Abstract:
:Coatings of biomaterials or implants that facilitate biomineralization possess a great potential for applications focused to the replacement, augmentation, and regeneration of bone tissue. Biomimetic approaches utilize biomolecules for either templating or supporting the crystallization process. One of these promising biomolecules is phosvitin (PV), an egg yolk protein known to transport and store inorganic phosphates and calcium ions. The incorporation of PV into polyelectrolyte multilayers is favorable due to PVs high degree of phosphorylation and thus a high acidity. Utilizing the reflectometric interference spectroscopy, the adsorption kinetics of this novel polyelectrolyte system composed of poly-L-lysine and the heavily phosphorylated phosvitin were monitored. The results demonstrate an unexpected nonregular growth regime called overshoot. Effective measures of shifting this irregular polyelectrolyte adsorption process back to a regular multilayer growth regime are reported in this paper.
journal_name
Biointerphasesjournal_title
Biointerphasesauthors
Grohmann S,Rothe H,Eisenhuth S,Hoffmann C,Liefeith Kdoi
10.1116/1.3589176subject
Has Abstractpub_date
2011-06-01 00:00:00pages
54-62issue
2eissn
1934-8630issn
1559-4106journal_volume
6pub_type
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