Conceiving wholeness: women, motherhood, and ovarian transplantation, 1902 and 2004.

abstract：:The recent death of a normal healthy volunteer, as well as the increased use of normal volunteers as research subjects, has heightened the attention given to the participation of normal volunteers in clinical research. An overlooked sub-population of normal healthy volunteers are repeat, veteran volunteers. This essay...

journal_title：Perspectives in biology and medicine

authors： Tishler CL,Bartholomae S

更新日期：2003-10-01 00:00:00

abstract：:Human beings rely on metaphor as a primary cognitive device for interpreting the world around them. Metaphors figure especially strongly in discourse around health, illness, and medicine. It is not just that patients use metaphors to describe their personal experience of being unwell, or that medical professionals emp...

journal_title：Perspectives in biology and medicine

authors： Hanne M

更新日期：2015-01-01 00:00:00

abstract：:In this essay we link the rationale for the medical humanities with radical hermeneutics, a move that infuses the medical humanities with incredulity and suspicion. This orientation is particularly important at this historical moment, when the evidence-based and competency blanket is threatening to overpower all aspec...

journal_title：Perspectives in biology and medicine

authors： Wear D,Aultman JM

更新日期：2007-07-01 00:00:00

abstract：:How will developments in genetic knowledge affect the classification of disease? Leaders in genetics have suggested that knowledge of the role of genes in disease can determine nosology. Diseases might be defined by genotype, thus avoiding the limitations of more empirical approaches to categorization. Other commentat...

journal_title：Perspectives in biology and medicine

authors： Miller FA,Begbie ME,Giacomini M,Ahern C,Harvey EA

更新日期：2006-01-01 00:00:00

abstract：:Autobiographical narratives of illness and disability are influential in popular and medical discourses of illness and disability, in part because these narratives represent illness and disability within a sociocultural context, intersecting with other categories of difference. Clinicians can benefit patients through ...

journal_title：Perspectives in biology and medicine

authors： Garden R

更新日期：2010-01-01 00:00:00

abstract：:Mary Shelley's Frankenstein is 200 years old and remains relevant to 21st-century scientific experimentation. Molecular biologists today have become especially bold in their attempts to cure diseases while remaining mindful of the real dangers of their research. Scientists presumably share an abiding concern about pro...

journal_title：Perspectives in biology and medicine

authors： Nowlin C

更新日期：2018-01-01 00:00:00

abstract：:Laura Ferguson's The Visible Skeleton Series constitutes an artistic self-representation of scoliosis. Ferguson employs high-tech medical imaging and innovative graphical techniques to suggest a novel view of her skeletal "deformity." This section presents introductions to the series by a historian of medicine and by ...

journal_title：Perspectives in biology and medicine

authors： Dreger AD,Ferguson L,Aspinall C,Polly DW Jr,Beckwith JB

更新日期：2004-04-01 00:00:00

abstract：:The treatment of broken bones has long adhered to principles of tight juxtaposition of fracture ends and of strict rest. Splinting and casting with plaster of Paris helped considerably. Attempts at internal splinting with pegs, bolts, or stabilizing contraptions usually failed. Foreign materials were either not biocom...

journal_title：Perspectives in biology and medicine

authors： Pierach CA

更新日期：2014-07-01 00:00:00

abstract：:There is a need in our society to raise the national consciousness about aging, health, and the prospects for longevity, so that many more persons take responsibility for their personal health and understand what we will need in an era of health-care reform to promote health across the life course. We address this imp...

journal_title：Perspectives in biology and medicine

authors： Hamerman D,Fried LP

更新日期：2013-04-01 00:00:00

abstract：:This paper reexamines the recent case of the conjoined twins from Malta. Survival was said to be possible only through separation, which would actually leave only one twin alive. The parents refused to allow the killing of one to save the other, but the court ruled that this would amount to the neglect of innocent lif...

journal_title：Perspectives in biology and medicine

authors： Barilan YM

更新日期：2002-10-01 00:00:00

abstract：:The organism, like the molecule, the cell, and the species, is one of the fundamental levels in our hierarchical classification of life and its components. The units ranked at these levels, being concrete, particular things, are individuals in the broadest philosophical sense. But in a much narrower and more familiar ...

journal_title：Perspectives in biology and medicine

authors： Ghiselin MT

更新日期：2011-04-01 00:00:00

abstract：:C. Wright Mills said that when done well, sociology illuminates the intersection of biography and history. This essay examines how the author's vocational choices and career path were shaped by historical circumstance, leading him to a degree in sociology and to participation in the odd and interesting interdiscipline...

journal_title：Perspectives in biology and medicine

authors： De Vries R

更新日期：2017-01-01 00:00:00

abstract：:An intersex condition is one in which an individual is born with atypical male or female external genitalia, gonads, hormones, or chromosomes. Older terms, such as pseudohermaphroditism and hermaphroditism, are controversial, leading the Lawson Wilkins Pediatric Endocrine Society (LWPES) and the European Society for P...

journal_title：Perspectives in biology and medicine

authors： Reis E,McCarthy MW

更新日期：2016-01-01 00:00:00

abstract：:Although the practice of medicine continually changes in response to new biomedical understanding, novel technologies, and evolving cultural contexts, the ethical foundations of the clinical relationship between patient and physician paradoxically remain constant. There are fundamental characteristics with respect to ...

journal_title：Perspectives in biology and medicine

authors： Fuks A,Brawer J,Boudreau JD

更新日期：2012-01-01 00:00:00

abstract：:Antibody-dependent enhancement is a general in vitro property of enveloped viruses. In certain circumstances, antibody-dependent enhancement is a bona fide pathophysiologic mechanism in vivo. There are several examples of virus disease of humans and animals in which incomplete or partial immunity can lead to enhanced ...

journal_title：Perspectives in biology and medicine

authors： Burke DS

更新日期：1992-07-01 00:00:00

abstract：:Popular fiction responds to, and may exacerbate, public anxieties in ways that more highbrow literary texts may not. Robin Cook's 1977 novel Coma exemplifies the ways in which medical thrillers participate in the public discourse about health care. Written shortly after the medical establishment promoted "irreversible...

journal_title：Perspectives in biology and medicine

authors： Belling C

更新日期：2010-07-01 00:00:00

abstract：:Over time, contemporary writing becomes part of the historical record. In medicine, it is an important learning tool, particularly for understanding the experience and context of disease and illness. Although a century has elapsed since the fictional events on a single day described in James Joyce's Ulysses, the work ...

journal_title：Perspectives in biology and medicine

authors： Shanahan F,Quigley EM

更新日期：2006-04-01 00:00:00

abstract：:Biologists use models in two distinct ways that have not been clearly articulated. A model may be used either as an exemplar of a larger group, or as a surrogate for a specific target. Zebrafish serve as an exemplary model of vertebrates in developmental biology; rodents are both exemplary vertebrates and specific sur...

journal_title：Perspectives in biology and medicine

authors： Bolker JA

更新日期：2009-10-01 00:00:00

abstract：:This paper constructs a brief history of the biochemical term agonist by exploring the multiple meanings of the root agôn in ancient Greek literature and describing how agonist first appeared in the scientific literature of the 20th century in the context of neurophysiologists' debates about the existence and properti...

journal_title：Perspectives in biology and medicine

authors： Russo R

更新日期：2002-07-01 00:00:00

abstract：:The traditional forms of public health law were directed largely toward communicable diseases and other externalities, such as pollution, with negative health impacts. The more modern view treats any health issue that affects large numbers of individuals as one of public health, which would include such problems as ob...

journal_title：Perspectives in biology and medicine

authors： Epstein RA

更新日期：2003-07-01 00:00:00

abstract：:The concept and determination of death by neurological or cardio-circulatory criteria play a crucial role for medical practice, society, and the law. Academic debates on death determination have regained momentum, and recent cases involving the neurological determination of death ("brain death") in the United States h...

journal_title：Perspectives in biology and medicine

authors： Racine E,Jox RJ,Bernat JL,Dabrock P,Gardiner D,Marckmann G,Rid A,Rodriguez-Arias D,Schmitten RI,Schöne-Seifert B

更新日期：2015-01-01 00:00:00

abstract：:This article proposes a means for better understanding the self and consciousness. Data indicate that the basic "emotional brain" continually computes potential survival risk against reward to rank consequent "emotion scores" for all sensory inputs. These scores compete to yield winner-takes-all outcomes that determin...

journal_title：Perspectives in biology and medicine

authors： Boyd GW

更新日期：2012-07-01 00:00:00

abstract：:The impact of chronic illness on patients has been discussed extensively, but little attention has been paid to the reverse situation: the need for patients who have been chronically ill since childhood to adjust to health and normality in adulthood. Drawing upon the narratives of two adults with childhood onset disea...

journal_title：Perspectives in biology and medicine

authors： Orfali K,Anderson-Shaw L

更新日期：2005-04-01 00:00:00

abstract：:Marino Ortolani (1904-1983), a pediatrician from Ferrara, in northeastern Italy, was an outstanding pioneer in the early diagnosis and treatment of hip dysplasia. In 1935, while examining hip abduction-adduction in a six-month-old baby, Ortolani noted that a clearly audible and palpable "click" was sufficient to revea...

journal_title：Perspectives in biology and medicine

authors： Stecco C,Porzionato A,Macchi V,Fantoni I,Ortolani L,De Caro R

更新日期：2014-10-01 00:00:00

abstract：:The idea of being "haunted" appears often in accounts of the experience of health-care professionals and trainees who suffer from unresolved sorrow or regret about past clinical events, in particular the deaths of patients. The trope of haunting draws a direct line between past professional trauma and the dread of fut...

journal_title：Perspectives in biology and medicine

authors： Belling C

更新日期：2020-01-01 00:00:00

abstract：:Several studies suggest that clinical researchers are prone to overestimating the chance that scientific protocols will succeed, say, by confirming a treatment hypothesis or reaching recruitment targets. In this essay, we address the normative question of whether such "unrealistic optimism" is harmful in clinical rese...

journal_title：Perspectives in biology and medicine

authors： Benjamin D,Kimmelman J

更新日期：2016-01-01 00:00:00

abstract：:This article reviews the cultural history of man's relationship with tobacco and the steps in the discovery of tobacco addiction. Nicotine dependence (ND) or nicotine addiction (NA), among other forms of drug addiction, continues to be a significant public health problem in the world, as it is associated with major se...

journal_title：Perspectives in biology and medicine

authors： Russo P,Nastrucci C,Alzetta G,Szalai C

更新日期：2011-10-01 00:00:00

abstract：:The clinical trial of the AbioCor artificial heart, initiated in July 2001 and still in process, has taken place within a matrix of social and cultural patterns that are both "old" and new. The old patterns--those that have accompanied previous clinical trials of other vital artificial organs and transplantation in th...

journal_title：Perspectives in biology and medicine

authors： Fox RC,Swazey JP

更新日期：2004-01-01 00:00:00

abstract：:The rise of big data and artificial intelligence (AI) in health care has engendered considerable excitement, claiming to improve approaches to diagnosis, prognosis, and treatment. Amidst the enthusiasm, the philosophical assumptions that underlie the big data and AI movement in medicine are rarely examined. This essay...

journal_title：Perspectives in biology and medicine

authors： Chin-Yee B,Upshur R

更新日期：2019-01-01 00:00:00

abstract：:A detailed review of hospital records, physician's notes, diaries, letters, and autopsy reports offers sufficient clinical grounds to establish that Eugene O'Neill developed adrenal insufficiency, secondary to tuberculosis, in later life--a fact hitherto unknown--the condition not becoming manifest until after he had ...

journal_title：Perspectives in biology and medicine

authors： Hamilton JW

更新日期：1987-01-01 00:00:00