Abstract:
:In this work we address the use of realtime cortical recordings for the generation of coherent, reliable and robust motor activity in spinal-lesioned animals through selective intraspinal microstimulation (ISMS). The spinal cord of adult rats was hemisectioned and groups of multielectrodes were implanted in both the central nervous system (CNS) and the spinal cord below the lesion level to establish a neural system interface (NSI). To test the reliability of this new NSI connection, highly repeatable neural responses recorded from the CNS were used as a pattern generator of an open-loop control strategy for selective ISMS of the spinal motoneurons. Our experimental procedure avoided the spontaneous non-controlled and non-repeatable neural activity that could have generated spurious ISMS and the consequent undesired muscle contractions. Combinations of complex CNS patterns generated precisely coordinated, reliable and robust motor actions.
journal_name
J Neural Engjournal_title
Journal of neural engineeringauthors
Panetsos F,Sanchez-Jimenez A,Torets C,Largo C,Micera Sdoi
10.1088/1741-2560/8/4/046008subject
Has Abstractpub_date
2011-08-01 00:00:00pages
046008issue
4eissn
1741-2560issn
1741-2552pii
S1741-2560(11)82339-6journal_volume
8pub_type
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更新日期:2013-12-01 00:00:00
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更新日期:2010-06-01 00:00:00
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更新日期:2018-04-01 00:00:00
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更新日期:2019-02-01 00:00:00
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更新日期:2013-08-01 00:00:00
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更新日期:2019-02-01 00:00:00
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更新日期:2020-04-09 00:00:00
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pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
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更新日期:2019-10-10 00:00:00
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更新日期:2018-10-01 00:00:00
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更新日期:2020-05-07 00:00:00
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journal_title:Journal of neural engineering
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更新日期:2012-12-01 00:00:00
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更新日期:2020-06-02 00:00:00