Effects of the polysaccharide chain of lipopolysaccharide in an experimental massive hepatic cell necrosis model.

abstract：:The fibroblast growth factors (FGFs) play important roles in morphogenesis, angiogenesis, tissue remodeling, and carcinogenesis. Human FGF-20 has been cloned and characterized in this study. FGF-20 encodes a 211-amino-acid polypeptide with the FGF-core domain. A strong hydrophobic region was found in the FGF-core doma...

journal_title：Biochemical and biophysical research communications

authors： Kirikoshi H,Sagara N,Saitoh T,Tanaka K,Sekihara H,Shiokawa K,Katoh M

更新日期：2000-08-02 00:00:00

abstract：:In a recent publication [Biochem. Biophys. Res. Commun. 317 (2004) 957] it was proposed that the 'effective number of codons' (Nc) in a gene should be calculated by summing the individual amino acid Nc's using rounding whenever the codon homozygosities are lower than the reciprocal value of the number of members of th...

journal_title：Biochemical and biophysical research communications

authors： Fuglsang A

更新日期：2005-02-04 00:00:00

abstract：:One physiological function proposed for RNA interference (RNAi) is to constrain expression of repetitive elements and thereby reduce the incidence of retrotransposition. Consistent with this model is that inhibiting the RNAi pathway results in an increase in expression of repetitive elements in preimplantation mouse e...

journal_title：Biochemical and biophysical research communications

authors： Puschendorf M,Stein P,Oakeley EJ,Schultz RM,Peters AH,Svoboda P

更新日期：2006-08-18 00:00:00

abstract：:Emp, originally detected in erythroblastic islands, is expressed in numerous cell types and tissues suggesting a functionality not limited to hematopoiesis. To study the function of Emp in non-hematopoietic cells, an epitope-tagged recombinant human Emp was expressed in HEK cells. Preliminary studies revealed that Emp...

journal_title：Biochemical and biophysical research communications

authors： Bala S,Kumar A,Soni S,Sinha S,Hanspal M

更新日期：2006-04-21 00:00:00

abstract：:Platelet activating factor was isolated from the lesional scale of psoriatic patients using the method described by Bligh and Dyer (8). The extract was subjected to thin layer chromatography, and the region of the plate co-migrating with platelet activating factor removed. A portion of each sample was assayed for aggr...

journal_title：Biochemical and biophysical research communications

authors： Mallet AI,Cunningham FM

更新日期：1985-01-16 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Biochemical and biophysical research communications

authors： Xiao F,Hu Q,Zeng M,Guan L,Liu X,Yang Y,Zhong C

更新日期：2012-04-13 00:00:00

abstract：:Eight amino acid permease genes from the protozoan parasite Leishmania donovani (AAPLDs) were cloned, sequenced, and shown to be expressed in promastigotes. Seven of these belong to the amino acid transporter-1 and one to the amino acid polyamino-choline superfamilies. Using these sequences as well as known and charac...

journal_title：Biochemical and biophysical research communications

authors： Akerman M,Shaked-Mishan P,Mazareb S,Volpin H,Zilberstein D

更新日期：2004-12-03 00:00:00

abstract：:Autophagy is a bulk degradation process for subcellular proteins and organelles to manage cell starvation. Autophagy is associated with the formation of autophagosomes and further functions as a defense mechanism against infection by various pathogens. Human papillomavirus (HPV) infection induces an autophagy response...

journal_title：Biochemical and biophysical research communications

authors： Ishii Y

更新日期：2013-04-19 00:00:00

abstract：:Nitric oxide (NO) produced by macrophages plays an important role in host defense and inflammation. We found that two agrochemicals, alachlor and carbaryl, inhibit lipopolysaccharide (LPS)-induced NO production by macrophages. In the present study, we investigated this inhibitory mechanism in RAW 264 cells. Both chemi...

journal_title：Biochemical and biophysical research communications

authors： Shimomura-Shimizu M,Sugiyama K,Muroi M,Tanamoto K

更新日期：2005-07-08 00:00:00

abstract：:Signalling through the chemokine stromal derived factor (SDF)-1alpha and its receptor CXCR4 has been recognized as a key event in the migratory response of hematopoietic stem and progenitor cells (HPC). Small GTPases of the Rho/Rac family might be involved in SDF-1alpha signalling at several different levels. In the p...

journal_title：Biochemical and biophysical research communications

authors： Henschler R,Piiper A,Bistrian R,Möbest D

更新日期：2003-11-28 00:00:00

abstract：:Serum prealbumin isolated from a Japanese patient with familial amyloidotic polyneuropathy (FAP) has been found to consist of a mixture of normal prealbumin and a prealbumin variant which contains a methionine for valine substitution at position 30. The prealbumin variant in the serum is identical to the prealbumin va...

journal_title：Biochemical and biophysical research communications

authors： Nakazato M,Kangawa K,Minamino N,Tawara S,Matsuo H,Araki S

更新日期：1984-07-31 00:00:00

abstract：:VDR regulates gene expression in a ligand-dependent way by binding to cognate enhancer elements of target gene promoters. The ligand-dependent activation function, AF-2, of VDR is thought to require transcriptional co-activators/co-repressors together with basal transcriptional machinery. Using a yeast two hybrid syst...

journal_title：Biochemical and biophysical research communications

authors： Imai T,Matsuda K,Shimojima T,Hashimoto T,Masuhiro Y,Kitamoto T,Sugita A,Suzuki K,Matsumoto H,Masushige S,Nogi Y,Muramatsu M,Handa H,Kato S

更新日期：1997-04-28 00:00:00

abstract：:In this report, we describe the expression and function of human Sp5, a member of the Sp family of zinc finger transcription factors. Like other family members, the Sp5 protein contains a Cys2His2 zinc finger DNA binding domain at the C-terminus. Our experiments employing Gal4-Sp5 fusion proteins reveal multiple trans...

journal_title：Biochemical and biophysical research communications

authors： Chen Y,Guo Y,Ge X,Itoh H,Watanabe A,Fujiwara T,Kodama T,Aburatani H

更新日期：2006-02-17 00:00:00

abstract：:FLASH is a huge multifunctional nuclear protein that has been linked to apoptotic signalling, transcriptional control and Cajal body function. To gain further insight into the functions of the FLASH protein, we performed a yeast two-hybrid screening with FLASH as bait and identified the SUMO-conjugating enzyme Ubc9 as...

journal_title：Biochemical and biophysical research communications

authors： Alm-Kristiansen AH,Norman IL,Matre V,Gabrielsen OS

更新日期：2009-09-25 00:00:00

abstract：:Human Protein tyrosine kinase 6 (PTK6)(EC:2.7.10.2), also known as the breast tumor kinase (BRK), is an intracellular non-receptor Src-related tyrosine kinase expressed five-fold or more in human breast tumors and breast cancer cell lines but its expression being low or completely absent from normal mammary gland. The...

journal_title：Biochemical and biophysical research communications

authors： Thakur MK,Birudukota S,Swaminathan S,Battula SK,Vadivelu S,Tyagi R,Gosu R

更新日期：2017-01-22 00:00:00

abstract：:An enzyme-linked immunosorbent assay of nucleic acid sequence-based amplification (NASBA-ELISA) was developed for molecular detection of Mycobacterium tuberculosis. The primers targeting 16S rRNA were used for the amplification of bacterial RNA by the isothermal digoxigenin (DIG)-labeling NASBA process, resulting in t...

journal_title：Biochemical and biophysical research communications

authors： Gill P,Ramezani R,Amiri MV,Ghaemi A,Hashempour T,Eshraghi N,Ghalami M,Tehrani HA

更新日期：2006-09-08 00:00:00

abstract：:15-Deoxy-prostaglandin J(2)(15d-PGJ(2)) is an endogenous ligand of peroxisome proliferator-activated receptor gamma (PPARgamma) and plays an important role in the regulation of endothelial cell growth and apoptosis. However, the detailed mechanisms are poorly understood. We hypothesized that 15d-PGJ(2) might affect PD...

journal_title：Biochemical and biophysical research communications

authors： Zhang J,Fu M,Zhao L,Chen YE

更新日期：2002-10-18 00:00:00

abstract：:Microglia, brain macrophages, are thought to be the primary target of HIV-1 infection in the brain, because they exclusively express the CD4 antigen which is effectively used for viral entry. The expression of CD4 mRNA in cultured microglia could be detected by the reverse-PCR method. Using this and immunohistochemica...

journal_title：Biochemical and biophysical research communications

authors： Sawada M,Suzumura A,Marunouchi T

更新日期：1992-12-15 00:00:00

abstract：:During the course of investigations on the catabolism of acetylpolyamines by microorganisms, we found that acetylpolyamine amidohydrolase was produced by Mycoplana bullata FERM BP-1845 and isolated the enzyme from the cell-free extract in crystalline form. The enzyme had an apparent molecular weight of 67 kDa and was ...

journal_title：Biochemical and biophysical research communications

authors： Fujishiro K,Ando M,Uwajima T

更新日期：1988-12-30 00:00:00

abstract：:Gastrin heptadecapeptides (gastrins I and II which differ in the presence of sulfate on the tyrosine of the latter) have been purified and sequenced from several mammalian species including pig, dog, cat, sheep, cow, human and rat. A 34 amino acid precursor ("big" gastrin), generally accounting for only 5% of total ga...

journal_title：Biochemical and biophysical research communications

authors： Shinomura Y,Eng J,Yalow RS

更新日期：1987-02-27 00:00:00

abstract：:The Tat protein from HIV-1 fused with heterologous proteins traverses biological membranes in a transcellular process called: protein transduction. This has already been successfully exploited in various biological models, but never in the nematode worm Caenorhabditis elegans. TAT-eGFP or GST-eGFP proteins were fed to...

journal_title：Biochemical and biophysical research communications

authors： Delom F,Fessart D,Caruso ME,Chevet E

更新日期：2007-01-19 00:00:00

abstract：:Binding sites for inositol trisphosphate (IP3) have been identified in bovine adrenal cortex, employing [32P]IP3 prepared from human erythrocytes radiolabeled with [32P]ATP. IP3 was bound to adrenal microsomes with high affinity (Kd = 5 nM) and low capacity (186 fmol/mg protein). During kinetic studies, half-maximal b...

journal_title：Biochemical and biophysical research communications

authors： Baukal AJ,Guillemette G,Rubin R,Spät A,Catt KJ

更新日期：1985-12-17 00:00:00

abstract：:Nanosecond and steady fluorescence techniques have been employed to study the interaction of retinol with protein disulfide isomerase (PDI). Retinol binds tightly to PDI; and the rotational correlation time (θ = 36 ns) corresponds to a monomeric subunit of 55 kDa. The enzyme does not undergo aggregation in the p...

journal_title：Biochemical and biophysical research communications

authors： Churchich JE

更新日期：1999-07-22 00:00:00

abstract：:A 5T/6T polymorphism in the human MMP-3 promoter affects gene expression and impacts the risk and/or severity of various pathological conditions. Chromatin immunoprecipitation (ChIP) in human fibroblasts homozygous for the 6T site demonstrate that it is bound by NF-kappaB and ZBP-89 transcription factors in its native...

journal_title：Biochemical and biophysical research communications

authors： Borghaei RC,Gorski G,Javadi M,Mariah Chambers.

更新日期：2009-05-01 00:00:00

abstract：:The eukaryotic DNA cytosine-5-methyltransferase (E.C.2.1.1.37) is known to methylate cytosine in DNA mainly, but not exclusively in C-G. In the present study the minor, non-C-G recognition sequences of a rat DNA methyltransferase were analyzed by Maxam-Gilbert sequencing of in vitro methylated SV40 DNA. The enzyme met...

journal_title：Biochemical and biophysical research communications

authors： Hubrich-Kühner K,Buhk HJ,Wagner H,Kröger H,Simon D

更新日期：1989-05-15 00:00:00

abstract：:The effect of endothelin (ET) on the cytosolic-free calcium [(Ca2+]i) changes in polymorphonuclear leukocytes (PMN) from normal humans and Wistar rats was investigated. ET induced a dose-related [Ca2+]i peak. This [Ca2+]i transient was blunted by TMB-8 (10(-5)M) and by Ca(2+)-free EGTA medium, therefore suggesting a r...

journal_title：Biochemical and biophysical research communications

authors： Lopez Farre A,Riesco A,Moliz M,Egido J,Casado S,Hernando L,Caramelo C

更新日期：1991-08-15 00:00:00

abstract：:The diastereomeric GSH derivatives gamma-L-Glu-L-allo-thioThr-Gly (6) and gamma-L-Glu-L-thioThr-Gly (6a) have been synthesized as specific probes of the steric environment near the cysteinyl residue of enzyme bound glutathionyl substrates. Experiments with glyoxalase I indicate that while 6a-methylglyoxal thiohemiacet...

journal_title：Biochemical and biophysical research communications

authors： Xie XF,Creighton DJ

更新日期：1991-05-31 00:00:00

abstract：:Vaspin, an adipocytokine recently identified in a rat model of type 2 diabetes, has been suggested to have an insulin-sensitizing effect. However, the exact mechanism underlying this action has not been fully elucidated. Furthermore, the specific function of vaspin is largely unknown, especially in vascular cells. We ...

journal_title：Biochemical and biophysical research communications

authors： Jung CH,Lee WJ,Hwang JY,Seol SM,Kim YM,Lee YL,Park JY

更新日期：2011-09-23 00:00:00

abstract：:The PAX3 transcription factor is the key regulator of melanocyte development during embryogenesis and is also frequently found in melanoma cells. While PAX3 is known to regulate melanocyte differentiation, survival, proliferation and migration during development, it is not clear if its function is maintained in adult ...

journal_title：Biochemical and biophysical research communications

authors： Medic S,Rizos H,Ziman M

更新日期：2011-08-12 00:00:00

abstract：:A series of novel, azacyclic ureas which are highly potent inhibitors of the HIV-1 protease (IC50 = 4.1 to < 0.5 nM) were synthesized. Aqueous solubilities of this series of compounds were improved by incorporating polar functional groups at the P1' P2 and P2' positions. These compounds also possess good anti-viral ac...

journal_title：Biochemical and biophysical research communications

authors： Sham HL,Zhao C,Marsh KC,Betebenner DA,Lin S,Rosenbrook W Jr,Herrin T,Li L,Madigan D,Vasavanonda S,Molla A,Saldivar A,McDonald E,Wideburg NE,Kempf D,Norbeck DW,Plattner JJ

更新日期：1996-08-14 00:00:00