Prospective comparison of transient elastography, point shear wave elastography, APRI and FIB-4 for staging liver fibrosis in chronic viral hepatitis.

abstract：:The potential interaction between chronic hepatitis B (CHB) and nonalcoholic fatty liver disease (NAFLD), two of the most prevalent liver diseases worldwide, has not been well defined. We performed liver stiffness (LS) and controlled attenuation parameter (CAP) measurements using transient elastography in 1202 CHB pat...

journal_title：Journal of viral hepatitis

authors： Hui RWH,Seto WK,Cheung KS,Mak LY,Liu KSH,Fung J,Wong DK,Lai CL,Yuen MF

更新日期：2018-01-01 00:00:00

abstract：:Hepatitis C is a complex disease and a significant public health problem. The long-term outcome of HCV infection is difficult to predict, as the virus may be eliminated or may persist to establish a chronic infection. Further investigation is required to clarify factors that determine or influence the outcome of infec...

journal_title：Journal of viral hepatitis

authors： McKiernan S,Kelleher D

更新日期：2000-05-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common complication of HCV infection leading to liver transplantation. We evaluated the impact of aetiology of liver disease on patient and graft survival following liver transplantation for HCC. From the Scientific Registry of Transplant Recipients (2002-2011), all adults wh...

journal_title：Journal of viral hepatitis

authors： Younossi ZM,Stepanova M,Saab S,Ahmed A,Lam B,Srishord M,Venkatesan C,Wai H,Henry L

更新日期：2016-01-01 00:00:00

abstract：:Patients with biopsy-proven chronic hepatitis C, who failed to respond to a previous course of either recombinant (rIFN-alpha) or lymphoblastoid (Ly IFN-alpha) interferon-alpha, were randomized to receive either leucocyte (Le) IFN-alpha (patients) or a second course of the same IFN-alpha (controls), to compare the eff...

journal_title：Journal of viral hepatitis

authors： Gaeta GB,Di Virgilio D,Russo G,Stornaiuolo G,Nicolella U,Colella F,Grimaldi M,Pasquale G,Giusti G

更新日期：1997-05-01 00:00:00

abstract：:The role of hepatitis C virus (HCV) heterogeneity in the severity of chronic hepatitis C infection remains unclear. Our aim was to study the hypervariable region 1 (HVR1) heterogeneity in patients with chronic hepatitis C infected with genotype 1b or 3 and with normal or abnormal alanine aminotransferase (ALT). HVR1 q...

journal_title：Journal of viral hepatitis

authors： Asselah T,Martinot M,Cazals-Hatem D,Boyer N,Auperin A,Le Breton V,Erlinger S,Degott C,Valla D,Marcellin P

更新日期：2002-01-01 00:00:00

abstract：SUMMARY:A simian hepatitis A virus (HAV) was identified retrospectively in a faecal sample from a rhesus monkey in India, inoculated in 1995 with a faecal suspension from a suspected patient of non-A to E hepatitis. The monkey was in captivity for 2 years in one of the experimental primate facilities in western India b...

journal_title：Journal of viral hepatitis

authors： Arankalle VA,Ramakrishnan J

更新日期：2009-03-01 00:00:00

abstract：:Better convenience and tolerability and sustained therapeutic concentrations might improve interferon (IFN) treatment for chronic hepatitis C virus (HCV) infection. In an open-label, randomized study, controlled release free (chemically unmodified) recombinant human IFN-α(2b) in poly(ether-ester) microspheres (CR-rhIF...

journal_title：Journal of viral hepatitis

authors： Dzyublyk I,Yegorova T,Moroz L,Popovych O,Zaytsev I,Miroshnichenko V,Kromminga A,Wilkes MM,van Hoogdalem EJ,Humphries JE

更新日期：2011-04-01 00:00:00

abstract：:It is unclear whether the achievement of virologic response modifies the risk of hepatocellular carcinoma (HCC) differently in chronic hepatitis B (CHB) and chronic hepatitis C (CHC). Our aim was to compare the risk of HCC between patients with CHB and CHC who achieved virological response. We analysed data from patie...

journal_title：Journal of viral hepatitis

authors： Kim GA,Han S,Kim HD,An J,Lim YS

更新日期：2017-11-01 00:00:00

abstract：AIM:Elevated body mass index (BMI) in chronic hepatitis C (CHC) has been associated with reduced rates of sustained virological response (SVR). The aims of this study were to determine whether early viral kinetics (and subsequently SVR) are influenced by weight or BMI by measuring HCV RNA at week 4 using two PCR assays...

journal_title：Journal of viral hepatitis

authors： Pattullo V,Ravindran NC,Mazzulli T,Wong DK,Heathcote EJ

更新日期：2010-12-01 00:00:00

abstract：:A large number of studies have reported on spontaneous viral clearance rates in acute hepatitis C infection, however most have been small, and reported rates have varied quite widely. To improve the precision of the estimated rate of spontaneous viral clearance, a systematic review was conducted of longitudinal studie...

journal_title：Journal of viral hepatitis

authors： Micallef JM,Kaldor JM,Dore GJ

更新日期：2006-01-01 00:00:00

abstract：:Hepatitis C (HCV) infection can cause cirrhosis, liver cancer and death in the absence of treatment. Many people living in the UK but born overseas are believed to be infected with HCV although many are unlikely to know they are infected. The aim of this study is to assess the potential for a case-finding approach to ...

journal_title：Journal of viral hepatitis

authors： Miners AH,Martin NK,Ghosh A,Hickman M,Vickerman P

更新日期：2014-01-01 00:00:00

abstract：:Patients with chronic hepatitis B (HBsAg-positive) are at risk of viral reactivation if rituximab is administered without antiviral treatment, a potentially fatal complication of treatment. Patients with so-called 'resolved hepatitis B virus infection' (HBsAg-negative/cAb-positive) may also be at risk. We performed a ...

journal_title：Journal of viral hepatitis

authors： Mozessohn L,Chan KK,Feld JJ,Hicks LK

更新日期：2015-10-01 00:00:00

abstract：:Improved understanding of natural history of hepatitis C virus (HCV) RNA levels in chronic infection provides enhanced insights into immunopathogenesis of HCV and has implications for the clinical management of chronic HCV infection. This study assessed factors associated with HCV RNA levels during early chronic infec...

journal_title：Journal of viral hepatitis

authors： Hajarizadeh B,Grady B,Page K,Kim AY,McGovern BH,Cox AL,Rice TM,Sacks-Davis R,Bruneau J,Morris M,Amin J,Schinkel J,Applegate T,Maher L,Hellard M,Lloyd AR,Prins M,Geskus RB,Dore GJ,Grebely J,InC3 Study Group.

更新日期：2015-09-01 00:00:00

abstract：:To assess the impact of sequential therapy with adefovir dipivoxil (ADV) and pegylated interferon alfa-2a (PEG-IFN) on virological (serum HBV-DNA) and serological (serum HBsAg) response in 20 consecutive HBeAg-negative patients. Patients received ADV for 20 weeks, then ADV and PEG-IFN for 4 weeks and lastly PEG-IFN fo...

journal_title：Journal of viral hepatitis

authors： Moucari R,Boyer N,Ripault MP,Castelnau C,Mackiewicz V,Dauvergne A,Valla D,Vidaud M,Chanoine MH,Marcellin P

更新日期：2011-08-01 00:00:00

abstract：:A significant proportion of chronic hepatitis C patients fails to achieve sustained virologic response even after treatment with the current, more potent, combination of pegylated interferon-alpha (IFNa) plus ribavirin. Such patients represent a rather heterogeneous group and may be divided initially into relapsers an...

journal_title：Journal of viral hepatitis

authors： Papatheodoridis GV,Cholongitas E

更新日期：2004-07-01 00:00:00

abstract：:Morbidity and mortality attributable to chronic hepatitis C virus (HCV) infection are increasing in many countries as the infected population ages. Models were developed for 15 countries to quantify and characterize the viremic population, as well as estimate the number of new infections and HCV related deaths from 20...

journal_title：Journal of viral hepatitis

authors： Hatzakis A,Chulanov V,Gadano AC,Bergin C,Ben-Ari Z,Mossong J,Schréter I,Baatarkhuu O,Acharya S,Aho I,Anand AC,Andersson MI,Arendt V,Arkkila P,Barclay K,Bessone F,Blach S,Blokhina N,Brunton CR,Choudhuri G,Cisneros

更新日期：2015-01-01 00:00:00

abstract：:Hepatitis A incidence has declined in most countries through a combination of prevention measures, augmented through the use of a highly effective vaccine. In Australia, the proportion of the population susceptible to hepatitis A infection has declined over time due to high rates of opportunistic vaccination as well a...

journal_title：Journal of viral hepatitis

authors： Jayasundara D,Hui BB,Regan DG,Heywood AE,MacIntyre CR,Wood JG

更新日期：2019-01-01 00:00:00

abstract：:Extremely low levels of serum hepatitis C virus (HCV) RNA can be detected by COBAS TaqMan HCV test. To investigate whether the COBAS TaqMan HCV test is useful for measuring rapid virological response (RVR) and early virological response (EVR) to predict sustained virological response (SVR), we compared the virological...

journal_title：Journal of viral hepatitis

authors： Kanda T,Imazeki F,Yonemitsu Y,Mikami S,Takada N,Nishino T,Takashi M,Tsubota A,Kato K,Sugiura N,Tawada A,Wu S,Tanaka T,Nakamoto S,Mikata R,Tada M,Chiba T,Kurihara T,Arai M,Fujiwara K,Kanai F,Yokosuka O

更新日期：2011-07-01 00:00:00

abstract：:Children with chronic hepatitis C may be ideal candidates for treatment with interferon alpha (IFNalpha) as they have liver disease at an early stage. However, adverse drug reactions need to be considered. The aim of this study was to conduct a systematic review of literature on interferon therapy of chronic hepatitis...

journal_title：Journal of viral hepatitis

authors： Di Ciommo V,Russo P,Ravà L,Caprino L

更新日期：2003-05-01 00:00:00

abstract：:Transcription of p21 was activated in hepatitis C virus (HCV) Core-expressing HepG2 cells where its upstream p53 was stabilized. However, this effect was not absolutely required for the activation of p21 by Core, as demonstrated in Hep3B cells. In addition, an opposite effect on the transcription of p21 was observed i...

journal_title：Journal of viral hepatitis

authors： Kwun HJ,Jang KL

更新日期：2003-07-01 00:00:00

abstract：:The use of tenofovir disoproxil fumarate (TDF) is associated with a risk of renal dysfunction. We investigated whether TDF is associated with the deterioration of renal function in patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) requiring frequent computed tomography (CT) evaluations and t...

journal_title：Journal of viral hepatitis

authors： Jeon MY,Lee JS,Lee HW,Kim BK,Park JY,Kim DY,Han KH,Ahn SH,Kim SU

更新日期：2020-09-01 00:00:00

abstract：:Peginterferon alpha-2a (40 kDa) plus ribavirin is effective at achieving sustained viral response compared with no treatment in patients with chronic hepatitis C (CHC) and persistently normal aminotransferase levels (PNALT). The cost-effectiveness of treating CHC in the setting of PNALT has not been assessed. Disease ...

journal_title：Journal of viral hepatitis

authors： Hornberger J,Farci P,Prati D,Zeuzem S,Green J,Patel KK

更新日期：2006-06-01 00:00:00

abstract：:Women with chronic hepatitis B should maintain nucleotide analogue treatment to prevent disease progression during pregnancy. The aim of this study was to prospectively evaluate the efficacy and safety of telbivudine used throughout pregnancy for preventing hepatitis B virus (HBV) mother-to-child transmission (MTCT). ...

journal_title：Journal of viral hepatitis

authors： Yi W,Li MH,Xie Y,Wu J,Hu YH,Zhang D,Zhang Y,Cao WH

更新日期：2017-11-01 00:00:00

abstract：:Primary or secondary failure of adefovir dipivoxil (ADV) therapy of chronic hepatitis B is not infrequent. The reasons for suboptimal responses are not well defined. In HIV and hepatitis C virus infection, failure of antiviral drug therapy has been linked with low blood drug levels. We have studied 20 well-defined pat...

journal_title：Journal of viral hepatitis

authors： Deterding K,Naesens L,Buti M,Janssen H,Kirschner J,Guerrero A,Reijnders J,Neyts J,Zoulim F,Wedemeyer H

更新日期：2011-07-01 00:00:00

abstract：:Favourable efficacy and safety profiles for simeprevir in combination with pegylated interferon alpha (PEG-IFNα) and ribavirin (triple therapy) have been shown in clinical trials. This study was carried out to evaluate the effectiveness of simeprevir-based triple therapy for patients with prior telaprevir treatment fa...

journal_title：Journal of viral hepatitis

authors： Ogawa E,Furusyo N,Dohmen K,Kajiwara E,Kawano A,Nomura H,Takahashi K,Satoh T,Azuma K,Nakamuta M,Koyanagi T,Kotoh K,Shimoda S,Hayashi J,Kyushu University Liver Disease Study (KULDS) Group.

更新日期：2015-12-01 00:00:00

abstract：:An estimated incidence of hepatocellular carcinoma (HCC) in Mongolia is currently one of the highest in the world. According to previous reports, the sero-prevalence of hepatitis B (HBV) and hepatitis C (HCV) viruses in general population of the country is very high (HBV, 10% and HCV, 15%, respectively). Moreover, the...

journal_title：Journal of viral hepatitis

authors： Kurbanov F,Tanaka Y,Elkady A,Oyunsuren T,Mizokami M

更新日期：2007-09-01 00:00:00

abstract：:DNA-based vaccination appears of promise for chronic hepatitis B immunotherapy, although there is an urgent need to increase its efficacy. In this preclinical study, we evaluated the therapeutic benefit of cytokine (IL-2, IFN-γ) genes co-delivery with DNA vaccine targeting hepadnaviral proteins in the chronic duck hep...

journal_title：Journal of viral hepatitis

authors： Saade F,Buronfosse T,Guerret S,Pradat P,Chevallier M,Zoulim F,Jamard C,Cova L

更新日期：2013-04-01 00:00:00

abstract：:In 1996, a combined vaccine against both hepatitis A and B was licensed and commercialized and has been recommended for healthcare personnel in Belgium. This study compares the immunogenicity against hepatitis B virus (HBV) and safety of two vaccination schedules (0-1-12 months and 0-1-6 months) with this vaccine. Thi...

journal_title：Journal of viral hepatitis

authors： De Schryver A,Verstrepen K,Vandersmissen L,Vandermeeren N,Vernaillen I,Vranckx R,Van Damme P,van Sprundel M

更新日期：2011-04-01 00:00:00

abstract：:Testing and linkage to care are important determinants of hepatitis C virus (HCV) treatment effectiveness. Public health clinics serve populations at high risk of HCV. We investigated their potential to serve as sites for HCV testing, initiation of and linkage to HCV care. Cross-sectional study of patients accessing s...

journal_title：Journal of viral hepatitis

authors： Falade-Nwulia O,Mehta SH,Lasola J,Latkin C,Niculescu A,O'Connor C,Chaulk P,Ghanem K,Page KR,Sulkowski MS,Thomas DL

更新日期：2016-05-01 00:00:00

abstract：:Better understanding of hepatitis B virus (HBV) replication, natural history and the immunopathogenesis of chronic hepatitis B, together with the introduction of effective agents with different mechanisms of action are the basis for better therapeutic strategies against chronic hepatitis B. Among currently available d...

journal_title：Journal of viral hepatitis

authors： Liaw YF

更新日期：2002-11-01 00:00:00