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Liver transplantation for acute liver failure: the Hungarian experience.

Abstract：

:Acute liver failure (ALF) counts for 9%-11% of activity in leading liver transplant programs. We have summarized the Hungarian Liver Transplant Program experience for ALF among 412 consecutive orthotopic liver transplantations (OLTs). All OLTs were performed without an extended international donor background. The proportion of ALF among the indications for OLT was lower (5.8% vs 9%) and early mortality higher than the European Liver Transplant Registry (1 year cumulative patients survival is 70% in ELTR vs 60% in the HU LT Program). The waiting time for a donor was longer than expected in the Eurotransplant community. Regarding postoperative complications, there was a higher incidence of initial poor function, bacterial infection, sepsis, and multiorgan failure. We conclude that ALF can be managed with reasonable results but requires an extended donor pool with an integrated international network to improve postoperative morbidity and mortality.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Nemes B,Zádori G,Görög D,Fehérvári I,Kóbori L,Langer RM

doi

10.1016/j.transproceed.2011.03.076

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

1278-80

issue

4

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(11)00591-4

journal_volume

43

pub_type

杂志文章

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