Abstract:
AIMS:We investigated the 2-year clinical outcomes of patients with acute myocardial infarction (AMI) and prediabetes after new-generation drug-eluting stents implantation. METHODS:A total of 11,962 patients with AMI were classified into normoglycemia (group A; 3,080), prediabetes (group B; 3,709), and diabetes (group C; 5,173) groups. The primary outcomes were the patient-oriented composite outcomes (POCOs) defined as all-cause death, recurrent myocardial infarction (Re-MI), and any repeat revascularization. Secondary outcomes were the individual components of POCOs and stent thrombosis (ST). RESULTS:POCOs in groups B and C were significantly higher than those in group A. Cardiac death (adjusted hazard ratio [aHR]: 1.957, 95% confidence interval [CI]: 1.126-3.402; p = 0.017) and any repeat revascularization (aHR: 1.597, 95% CI: 1.052-2.424; p = 0.028) rates were significantly higher in group B than in group A. Re-MI (aHR: 1.884, 95% CI: 1.201-2.954; p = 0.006) and death or MI (aHR: 1.438, 95% CI: 1.098-1.884; p = 0.008) were significantly higher in group C than in group B. CONCLUSIONS:In this study, prediabetes showed bad clinical outcomes post AMI. However, larger randomized controlled studies including ethnically diverse population are needed to confirm these harmful cardiovascular effects of prediabetes in the future.
journal_name
Diabetes Res Clin Practjournal_title
Diabetes research and clinical practiceauthors
Kim YH,Her AY,Jeong MH,Kim BK,Hong SJ,Kim S,Ahn CM,Kim JS,Ko YG,Choi D,Hong MK,Jang Ydoi
10.1016/j.diabres.2019.107994subject
Has Abstractpub_date
2020-02-01 00:00:00pages
107994eissn
0168-8227issn
1872-8227pii
S0168-8227(19)31526-8journal_volume
160pub_type
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2011.02.023
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,多中心研究
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,评审
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,评审
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更新日期:1996-07-01 00:00:00
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
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journal_title:Diabetes research and clinical practice
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2009.03.002
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.diabres.2017.02.010
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journal_title:Diabetes research and clinical practice
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doi:10.1016/j.diabres.2006.07.010
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
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更新日期:2008-04-01 00:00:00
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2016.06.005
更新日期:2016-08-01 00:00:00
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,多中心研究
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更新日期:2002-07-01 00:00:00
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2006.10.017
更新日期:2007-07-01 00:00:00
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/s0168-8227(87)80058-x
更新日期:1987-11-01 00:00:00
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2018.07.038
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2004.02.020
更新日期:2004-10-01 00:00:00
abstract:AIMS:This study aims to examine the prevalence, associated risk factors and complications of diabetes, as well management and preventive care in Lebanon, a small, middle-income country of the Mediterranean region. METHODS:Using a comprehensive multi-dimensional questionnaire, a cross-sectional national survey of 2195 ...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2014.06.005
更新日期:2014-09-01 00:00:00
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journal_title:Diabetes research and clinical practice
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1989-02-15 00:00:00
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journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00