Abstract:
:Genetic diversity indices and forensic parameters at 20 autosomal short tandem repeat (STR) loci were evaluated in 233 unrelated individuals of Himachal Pradesh, India. In total, 255 alleles were observed with an average of 11.25 ± 0.88 alleles per locus. None of the loci deviated from Hardy Weinberg Equilibrium. The most polymorphic and discriminative locus was Penta E. The combined power of exclusion and the combined power of discrimination were found to be 0.99 and 1. Additionally, the genetic relationship of the Himachal Pradesh population with the populations of the neighboring state was also investigated. All the STR loci were found polymorphic, and the select panel of STRs was found suitable for population genetic studies and forensic analysis.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Sahajpal V,Singh A,Thakur M,Sharma A,Bhandari D,Sharma LK,Chandra K,Kumar Sdoi
10.1007/s00414-020-02254-8subject
Has Abstractpub_date
2020-09-01 00:00:00pages
1663-1666issue
5eissn
0937-9827issn
1437-1596pii
10.1007/s00414-020-02254-8journal_volume
134pub_type
杂志文章abstract::This paper reports population data and statistics for the HumFES/FPS, HumVWA, HumFGA and D12S391 loci in Austria. The sequences of some rare and new variant alleles which have been identified in the course of the present population study and other investigations are described. Sequence variation occurred in a HumFES/F...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/pl00007712
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:The response to traumatic brain injury (TBI) is complex and induces various biological pathways in all brain regions that contribute to bad outcomes. The cerebellar hypoxia after a frontal cortex injury may potentiate the pathophysiological impacts of TBI. Therefore, a gene expression analysis was conducted to ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1129-3
更新日期:2015-07-01 00:00:00
abstract::For the interpretation of the concentration of morphine in blood samples of heroin consumers information about the concentration of the analgesic active morphine metabolite morphine-6-glucuronide is very important. Thus a simple but specific clean-up procedure based on immuno-affinity chromatography is presented for t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
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abstract::In this casuistry, two accidents from Germany and Switzerland are presented that happened during the shot of recoilless anti-tank weapons. In both cases, the injuries led to the death of two soldiers: A 22-year-old soldier in Germany was struck by the counter mass of a so-called Davis gun which had been fired by a com...
journal_title:International journal of legal medicine
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doi:10.1007/s00414-020-02301-4
更新日期:2020-11-01 00:00:00
abstract::One of the most common conditions during fetal development is anencephaly, which often involves many identification difficulties in the context of physical anthropology, as it causes severe skull challenges. In this paper, we describe the alterations found in the skulls of two perinatal individuals with anencephaly fr...
journal_title:International journal of legal medicine
pub_type: 杂志文章
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更新日期:2015-07-01 00:00:00
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journal_title:International journal of legal medicine
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更新日期:2010-11-01 00:00:00
abstract::Sexual assault is a complex situation with medical, psychological, and legal aspects. Forensic experts play a major role in terms of forensic and gynecological medical examination and evidence collection in order to maintain the chain of custody. Victims should be examined by a specially trained medico-legal examiner ...
journal_title:International journal of legal medicine
pub_type: 杂志文章,实务指引
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更新日期:2018-11-01 00:00:00
abstract::Population genetic studies were carried out on 932 caucasians from Austria using the short tandem repeat system ACTBP2 (SEE33). A sequenced allelic ladder was used for typing (Möller et al. 1995). After native polyacrylamide gel electrophoresis all 26 alleles of the ladder were found as well as 194 alleles which migra...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050111
更新日期:1998-01-01 00:00:00
abstract::The forensic application of mtDNA typing requires large databases which are regionally well defined. To further this aim, we have typed mtDNA in a sample of 111 French and 106 Sicilians. The French were typed for both hypervariable segments (HVR1 and HVR2) of the mtDNA control region, whereas the Sicilians were only t...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140000169
更新日期:2001-01-01 00:00:00
abstract::During forensic investigations, it is often important to be able to distinguish between impact spatter patterns (blood from gunshots, explosives, blunt force trauma and/or machinery accidents) and bloodstain patterns generated by expiration (blood from the mouth, nose or lungs). These patterns can be difficult to dist...
journal_title:International journal of legal medicine
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更新日期:2011-11-01 00:00:00
abstract::In a Japanese population study of the D1S80 locus 24 alleles ranging from allele 16 to allele43 were analysed using PCR-RFLP. As two repeat units were found to contain the restriction cleavage site (CCAGG) for EcoRII, we digested the alleles with EcoRII, separated the digested fragments on polyacrylamide gels and stai...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050146
更新日期:1998-01-01 00:00:00
abstract::A system of nomenclature is proposed for the complex STR system ACTBP2 (SE33) in order to facilitate data exchange between laboratories. The nomenclature conforms to the ISFH recommendations as far as it is possible for such complex systems. A blind trial was carried out between up to 20 laboratories to ascertain the ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050124
更新日期:1998-01-01 00:00:00
abstract::Messenger RNA (mRNA) markers have been extensively investigated for the identification of forensically relevant body fluids and tissues based on their expression profiles among cell types. As products of the backsplicing of pre-mRNAs, circular RNAs (circRNAs) share exonic sequences with their linear counterparts. The ...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-019-02027-y
更新日期:2019-09-01 00:00:00
abstract::In the immigration case cited by Jeffreys et al. (1985), the biostatistical evaluation of blood group findings in 16 systems and of HLA-A,B findings for the mother and child, using a special kinship algorithm developed by Ihm and Hummel (1975), produced a probability of maternity of the Ghanaian-born putative mother o...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01371238
更新日期:1992-01-01 00:00:00
abstract::The alcoholism marker CDT was determined on 257 blood samples 1-2 days after the blood samples were taken and again after storage for 7 months at +4 degrees C. The differences between the pairs of CDT values were so large that the determination of CDT after long term storage of the blood sample has no evidential value...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050013
更新日期:2000-01-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-006-0078-x
更新日期:2007-07-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-016-1377-5
更新日期:2016-11-01 00:00:00
abstract::Determination of electrolyte concentrations (mainly potassium) in vitreous humour has long been considered an important tool in human death investigations for the estimation of the post-mortem interval (PMI). On the basis of its well known potential in ion analysis, capillary zone electrophoresis (CZE) has recently be...
journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140100239
更新日期:2002-02-01 00:00:00
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journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01428399
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journal_title:International journal of legal medicine
pub_type: 杂志文章
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更新日期:2007-11-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/BF01355519
更新日期:1996-01-01 00:00:00
abstract::The craniofacial superimposition technique is still an important way of identifying skulls when there is no reference sample for a forensic DNA analysis, when DNA typing from remaining tissue samples has failed, or when antemortem dental records are not available. Through the widespread use of digital photography, the...
journal_title:International journal of legal medicine
pub_type: 杂志文章
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更新日期:2010-09-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s004140050101
更新日期:1998-01-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-014-1028-7
更新日期:2015-01-01 00:00:00
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journal_title:International journal of legal medicine
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