Abstract:
OBJECTIVES:To explore the roles of pain and urgency in the nocturia of patients with interstitial cystitis/painful bladder syndrome (IC/PBS). METHODS:In a longitudinal study of incident IC/PBS cases, we assessed the associations of the presence and severity of nocturia with the presence and severity of pain and urgency, using multivariate analyses when necessary. Additionally, we simply asked patients with IC/PBS what awakens them at night. RESULTS:The multivariate analyses revealed associations of urgency with the presence and severity of nocturia and of bladder pain with the severity of nocturia. Direct queries of patients with IC/PBS about urgency and the reasons for awakening demonstrated that bladder pain might have played a twofold role: directly in awakening a large minority of patients and possibly indirectly in the majority by generating the sensation of urgency. CONCLUSIONS:These findings are consistent with urinary urgency and bladder pain each being in the causal pathway leading to nocturia in patients with IC/PBS.
journal_name
Urologyjournal_title
Urologyauthors
Warren JW,Horne L,Diggs C,Greenberg P,Langenberg PWdoi
10.1016/j.urology.2011.02.012subject
Has Abstractpub_date
2011-06-01 00:00:00pages
1308-12issue
6eissn
0090-4295issn
1527-9995pii
S0090-4295(11)00159-2journal_volume
77pub_type
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