Abstract：
OBJECTIVE:The aim of our study was to evaluate the role of preoperative US, CEUS, and 99mTc-MIBI scanning with SPECT/CT in localizing diseased parathyroid glands in cases of refractory secondary hyperparathyroidism (SHPT). MATERIAL AND METHODS:Using pathological results as the gold standard, we compared the operative findings with the preoperative localization of each modality in 73 nodules and evaluated the accuracy, and sensitivity of each modality and combinations of the four modalities. RESULTS:The sensitivity of US, CEUS, 99mTc-MIBI and SPECT/CT was 98.59%, 94.37%, 50.70% and 78.87%, respectively. US had the highest sensitivity of the four imaging methods and the diagnostic sensitivity of US and CEUS was superior to that of 99mTc-MIBI (p < 0.001 and p < 0.001) and SPECT/CT (p = 0.001 and p = 0.012). In addition, we found that the sensitivity of the combination of US with CEUS, US with 99mTc-MIBI and/or SPECT/CT, CEUS with 99mTc-MIBI and/or SPECT/CT, US with CEUS and two other imaging modalities (99mTc-MIBI and/or SPECT/CT) was 98.59%, 100%, 95.77%, and 100%, respectively. CONCLUSIONS:The combination of US with SPECT/CT is the best choice for the comprehensive preoperative localization of glands in refractory SHPT. CEUS can elevate the accuracy of US in differential diagnosis via the interpretation of dynamic microvascular features.
journal_name
Clin Hemorheol Microcircjournal_title
Clinical hemorheology and microcirculationauthors
Li X,Li J,Li Y,Wang H,Yang J,Mou S,Zhou M,Jiang C,Ning Cdoi
10.3233/CH-190723subject
Has Abstractpub_date
2020-01-01 00:00:00pages
35-46issue
1eissn
1386-0291issn
1875-8622pii
CH190723journal_volume
75pub_type
杂志文章abstract：:To compare the level of endothelial nitric oxide synthase (eNOS) expression produced in heart and lung vascular tissue, the protein content was determined using Western blot analysis with the enhancement of image processing. Heart and lung extracts from 12 and 24 weeks from control (CON) and streptozotocin-induced dia...
journal_title：Clinical hemorheology and microcirculation
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abstract：:The lipoprotein lipase deficient (LPL-/-) mice and high fat-diet (HFD) induced hypertriglyceridemic mice were used to investigate the effects of cardiotonic pill (CP) on RBC rheologic abnormalities. Mice were randomly divided into the following five groups: the control group; the untreated HFD group; the untreated LPL...
journal_title：Clinical hemorheology and microcirculation
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doi：
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abstract：:Polyether ether ketone (PEEK) as a high-performance, thermoplastic implant material entered the field of medical applications due to its structural function and commercial availability. In bone tissue engineering, the combination of mesenchymal stem cells (MSCs) with PEEK implants may accelerate the bone formation and...
journal_title：Clinical hemorheology and microcirculation
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doi：10.3233/CH-152001
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abstract：:Myakuryu (MR) is a newly developed herbal medicine composing Crataegue oinnatifida bge (COB), Panax notoginseng (PN) and Ginkyo biloba (GB). To examine the effectiveness of MR, we investigated its effects on rat mesenteric microcirculatory injury induced by ischemia/reperfusion (I/R). The mesenteric microcirculation o...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:Inhalation of 100% oxygen in a hyperbaric chamber has been accepted as a useful treatment for patients with various pathologies who suffer from hypoxia. The oxidative effects of hyperbaric oxygen (HBO) on RBCs have been investigated in animals but there is not enough data on hemorheological parameters in patients foll...
journal_title：Clinical hemorheology and microcirculation
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doi：10.3233/CH-151952
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journal_title：Clinical hemorheology and microcirculation
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doi：10.3233/CH-2012-1638
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journal_title：Clinical hemorheology and microcirculation
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doi：10.3233/CH-180391
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
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journal_title：Clinical hemorheology and microcirculation
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journal_title：Clinical hemorheology and microcirculation
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journal_title：Clinical hemorheology and microcirculation
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doi：
更新日期：2006-01-01 00:00:00
abstract：:Nephelometry technique was used to register the alterations of the scattering signal from a whole blood sample due to erythrocyte aggregates in stasis and under controlled shear stress. The measured parameters were: the characteristic times of linear and three-dimensional aggregates formation, and the strength of aggr...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
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doi：10.3233/CH-2010-1326
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
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doi：10.3233/CH-2010-1307
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journal_title：Clinical hemorheology and microcirculation
pub_type： 临床试验,杂志文章
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
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journal_title：Clinical hemorheology and microcirculation
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doi：10.3233/CH-151969
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journal_title：Clinical hemorheology and microcirculation
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-151979
更新日期：2016-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
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journal_title：Clinical hemorheology and microcirculation
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1997-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
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doi：
更新日期：2006-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
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journal_title：Clinical hemorheology and microcirculation
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journal_title：Clinical hemorheology and microcirculation
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更新日期：2020-01-01 00:00:00
