Characteristics of an OSLD in the diagnostic energy range.

Abstract:

PURPOSE:Optically stimulated luminescence (OSL) dosimetry has been recently introduced in radiation therapy as a potential alternative to the thermoluminescent dosimeter (TLD) system. The aim of this study was to investigate the feasibility of using OSL point dosimeters in the energy range used in diagnostic imaging. METHODS:NanoDot OSL dosimeters (OSLDs) were used in this study, which started with testing the homogeneity of a new packet of nanoDots. Reproducibility and the effect of optical treatment (bleaching) were then examined, followed by an investigation of the effect of accumulated dose on the OSLD indicated doses. OSLD linearity, angular dependence, and energy dependence were also studied. Furthermore, comparison with LiF:Mg,Ti TLD chips using standard CT dose phantoms at 80 and 120 kVp settings was performed. RESULTS:Batch homogeneity showed a coefficient of variation of <5%. Single-irradiation measurements with bleaching after each OSL readout was found to be associated with a 3.3% reproducibility (one standard deviation measured with a 8 mGy test dose), and no systematic change in OSLDs sensitivity could be noted from measurement to measurement. In contrast, the multiple-irradiation readout without bleaching in between measurements was found to be associated with an uncertainty (using a 6 mGy test dose) that systematically increased with accumulated dose, reaching 42% at 82 mGy. Good linearity was shown by nanoDots under general x-ray, CT, and mammography units with an R2 > 0.99. The angular dependence test showed a drop of approximately 70% in the OSLD response at 90 degrees in mammography (25 kVp). With the general radiography unit, the maximum drop was 40% at 80 kVp and 20% at 120 kVp, and it was only 10% with CT at both 80 and 120 kVp. The energy dependence study showed a range of ion chamber-to-OSLDs ratios between 0.81 and 1.56, at the energies investigated (29-62 keV). A paired t-test for comparing the OSLDs and TLDs showed no significant variation (p > 0.1). CONCLUSIONS:OSLDs exhibited good batch homogeneity (<5%) and reproducibility (3.3%), as well as a linear response. In addition, they showed no statistically significant difference with TLDs in CT measurements (p > 0.1). However, high uncertainty (42%) in the dose estimate was found as a result of relatively high accumulated dose. Furthermore, nanoDots showed high angular dependence (up to 70%) in low kVp techniques. Energy dependence of about 60% was found, and correction factors were suggested for the range of energies investigated. Therefore, if angular and energy dependences are taken into consideration and the uncertainty associated with accumulated dose is avoided, OSLDs (nanoDots) can be suitable for use as point dosimeters in diagnostic settings.

journal_name

Med Phys

journal_title

Medical physics

authors

Al-Senan RM,Hatab MR

doi

10.1118/1.3602456

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

4396-405

issue

7

eissn

0094-2405

issn

2473-4209

journal_volume

38

pub_type

杂志文章
  • Photon attenuation in computed tomography.

    abstract::The analysis and understanding of results of computed tomography (CT) require an understanding of photon attenuation in matter. The high sensitivity and resolution of these devices coupled with the use of a polychromatic photon source require a level and breadth of understanding about photon attenuation not usually re...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594199

    authors: McCullough EC

    更新日期:1975-11-01 00:00:00

  • On the effective point of measurement in megavoltage photon beams.

    abstract::This paper presents a numerical investigation of the effective point of measurement of thimble ionization chambers in megavoltage photon beams using Monte Carlo simulations with the EGSNRC system. It is shown that the effective point of measurement for relative photon beam dosimetry depends on every detail of the cham...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2201147

    authors: Kawrakow I

    更新日期:2006-06-01 00:00:00

  • Measurement of primary bremsstrahlung spectrum from an 8-MeV linear accelerator.

    abstract::The bremsstrahlung spectrum from an 8-MeV linear accelerator has been measured using a NaI(T1) spectrometer system. The spectrum shows a low-energy cutoff at 0.4 MeV and the maximum photon energy to be approximately 6% greater than the nominal energy. The maximum emission of energy fluence was 1.6 and 1.8 MeV for meas...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594221

    authors: Levy LB,Waggener RG,Wright AE

    更新日期:1976-05-01 00:00:00

  • Technical Note: modification of the standard gain correction algorithm to compensate for the number of used reference flat frames in detector performance studies.

    abstract:PURPOSE:The x-ray performance evaluation of digital x-ray detectors is based on the calculation of the modulation transfer function (MTF), the noise power spectrum (NPS), and the resultant detective quantum efficiency (DQE). The flat images used for the extraction of the NPS should not contain any fixed pattern noise (...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3664003

    authors: Konstantinidis AC,Olivo A,Speller RD

    更新日期:2011-12-01 00:00:00

  • Experimental characterization of the miniannular phased array as a hyperthermia applicator.

    abstract::A series of experiments has been carried out in order to characterize a miniannular phased array applicator prior to possible clinical implementation. The energy deposition patterns over the frequency range of 100 to 200 MHz were determined in several human limb models of different complexities by measuring the electr...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596037

    authors: Guerquin-Kern JL,Hagmann MJ,Levin RL

    更新日期:1987-07-01 00:00:00

  • QA procedures for multimodality preclinical tumor drug response testing.

    abstract:PURPOSE:There are growing expectations that imaging biomarkers for tumor therapeutic drug response assessment will speed up preclinical testing of anticancer drugs in rodent models. The only imaging biomarker presently approved by the U.S. Food and Drug Administration is tumor size measurement based on either World Hea...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3464491

    authors: Lee YC,Goins BA,Fullerton GD

    更新日期:2010-09-01 00:00:00

  • The influence of phantom size on output, peak scatter factor, and percentage depth dose in large-field photon irradiation.

    abstract::Machine outputs, peak scatter factors, and central axis percentage depth dose distributions were measured for various phantom sizes in large radiation fields produced at extended distances by cobalt, 6-MV, and 10-MV photon beams. The results can be applied to practical total body irradiation procedures which usually i...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595686

    authors: Podgorsak EB,Pla C,Evans MD,Pla M

    更新日期:1985-09-01 00:00:00

  • Age-dependent dose calculations for common PET radionuclides and brain radiotracers in nonhuman primate computational models.

    abstract:PURPOSE:The combination of nonhuman primates (NHPs) with the state-of-the-art molecular imaging technologies allows for within-subject longitudinal research aiming at gaining new insights into human normal and disease conditions and provides an ideal foundation for future translational studies of new diagnostic tools, ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14333

    authors: Xie T,Chen X,Zaidi H

    更新日期:2020-09-01 00:00:00

  • Towards Data-Efficient Learning: A Benchmark for COVID-19 CT Lung and Infection Segmentation.

    abstract:PURPOSE:Accurate segmentation of lung and infection in COVID-19 computed tomography (CT) scans plays an important role in the quantitative management of patients. Most of the existing studies are based on large and private annotated datasets that are impractical to obtain from a single institution, especially when radi...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14676

    authors: Ma J,Wang Y,An X,Ge C,Yu Z,Chen J,Zhu Q,Dong G,He J,He Z,Cao T,Zhu Y,Nie Z,Yang X

    更新日期:2020-12-23 00:00:00

  • Quantitative modeling of the accuracy in registering preoperative patient-specific anatomic models into left atrial cardiac ablation procedures.

    abstract:PURPOSE:In cardiac ablation therapy, accurate anatomic guidance is necessary to create effective tissue lesions for elimination of left atrial fibrillation. While fluoroscopy, ultrasound, and electroanatomic maps are important guidance tools, they lack information regarding detailed patient anatomy which can be obtaine...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4861712

    authors: Rettmann ME,Holmes DR 3rd,Kwartowitz DM,Gunawan M,Johnson SB,Camp JJ,Cameron BM,Dalegrave C,Kolasa MW,Packer DL,Robb RA

    更新日期:2014-02-01 00:00:00

  • Correcting and reweighting false label masks in brain tumor segmentation.

    abstract:PURPOSE:Recently, brain tumor segmentation has made important progress. However, the quality of manual labels plays an important role in the performance, while in practice, it could vary greatly and in turn could substantially mislead the learning process and decrease the accuracy. We need to design a mechanism to comb...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14480

    authors: Cheng G,Ji H,He L

    更新日期:2020-09-24 00:00:00

  • Delivery validation of an automated modulated electron radiotherapy plan.

    abstract:PURPOSE:Modulated electron radiation therapy (MERT) represents an active area of interest that offers the potential to improve healthy tissue sparing in treatment of certain cancer cases. Challenges remain however in accurate beamlet dose calculation, plan optimization, collimation method, and delivery accuracy. In thi...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4876297

    authors: Connell T,Alexander A,Papaconstadopoulos P,Serban M,Devic S,Seuntjens J

    更新日期:2014-06-01 00:00:00

  • Feasibility of a simple method of hybrid collimation for megavoltage grid therapy.

    abstract:PURPOSE:Megavoltage grid therapy is currently delivered with step-and-shoot multisegment techniques or using a high attenuation block with divergent holes. However, the commercial availability of grid blocks is limited, their construction is difficult, and step-and-shoot techniques require longer treatment times and ar...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4801902

    authors: Almendral P,Mancha PJ,Roberto D

    更新日期:2013-05-01 00:00:00

  • Off-axis beam quality change in linear accelerator x-ray beams.

    abstract::The effective energy of the x-ray beam from linear accelerators changes as a function of the position in the beam due to nonuniform filtration by the flattening filter. In this work, the transmittance through a water column was measured in good geometry and the beam quality characterized in units of HVL in water. Meas...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594677

    authors: Hanson WF,Berkley LW,Peterson M

    更新日期:1980-03-01 00:00:00

  • Measurement of absorbed dose-to-water for an HDR (192)Ir source with ionization chambers in a sandwich setup.

    abstract:PURPOSE:In this study, a dedicated device for ion chamber measurements of absorbed dose-to-water for a Nucletron microSelectron-v2 HDR (192)Ir brachytherapy source is presented. The device uses two ionization chambers in a so-called sandwich assembly. Using this setup and by taking the average reading of the two chambe...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4816673

    authors: Araki F,Kouno T,Ohno T,Kakei K,Yoshiyama F,Kawamura S

    更新日期:2013-09-01 00:00:00

  • Evaluation of delivered monitor unit accuracy of gated step-and-shoot IMRT using a two-dimensional detector array.

    abstract:PURPOSE:To overcome the problem of organ motion in intensity-modulated radiation therapy (IMRT), gated IMRT is often used for the treatment of lung cancer. In this study, the authors investigated the accuracy of the delivered monitor units (MUs) from each segment during gated IMRT using a two-dimensional detector array...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3310806

    authors: Cheong KH,Kang SK,Lee M,Kim SS,Park S,Hwang TJ,Kim KJ,Oh DH,Bae H,Suh TS

    更新日期:2010-03-01 00:00:00

  • Dosimetric effect of respiration-gated beam on IMRT delivery.

    abstract::Intensity modulated radiation therapy (IMRT) with a dynamic multileaf collimator (DMLC) requires synchronization of DMLC leaf motion with dose delivery. A delay in DMLC communication is known to cause leaf lag and lead to dosimetric errors. The errors may be exacerbated by gated operation. The purpose of this study wa...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1592017

    authors: Duan J,Shen S,Fiveash JB,Brezovich IA,Popple RA,Pareek PN

    更新日期:2003-08-01 00:00:00

  • High dose-per-pulse electron beam dosimetry: Usability and dose-rate independence of EBT3 Gafchromic films.

    abstract:PURPOSE:The aim of this study was to assess the suitability of Gafchromic EBT3 films for reference dose measurements in the beam of a prototype high dose-per-pulse linear accelerator (linac), capable of delivering electron beams with a mean dose-rate (Ḋm ) ranging from 0.07 to 3000 Gy/s and a dose-rate in pulse (Ḋp ) o...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12066

    authors: Jaccard M,Petersson K,Buchillier T,Germond JF,Durán MT,Vozenin MC,Bourhis J,Bochud FO,Bailat C

    更新日期:2017-02-01 00:00:00

  • Three dimensional intensity modulated brachytherapy (IMBT): dosimetry algorithm and inverse treatment planning.

    abstract:PURPOSE:The feasibility of intensity modulated brachytherapy (IMBT) to improve dose conformity for irregularly shaped targets has been previously investigated by researchers by means of using partially shielded sources. However, partial shielding does not fully explore the potential of IMBT. The goal of this study is t...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3456598

    authors: Shi C,Guo B,Cheng CY,Esquivel C,Eng T,Papanikolaou N

    更新日期:2010-07-01 00:00:00

  • Calculation of photon energy deposition kernels and electron dose point kernels in water.

    abstract::Effects of changes in the physics of EGSnrc compared to EGS4/PRESTA on energy deposition kernels for monoenergetic photons and on dose point kernels for beta sources in water are investigated. In the diagnostic energy range, Compton binding corrections were found to increase the primary energy fraction up to 4.5% at 3...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1861412

    authors: Mainegra-Hing E,Rogers DW,Kawrakow I

    更新日期:2005-03-01 00:00:00

  • Feasibility of real-time lung tumor motion monitoring using intrafractional ultrasound and kV cone beam projection images.

    abstract:PURPOSE:The ability to monitor intrafractional tumor motion is essential for radiation therapy of thoracic and abdominal tumors. This study aims to develop a method to track lung tumor motion using intrafractional continuous ultrasound (US) and periodic cone-beam projection images (CBPI). METHODS:Time-sequenced b-mode...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13104

    authors: Mostafaei F,Tai A,Gore E,Johnstone C,Haase W,Ehlers C,Cooper DT,Lachaine M,Li XA

    更新日期:2018-10-01 00:00:00

  • A material sensitivity study on the accuracy of deformable organ registration using linear biomechanical models.

    abstract::Model-based deformable organ registration techniques using the finite element method (FEM) have recently been investigated intensively and applied to image-guided adaptive radiotherapy (IGART). These techniques assume that human organs are linearly elastic material, and their mechanical properties are predetermined. U...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2163838

    authors: Chi Y,Liang J,Yan D

    更新日期:2006-02-01 00:00:00

  • Characteristics of metal-plate/film detectors at therapy energies. II. Detective quantum efficiency.

    abstract::Noise power spectrum (NPS) and detective quantum efficiency (DQE) for metal-plate/film portal detectors are reported for the Co-60 and Linac 10 MV spectra. The detectors consist of a double-emulsion portal film secured between plates of aluminum, copper, brass, or lead. The NPS was found to be independent of the detec...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598437

    authors: Falco T,Fallone BG

    更新日期:1998-12-01 00:00:00

  • SU-E-T-459: Radiobiological Evaluation of Implant Duration and Radionuclide Selection for COMS Eye Plaque Brachytherapy Using an Objective Function.

    abstract:PURPOSE:The biologically effective dose (BED) of temporary brachytherapy treatments is a function of both chosen radionuclide (R) and implant duration (T). This study endeavored to evaluate BED delivered to the tumor volume and surrounding ocular structures as a function of plaque position (P), prescription dose, R, an...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735548

    authors: Gagne N,Rivard M

    更新日期:2012-06-01 00:00:00

  • Physics process level discrimination of detections for GATE: assessment of contamination in SPECT and spurious activity in PET.

    abstract::The GEANT4 application for tomographic emission (GATE) is one of the most detailed Monte Carlo simulation tools for SPECT and PET. It allows for realistic phantoms, complex decay schemes, and a large variety of detector geometries. However, only a fraction of the information in each particle history is available for p...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3078045

    authors: De Beenhouwer J,Staelens S,Vandenberghe S,Verhaeghe J,Van Holen R,Rault E,Lemahieu I

    更新日期:2009-04-01 00:00:00

  • A comparative contrast-detail study of five medical displays.

    abstract::The objective of this study was to compare the contrast-detail performance of five different commercial liquid crystal displays (LCDs) to other LCD and cathode-ray tube (CRT) displays for medical applications. A contrast-detail phantom, supplemented with 5 in. of acrylic, was imaged on a commercial digital radiographi...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2868780

    authors: Samei E,Ranger NT,Delong DM

    更新日期:2008-04-01 00:00:00

  • SU-F-BRCD-09: Total Variation (TV) Based Fast Convergent Iterative CBCT Reconstruction with GPU Acceleration.

    abstract:PURPOSE:To improve image quality and reduce imaging dose in CBCT for radiation therapy applications and to realize near real-time image reconstruction based on use of a fast convergence iterative algorithm and acceleration by multi-GPUs. METHODS:An iterative image reconstruction that sought to minimize a weighted leas...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735747

    authors: Xu Q,Yang D,Tan J,Anastasio M

    更新日期:2012-06-01 00:00:00

  • Second cancer incidence risk estimates using BEIR VII models for standard and complex external beam radiotherapy for early breast cancer.

    abstract:PURPOSE:To compare organ specific cancer incidence risks for standard and complex external beam radiotherapy (including cone beam CT verification) following breast conservation surgery for early breast cancer. METHOD:Doses from breast radiotherapy and kilovoltage cone beam CT (CBCT) exposures were obtained from thermo...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4748332

    authors: Donovan EM,James H,Bonora M,Yarnold JR,Evans PM

    更新日期:2012-10-01 00:00:00

  • Monte Carlo simulations on the water-to-air stopping power ratio for carbon ion dosimetry.

    abstract::Many papers discussed the I value for water given by the ICRU, concluding that a value of about 80 +/- 2 eV instead of 67.2 eV would reproduce measured ion depth-dose curves. A change in the I value for water would have an effect on the stopping power and, hence, on the water-to-air stopping power ratio, which is impo...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3085877

    authors: Henkner K,Bassler N,Sobolevsky N,Jäkel O

    更新日期:2009-04-01 00:00:00

  • Improved MAGIC gel for higher sensitivity and elemental tissue equivalent 3D dosimetry.

    abstract:PURPOSE:Polymer-based gel dosimeter (MAGIC type) is a preferable phantom material for PET range verification of proton beam therapy. However, improvement in elemental tissue equivalency (specifically O/C ratio) is very desirable to ensure realistic time-activity measurements. METHODS:Glucose and urea was added to the ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3260844

    authors: Zhu X,Reese TG,Crowley EM,El Fakhri G

    更新日期:2010-01-01 00:00:00