Abstract:
:A few international pneumococcal clones dominate the population of antibiotic-resistant pneumococci. Despite the scientific paradigm that a loss in fitness is the price for acquisition of resistance, these clones spread successfully. One hundred fifty-four isolates from adult patients with community-acquired pneumonia (CAP) were analyzed. Thirty percent showed a close relationship to international clones and had fitness equal to or exceeding that of other strains (P = 0.015); these factors may result in the endurance of these strains despite a reduction of antibiotic usage.
journal_name
Antimicrob Agents Chemotherjournal_title
Antimicrobial agents and chemotherapyauthors
Rudolf D,Michaylov N,van der Linden M,Hoy L,Klugman KP,Welte T,Pletz MW,CAPNETZ Study Group.doi
10.1128/AAC.00250-11subject
Has Abstractpub_date
2011-10-01 00:00:00pages
4915-7issue
10eissn
0066-4804issn
1098-6596pii
AAC.00250-11journal_volume
55pub_type
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