Bone organic matrix components: their roles in skeletal physiology.

abstract：:Osteoporosis is a multifactorial chronic disease that may become even more prevalent and more of a public health problem in the decades to come. Recent research has indicated that a number of macro- and micronutrients are involved in the development of bone health. In the past decade it became evident that vitamin K p...

journal_title：Journal of endocrinological investigation

authors： Francucci CM,Rilli S,Fiscaletti P,Boscaro M

更新日期：2007-01-01 00:00:00

abstract：:Obesity and insulin resistance are common features of Type 2 Diabetes. A new protein called resistin has been shown to be secreted by adipocytes in mice and to influence insulin sensitivity. The goal of the present study was to investigate the associations between one polymorphism (g-420C>G) of the human resistin gene...

journal_title：Journal of endocrinological investigation

authors： Bouchard L,Weisnagel SJ,Engert JC,Hudson TJ,Bouchard C,Vohl MC,Pérusse L

更新日期：2004-12-01 00:00:00

abstract：:Puberty is a major developmental stage. Damaging mutations, considered as "mistakes of nature", have contributed to the unraveling of the networks implicated in the normal initiation of puberty. Genes involved in the abnormal hypothalamic-pituitary-gonadal (HPG) axis development, in the normosmic idiopathic hypogonado...

journal_title：Journal of endocrinological investigation

authors： Leka-Emiri S,Chrousos GP,Kanaka-Gantenbein C

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Neonatal hypothyroidism has serious effects on growth, development, and metabolism. AIM:This study aims to investigate the effects of the neonatal hypothyroidism on carbohydrate metabolism, islet insulin secretion and morphology of the pancreatic islets in adult male offspring. MATERIALS/SUBJECTS AND METHO...

journal_title：Journal of endocrinological investigation

authors： Farahani H,Ghasemi A,Roghani M,Zahediasl S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors determine a wide reduction of LDL cholesterol, greater than other lipid-lowering agents. The present meta-analysis is aimed at the assessment of PCSK9 inhibitors effect on LDL Cholesterol, cardiovascular morbidity and all-cause mortali...

journal_title：Journal of endocrinological investigation

authors： Dicembrini I,Giannini S,Ragghianti B,Mannucci E,Monami M

更新日期：2019-09-01 00:00:00

abstract：:We report the case of a 17-year-old girl presenting short stature (height 149 cm, below the 3rd percentile), obesity (weight 83.5 kg, body mass index 37 kg/m2) and secondary amenorrhea, in whom endocrinological evaluation disclosed an absolute lack of GH responsiveness to both suprapituitary challenges and repetitive ...

journal_title：Journal of endocrinological investigation

authors： Scacchi M,Alé G,Silvestri P,Cavagnini F

更新日期：1995-05-01 00:00:00

abstract：PURPOSE:Although men with spinal cord injury (SCI) exhibit a prostate volume significantly smaller compared to age-matched able-bodied men, the independent association of lower prostate volume with its putative determinants has never been analyzed in this population. This study was designed to identify variables indepe...

journal_title：Journal of endocrinological investigation

authors： D'Andrea S,Castellini C,Minaldi E,Totaro M,Felzani G,Francavilla S,Francavilla F,Barbonetti A

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The Middle East registers the highest rate of vitamin D deficiency worldwide. In Lebanon, previous studies looked at this deficiency in schoolchildren, university students, young adults and postmenopausal women. However, no previous study was performed in hospital workers. The objective of our study was to e...

journal_title：Journal of endocrinological investigation

authors： Gannagé-Yared MH,Helou E,Zaraket V,Abi Akl S,Antonios L,Moussalli ML,Wakim S

更新日期：2014-06-01 00:00:00

abstract：:It has recently been suggested that the classical routine of glucocorticoid administration before and after transsphenoidal surgery (TSS) in Cushing's disease (CD) patients may not be necessary, since it is likely that peritumoral normal corticotrophs are not completely suppressed during this period. We compared the d...

journal_title：Journal of endocrinological investigation

authors： Pimentel-Filho FR,Silva ME,Nogueira KC,Berger K,Cukiert A,Liberman B

更新日期：2005-06-01 00:00:00

abstract：:The case is described of a woman with a Verner-Morrison syndrome of extreme severity, caused by an occult VIPoma. Administration of SMS 201-995 (Sandoz) (SMS) at the dose of 150 and subsequently of 250 micrograms daily, decreased plasma levels of vasoactive intestinal polypeptide (VIP) from about 500 to 100 pg/ml (hig...

journal_title：Journal of endocrinological investigation

authors： Brunani A,Crespi C,De Martin M,Dubini A,Piolini M,Cavagnini F

更新日期：1991-09-01 00:00:00

abstract：:The occurrence of tumors originating from aberrant adrenocortical tissue in ectopic site is very rare. Up to now only two cases of ectopic aldosterone-producing adenoma have been described. We have observed another case of ectopic aldosteronoma, located in the retrocaval region, laterally to the body of the 12th thora...

journal_title：Journal of endocrinological investigation

authors： Mazza E,Papotti M,Durando R,Robecchi A,Camanni F

更新日期：1995-11-01 00:00:00

abstract：:Lipopolysaccharide (LPS)-induced inflammatory stress activates the hypothalamus-pituitary-adrenal (HPA) function. Interleukin-I (IL-1) is one of the key factors during this event; however, the mechanisms mediating IL-1 stimulation of HPA axis are still unclear. The present study evaluated the possible involvement of g...

journal_title：Journal of endocrinological investigation

authors： Guo AL,Petraglia F,Nappi RE,Criscuolo M,Ficarra G,Salvestroni C,Genazzani AD,Trentini GP,Genazzani AR

更新日期：1996-02-01 00:00:00

abstract：:A 52-year-old male presented himself with tachycardia crises which appeared first during childhood, increased in frequency without goiter or exophthalmos. Cardiac and adrenergic diseases were excluded. The thyroid function was normal regarding T4, free T4 and T3, TBG, radioiodine uptake, TSH and T3 suppressibility; ho...

journal_title：Journal of endocrinological investigation

authors： Jaffiol C,Baldet L,Torresani J,Bismuth J,Papachristou C

更新日期：1990-11-01 00:00:00

abstract：:A 50 year old man is described in whom primary hypothyroidism and isolated ACTH deficiency leading to adrenocortical insufficiency occurred simultaneously. Low thyroid hormone levels, elevated serum TSH values and high titers of antithyroid antibodies (ATA) were consistent with primary hypothyroidism. The diagnosis of...

journal_title：Journal of endocrinological investigation

authors： Roosens B,Maes E,Van Steirteghem A,Vanhaelst L

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Several studies investigated the possible role of adipokines during chronic viral hepatitis, not producing defined results neither clearly establishing their behavior in course of anti-viral treatment. Our study evaluated blood concentrations of adiponectin and resistin in patients with chronic hepa...

journal_title：Journal of endocrinological investigation

authors： Durazzo M,Belci P,Niro G,Collo A,Grisoglio E,Ambrogio V,Spandre M,Fontana R,Gambino R,Cassader M,Bo S

更新日期：2013-09-01 00:00:00

abstract：:The effects of growth hormone-releasing hormone (GHRH) were studied on densely granulated somatotroph adenoma cells and sparsely granulated somatotroph adenoma cells in culture by measuring release of growth hormone (GH) as well as ultrastructural morphometrical parameters and comparing them with those of control aden...

journal_title：Journal of endocrinological investigation

authors： Kawakita S,Asa SL,Kovacs K

更新日期：1989-07-01 00:00:00

abstract：:Following presentation and diagnosis, microprolactinomas usually follow a benign course and rarely progress to macroprolactinomas. However, clinically significant enlargement of prolactinomas during pregnancy, presumably related to estrogen stimulation, has been reported. This report describes a patient with amenorrhe...

journal_title：Journal of endocrinological investigation

authors： Garcia MM,Kapcala LP

更新日期：1995-06-01 00:00:00

abstract：INTRODUCTION:Insulinomas are a rare type of pancreatic neuroendocrine tumours characterized by insulin hypersecretion. They are considered malignant when metastases are present. Traditional therapies often promote only temporarily symptomatic relief and may be associated with severe adverse effects. There is scarce exp...

journal_title：Journal of endocrinological investigation

authors： Magalhães D,Sampaio IL,Ferreira G,Bogalho P,Martins-Branco D,Santos R,Duarte H

更新日期：2019-03-01 00:00:00

abstract：:Hypocalcemia associated with labor and lactation is a rare condition reported previously in patients with hypovitaminosis D. We here describe a case of a young woman in whom symptomatic severe hypocalcemia appeared after her second delivery, early in lactation. At the end of lactation the condition worsened. We review...

journal_title：Journal of endocrinological investigation

authors： Durst R,Meirovitz A,Gross D,Kolker O,Muszkat M

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:Thyroid hormone resistance (RTH β) is a rare genetic disorder characterized by an altered response of target tissue to the action of thyroid hormone. Few studies on RTH β have been carried out in southern European populations. We aimed to describe the clinical and genetic characteristics at the time of diagno...

journal_title：Journal of endocrinological investigation

authors： Vela A,Pérez-Nanclares G,Ríos I,Rica I,Portillo N,Castaño L,Spanish Group for the Study of RTH.

更新日期：2019-08-01 00:00:00

abstract：:This study examined the association of depression, anxiety, and stress with Type 2 diabetes (T2DM) in Bahrain, an island-country with a very high prevalence of T2DM. This was a cross-sectional study involving administering Depression Anxiety Stress Scales (DASS)-21 structured depression, anxiety, and stress scale to 1...

journal_title：Journal of endocrinological investigation

authors： Almawi W,Tamim H,Al-Sayed N,Arekat MR,Al-Khateeb GM,Baqer A,Tutanji H,Kamel C

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:The determination of (a) iodine deficiency, and (b) the relation between the iodized salt consumption in the Isparta province of Turkey. METHODS:Five hundred students between 6-11 yr of age were evaluated. With a questionnaire, the subjects were asked whether they were using iodine-containing salt or not. Af...

journal_title：Journal of endocrinological investigation

authors： Cetin H,Kisioglu AN,Gursoy A,Bilaloglu E,Ayata A

更新日期：2006-09-01 00:00:00

abstract：:In order to investigate the effect of gender, age and level of obesity on body composition and anaerobic power output, and to test the hypothesis that variation in body composition affects muscle power output in obesity, a cohort of 377 subjects (112 males and 265 females, aged 18-75 yr) with different levels of obesi...

journal_title：Journal of endocrinological investigation

authors： Lafortuna CL,Agosti F,Marinone PG,Marazzi N,Sartorio A

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:To investigate the effects of metabolic abnormalities, hyperandrogenemia and ovulation induction by clomiphene/acupuncture on liver function parameters among women with polycystic ovary syndrome (PCOS). METHODS:This is a secondary analysis of a randomized controlled trial. All 1000 subjects were diagnosed as P...

journal_title：Journal of endocrinological investigation

authors： Cai WY,Gao JS,Luo X,Ma HL,Ge H,Liu N,Xia Q,Wang Y,Han BW,Wu XK

更新日期：2019-05-01 00:00:00

abstract：:In order to precise the relationships between TSH, FT3, and FT4 nycthemeral variations and the relationships between thyroid hormone variations and sleep, 8 healthy young males were studied twice, once during a 24-h experiment with normal nocturnal sleep, and once during a night of sleep deprivation. The subjects rece...

journal_title：Journal of endocrinological investigation

authors： Goichot B,Brandenberger G,Saini J,Wittersheim G,Follenius M

更新日期：1994-03-01 00:00:00

abstract：:It has been shown that the antithyroid drug methimazole (MMI) may affect B cells and possibly accessory cell function. In the present study we investigated in detail the effects of MMI on T cell in vitro proliferation. The following variables were evaluated: T cell proliferation following stimulation with phytohemaggl...

journal_title：Journal of endocrinological investigation

authors： Bagnasco M,Venuti D,Ciprandi G,Pesce G,Paolieri F,Canonica GW

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The adiponectin gene has been identified as a susceptibility locus for metabolic syndrome, diabetes and cardiovascular disease. AIM:To examine the influence of two single nucleotide polymorphisms (SNPs) of this gene (+276G>T and +45T>G) on circulating adiponectin concentrations, and to evaluate their relati...

journal_title：Journal of endocrinological investigation

authors： Galcheva SV,Martorana D,Iotova VM,Yotov Y,Neri TM,Street ME

更新日期：2013-11-01 00:00:00

abstract：:The autosomal dominant familial neurohypophyseal diabetes insipidus (adFNDI) is caused by diverse mutations in one allele of the gene that encodes the arginine vasopressin (AVP) precursor protein, AVP-neurophysin II (AVP-NP II). Most of the mutations identified so far are located in either the signal peptide or NP II ...

journal_title：Journal of endocrinological investigation

authors： Kobayashi H,Fujisawa I,Ikeda K,Son C,Iwakura T,Yoshimoto A,Kasahara M,Ishihara T,Ogawa Y

更新日期：2006-03-01 00:00:00

abstract：:Signals that determine skeletal cell fate, function and apoptosis are critical to normal bone remodeling. Skeletal cells synthesize growth factors; some regulate cell replication, others regulate osteoblastic differentiation. Bone morphogenetic proteins (BMP) and Wnts induce the differentiation of mesenchymal cells to...

journal_title：Journal of endocrinological investigation

authors： Canalis E,Deregowski V,Pereira RC,Gazzerro E

更新日期：2005-01-01 00:00:00

abstract：:The aim of this prospective study was to investigate the effects of thyroid hormone levels on the sepsis criteria and mortality in septic newborns. This study was performed at the Firat University Hospital Neonatal Intensive Care Unit. A group of septic newborns and a control group of healthy non-infected newborns wer...

journal_title：Journal of endocrinological investigation

authors： Kurt A,Aygun AD,Sengul I,Sen Y,Citak Kurt AN,Ustundag B

更新日期：2011-04-01 00:00:00