Abstract:
BACKGROUND AND PURPOSE:Based on thrombus location and nature and anatomic features of aorta and cerebral arteries, we hypothesized that cardiogenic embolisms (CE) and aortogenic embolisms (AE) might have different right-left propensity and lesion patterns. METHODS:We retrospectively reviewed patients with acute ischemic stroke with high-risk CE sources or moderate-or-severe aortic atherosclerotic plaques on transesophageal echocardiography. Lesion side and patterns on diffusion-weighted imaging were compared between CE and AE. RESULTS:CE was identified in 123 and AE in 63. In multivariate analysis, right-sided lesions and corticosubcortical infarcts were independently associated with CE, and left-sided lesions and pial infarcts were independently associated with AE. CONCLUSIONS:CE and AE have different radiological characteristics, as shown by the right-left propensity and lesions patterns of cerebral infarcts.
journal_name
Strokejournal_title
Strokeauthors
Kim HJ,Song JM,Kwon SU,Kim BJ,Kang DH,Song JK,Kim JS,Kang DWdoi
10.1161/STROKEAHA.111.616573subject
Has Abstractpub_date
2011-08-01 00:00:00pages
2323-5issue
8eissn
0039-2499issn
1524-4628pii
STROKEAHA.111.616573journal_volume
42pub_type
杂志文章相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:Identification of acute ischemic stroke (AIS) cause is crucial for guidance of secondary prevention. Previous studies have yielded inconsistent results regarding possible correlations between AIS cause and thrombus composition, as assessed by semiquantitative histological analysis. Here, we perfo...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.120.029134
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The relationship between the pattern of alcohol intake and the risk of stroke is unclear, in particular the increased risk observed in abstainers and the possible protective effect of light to moderate drinking. For that reason, we examined in a large prospective study the role of alcohol consump...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.6.1033
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Apoptotic-like pathways may contribute to brain cell death after intracerebral hemorrhage. In this study, we used a simplified in vitro model of hemoglobin neurotoxicity to map the caspase cascades involved and to document the role of oxidative stress. METHODS:Primary neuronal cultures were obta...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.0000020121.41527.5d
更新日期:2002-07-01 00:00:00
abstract::A standardized neurologic assessment scoring instrument was developed and tested for use in a multicenter trial of hypervolemic hemodilution in acute hemispheric stroke. Components of the neurologic examination pertinent to hemispheric stroke syndromes were emphasized. The scale was evaluated using 16 acute stroke pat...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.3.665
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Inflammation is thought to be a major contributor to carotid artery disease. Lipopolysaccharide (LPS) activates inflammatory mechanisms thought to contribute to endothelial dysfunction by mechanisms that are not well defined. The goal of this study was to determine whether overexpression of CuZn-...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000132764.06878.c5
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Intraventricular thrombolysis (IVT) is a promising treatment in facilitating intraventricular clot resolution after intraventricular hemorrhage. We examined in-hospital outcomes and resource utilization after thrombolysis in patients with intraventricular hemorrhage requiring ventriculostomy in a...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.114.006067
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We aim to investigate whether histopathologic examination of thrombi retrieved from acute ischemic stroke patients undergoing endovascular treatment could distinguish cancer-related stroke from other etiologies. METHODS:Thrombi from patients undergoing endovascular treatment were analyzed. The e...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.120.032069
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Although the modified Rankin Scale (mRS) is the most commonly used primary end point in acute stroke trials, its power is limited when analyzed in dichotomized fashion and its indication of effect size challenging to interpret when analyzed ordinally. Weighting the 7 Rankin levels by utilities ma...
journal_title:Stroke
pub_type: 杂志文章,meta分析
doi:10.1161/STROKEAHA.114.008547
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Iron overload has been associated with greater oxidative stress and brain injury in experimental cerebral ischemia and reperfusion. This study investigates whether high serum ferritin levels, as an index of increased cellular iron stores, are associated with poor outcome, hemorrhagic transformati...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/01.STR.0000251798.25803.e0
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I). We tested the hypothesis that topical pretreatment with the selective potassium channel agonists NS1619 and aprikalim preserves the vasc...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.29.4.837
更新日期:1998-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral autoregulation may be impaired in the early days after subarachnoid hemorrhage (SAH). The purpose of this study was to examine the relationship between cerebral autoregulation and angiographic vasospasm (aVSP) and radiographic delayed cerebral ischemia (DCI) in patients with SAH. METHOD...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.002630
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The pressure-flow relation has been characterized in normal cerebrum, but it has not been studied in cerebrum dependent on collateral flow. The purpose of this investigation was to examine the relation between systemic pressure, regional cerebral blood flow, and middle cerebral artery branch pres...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.7.988
更新日期:1992-07-01 00:00:00
abstract::The effects of hypoxic hypoxia on cerebral hemodynamics and somatosensory evoked potential (SEP) were studied in 10 pentobarbital anestheteized dogs. Cerebral blood flow (CBF) was measured using the venous outflow technique and cerebral oxygen consumption (CMRO2) was calculated from the arterio-cerebro-venous oxygen d...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.1.30
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We have investigated the pathophysiological mechanisms of dysphagia in Wallenberg's syndrome (WS) that are due to lateral medullary infarction (LMI). METHODS:Twenty patients with WS were evaluated by means of clinical and electrophysiological methods that measured the oropharyngeal phase of volu...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/hs0901.094278
更新日期:2001-09-01 00:00:00
abstract::Background and Purpose- We aimed to determine whether low-frequency electric field navigated repetitive transcranial magnetic stimulation to noninjured motor cortex versus sham repetitive transcranial magnetic stimulation avoiding motor cortex could improve arm motor function in hemiplegic stroke patients when combine...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.117.020607
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Previous studies have evaluated the association of body mass index (BMI) with the risk of all-cause and cardiovascular disease mortality among diabetic patients, and results were controversial. No studies have focused on the association between BMI and stroke risk among diabetic patients. We aime...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.114.006718
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Central nervous system serotonergic neurotransmission appears to play a role in mood disorders, eating habits, and sleep, and also modulates blood pressure and metabolism. This investigation tested a hypothesized association between central serotonergic functioning and preclinical atherosclerosis...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.106.477638
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Patients with arteriovenous malformations are younger individuals who are at risk of a stroke or have experienced one. Our objective was to determine these patients' perceptions of quality of life with a stroke by eliciting utility values. METHODS:Utility values were obtained with the standard g...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.str.28.12.2395
更新日期:1997-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We evaluated the impact of lifestyle factors on the risk of ischemic stroke. METHODS:We used a nested case-control design. The cases comprised 163 persons (median age 69 years) admitted to a stroke unit and diagnosed with acute cerebral infarction. All cases had earlier participated in the North...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.6.829
更新日期:1992-06-01 00:00:00
abstract::Although the blood flow tracer hexamethylpropyleneamine oxime is now widely used for cerebral blood flow mapping using single-photon emission computed tomography, its uptake into acutely ischemic brain has not been well studied. We performed a double-label autoradiographic study in which 99mTc-hexamethylpropyleneamine...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.10.1284
更新日期:1991-10-01 00:00:00
abstract::This study was conducted to determine whether air distributed to the cerebral circulation alone could cause acute cardiovascular dysfunction and thus be a potential mechanism for sudden death following arterial air embolism. Cardiovascular measurements were made in anesthetized, ventilated cats during infusion of air ...
journal_title:Stroke
pub_type: 杂志文章
doi:
更新日期:1981-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:[18F]fluoromisonidazole (FMISO) positron emission tomography has been used to image hypoxia early after human stroke. To further study the role of hypoxia in stroke and the binding characteristics of FMISO, we aimed to develop [3H]FMISO autoradiography in an animal stroke model. We hypothesized t...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000226908.93295.9d
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:To verify the hemorheological effects of isovolemic hemodilution on hemodynamics and cerebral perfusion of normal humans, we tested the efficacy of isovolemic hemodilution in systemic hemodynamics and cerebral bood flow augmentation and its influences in vascular reserve. METHODS:Isovolemic hemo...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.3.441
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Intracranial arterial dolichoectasia (IADE) is a poorly understood arteriopathy compared with intracranial atherosclerotic stenosis (ICAS). We aimed to investigate the risk factors of IADE and ICAS and their relationship with neuroimaging markers of cerebral small vessel disease in a population-b...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.020130
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In ischemic stroke, diffusion-weighted (DW) and perfusion-weighted (PW) magnet resonance imaging (MRI) is used to define the mismatch as the therapeutic target. With positron emission tomography (PET), we characterized the metabolic patterns of tissue compartments identified by MRI and compared t...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000160751.79241.a3
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) is associated with a temporal pattern of stroke incidence. We hypothesized that natural oscillations in gene expression controlling circadian rhythm affect the severity of neuronal injury. We moreover predict that heme oxygenase-1 (HO-1/Hmox1) and its product carbon ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.016165
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Fish consumption has been postulated to reduce the risk of stroke. We conducted a dose-response meta-analysis to summarize the evidence from prospective studies regarding the association between fish consumption and stroke risk. METHODS:Pertinent studies were identified by searching Embase and P...
journal_title:Stroke
pub_type: 杂志文章,meta分析
doi:10.1161/STROKEAHA.111.630319
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Toll-like receptors (TLRs) and the scavenger receptor CD36 are key molecular sensors for the innate immune response to invading pathogens. However, these receptors may also recognize endogenous "danger signals" generated during brain injury, such as cerebral ischemia, and trigger a maladaptive in...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.572552
更新日期:2010-05-01 00:00:00
abstract::Background and Purpose- Carotid web (CW) is a rare form of focal fibromuscular dysplasia defined as an abnormal shelf-like projection of intimal fibrous tissue into the carotid bulb. It is theorized that CW leads to ischemic stroke secondary to blood flow stasis and subsequent embolization. The natural history and opt...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.021907
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:After stroke, individuals have decreased mobility of the hemiparetic leg, which demands less muscle oxygen consumption; thus, blood flow decreases. The purpose of this study was to determine the effect of single limb exercise (SLE) on femoral artery blood flow, diameter, and peak flow velocity in...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/STROKEAHA.109.550889
更新日期:2009-09-01 00:00:00