Storage of aliquots of apheresis platelets for neonatal use in syringes with and without agitation.

Abstract:

BACKGROUND:To facilitate volume control in neonates, platelets (PLTs) are aliquoted and stored for short periods in non-gas-permeable syringes before infusion. Although agitation of PLTs during storage in gas-permeable bags is performed to maintain their quality, the effect of syringe agitation during storage is unknown. STUDY DESIGN AND METHODS:Double apheresis PLTs (n = 6) were collected and split, providing two identical products. On Days 2 and 4 of storage, aliquots from one bag of each pair were transferred to two syringes and stored for 6 hours on flatbed agitator or were left at 20 to 24 °C without agitation. A series of in vitro tests was performed on Days 0, 2 (Hours 0 and 6), and 4 (Hours 0 and 6). Control samples were obtained from the second matched bag that was stored on the agitator. Data were analyzed by one-way analysis of variance with differences considered significant if the p value was less than 0.05. RESULTS:Comparable results for several PLT variables were obtained with or without agitation of the syringes. On Day 4 Hour 6, pH values were 7.18 ± 0.12 (agitated syringes) and 7.19 ± 0.1 (nonagitated syringes), and extent of shape change and hypotonic shock response measurements were not significantly different between agitated syringes and nonagitated syringes (23.7 ± 6.4 and 74.3 ± 9.8% vs. 23.3 ± 5.4 and 76.0 ± 7.6%), respectively. CONCLUSION:Based on in vitro testing, apheresis PLT aliquots can be stored in syringes for at least 6 hours without agitation before transfusions.

journal_name

Transfusion

journal_title

Transfusion

authors

Diab Y,Wong E,Criss VR,Moroff G,Wagner SJ,Luban NL

doi

10.1111/j.1537-2995.2011.03230.x

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

2642-6

issue

12

eissn

0041-1132

issn

1537-2995

journal_volume

51

pub_type

临床试验,杂志文章
  • How we handled the dextran shortage: an alternative washing or dilution solution for cord blood infusions.

    abstract::Dextran 40 is the main component of the solution used to wash or dilute thawed cord blood unit (CBU) products for stem cell transplant. Dextran 40 became unavailable in the United States as of April 2014. Like many other cellular therapy laboratories in the United States, we found ourselves with limited dextran 40 inv...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13015

    authors: Reich-Slotky R,Bachegowda LS,Ancharski M,Mendeleyeva L,Rubinstein P,Rennert H,Shore T,van Besien K,Cushing M

    更新日期:2015-06-01 00:00:00

  • Anti-Cob causing acute hemolytic transfusion reaction.

    abstract::An example of anti-Cob which caused an acute hemolytic transfusion reaction is reported. Immunohematologic studies showed this antibody to be an IgG immunoglobulin that weakly bound complement and reacted in the antiglobulin phase of the crossmatch. The unit of whole blood implicated in the hemolytic transfusion react...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1982.22282177127.x

    authors: Lee EL,Bennett C

    更新日期:1982-03-01 00:00:00

  • A comprehensive program to minimize platelet outdating.

    abstract:BACKGROUND:Platelet (PLT) transfusions are essential for patients who are bleeding or have an increased risk of bleeding due to a decreased number or abnormal function of circulating PLTs. A shelf life of 5 days for PLT products presents an inventory management challenge. In 2006, greater than 10% of apheresis PLTs mad...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.03039.x

    authors: Fuller AK,Uglik KM,Braine HG,King KE

    更新日期:2011-07-01 00:00:00

  • UMC, another Cromer-related blood group antigen.

    abstract::An antibody found in the serum of a Japanese blood donor detects a new high-frequency red cell antigen named UMC. UMC is absent from Inab phenotype cells, weakly expressed on Dr(a-) cells, and destroyed by alpha-chymotrypsin but not trypsin treatment of red cells. UMC is, therefore, a Cromer-related antigen. Immunoblo...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1989.29990070184.x

    authors: Daniels GL,Okubo Y,Yamaguchi H,Seno T,Ikuta M

    更新日期:1989-11-01 00:00:00

  • Rapid estimation of the glycerol concentration of frozen-thawed red cells prepared by the agglomeration technique.

    abstract::The glycerol concentration of frozen-thawed red cells must be less than 2 percent to prevent hemolysis upon transfusion. Three methods were investigated for monitoring the glycerol concentration of frozen-thawed red cells prepared by the agglomeration technique. The supernatant osmolality and glycerol concentration we...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1983.23483276865.x

    authors: Bongiovanni MB,Hughlett MA,Wurzel HA

    更新日期:1983-07-01 00:00:00

  • Hemovigilance survey of pathogen-reduced blood components in the Warsaw Region in the 2009 to 2013 period.

    abstract:BACKGROUND:In 2009 the Mirasol Pathogen Reduction Technology (PRT) was introduced to the routine blood component production of the Regional Blood Transfusion Center in Warsaw (RBTCW). The goal of this study was to investigate the safety of Mirasol-treated blood components. STUDY DESIGN AND METHODS:The accumulated pass...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.13330

    authors: Łętowska M,Przybylska Z,Piotrowski D,Lachert E,Rosiek A,Rzymkiewicz L,Cardoso M

    更新日期:2016-03-01 00:00:00

  • Metabolic phenotypes of standard and cold-stored platelets.

    abstract:BACKGROUND:Conventional platelet (PLT) storage at room temperature under continuous agitation results in a limited shelf life (5 days) and an increased risk of bacterial contamination. However, both of these aspects can be ameliorated by cold storage. Preliminary work has suggested that PLTs can be cold stored for up t...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15651

    authors: D'Alessandro A,Thomas KA,Stefanoni D,Gamboni F,Shea SM,Reisz JA,Spinella PC

    更新日期:2020-06-01 00:00:00

  • Semaphorin 3A alters endothelial cell immunogenicity by regulating Class II transactivator activity circuits.

    abstract:BACKGROUND:Endothelial cells (ECs) play a pivotal role in the allogeneic immune response upon transplantation. Semaphorin 3A (Sema3A) was implicated in the modulation of EC growth, but its effects on immunogenicity were not previously investigated. STUDY DESIGN AND METHODS:ECs were transduced with a lentiviral vector ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12631

    authors: Schlahsa L,Zhang H,Battermann A,Verboom M,Immenschuh S,Eiz-Vesper B,Stripecke R,Engelmann K,Blasczyk R,Figueiredo C

    更新日期:2014-08-01 00:00:00

  • A tale of two ports: an in vitro comparison of flow characteristics for therapeutic plasma exchange.

    abstract::Tunneled central venous catheters with ports are increasingly used for therapeutic apheresis procedures. Vortex ports have been used as access for therapeutic apheresis procedures, but are not ideal for therapeutic plasma exchange (TPE) procedures due to lower flow rates. We performed an in vitro experiment to compare...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14494

    authors: De Simone N,Sarode R

    更新日期:2018-02-01 00:00:00

  • New HIV infections from blood transfusions averted in 28 countries supported by PEPFAR blood safety programs, 2004-2015.

    abstract:BACKGROUND:To quantify the impact of the US President's Emergency Plan for AIDS Relief (PEPFAR) on the risk of HIV transmission through infected blood donations in countries supported by PEPFAR blood safety programs. METHODS:Data reported to the World Health Organization Global Database on Blood Safety were analyzed f...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.16256

    authors: Mili FD,Teng Y,Shiraishi RW,Yu J,Bock N,Drammeh B,Watts DH,Benech I

    更新日期:2021-01-28 00:00:00

  • Preparation of granulocyte concentrates for neonatal patient transfusion.

    abstract::As an adjunct to antibiotic therapy, granulocytes for infusion often are required within hours of the diagnosis of neonatal sepsis. The logistics of obtaining granulocytes by leukapheresis were evaluated in order to provide, at short notice, a low volume, highly concentrated product. An average of 4.0 X 10(9) granuloc...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1984.24384225030.x

    authors: Kalmin ND,Liles BA

    更新日期:1984-05-01 00:00:00

  • The risk of transfusion-transmitted infections in sub-Saharan Africa.

    abstract:BACKGROUND:Blood transfusions carry the risk of transmitting infections. This risk has been studied in detail in high-income countries but not in sub-Saharan Africa. This study estimates the risks of acquiring human immunodeficiency virus (HIV), hepatitis B virus (HBV), or hepatitis C virus (HCV) from a single unit of ...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/j.1537-2995.2009.002402.x

    authors: Jayaraman S,Chalabi Z,Perel P,Guerriero C,Roberts I

    更新日期:2010-02-01 00:00:00

  • Intraoperative cell salvage in obstetrics: is it a real therapeutic option?

    abstract::Obstetric hemorrhage is a leading cause of maternal and perinatal mortality worldwide. Intraoperative blood salvage is common practice in many surgical specialties but its safety in obstetrics is questioned for concerns on the risks of contamination of recovered blood with amniotic fluid (AF) and of maternal-fetal all...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/j.1537-2995.2011.03116.x

    authors: Liumbruno GM,Liumbruno C,Rafanelli D

    更新日期:2011-10-01 00:00:00

  • Evaluation of a new polyacrolein microsphere (acrobead) protein A column: an in vitro study using the blood of patients with immune thrombocytopenia or malignancies.

    abstract::The present study describes the use of a new polyacrolein microsphere (acrobead) protein A column. This method enables immunomodulation by the perfusion of whole blood. The efficacy of the column and its adverse effects following perfusion of blood of patients with immune thrombocytopenic purpura (ITP) or malignancies...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1992.32392213802.x

    authors: Dvilansky A,Aharon M,Riesenfeld G,Nathan I

    更新日期:1992-03-01 00:00:00

  • Predonation hematocrit measurement by whole blood electrical conductivity assay.

    abstract::The whole blood electrical conductivity method for predonation hematocrit determinations was studied. Forty capillary and venous blood samples were tested concurrently with electrical conductivity and centrifugation methods. The electrical conductivity method demonstrated acceptable accuracy but was less precise than ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1985.25385219908.x

    authors: Schifman RB,Rivers SL,Delduca M

    更新日期:1985-05-01 00:00:00

  • Estimated risk of Chikungunya viremic blood donation during an epidemic on Reunion Island in the Indian Ocean, 2005 to 2007.

    abstract:BACKGROUND:Between 2005 and 2007, Chikungunya virus (CHIKV) caused a massive epidemic on Reunion Island with a major peak in the number of cases in February 2006. Blood donation was interrupted on the island in January 2006. STUDY DESIGN AND METHODS:Estimates of the mean risk of viremic blood donation on Reunion Islan...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.01646.x

    authors: Brouard C,Bernillon P,Quatresous I,Pillonel J,Assal A,De Valk H,Desenclos JC,workgroup \Quantitative Estimation of the Risk of Blood Donation Contamination by Infectious Agents\.

    更新日期:2008-07-01 00:00:00

  • Preparation of pooled cryoprecipitate for treatment of hemophilia A in a home care program.

    abstract::Cryoprecipitate is used infrequently in home therapy for patients with hemophilia A since freezer storage is required and resuspension and pooling of thawed cryoprecipitate is cumbersome. We evaluated procedures for preparation of cryoprecipitate in an "open system" so that four to six bags of cryoprecipitate could be...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1984.24685066816.x

    authors: Smith KJ,Hodges PA

    更新日期:1984-11-01 00:00:00

  • Monitoring for underutilization of RBC components and platelets.

    abstract:BACKGROUND:Monitoring blood transfusion for overutilization is standard practice at most institutions. STUDY DESIGN AND METHODS:This study monitored for underutilization of blood transfusion over a 14-month period, by evaluating patients who had Hb levels that were reported to be <5 g per dL or platelet counts <10 x 1...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41050587.x

    authors: Saxena S,Wehrli G,Makarewicz K,Sartorelli J,Shulman IA

    更新日期:2001-05-01 00:00:00

  • Duffy antigen changes on red blood cells stored at low temperature.

    abstract::Red blood cells stored in saline solution for two weeks at 12 C lose some of their Fya, Fyb, and Fy3 antigenicity. At the same time substances with specific inhibitory activity against appropriate Duffy antibodies appear in the saline. Similar changes could not be recognized in time-expired commercial reagent red bloo...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1981.21381201813.x

    authors: Williams D,Johnson CL,Marsh WL

    更新日期:1981-05-01 00:00:00

  • Adoption trends of point of issue Verax PGD rapid test for bacterial screening of platelets between 2013 and 2018 among hospitals supplied by the American Red Cross and impact on platelet availability.

    abstract:BACKGROUND:Point-of-issue tests, such as the Verax Pan Genera Detection (PGD) test, can be used to mitigate the occurrence of septic reactions. Little is known about how widespread the adoption of the PGD test is across US hospitals. STUDY DESIGN/METHODS:The Red Cross hemovigilance database was used to determine the n...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15817

    authors: Rios J,Westra J,Dy B,Young PP

    更新日期:2020-07-01 00:00:00

  • Estimating the incubation time distribution and expected number of cases of transfusion-associated acquired immune deficiency syndrome.

    abstract::The number of cases of transfusion-associated acquired immune deficiency syndrome (TA-AIDS) that will be seen over the next few years is difficult to estimate, because of the uncertainty about the number of persons infected with the human immunodeficiency virus (HIV) via blood transfusion and about the duration of the...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1989.29890020437.x

    authors: Kalbfleisch JD,Lawless JF

    更新日期:1989-10-01 00:00:00

  • Natural anti-A and anti-B of the ABO system: allo- and autoantibodies have different epitope specificity.

    abstract:BACKGROUND:According to Landsteiner's law, alloantibodies are prevalent and autoantibodies are absent in the ABO blood group system. However, one study (Spalter et al., Blood 1999;93:4418-24) has suggested that low-affinity ABO autoantibodies, mitigated by anti-idiotypic immunoglobulins are also prevalent, while anothe...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03381.x

    authors: Obukhova P,Korchagina E,Henry S,Bovin N

    更新日期:2012-04-01 00:00:00

  • Combination therapy of deferasirox and deferoxamine shows significant improvements in markers of iron overload in a patient with β-thalassemia major and severe iron burden.

    abstract:BACKGROUND:Iron overload is a common complication of patients with β-thalassemia major (TM). Despite the availability of three iron chelators, deferoxamine (DFO), deferiprone (DFP), and deferasirox (DFX), some patients fail to respond adequately to monotherapy with any of them. We report a case of TM who had refractory...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12335

    authors: Voskaridou E,Komninaka V,Karavas A,Terpos E,Akianidis V,Christoulas D

    更新日期:2014-03-01 00:00:00

  • Mitochondrial damage-associated molecular patterns as potential proinflammatory mediators in post-platelet transfusion adverse effects.

    abstract:BACKGROUND:Platelet concentrates (PCs) are the most common blood components eliciting nonhemolytic transfusion reactions (NHTRs), such as allergic transfusion reactions and febrile reactions. However, the precise mechanisms of NHTRs in PC transfusion remain largely unknown. Previous studies reported that mitochondria-d...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13535

    authors: Yasui K,Matsuyama N,Kuroishi A,Tani Y,Furuta RA,Hirayama F

    更新日期:2016-05-01 00:00:00

  • Hematology patterns after hemoglobin-based oxygen carrier resuscitation from severe controlled hemorrhage with prolonged delayed definitive care.

    abstract:BACKGROUND:The hemoglobin-based oxygen carrier (HBOC-201) resuscitation fluid improves outcome in hemorrhagic shock swine models with minimal coagulopathy. Herein, coagulation parameters were evaluated after resuscitation with HBOC-201 after severe bleeding and prolonged delay to definitive care. STUDY DESIGN AND METH...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01435.x

    authors: Arnaud F,Fasipe D,Philbin N,Rice J,Flournoy WS,Ahlers S,McCarron R,Freilich D

    更新日期:2007-11-01 00:00:00

  • Evaluation of two viral inactivation methods for the preparation of safer factor VIII and factor IX concentrates.

    abstract::We report here the results of our evaluation of two procedures to eliminate viruses in factor VIII and factor IX coagulation factor concentrates. Both procedures were equally effective in the in vitro destruction of marker viruses. However, in a controlled infectivity test in chimpanzees, treatment at 60 degrees C for...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1537-2995.1985.25686071421.x

    authors: Heldebrant CM,Gomperts ED,Kasper CK,McDougal JS,Friedman AE,Hwang DS,Muchmore E,Jordan S,Miller R,Sergis-Davenport E

    更新日期:1985-11-01 00:00:00

  • Hyperhemolysis syndrome in sickle cell disease: case report (recurrent episode) and literature review.

    abstract:BACKGROUND:Hyperhemolysis syndrome (HS) has been well described both in sickle cell disease (SCD) and non-SCD patients. The pathogenesis remains unclear. The possible mechanisms include bystander hemolysis, suppression of erythropoiesis, and destruction of red cells (RBCs) due to contact lysis via activated macrophages...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.01693.x

    authors: Win N,New H,Lee E,de la Fuente J

    更新日期:2008-06-01 00:00:00

  • Red blood cell hemolysis during blood bank storage: using national quality management data to answer basic scientific questions.

    abstract:BACKGROUND:Hemolysis of red blood cells (RBCs) during blood bank storage is the most obvious manifestation of RBC storage system failure. However, its analysis is made difficult because the largest source of interunit difference is donor specific. Availability of data from national blood systems on large numbers of RBC...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02275.x

    authors: Hess JR,Sparrow RL,van der Meer PF,Acker JP,Cardigan RA,Devine DV

    更新日期:2009-12-01 00:00:00

  • Epidemiological trends of HIV-1 infection in blood donors from Catalonia, Spain (2005-2014).

    abstract:BACKGROUND:Human immunodeficiency virus 1 (HIV-1) subtype B is predominant in Spain. However, the recent arrival of immigrant populations has increased the prevalence of non-B subtypes and circulating recombinant forms. The objective of this study was to determine the prevalence of HIV-1 subtypes and transmitted drug-r...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14195

    authors: Bes M,Piron M,Casamitjana N,Gregori J,Esteban JI,Ribera E,Quer J,Puig L,Sauleda S

    更新日期:2017-09-01 00:00:00

  • Will clinical studies elucidate the connection between the length of storage of transfused red blood cells and clinical outcomes? An analysis based on the simulation of randomized controlled trials.

    abstract:BACKGROUND:The temporal pattern of the biologic mechanism linking red blood cell (RBC) storage duration with clinical outcomes is yet unknown. This study investigates how such a temporal pattern can affect the power of randomized controlled trials (RCT) to detect a relevant clinical outcome mediated by the transfusion ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03656.x

    authors: Pereira A

    更新日期:2013-01-01 00:00:00