:00

abstract：:Adrenal disorders may manifest during pregnancy de novo, or before pregnancy undiagnosed or diagnosed and treated. Adrenal disorders may present as hormonal hypofunction or hyperfunction, or with mass effects or other nonendocrine effects. Pregnancy presents special problems in the evaluation of the hypothalamic-pitui...

journal_title：Endocrinology and metabolism clinics of North America

authors： Abdelmannan D,Aron DC

更新日期：2011-12-01 00:00:00

abstract：:There are many pathways that might lead to decreased bone mass, skeletal fragility, and increased fracture risk in osteoporosis. Some of these have been clearly identified, such as estrogen deficiency. Others that were conceived on the basis of experimental findings and recent scientific discoveries such as abnormalit...

journal_title：Endocrinology and metabolism clinics of North America

authors： Raisz LG,Rodan GA

更新日期：2003-03-01 00:00:00

abstract：:Endocrinopathies are significant consequences of the treatment of childhood cancers. The risk of developing these adverse events is related to the underlying disease and its treatment with cytotoxic agents and radiation therapy. This article reviews hypothalamic-pituitary, thyroid, and gonadal dysfunction, as well as ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Cohen LE

更新日期：2005-09-01 00:00:00

abstract：:The goal of this article is to differentiate the insulin resistance syndrome from the metabolic syndrome. In the case of the insulin resistance syndrome, the abnormalities and clinical syndromes that are increased in prevalence in insulin-resistant individuals have been summarized, with a brief discussion of the causa...

journal_title：Endocrinology and metabolism clinics of North America

authors： Reaven G

更新日期：2004-06-01 00:00:00

abstract：:Renal artery stenosis, particularly related to advancing atherosclerotic disease, is a common concern to internists seeing patients with worsening hypertension and deteriorating renal function. Understanding the hormonal and hemodynamic consequences of critical vascular lesions allows better selection of antihypertens...

journal_title：Endocrinology and metabolism clinics of North America

authors： Textor SC

更新日期：1994-06-01 00:00:00

abstract：:This article addresses the role of insulin resistance in the pathogenesis of type 2 diabetes. The major causes of acquired insulin resistance including aging, pregnancy, lack of physical activity, and obesity are discussed briefly. The role of free fatty acids (FFAs) as a link between obesity and insulin resistance/ty...

journal_title：Endocrinology and metabolism clinics of North America

authors： Boden G

更新日期：2001-12-01 00:00:00

abstract：:The presence of vitamin D receptors in diverse tissues like immune cells, beta-cells in the pancreas, and cardiac myocytes has prompted research to evaluate the impact of vitamin D deficiency on the occurrence of immune diseases, diabetes, and cardiovascular disease (CVD). The expression of receptors not only in norma...

journal_title：Endocrinology and metabolism clinics of North America

authors： Wolden-Kirk H,Gysemans C,Verstuyf A,Mathieu C

更新日期：2012-09-01 00:00:00

abstract：:The 3243A>G mutation in mitochondrial DNA (mtDNA) is a genetic variant that is associated with a high risk of developing diabetes during life. Enhanced aging of pancreatic beta-cells, a reduced capacity of these cells to synthesize large amounts of insulin,and a resetting of the ATP/ADP-regulated K-channel seem to be ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Maassen JA,Jahangir Tafrechi RS,Janssen GM,Raap AK,Lemkes HH,'t Hart LM

更新日期：2006-06-01 00:00:00

abstract：:Adrenocortical carcinoma (ACC) is a rare and aggressive tumor. ACC may be associated with different syndromes of hormone excess, most frequently Cushing's syndrome with or without hypersecretion of androgens. Recent data suggest that cortisol excess is a negative prognostic factor in advanced and localized ACC. Surger...

journal_title：Endocrinology and metabolism clinics of North America

authors： Puglisi S,Perotti P,Pia A,Reimondo G,Terzolo M

更新日期：2018-06-01 00:00:00

abstract：:Elevated plasma concentrations of lipoprotein(a) (Lp[a]) are an emerging risk factor for the development of coronary heart disease (CHD). Recent genetic and epidemiologic data have provided strong evidence for a causal role of Lp(a) in CHD. Despite these developments, which have attracted increasing interest from clin...

journal_title：Endocrinology and metabolism clinics of North America

authors： Koschinsky ML,Boffa MB

更新日期：2014-12-01 00:00:00

abstract：:Medullary thyroid carcinoma (MTC) is a rare type of thyroid cancer, demonstrating variable behavior from indolent disease to highly aggressive, progressive disease. There are distinguishing phenotypic features of sporadic and hereditary MTC. Activation or overexpression of cell surface receptors and up-regulation of i...

journal_title：Endocrinology and metabolism clinics of North America

authors： Hu MI,Ying AK,Jimenez C

更新日期：2014-06-01 00:00:00

abstract：:Specific lesions of the growth hormone (GH)/insulin-like growth factor (IGF) axis have been identified in humans, each of which has distinctive auxologic and biochemical features. Measures of circulating IGF-I are useful in diagnosing growth disorders in childhood and in evaluating response to GH therapy. Recombinant ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Backeljauw PF,Chernausek SD

更新日期：2012-06-01 00:00:00

abstract：:Pheochromocytomas cause the most dramatic life-threatening crises in all of endocrinology. Pheochromocytoma is an explosive clinical syndrome that may be characterized by either severe hypertension associated with cerebral, cardiac, and renal complications or hypotension, or even shock and sudden death. Other emergenc...

journal_title：Endocrinology and metabolism clinics of North America

authors： Bravo EL,Gifford RW Jr

更新日期：1993-06-01 00:00:00

abstract：:Low-density lipoprotein cholesterol (LDL-C) level currently is used as the major determinant of lipid- and lipoprotein-associated risk for ischemic cardiovascular disease, and varying levels have become the standard goals of lipid-altering treatment. The predictive value of the LDL-C cholesterol level, however, often ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Lau JF,Smith DA

更新日期：2009-03-01 00:00:00

abstract：:The degree of hyperglycemia may be an important predictor of morbidity and mortality among patients with MI or stroke, and in those undergoing surgical procedures including coronary artery bypass. Hyperglycemia should be aggressively controlled from the time of hospital admission regardless of the patient's primary me...

journal_title：Endocrinology and metabolism clinics of North America

authors： Levetan CS,Magee MF

更新日期：2000-12-01 00:00:00

abstract：:Diseases in other organs may impair the male reproductive system. Acute critical conditions such as severe trauma, surgery, myocardial infarction, burns, liver failure, intoxication, or starvation are associated with suppression of gonadotropin secretion and secondary hypogonadism. With chronic illnesses, a primary te...

journal_title：Endocrinology and metabolism clinics of North America

authors： Baker HW

更新日期：1998-12-01 00:00:00

abstract：:Glucocorticoids mainly act through binding to cytosolic receptors that translocate to the nucleus after ligand binding, and dimerize to affect gene transcription in multiple fashions. The liganded receptors may interact with DNA at specific glucocorticoid responsive-elements, may physically hinder the ability of other...

journal_title：Endocrinology and metabolism clinics of North America

authors： Yanovski JA,Cutler GB Jr

更新日期：1994-09-01 00:00:00

abstract：:Historically, systemic therapies for advanced, metastatic thyroid carcinomas have been poorly effective. However, as a result of a confluence of increasing knowledge of the biologic basis for thyroid cancer development and progression, identification of therapeutic agents that could target these biologic abnormalities...

journal_title：Endocrinology and metabolism clinics of North America

authors： Sherman SI

更新日期：2008-06-01 00:00:00

abstract：:Nelson's syndrome (NS) is a condition which may develop in patients with Cushing's disease after bilateral adrenalectomy. Although there is no formal consensus on what defines NS, corticotroph tumor growth and/or gradually increasing ACTH levels are important diagnostic elements. Pathogenesis is unclear and well-estab...

journal_title：Endocrinology and metabolism clinics of North America

authors： Fountas A,Karavitaki N

更新日期：2020-09-01 00:00:00

abstract：:The regulation of energy balance is enormously complex, with numerous genetic, hormonal, neural/behavioral, and societal influences. Although the current epidemic of obesity has its underpinnings in the changes in culture during the last half century, the role of the neuroendocrine system in the genesis of obesity is ...

journal_title：Endocrinology and metabolism clinics of North America

authors： Lustig RH

更新日期：2001-09-01 00:00:00

abstract：:Thyroid nodules are extremely common, affecting from 4% to 7% of the population. Fine-needle aspiration biopsy is the most accurate and cost-effective technique for nodule diagnosis. It is simple, safe, and should be the first test used in patient work-up. Routine thyroxine (T4) suppressive therapy is no longer recomm...

journal_title：Endocrinology and metabolism clinics of North America

authors： Gharib H

更新日期：1997-12-01 00:00:00